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Rheumatology
Nailfold capillaroscopy findings of interstitial pneumonia with autoimmune features
Sang-Heon Lee, Hong Ki Min, Se-Hee Kim, Young Whan Kim, Kwang Ha Yoo, Hee Joung Kim, In Ae Kim, Hae-Rim Kim
Korean J Intern Med. 2023;38(6):903-911. Published online July 25, 2023
Background/Aims: We evaluated nailfold capillaroscopy (NFC) of interstitial pneumonia with autoimmune features (IPAF) and compared it with that of patients with connective tissue disease-interstitial lung disease (CTD-ILD) and idiopathic interstitial pneumonia (IIP).
Methods: Patients with newly di..
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Comparative effectiveness of JAK inhibitors and biologic disease-modifying antirheumatic drugs in patients with rheumatoid arthritis
Soo-Kyung Cho, Hyoungyoung Kim, Yeo-Jin Song, Hye Won Kim, Eunwoo Nam, Shin-Seok Lee, Hye-Soon Lee, Sung-Hoon Park, Yeon-Ah Lee, Min-Chan Park, Sung Hae Chang, Hyoun-Ah Kim, Seung-Ki Kwok, Hae-Rim Kim, Hyun-Sook Kim, Bo Young Yoon, Wan-Sik Uhm, Yong-Gil Kim, Jae Hoon Kim, Jisoo Lee, Jeongim Choi, Yoon-Kyoung Sung
Korean J Intern Med. 2023;38(4):546-556. Published online June 20, 2023
Background/Aims: We aimed to compare the effectiveness and safety of Janus kinase inhibitors (JAKi) vs. biologic disease- modifying antirheumatic drugs (bDMARD) in Korean patients with rheumatoid arthritis (RA) who had an inadequate response to conventional synthetic DMARDs.
Methods: A quasi-exper..
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Musculoskeletal complications in patients with diabetes mellitus
Jong Han Choi, Hae-Rim Kim, Kee-Ho Song
Korean J Intern Med. 2022;37(6):1099-1110. Published online October 27, 2022
Musculoskeletal conditions are common in patients with diabetes. Several musculoskeletal disorders are viewed as chronic complications of diabetes because epidemiological studies have revealed high correlations between such complications and diabetes, but the pathophysiological links with diabetes r..
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Perioperative and anesthetic management of patients with rheumatoid arthritis
Hae-Rim Kim, Seong-Hyop Kim
Korean J Intern Med. 2022;37(4):732-739. Published online June 3, 2022
Our understanding and management of rheumatoid arthritis (RA) have greatly improved, but perioperative and anesthetic management remain challenging. RA is not limited to joints; systemic evaluation is thus required when planning perioperative management. Especially, careful airway evaluation is need..
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Rheumatology
Tocotrienol regulates osteoclastogenesis in rheumatoid arthritis
Kyoung-Woon Kim, Bo-Mi Kim, Ji-Yeon Won, Hong Ki Min, Seoung Joon Lee, Sang-Heon Lee, Hae-Rim Kim
Korean J Intern Med. 2021;36(Suppl 1):S273-S282. Published online June 19, 2020
Background/Aims: The present study aimed to investigate whether tocotrienol regulates interleukin 17 (IL-17)-induced osteoclastogenesis in rheumatoid arthritis (RA).
Methods: We evaluated the effect of tocotrienol on IL-17-induced receptor activator of nuclear factor kappa B ligand (RANKL) producti..
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Shingles in palmar cutaneous branch of ulnar nerve
Hong Ki Min, Se Hee Kim, Sang-Heon Lee, Hae-Rim Kim
Korean J Intern Med. 2021;36(4):1029-1030. Published online April 22, 2020
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Recent advances in the diagnosis and management of interstitial pneumonia with autoimmune features: the perspective of rheumatologists
Hong Ki Min, Se-Hee Kim, Sang-Heon Lee, Hae-Rim Kim
Korean J Intern Med. 2021;36(3):515-526. Published online February 8, 2021
Interstitial pneumonia with autoimmune feature (IPAF) is a recently established disease entity that is comprised of interstitial lung diseases with evidence of autoimmune features but that does not fulfill the criteria for definite autoimmune rheumatic diseases. The classification criteria for IPAF ..
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Definite visualized communication of a Baker’s cyst with knee joint space and iatrogenic air content in rheumatoid arthritis patient
Hong Ki Min, Se Hee Kim, Sung Gyu Moon, Hae-Rim Kim, Sang-Heon Lee
Korean J Intern Med. 2020;35(5):1254-1255. Published online August 19, 2019
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Roles of mast cells in rheumatoid arthritis
Hong Ki Min, Kyoung-Woon Kim, Sang-Heon Lee, Hae-Rim Kim
Korean J Intern Med. 2020;35(1):12-24. Published online November 15, 2019
Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory arthritis, and the complex interaction and activation of innate and adaptive immune cells are involved in RA pathogenesis. Mast cells (MCs) are one of the tissue-resident innate immune cells, and they contribute to RA pathogenesis. In th..
