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| Case report |
Korean J Intern Med. 2006
;21(1):73-78.
A Patient with Primary Squamous Cell Carcinoma of the Thyroid Intermingled with Follicular Thyroid Carcinoma that Remains Alive more than 8 Years after Diagnosis
Tae Sik Jung, M.D.
Division of Endocrinology and Metabolism, Department of Medicine, Department of Pathology2 Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea |
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Primary squamous cell carcinoma of the thyroid is an extremely rare tumor with a highly aggressive clinical course.
We report here on a patient with primary squamous cell carcinoma of the thyroid who remains alive more than 8 years
after diagnosis. A 56-year-old man presented with a hoarse voice and a rapidly progressing mass on the right side of
the thyroid gland. The patient underwent a total thyroidectomy without neck lymph node dissection. Histopathologic findings
revealed primary squamous cell carcinoma combined with follicular carcinoma of the thyroid. The tumors metastasized to
the cervical lymph nodes, thoracic spine and lung. He underwent 5000 rads of adjuvant radiotherapy to the neck. TSH
suppressive therapy with L-thyroxine was administered alone rather than radioactive iodine therapy or chemotherapy. The
patient's clinical course has been remarkable over the first 7 years; he has remained stable except for a transient
paraplegia due to nerve compression. The patient underwent colectomy for the diagnosis of a colon cancer. Recent
evaluation has revealed a new lesion in the lung; this was diagnosed as metastatic follicular carcinoma originating from
the thyroid. High dose radioactive iodine therapy was administered, and he remains alive in stable condition.
Key Words : Squamous cell carcinoma, Adenocarcinoma, Follicular, Thyroid neoplasm |
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Keywords : Squamous cell carcinoma, Adenocarcinoma, Follicular, Thyroid neoplasm |
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