Nephrology / Original Article Arteriovenous fistulas are associated with superior outcomes in very elderly hemodialysis patients: a nationwide cohort study Hyung Duk Kim, Do Hyoung Kim, Hyangkyoung Kim, Hyung-Seok Lee, Seung Boo Yang, Seok Joon Shin, Hoon Suk Park; on behalf of the vascular access working group of the Korean Society of Dialysis Access Korean J Intern Med. 2026;41(1):152-162.   Published online January 1, 2026 DOI: https://doi.org/10.3904/kjim.2025.141                 Background/Aims: The optimal vascular access strategy for very elderly patients initiating hemodialysis (HD) remains unclear. Arteriovenous fistulas (AVFs) offer long-term benefits but may be limited due to vascular aging. This study evaluated vascular access outcomes in patients aged ≥ 80 years. ..

Nephrology / Review Clinical challenges and individualized approaches to dialysis therapy in older adults Sungmi Kim, Yu Ah Hong Korean J Intern Med. 2025;40(6):909-926.   Published online October 31, 2025 DOI: https://doi.org/10.3904/kjim.2025.147                      Global population aging has substantially increased in the number of older adults who undergo kidney replacement therapy (KRT). Age-related physiological changes and functional dependence in this population lead to the multifaceted clinical and ethical challenges associated with KRT. Geriatric syndr..

Nephrology / Review Shared decision-making for kidney replacement therapy: a comprehensive review and a proposed model Hyun Jung Shin, Seoyoung Choi, Sejoong Kim Korean J Intern Med. 2025;40(6):890-908.   Published online October 31, 2025 DOI: https://doi.org/10.3904/kjim.2025.019                 Shared decision-making (SDM) enables patients to actively engage in healthcare decisions by ensuring that treatment options align with their values and preferences. The use of SDM is increasingly recognized in the context of selecting kidney replacement therapy (KRT) for patients with chronic kidney..

Nephrology / Image of interest Leiomyosarcoma at popliteal vein presented as unilateral leg edema in a patient with kidney transplantation Sang Heon Song Korean J Intern Med. 2025;40(5):858-859.   Published online August 26, 2025 DOI: https://doi.org/10.3904/kjim.2025.097

Nephrology / Image of interest Findings suggestive of Fanconi syndrome and multiple myeloma Hwa-Young Lee, Sung Gyul Lim, Han Sang Lee, Won-Ae Lee, So Mi Kim Korean J Intern Med. 2025;40(5):856-857.   Published online July 17, 2025 DOI: https://doi.org/10.3904/kjim.2025.004

Nephrology / Original Article Association of kidney function and proteinuria with lower-extremity dysfunction in older Korean adults: a cross-sectional study Bongjo Kim, Eun-Bin Lim, Young Sang Lyu, Minkook Son, Youngmin Yoon Korean J Intern Med. 2025;40(5):823-834.   Published online July 25, 2025 DOI: https://doi.org/10.3904/kjim.2025.088                      Background/Aims: Chronic kidney disease (CKD) is associated with complications that affect physical function and mobility. This study investigated the associations between kidney function, proteinuria, and lower-extremity dysfunction. Methods: Data were obtained from the Korean National Health Insu..

Nephrology / Review Clinical benefits and future directions of medium cut-off membranes in hemodialysis: a comprehensive review Hyo Jin Kim, Sang Heon Song Korean J Intern Med. 2025;40(4):557-570.   Published online July 1, 2025 DOI: https://doi.org/10.3904/kjim.2025.049              Web of Science 1    Crossref 2                 Medium cut-off (MCO) membranes have emerged as a promising innovation in hemodialysis (HD), offering enhanced clearance of large middle-molecules of uremic toxins compared to traditional HD membranes, while maintaining minimal loss of albumin. The introduction of MCO membranes represents a significa..

Nephrology / Original Article Impaired aldosterone response to potassium and hyperkalemia in patients receiving a renin-angiotensin-aldosterone system inhibitor Miyeon Kim, Hwa Young Lee, Hyunwoo Kim Korean J Intern Med. 2025;40(3):468-481.   Published online April 30, 2025 DOI: https://doi.org/10.3904/kjim.2024.160                 Background/Aims: Angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs) are associated with the development of hyperkalemia. We evaluated the relationship between the serum aldosterone-to-potassium ratio (APR) and the risk of developing hyperkalemia in patients ..

Nephrology / Image of interest Renal recovery from membranous lupus nephritis with antineutrophil cytoplasmic antibody-associated glomerulonephritis with belimumab Wenfeng Wang, Zishan Lin, Bingjing Jiang, Yanfang Xu Korean J Intern Med. 2025;40(2):339-340.   Published online February 25, 2025 DOI: https://doi.org/10.3904/kjim.2024.278

Nephrology / Original Article Predicting renal function using fundus photography: role of confounders Hyun-Woong Park, Hae Ri Kim, Ki Yup Nam, Bum Jun Kim, Taeseen Kang Korean J Intern Med. 2025;40(2):310-320.   Published online March 1, 2025 DOI: https://doi.org/10.3904/kjim.2024.076              Crossref 1                 Background/Aims: The kidneys and retina are highly vascularized organs that frequently exhibit shared pathologies, with nephropathy often associated with retinopathy. Previous studies have successfully predicted estimated glomerular filtration rates (eGFRs) using fundus photographs. We evaluated the..

