|
Pulmonology
Blockade of thymic stromal lymphopoietin and CRTH2 attenuates airway inflammation in a murine model of allergic asthma
Hea Yon Lee, Hwa Young Lee, Jung Hur, Hye Seon Kang, Joon Young Choi, Chin Kook Rhee, Ji Young Kang, Young Kyoon Kim, Sook Young Lee
Korean J Intern Med. 2020;35(3):619-629. Published online March 19, 2020
Background/Aims: Thymic stromal lymphopoietin (TSLP) is an epithelial cell-derived cytokine that plays a key role in Th2-mediated inflammation, both directly by promoting the proliferation of naïve CD4 Th2 cells, and indirectly by activating dendritic cells (DCs). TSLP-activated DCs induce the exp..
|
|
|
Combination of carboplatin and intermittent normobaric hyperoxia synergistically suppresses benzo[a]pyrene-induced lung cancer
Hea Yon Lee, In Kyoung Kim, Hye In Lee, Hwa Young Lee, Hye Seon Kang, Chang Dong Yeo, Hyun Hui Kang, Hwa Sik Moon, Sang Haak Lee
Korean J Intern Med. 2018;33(3):541-551. Published online December 15, 2017
Background/Aims: We explored the effects of intermittent normobaric hyperoxia alone or combined with chemotherapy on the growth, general morphology, oxidative stress, and apoptosis of benzo[a]pyrene (B[a]P)-induced lung tumors in mice.
Methods: Female A/J mice were given a single dose of B[a]P and ..
|
|
|
Clinical significance of positive Pneumocystis jirovecii polymerase chain reaction in non-human immunodeficiency virus immunocompromised patients in a real practice
Hea Yon Lee, Hye Seon Kang, Hwa Young Lee, Chin Kook Rhee, Sook Young Lee, Seok Chan Kim, Seung Joon Kim, Yeon Joon Park, Young Kyoon Kim, Ji Young Kang
Korean J Intern Med. 2017;32(3):478-485. Published online December 13, 2016
Background/Aims: Pneumocystis jirovecii polymerase chain reaction (PCR) can be helpful in diagnosing Pneumocystis pneumonia (PCP); however it has limitations. We evaluated the prevalence of positive P. jirovecii PCR from non-human immunodeficiency virus (HIV) immunocompromised p..
|
|
|
Effect of intranasal rosiglitazone on airway inflammation and remodeling in a murine model of chronic asthma
Hwa Young Lee, Chin Kook Rhee, Ji Young Kang, Chan Kwon Park, Sook Young Lee, Soon Suk Kwon, Young Kyoon Kim, Hyoung Kyu Yoon
Korean J Intern Med. 2016;31(1):89-97. Published online December 28, 2015
Background/Aims: Asthma is characterized by airway hyperresponsiveness, inflammation, and remodeling. Peroxisome proliferator-activated receptors have been reported to regulate inflammatory responses in many cells. In this study, we examined the effects of intranasal rosiglitazone on airway remodeli..
|
|
|
A Case of Post-Traumatic Coronary Occlusion
Hwa Young Lee, Young Man Ju, Man Ho Lee, Sang Jong Lee, Woon Ha Chang, Chin Woo Imm
Korean J Intern Med. 1991;6(1):33-38. Published online January 1, 1991
|
|
|