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Rheumatology
Standardized, musculoskeletal ultrasonographic reference values for healthy Korean adults
Hyun-Sook Kim, Hae-Rim Kim, Bo Young Kim, Yun Sung Kim, Young Ok Jung, Sung Jae Choi, Hyun-Ok Kim, Jiwon Hwang, Sunggun Lee, Hyoun-Ah Kim, So Young Bang, Ji-Young Chai, Sung-Hoon Park, Chong-Hyeon Yoon
Korean J Intern Med. 2019;34(6):1372-1380. Published online May 4, 2018
Background/Aims: To define standard reference values for musculoskeletal ultrasonography (MSUS) in Korea.
Methods: A total of 251 healthy adults were recruited for this study. Ultrasonography was performed by experienced rheumatologists who had undergone four appropriate training programs in Korea..
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Rheumatic complications in cancer patients treated with immune checkpoint inhibitors
Kyung-Ann Lee, Hae-Rim Kim, So Young Yoon
Korean J Intern Med. 2019;34(6):1197-1209. Published online April 25, 2019
Immune checkpoint inhibitors (ICIs) have revolutionized anticancer therapy due to their long-term clinical benefits and immune boosting mechanisms. However, despite their consistent therapeutic effects, the use of ICIs is associated with a spectrum of adverse events due to their autoimmune and auto-..
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Rheumatology
Magnetic resonance imaging-assessed synovial and bone changes in hand and wrist joints of rheumatoid arthritis patients
Kyung-Ann Lee, Sang-Ho Min, Tae-Hyung Kim, Sang-Heon Lee, Hae-Rim Kim
Korean J Intern Med. 2019;34(3):651-659. Published online November 24, 2017
Background/Aims: Magnetic resonance imaging (MRI) is a sensitive and useful method for the detection of synovitis and joint destruction in rheumatoid arthritis (RA) patients. However, the patterns of MRI-detected bone erosion, bone marrow edema (BME), synovitis, and tenosynovitis have received insuf..
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N-acetyl-l-cysteine controls osteoclastogenesis through regulating Th17 differentiation and RANKL production in rheumatoid arthritis
Hae-Rim Kim, Kyoung-Woon Kim, Bo-Mi Kim, Kyung-Ann Lee, Sang-Heon Lee
Korean J Intern Med. 2019;34(2):458-458. Published online February 25, 2019
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Rheumatology
N-acetyl-l-cysteine controls osteoclastogenesis through regulating Th17 differentiation and RANKL in rheumatoid arthritis
[corrected-article]
Hae-Rim Kim, Kyoung-Woon Kim, Bo-Mi Kim, Kyung-Ann Lee, Sang-Heon Lee
Korean J Intern Med. 2019;34(1):210-219. Published online March 13, 2017
Background/Aims: This study aimed to determine the regulatory role of N-acetyl-l-cysteine (NAC), an antioxidant, in interleukin 17 (IL-17)-induced osteoclast differentiation in rheumatoid arthritis (RA).
Methods: After RA synovial fibroblasts were stimulated by IL-17, the expression and pro..
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Macrophage migration inhibitory factor: a potential therapeutic target for rheumatoid arthritis
Kyoung-Woon Kim, Hae-Rim Kim
Korean J Intern Med. 2016;31(4):634-642. Published online May 12, 2016
Macrophage migration inhibitory factor (MIF) is originally identified in the culture medium of activated T lymphocytes as a soluble factor that inhibits the random migration of macrophages. MIF is now recognized as a multipotent cytokine involved in the regulation of immune and inf lammatory respons..
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Rhupus syndrome
Jae Ki Min, Kyoung Ann Lee, Hae-Rim Kim, Ho-Youn Kim, Sang-Heon Lee
Korean J Intern Med. 2015;30(1):131-131. Published online December 30, 2014
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Detection of calcium pyrophosphate dihydrate crystal deposition disease by dual-energy computed tomography
Hae-Rim Kim, Jung-Hwa Lee, Na Ra Kim, Sang-Heon Lee
Korean J Intern Med. 2014;29(3):404-405. Published online April 29, 2014
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Induction of Macrophage Migration Inhibitory Factor in ConA-Stimulated Rheumatoid Arthritis Synovial Fibroblasts through the P38 MAP Kinase-Dependent Signaling Pathway
Hae-Rim Kim, Mi-Kyung Park, Mi-La Cho, Kyoung-Woon Kim, Hye-Joa Oh, Jin-Sil Park, Yang-Mi Heo, Sang-Heon Lee, Ho-Youn Kim, Sung-Hwan Park
Korean J Intern Med. 2010;25(3):317-326. Published online August 31, 2010
Background/AimsThis study was undertaken to identify the intracellular signaling pathway involved in induction of macrophage migration inhibitory factor (MIF) in human rheumatoid arthritis (RA) synovial fibroblasts. MethodsHuman RA synovial fibr..
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