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Infectious diseases / Original Article
Cytokine profiles associated with persisting symptoms of post-acute sequelae of COVID-19
Ji-Soo Kwon, Euijin Chang, Hyeon Mu Jang, Ji Yeun Kim, Woori Kim, Ju Yeon Son, Junho Cha, Choi Young Jang, Seongman Bae, Jiwon Jung, Min Jae Kim, Yong Pil Chong, Sang-Oh Lee, Sang-Ho Choi, Yang Soo Kim, Sung-Han Kim
Korean J Intern Med. 2025;40(4):667-675. Published online July 1, 2025
Background/Aims: Post-acute sequelae of COVID-19 (PASC) are highly heterogeneous; therefore, the pathophysiological mechanisms for PASC remain unclear. In this study, we aimed to examine the immunologic aspects of various PASC symptoms.
Methods: We prospectively enrolled adults aged ≥ 18 years wh..
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Microbiology / Review
Counteracting the enzymatic activity of dipeptidylpeptidase 4 for potential therapeutic advantage, with an emphasis on cord blood transplantation
Hal E. Broxmeyer
Korean J Intern Med. 2013;28(6):639-645. Published online October 29, 2013
Dipeptidylpeptidase (DPP) 4, also known as CD26, is an enzyme present on the surface of a number of different cell types. It is also found within cells and as a soluble protein in body fluids. It can specifically truncate proteins at the penultimate N-terminus residue for some amino acids, such a..
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Original Article
Relation of Anti- to Pro-Inflammatory Cytokine Ratios with Acute Myocardial Infarction
Santanu Biswas, Pradip K. Ghoshal, Sankar C. Mandal, Nripendranath Mandal
Korean J Intern Med. 2010;25(1):44-50. Published online February 26, 2010
Background/AimsAcute myocardial infarction (AMI) is a leading cause of death. Inflammatory processes play an important role in atherosclerosis, which is intimately related to AMI. The aim of this study was to investigate the association between anti-inflammatory and pro-inflam..
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Original Article
The Effects of Methylene Blue on Hemodynamic Parameters and Cytokine Levels in Refractory Septic Shock
Byung-Kyu Park, Tae-Sun Shim, Chae-Man Lim, Sang-Do Lee, Woo-Sung Kim, Dong-Soon Kim, Won-Dong Kim, Younsuck Koh
Korean J Intern Med. 2005;20(2):123-128. Published online June 30, 2005
Background/AimsEndogenous nitric oxide (NO) induces the peripheral vasodilation via the activation of guanylate cyclase in patients with septic shock. The purpose of this study was to assess the acute effects of methylene blue (MB), which is an inhibitor of guanylate cyclase, ..
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