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Hemato-oncology
Rituximab plus multiagent chemotherapy for newly diagnosed CD20-positive acute lymphoblastic leukemia: a prospective phase II study
Dong Won Baek, Han-Seung Park, Sang Kyun Sohn, Dae Young Kim, Inho Kim, Jae-Sook Ahn, Young Rok Do, Se Ryeon Lee, Hyeon-Seok Eom, Won-Sik Lee, Sung-Hyun Kim, Ho Sup Lee, Yoo Jin Lee, Joon Ho Moon, Je-Hwan Lee; Adult Acute Lymphoblastic Leukemia Working Party, the Korean Society of Hematology
Korean J Intern Med. 2023;38(5):734-746. Published online June 20, 2023
Background/Aims: We performed a prospective study to determine the efficacy and safety of rituximab including chemotherapy in CD20-positive acute lymphoblastic leukemia (ALL).
Methods: Patients with newly diagnosed ALL, aged ≥ 15 years, were eligible for the study if their leukemic blast cells in ..
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Predictive role of absolute lymphocyte count in daratumumab-treated patients with relapsed/refractory multiple myeloma
Hee Jeong Cho, Jae-Cheol Jo, Yoo Jin Lee, Myung Won Lee, Do Young Kim, Ho Jin Shin, Sung Nam Im, Ji Hyun Lee, Sung Hwa Bae, Young Rok Do, Won Sik Lee, Min Kyung Kim, Jina Jung, Jung Min Lee, Ju-Hyung Kim, Dong Won Baek, Sang-Kyun Sohn, Joon Ho Moon
Korean J Intern Med. 2023;38(4):578-578. Published online June 9, 2023
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Hemato-oncology
Predictive role of absolute lymphocyte count in daratumumab-treated patients with relapsed/ refractory multiple myeloma
[corrected-article]
Hee Jeong Cho, Jae-Cheol Jo, Yoo Jin Lee, Myung Won Lee, Do Young Kim, Ho Jin Shin, Sung Nam Im, Ji Hyun Lee, Sung Hwa Bae, Young Rok Do, Won Sik Lee, Min Kyung Kim, Jina Jung, Jung Min Lee, Ju-Hyung Kim, Dong Won Baek, Sang-Kyun Sohn, Joon Ho Moon
Korean J Intern Med. 2023;38(2):238-247. Published online January 26, 2023
Background/Aims: Daratumumab has shown an encouraging antitumor effect in patients with multiple myeloma (MM), and was known to alter the immune properties by off-targeting immunosuppressive cells. Here, we aimed to evaluate the change in absolute lymphocyte count (ALC) as a surrogate marker for pre..
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Pediatric-inspired regimen with late intensification and increased dose of L-asparaginase for adult acute lymphoblastic leukemia: the KALLA 1406/1407 study
Dong Won Baek, Dae Young Kim, Sang Kyun Sohn, Youngil Koh, Sung-Hoon Jung, Ho-Young Yhim, Yunsuk Choi, Joon Ho Moon
Korean J Intern Med. 2021;36(6):1471-1485. Published online September 24, 2021
Background/Aims: The objective of this study was to evaluate the efficacy and feasibility of the pediatric-inspired regimen of the adult acute lymphoblastic leukemia (ALL) Working Party, the Korean Society of Hematology.
Methods: Data of 99 patients with newly diagnosed ALL, who were treated with t..
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No benefit of hypomethylating agents compared to supportive care for higher risk myelodysplastic syndrome
Sang Kyun Sohn, Joon Ho Moon, In Hee Lee, Jae Sook Ahn, Hyeoung Joon Kim, Joo Seop Chung, Ho Jin Shin, Sung Woo Park, Won Sik Lee, Sang Min Lee, Hawk Kim, Ho Sup Lee, Yang Soo Kim, Yoon Young Cho, Sung Hwa Bae, Ji Hyun Lee, Sung Hyun Kim, Ik Chan Song, Ji Hyun Kwon, Yoo Jin Lee
Korean J Intern Med. 2018;33(6):1194-1202. Published online December 15, 2017
Background/Aims: This study evaluated the role of hypomethylating agents (HMA) compared to best supportive care (BSC) for patients with high or very-high (H/VH) risk myelodysplastic syndrome (MDS) according to the Revised International Prognostic Scoring System.
