Pulmonology / Original Article
Efficacy and safety of HL-301 compared with erdosteine in acute bronchitis: a randomized, double-blind, non-inferiority trial
Ji-Yong Moon, Joon Young Choi, Youlim Kim, Hye Jung Park, Yong Bum Park, Seong Yong Lim, Kyung Hoon Min, Deog Kyeom Kim, Chin Kook Rhee, Seung Won Ra, Chang Youl Lee, Yong Il Hwang, Kwang Ha Yoo
Korean J Intern Med. 2025;40(5):790-800. Published online August 26, 2025
Background/Aims: This study evaluated the non-inferiority of HL-301 to erdosteine in terms of symptom relief and the anti- inflammatory effects in acute bronchitis patients not treated with antibiotics.
Methods: In a double-blind, non-inferiority trial, patients were randomized 1:1 to receive eithe..
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Pulmonology / Original Article
Korean physician prescription patterns for home oxygen therapy in chronic obstructive pulmonary disease patients
Youlim Kim, Hwan Il Kim, Ji Young Park, Ji Young Hong, Joo-Hee Kim, Kyung Hoon Min, Chin Kook Rhee, Sunghoon Park, Chang Youl Lee, Seong Yong Lim, Seung Hun Jang, Yong Il Hwang
Korean J Intern Med. 2022;37(1):119-126. Published online August 20, 2021
Background/Aims: Hypoxemia in chronic obstructive pulmonary disease (COPD) leads to reduced ability to exercise, decreased quality of life, and, eventually, increased mortality. Home oxygen therapy in patients with severe COPD reduces distress symptoms and mortality rates. However, there have been fe..
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Pulmonology / Original Article
Cut-off value of FEV1/FEV6 to determine airflow limitation using handheld spirometry in subjects with risk of chronic obstructive pulmonary disease
Yong Il Hwang, Youlim Kim, Chin Kook Rhee, Deog Kyeom Kim, Yong Bum Park, Kwang Ha Yoo, Ki-Suck Jung, Chang Youl Lee
Korean J Intern Med. 2021;36(3):629-635. Published online June 24, 2020
Background/Aims: Postbronchodilator forced expiratory volume in 1 second (FEV1)/forced vital capacity (FVC) less than 0.7 using spirometry is the golden standard to diagnose airf low limitation of chronic obstructive pulmonary disease (COPD). Recently, measuring FEV6 has been s..
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