Endocrinology-metabolism / Original Article
The effect of 5-aminoimidazole-4-carboxamideribonucleoside was mediated by p38 mitogen activated protein kinase signaling pathway in FRO thyroid cancer cells
Won Gu Kim, Hyun-Jeung Choi, Tae Yong Kim, Young Kee Shong, Won Bae Kim
Korean J Intern Med. 2014;29(4):474-481. Published online June 27, 2014
Background/Aims: 5′-Adenosine monophosphate (AMP)-activated protein kinase (AMPK) is a cellular energy sensor that monitors intracellular AMP/adenosine triphosphate (ATP) ratios and is a key regulator of the proliferation and survival of diverse malignant cell types. In the present study, we inves..
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