| Reviews |
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Gastroenterology
Newer treatments for advanced hepatocellular carcinoma
Myeong Jun Song, Si Hyun Bae
Korean J Intern Med. 2014;29(2):149-155. Published online February 27, 2014
Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. The only curative treatment modalities for HCC are surgery, percutaneous ablation, and liver transplantation. Unfortunately, the majority of patients have unresectable disease at diagnosis. Therefore, effective treatment opt..
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Current status of functional dyspepsia in Korea
Hyuk Lee, Hye-Kyung Jung, Kyu Chan Huh, Functional Dyspepsia Study Group in the Korean Society of Neurogastroenterology and Motility
Korean J Intern Med. 2014;29(2):156-165. Published online February 27, 2014
Dyspepsia refers to group of commonly occurring upper gastrointestinal symptoms. The majority of patients with dyspepsia suffer from functional (nonulcer) dyspepsia. Although there is a lack of epidemiological data from population-based or patient cohort studies in Korea, the current understanding o..
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| Editorials |
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Urokinase-type plasminogen activator receptor in IgA nephropathy
Shin-Young Ahn, Ho Jun Chin
Korean J Intern Med. 2014;29(2):166-169. Published online February 27, 2014
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Is ambient air pollution another risk factor of tuberculosis?
Jusang Kim
Korean J Intern Med. 2014;29(2):170-172. Published online February 27, 2014
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Can natural products serve as potential treatments for osteoarthritis?
Hyun-Sook Kim
Korean J Intern Med. 2014;29(2):173-175. Published online February 27, 2014
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| Original Articles |
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Nephrology
Urokinase, urokinase receptor, and plasminogen activator inhibitor-1 expression on podocytes in immunoglobulin A glomerulonephritis
Ji-Hye Lee, Mee-Hye Oh, Jae-Seok Park, Gyoung-Jae Na, Hye-Wook Gil, Jong-Oh Yang, Eun-Young Lee, Sae-Yong Hong
Korean J Intern Med. 2014;29(2):176-182. Published online February 27, 2014
Background/Aims: The purpose of this study was to investigate the expression of urokinase-type plasminogen activator (uPA), uPA receptor (uPAR), and plasminogen activator inhibitor (PAI)-1 on podocytes in immunoglobulin A (IgA) glomerulonephritis (GN).
Methods: Renal biopsy specimens from 52 IgA G..
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Pulmonology
Impact of outdoor air pollution on the incidence of tuberculosis in the Seoul metropolitan area, South Korea
Seung-sik Hwang, Sungchan Kang, Ji-Young Lee, Ji Sun Lee, Hee Jin Kim, Sung Koo Han, Jae-Joon Yim
Korean J Intern Med. 2014;29(2):183-190. Published online February 27, 2014
Background/Aims: Although indoor air pollution is a well-known risk factor for tuberculosis (TB), the possible link between outdoor air pollution and TB development has not been examined fully. We assessed the impact of outdoor air pollution on TB development in the Seoul metropolitan area, South Ko..
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Etc. - Orthopedic
Evaluation of the effect of D-002, a mixture of beeswax alcohols, on osteoarthritis symptoms
Roberto Puente, José Illnait, Rosa Mas, Daisy Carbajal, Sarahí Mendoza, Julio César Fernández, Meilis Mesa, Rafael Gámez, Pablo Reyes
Korean J Intern Med. 2014;29(2):191-202. Published online February 27, 2014
Background/Aims: Nonsteroidal anti-inflammatory drugs relieve osteoarthritis (OA) symptoms but cause adverse effects. D-002, a mixture of beeswax alcohols, is effective against experimental OA. A pilot study found that D-002 (50 mg/day) for 8 weeks improves OA symptoms. The aim of this study was to ..
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Cardiology
Effect of renin-angiotensin-system blockers on contrast-medium-induced acute kidney injury after coronary angiography
Ja-Jun Goo, Jae-Joon Kim, Ji-Hoon Kang, Kyoung-Nyoun Kim, Ki-Sup Byun, Mi-kyung Kim, Tae-Ik Kim
Korean J Intern Med. 2014;29(2):203-209. Published online February 27, 2014
Background/Aims: With the increasing incidence of cardiovascular disease, angiocardiography using contrast-enhancing media has become an essential diagnostic and therapeutic tool, despite the risk of contrast-medium-induced acute kidney injury (CIAKI). CIAKI may be exacerbated by renin-angiotensin-s..
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Efficacy and safety of antiplatelet-combination therapy after drug-eluting stent implantation
Yun-Kyeong Cho, Chang-Wook Nam, Hyoung-Seob Park, Hyuck-Jun Yoon, Hyungseop Kim, Seung-Ho Hur, Yoon-Nyun Kim, Jang-Hoon Lee, Dong-Heon Yang, Bong-Ryeol Lee, Byung-Chun Jung, Woong Kim, Jong-Seon Park, Jin-Bae Lee, Kee-Sik Kim, Kwon-Bae Kim
Korean J Intern Med. 2014;29(2):210-216. Published online February 27, 2014
Background/Aims: Combination single-pill therapy can improve cost-effectiveness in a typical medical therapy. However, there is a little evidence about the efficacy and tolerability of combination single-pill antiplatelet therapy after percutaneous coronary intervention (PCI) with drug-eluting stent..
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Endocrinology-metabolism
Changes in the clinical manifestations of primary aldosteronism
Sun Hwa Kim, Jae Hee Ahn, Ho Cheol Hong, Hae Yoon Choi, Yoon Jung Kim, Nam Hoon Kim, Hye Jin Yoo, Hee Young Kim, Ji A Seo, Nan Hee Kim, Sin Gon Kim, Kyung Mook Choi, Sei Hyun Baik, Dong Seop Choi
Korean J Intern Med. 2014;29(2):217-225. Published online February 27, 2014
Background/Aims: Primary aldosteronism (PA) is now widely recognized to have a higher prevalence than was once thought. In view of its increasing prevalence, we compared chronological changes in clinical manifestations of PA according to different times of diagnosis.