Nephrology / Review Glial cell line-derived neurotrophic factor and its role in attenuating renal fibrosis: a review Yousuf Abdulkarim Waheed, Wokuheleza Buberwa, Dong Sun Korean J Intern Med. 2025;40(2):219-229.   Published online December 13, 2023 DOI: https://doi.org/10.3904/kjim.2023.246                 Chronic kidney disease is estimated to affect approximately 10 to 15% of the Chinese population. Renal fibrosis is characterized by progressive extracellular matrix deposition in the kidney parenchyma with eventual tissue scarring and inevitable deterioration of renal function. Vascular rarefaction,..

Nephrology / Original Article Kidney replacement therapy trends in end-stage kidney disease patients in South Korea during the COVID-19 pandemic Ah-Young Kim, Min-Jeong Lee, Heejung Choi, Hankil Lee, Inwhee Park Korean J Intern Med. 2024;39(6):967-978.   Published online October 24, 2024 DOI: https://doi.org/10.3904/kjim.2024.052              Web of Science 3    Crossref 5                 Background/Aims: The corona virus disease 2019 posed a major risk for end-stage kidney disease (ESKD) cases. Our study aimed to assess changes in kidney replacement therapy (KRT) trends and healthcare access for these patients during the pandemic. Methods: We retrospectively analyzed nationwide dat..

Nephrology / Review Steps to understanding diabetes kidney disease: a focus on metabolomics Hyo Jin Kim, Sang Heon Song Korean J Intern Med. 2024;39(6):898-905.   Published online October 22, 2024 DOI: https://doi.org/10.3904/kjim.2024.111              Web of Science 2    Crossref 2                 Diabetic nephropathy (DN), a leading cause of chronic kidney disease and end-stage kidney disease (ESKD), poses global health challenges given its increasing prevalence. DN increases the risk of mortality and cardiovascular events. Early identification and appropriate DN management are crucial. Howe..

Nephrology / Review Machine learning approaches toward an understanding of acute kidney injury: current trends and future directions Inyong Jeong, Nam-Jun Cho, Se-Jin Ahn, Hwamin Lee, Hyo-Wook Gil Korean J Intern Med. 2024;39(6):882-897.   Published online October 29, 2024 DOI: https://doi.org/10.3904/kjim.2024.098              Web of Science 2    Crossref 2                      Acute kidney injury (AKI) is a significant health challenge associated with adverse patient outcomes and substantial economic burdens. Many authors have sought to prevent and predict AKI. Here, we comprehensively review recent advances in the use of artificial intelligence (AI) to predict AKI, and t..

Nephrology / Review Kidney transplantation in the elderly Byung Hwa Park, Song Yi Kil, Ye Na Kim, Ho Sik Shin, Yeonsoon Jung, Hark Rim Korean J Intern Med. 2024;39(6):875-881.   Published online October 24, 2024 DOI: https://doi.org/10.3904/kjim.2024.089              Web of Science 1    Crossref 1                 Interest in kidney transplant studies in the elderly population is increasing as more research has been conducted on the immune system. With this review, we hope to encourage the need for research on kidney transplantation in the elderly.

Nephrology / Editorial Impact of COVID-19 on end-stage kidney disease incidence and clinical practice Hayne Cho Park, Young-Ki Lee Korean J Intern Med. 2024;39(6):872-874.   Published online November 1, 2024 DOI: https://doi.org/10.3904/kjim.2024.350

Nephrology / Original Article Obesity is associated with incident chronic kidney disease in individuals with normal renal function Su Hyun Song, Tae Ryom Oh, Sang Heon Suh, Hong Sang Choi, Chang Seong Kim, Seong Kwon Ma, Soo Wan Kim, Eun Hui Bae Korean J Intern Med. 2024;39(5):813-822.   Published online August 13, 2024 DOI: https://doi.org/10.3904/kjim.2023.491              Web of Science 4    Crossref 3                      Background/Aims: Obesity has known to be a modifiable risk factor associated with worse outcomes in chronic kidney disease (CKD), but few studies have examined the impact of obesity on CKD incidence in the general population. The purpose of this study was to investigate the role of body mass index (..

Nephrology / Editorial Obesity and chronic kidney disease, an important piece in the puzzle of Cardiovascular–Kidney– Metabolic syndrome Young Youl Hyun Korean J Intern Med. 2024;39(5):700-701.   Published online August 30, 2024 DOI: https://doi.org/10.3904/kjim.2024.273              Web of Science 2    Crossref 2

Nephrology / Image of interest Primary peritoneal carcinoma presented with abdominal pain in patient with kidney transplantation Eunmi Jo, Sang Heon Song Korean J Intern Med. 2024;39(4):693-694.   Published online April 29, 2024 DOI: https://doi.org/10.3904/kjim.2023.254              Crossref 1

Nephrology / Original Article A retrospective study on the efficacy of Roxadustat in peritoneal dialysis patients with erythropoietin hyporesponsiveness Jie Liu, Shuang Li, Fan Yang, Tianyu Li, Rui Li, Yousuf Waheed, Chen Meng, Shulin Li, Kun Liu, Yanshan Tong, Haisheng Xu, Chuankuo Tian, Xinglei Zhou Korean J Intern Med. 2024;39(3):488-500.   Published online April 23, 2024 DOI: https://doi.org/10.3904/kjim.2023.520              Web of Science 1    Crossref 1                 Background/Aims: Roxadustat, an oral medication for treating renal anemia, is a hypoxia-inducible factor prolyl hydroxylase inhibitor used for regulating iron metabolism and promoting erythropoiesis. To investigate the efficacy and safety of roxadustat in patients undergoing peritoneal dialysis (PD)..