Methods: A total of 279 H/VH risk MD..
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New synergistic efficacy of combination of romiplostim and steroid in refractory immune thrombocytopenia patients
Jun Seok Yoon, Yoo Jin Lee, Dong Won Baek, Hye Young Park, Bo Eun Park, Joon Ho Moon, Sang Kyun Sohn
Korean J Intern Med. 2018;33(2):435-437. Published online March 7, 2016
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Gastroenterology
Prevention of type 2 diabetes mellitus in women with previous gestational diabetes mellitus
Joon Ho Moon, Soo Heon Kwak, Hak C. Jang
Korean J Intern Med. 2017;32(1):26-41. Published online January 1, 2017
Gestational diabetes mellitus (GDM), defined as any degree of glucose intolerance with onset or first recognition during pregnancy, is characterized by underlying maternal defects in the β-cell response to insulin during pregnancy. Women with a previous history of GDM have a greater than 7-fold hi..
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Expressive aphasia as the manifestation of hyperglycemic crisis in type 2 diabetes
Ji Hyun Lee, Ye An Kim, Joon Ho Moon, Se Hee Min, Young Shin Song, Sung Hee Choi
Korean J Intern Med. 2016;31(6):1187-1190. Published online March 12, 2016
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First Korean case of Emberger syndrome (primary lymphedema with myelodysplasia) with a novel GATA2 gene mutation
Sang Kyung Seo, Kyu Yeun Kim, Seo Ae Han, Joon Seok Yoon, Sang-Yong Shin, Sang Kyun Sohn, Joon Ho Moon
Korean J Intern Med. 2016;31(1):188-190. Published online December 28, 2015
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An insulinoma with an aberrant feeder from the splenic artery detected by super-selective arterial calcium stimulation with venous sampling
Joon Ho Moon, Eun Ky Kim, Ah Reum Khang, Hyo-Cheol Kim, Jin-Young Jang, Young Min Cho
Korean J Intern Med. 2015;30(1):118-121. Published online December 30, 2014
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Hemato-oncology
Clinical significance of nuclear factor κB and chemokine receptor CXCR4 expression in patients with diffuse large B-cell lymphoma who received rituximab-based therapy
Ho Cheol Shin, Jongwon Seo, Byung Woog Kang, Joon Ho Moon, Yee Soo Chae, Soo Jung Lee, Yoo Jin Lee, Seoae Han, Sang Kyung Seo, Jong Gwang Kim, Sang Kyun Sohn, Tae-In Park
Korean J Intern Med. 2014;29(6):785-792. Published online October 31, 2014
Background/Aims: This study investigated the expression of nuclear factor κB (NF-κB) and the chemokine receptor (CXCR4) in patients with diffuse large B-cell lymphoma (DLBCL) who received rituximab-based therapy.
Methods: Seventy patients with DLBCL and treated with rituximab-CHOP (R-CHO..
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A Case of Transition of Polycythemia Vera to Chronic Neutrophilic Leukemia
Seung Soon Lee, Joon Ho Moon, Jun Wook Ha, Young Kyung Lee, Jin Seok Ahn, Dae Young Zang, Hyo Jung Kim
Korean J Intern Med. 2004;19(4):285-288. Published online December 1, 2004
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Geriatric risk model for older patients with diffuse large B-cell lymphoma (GERIAD): a prospective multicenter cohort study
Ho-Young Yhim, Yong Park, Jeong-A Kim, Ho-Jin Shin, Young Rok Do, Joon Ho Moon, Min Kyoung Kim, Won Sik Lee, Dae Sik Kim, Myung-Won Lee, Yoon Seok Choi, Seong Hyun Jeong, Kyoung Ha Kim, Jinhang Kim, Chang-Hoon Lee, Ga-Young Song, Deok-Hwan Yang, Jae-Yong Kwak
Received June 19, 2023 Accepted November 27, 2023 Published online January 30, 2024
Background/Aims: Optimal risk stratification based on simplified geriatric assessment to predict treatment-related toxicity and survival needs to be clarified in older patients with diffuse large B-cell lymphoma (DLBCL).
Methods: This multicenter prospective cohort study enrolled newly diagnosed pat..
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