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ORIGINAL ARTICLES 2014 October 30
Long-term outcomes of balloon dilation versus botulinum toxin injection in patients with primary achalasia
1. In Korean patients with achalasia, the short-term symptom relief after intrasphincteric botulinum toxin injection and balloon dilation treatment are similar. 2. Ballon dilatation had a better long-term outcome than that of intrasphincteric Botox injection in the treatment of achalasia. 3. Independent factors predicting long-term remission included treatment type and the difference in the lower esophageal sphincter pressure. The symptom-free period was significantly longer if the difference in LESP was > 19 mmHg, suggesting the usefulness of manometric follow-up after treatment.
ORIGINAL ARTICLES 2014 October 30
The diagnostic utility of chest computed tomography scoring for the assessment of amiodarone-induced pulmonary toxicity
1. Computed tomography (CT) score is helpful in assessment and management of amiodarone-induced pulmonary toxicity (APT) for symptomatic long term amiodarone user. 2. Especially, high APT CT score may be related with pulmonary insufficiency and rapid progress of respiratory failure. 3. There was little evidence of new development or recurrence of APT after discontinuing amiodarone.
ORIGINAL ARTICLES 2014 October 30
Effects of intensive versus mild lipid lowering by statins in patients with ischemic congestive heart failure: Korean Pitavastatin Heart Failure (SAPHIRE) study
1. In heart failure patients with ischemic origin, statin treatment is required in order to prevent second ischemic attack. 2. However, ‘too much’ lowering of cholesterol might not be beneficial in heart failure patients especially in functional capacity recovery.
ORIGINAL ARTICLES 2014 October 30
The impact of high-flux dialysis on mortality rates in incident and prevalent hemodialysis patients
1. High-flux (HF) dialysis was associated with a decreased mortality rate in prevalent hemodialysis (HD) patients, but not in incident HD patients. 2. The use of HF dialysis membranes should be recommended for prevalent patients.
ORIGINAL ARTICLES 2014 September 30
Clinical significance of nuclear factor κB and chemokine receptor CXCR4 expression in patients with diffuse large B-cell lymphoma who received rituximab-based therapy
1. Diffuse large B-cell lymphoma (DLBCL) can be subdivided into several subtypes according to the immunochemical features. 2. Nuclear factor κB (NF-κB) and CXCR4 were coexpressed in 80% of the patients. 3. The expression of NF-κB and CXCR4 may not be an independent prognostic marker for DLBCL patients treated with rituximab-CHOP.
ORIGINAL ARTICLES 2014 October 30
Kinetics of T-cell-based assays on cerebrospinal fluid and peripheral blood mononuclear cells in patients with tuberculous meningitis
1. Serial peripheral blood mononuclear cell enzymelinked immunosorbent spot assays during the course of treatment were found to be ineffective for predicting clinical response in patients with tuberculous meningitis (TBM). 2. Increases in tuberculosis (TB)-specific interferon- gamma producing T-cell response on cerebrospinal fluid-mononuclear cells during the early phase of anti-TB therapy may be predictive of clinical failure in patients with TBM.
ORIGINAL ARTICLES 2014 October 30
Early effects of tumor necrosis factor inhibition on bone homeostasis after soluble tumor necrosis factor receptor use
1. Twelve weeks of etanercept treatment dramatically reduces systemic inflammation. 2. Levels of circulating bone metabolism markers—including c-telopeptide-1 and sclerostin—are elevated after etanercept treatment. 3. Short-term etanercept therapy appears to restore homeostasis in bone metabolism following chronic use of methotrexate and glucocorticoids.
ORIGINAL ARTICLES 2014 October 30
Complex repetitive discharge on electromyography as a risk factor for malignancy in idiopathic inflammatory myopathy
1. Patients with malignancies related to idiopathic inflammatory myopathy (IIM) had a higher incidence of complex repetitive discharge (CRD) on electromyography (p = 0.008) as well as dysphagia (p < 0.001) and the absence of interstitial lung disease (p = 0.034) versus those without malignancies. 2. Multivariate logistic regression analysis revealed that the CRD conferred an odds ratio of 25.99 (95% confidence interval, 1.27 to 531.86; p = 0.034) for malignancy. 3. A higher number of risk factors may be a warning sign for hidden malignancies in IIM, suggesting the need for a thorough evaluation for malignancies.
