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Review
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Korean J Intern Med. 2026;41(4):563-571. Published online July 1, 2026.
DOI: https://doi.org/10.3904/kjim.2025.401
- Recent advances in the management of small bowel Crohn’s disease
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Kwangwoo Nam1, Hee Seok Moon2
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1Department of Gastroenterology, Dankook University Hospital, Dankook University College of Medicine, Cheonan, Korea
2Division of Gastroenterology, Department of Internal Medicine, Chungnam National University Hospital, Chungnam National University College of Medicine, Daejeon, Korea
- Corresponding author: Hee Seok Moon ,Tel: +82-42-280-7163, Email: mhs1357@cnuh.co.kr
- Received: November 18, 2025; Revised: February 5, 2026 Accepted: February 12, 2026.
- Abstract
- Crohn’s disease (CD) is a chronic inflammatory disorder of the bowel characterized by alternating periods of remission and relapse. Although CD can affect any part of the gastrointestinal tract, small bowel involvement is particularly common and generally considered a more challenging subtype than isolated colonic disease. Moreover, small bowel CD is frequently associated with complications such as strictures and fistulas, which may require invasive treatments including endoscopic or surgical intervention. The management of small bowel CD necessitates a nuanced approach that combines advanced diagnostic modalities with individualized medical and procedural strategies. Future research should prioritize the identification of predictive biomarkers, the development of precision therapeutics, and the improvement of long-term outcomes in this distinct disease phenotype.
Keywords :Crohn’s disease; Small bowel; Stricture; Personalized