Methods: In total, 85 patients d..
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Nephrology
Whole blood versus serum ionized calcium concentrations in dialysis patients
Seok Hui Kang, Kyu Hyang Cho, Jong Won Park, Kyung Woo Yoon, Jun Young Do
Korean J Intern Med. 2014;29(2):226-230. Published online February 27, 2014
Background/Aims: The aim of this study is to measure the difference of ionized calcium between heparinized whole blood and serum.
Methods: We recruited 107 maintenance hemodialysis (HD) patients from our hospital HD unit. The clinical and laboratory data included ionized calcium in serum and in wh..
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| Case Reports |
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Dermatomyositis associated with hepatitis B virus-related hepatocellular carcinoma
Suh Yoon Yang, Bong Ki Cha, Gihyeon Kim, Hyun Woong Lee, Jae Gyu Kim, Sae Kyung Chang, Hyung Joon Kim
Korean J Intern Med. 2014;29(2):231-235. Published online February 27, 2014
Dermatomyositis is an idiopathic inflammatory myopathy with typical cutaneous manifestations. It has been proposed that dermatomyositis may be caused by autoimmune responses to viral infections. Previous studies have shown an association between dermatomyositis and malignant tumors such as ovarian c..
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Hypersensitivity myocarditis confirmed by cardiac magnetic resonance imaging and endomyocardial biopsy
Yumi Park, Sung Gyun Ahn, Anna Ko, Sang Ho Ra, Jaehwang Cha, Yong Gwan Jee, Ji Hyun Lee
Korean J Intern Med. 2014;29(2):236-240. Published online February 27, 2014
Myocarditis often occurs due to viral infections and postviral immune-mediated responses. Hypersensitivity myocarditis is a rare form of myocarditis. Numerous drugs can induce myocarditis, which is typically reversible after withdrawal of the causative agent. Here, we report a case of hypersensitivi..
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Isolated dilatation of the inferior vena cava
Jae-Joon Kim, Kyoung-Im Cho, Ji-Hoon Kang, Ja-Jun Goo, Kyoung-Nyoun Kim, Ja-Young Lee, Seong-Man Kim
Korean J Intern Med. 2014;29(2):241-245. Published online February 27, 2014
The diameter and collapsibility of the inferior vena cava (IVC) should be interpreted in consideration with other clinical and echocardiographic parameters before drawing definitive diagnostic conclusions. We report a case of a 46-year-old female with isolated IVC dilation and diminished inspiratory..
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Ifosfamide-induced Fanconi syndrome with diabetes insipidus
Ah Young Leem, Han Sang Kim, Byung Woo Yoo, Beo Deul Kang, Min Hwan Kim, Sun Young Rha, Hyo Song Kim
Korean J Intern Med. 2014;29(2):246-249. Published online February 27, 2014
Ifosfamide-induced Fanconi syndrome is a rare complication that typically occurs in young patients due to a cumulative dose of ifosfamide > 40–60 g/m2, a reduction in kidney mass, or concurrent cisplatin treatment. It is usually characterized by severe and fatal progression accompanied by type II ..
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| Letters to the editor |
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Chronic myeloid leukemia as a secondary malignancy after diffuse large B-cell lymphoma
Ha-young Lee, Kyung Hee Lee, Myung Soo Hyun, Min Kyoung Kim, Sung Ae Koh, Hee Soon Cho
Korean J Intern Med. 2014;29(2):250-252. Published online February 27, 2014
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Diagnosis of scrub typhus: introduction of the immunochromatographic test in Korea
Ki-Deok Lee, Chisook Moon, Won Sup Oh, Kyung Mok Sohn, Baek-Nam Kim
Korean J Intern Med. 2014;29(2):253-255. Published online February 27, 2014
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Successful treatment of enteropathy associated with common variable immunodeficiency
Seung Won Choi, Kwang Won Seo, Ji-Seon Oh, Jong Soo Lee, Hee Jeong Cha
Korean J Intern Med. 2014;29(2):256-258. Published online February 27, 2014
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Successful treatment with tacrolimus of refractory adult-onset Still’s disease
Masashi Ohe, Kenji Oku, Michihito Kono, Toshiyuki Bohgaki
Korean J Intern Med. 2014;29(2):259-261. Published online February 27, 2014
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| Images of interest |
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Sonographic evaluation of esophageal achalasia
Tae Hee Lee, Joo Young Cho
Korean J Intern Med. 2014;29(2):262-262. Published online February 27, 2014
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Ciprofloxacin: an uncommon drug reaction to a commonly used drug
Pedro Mendes-Bastos, Rodrigo Carvalho, Daniela Cunha, Jorge Cardoso
Korean J Intern Med. 2014;29(2):263-264. Published online February 27, 2014
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| Guideline |
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Guideline on the prevention and control of seasonal influenza in healthcare setting
Ji Hyeon Baek, Yu Bin Seo, Won Suk Choi, Sae Yoon Kee, Hye Won Jeong, Hee Young Lee, Byung Wook Eun, Eun Ju Choo, Jacob Lee, Sung Ran Kim, Young Keun Kim, Joon Young Song, Seong-Heon Wie, Jin-Soo Lee, Hee Jin Cheong, Woo Joo Kim, Transgovernmental Enterprise for Pandemic Influenza in Korea
Korean J Intern Med. 2014;29(2):265-280. Published online February 27, 2014
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