Volume29 No. 6
Current Issue
Volume 29(6); November 2014
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Reviews
Role of modern 3D echocardiography in valvular heart disease
Korean J Intern Med. 2014;29(6):685-702.   Published online 2014 October 30
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The scientific achievements of the decades in Korean Acute Myocardial Infarction Registry
Korean J Intern Med. 2014;29(6):703-712.   Published online 2014 October 30
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Recent advances in treatment of aplastic anemia
Korean J Intern Med. 2014;29(6):713-726.   Published online 2014 October 30
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Editorials
The long-term outcome of balloon dilation versus botulinum toxin injection in patients with primary achalasia
Korean J Intern Med. 2014;29(6):727-729.   Published online 2014 October 30
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Appropriate candidates for statin use in heart failure
Korean J Intern Med. 2014;29(6):730-734.   Published online 2014 October 30
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Changes in the epidemiology and burden of community-acquired pneumonia in Korea
Korean J Intern Med. 2014;29(6):735-737.   Published online 2014 October 30
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Original articles
Long-term outcomes of balloon dilation versus botulinum toxin injection in patients with primary achalasia
Korean J Intern Med. 2014;29(6):738-745.   Published online 2014 October 30
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The diagnostic utility of chest computed tomography scoring for the assessment of amiodarone-induced pulmonary toxicity
Korean J Intern Med. 2014;29(6):746-753.   Published online 2014 October 30
     PDF
Effects of intensive versus mild lipid lowering by statins in patients with ischemic congestive heart failure: Korean Pitavastatin Heart Failure (SAPHIRE) study
Korean J Intern Med. 2014;29(6):754-763.   Published online 2014 October 30
     PDF
Disease burden of pneumonia in Korean adults aged over 50 years stratified by age and underlying diseases
Korean J Intern Med. 2014;29(6):764-773.   Published online 2014 October 30
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The impact of high-flux dialysis on mortality rates in incident and prevalent hemodialysis patients
Korean J Intern Med. 2014;29(6):774-784.   Published online 2014 October 30
     PDF
Clinical significance of nuclear factor κB and chemokine receptor CXCR4 expression in patients with diffuse large B-cell lymphoma who received rituximab-based therapy
Korean J Intern Med. 2014;29(6):785-792.   Published online 2014 September 30
     PDF
Kinetics of T-cell-based assays on cerebrospinal fluid and peripheral blood mononuclear cells in patients with tuberculous meningitis
Korean J Intern Med. 2014;29(6):793-799.   Published online 2014 October 30
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Clinical features of elderly chronic urticaria
Korean J Intern Med. 2014;29(6):800-806.   Published online 2014 October 30
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Early effects of tumor necrosis factor inhibition on bone homeostasis after soluble tumor necrosis factor receptor use
Korean J Intern Med. 2014;29(6):807-813.   Published online 2014 October 30
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Complex repetitive discharge on electromyography as a risk factor for malignancy in idiopathic inflammatory myopathy
Korean J Intern Med. 2014;29(6):814-821.   Published online 2014 October 30
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Letters to the editor
Funtional significance of the intermediate lesion in a single coronary artery assessed by fractional flow reserve
Korean J Intern Med. 2014;29(6):822-824.   Published online 2014 October 30
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Graves’ disease presenting with acute renal infarction
Korean J Intern Med. 2014;29(6):825-826.   Published online 2014 October 30
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Persistent suboptimal molecular response in a patient with chronic myelogenous leukemia and Klinefelter syndrome
Korean J Intern Med. 2014;29(6):827-829.   Published online 2014 October 30
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Transformation into large-cell neuroendocrine carcinoma associated with acquired resistance to erlotinib in nonsmall cell lung cancer
Korean J Intern Med. 2014;29(6):830-833.   Published online 2014 October 30
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Parvimonas micra chest wall abscess following transthoracic lung needle biopsy
Korean J Intern Med. 2014;29(6):834-837.   Published online 2014 October 30
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Images of interest
Crystals in a patient with asymptomatic proteinuria
Korean J Intern Med. 2014;29(6):838-839.   Published online 2014 October 30
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Fibromuscular dysplasia: a cause of secondary hypertension
Korean J Intern Med. 2014;29(6):840-841.   Published online 2014 October 30
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