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Gastroenterology / Original Article
Population-specific rare variants influence age at diagnosis in Korean inflammatory bowel disease
Mina Cho, DongHwan Shin, Jongwook Yu, Jae Hee Cheon, Ju Han Kim
Korean J Intern Med. 2026;41(5):847-857. Published online September 1, 2026
Background/Aims: Inflammatory bowel disease (IBD), which includes Crohn's disease (CD) and ulcerative colitis (UC), is increasing in East Asia. Most known susceptibility loci, identified primarily in Europeans, remain insufficient to explain clinical heterogeneity in Asians. We performed whole-exome..
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Gastroenterology / Review
Recent advances in the management of small bowel Crohn’s disease
Kwangwoo Nam, Hee Seok Moon
Korean J Intern Med. 2026;41(4):563-571. Published online July 1, 2026
Crohn’s disease (CD) is a chronic inflammatory disorder of the bowel characterized by alternating periods of remission and relapse. Although CD can affect any part of the gastrointestinal tract, small bowel involvement is particularly common and generally considered a more challenging subtype than..
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Gastroenterology / Original Article
Prevalence of viral hepatitis A and C in patients with inflammatory bowel disease: a nationwide population-based study in South Korea
Jin Hwa Park, Sang Hyoung Park, Sang Pyo Lee, Kang Nyeong Lee, Hang Lak Lee, Oh Young Lee, Soorack Ryu, Junwon Go
Korean J Intern Med. 2026;41(1):95-106. Published online January 1, 2026
Background/Aims: We investigated whether patients with inflammatory bowel disease (IBD) in Korea have an increased risk of hepatitis A virus (HAV) and hepatitis C virus (HCV) infections and sought to identify the risk factors for these infections.
Methods: We performed a nationwide population-based..
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Gastroenterology / Original Article
Primary surgery versus pharmacotherapy for newly diagnosed ileocecal Crohn’s disease: a hospital-based cohort study
Yehyun Park, Soo Jung Park, Tae Il Kim, Won Ho Kim, Jae Hee Cheon
Korean J Intern Med. 2024;39(5):759-769. Published online June 24, 2024
Background/Aims: Limited knowledge exists regarding the optimal timing and relative advantages of primary surgery compared to medical treatment in ileocecal Crohn’s disease (CD). This study aimed to compare long-term outcomes between medication-based treatment versus surgery in newly diagnosed ile..
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Gastroenterology / Original Article
Self-screening questionnaire for perianal fistulizing disease in patients with Crohn’s disease
O Seong Kweon, Ben Kang, Yoo Jin Lee, Eun Soo Kim, Sung Kook Kim, Hyun Seok Lee, Yun Jin Chung, Kyeong Ok Kim, Byung Ik Jang; on behalf of Crohn’s Colitis Association in Daegu-Gyeongbuk (CCAiD)
Korean J Intern Med. 2024;39(3):430-438. Published online April 5, 2024
Background/Aims: A poor prognostic factor for Crohn’s disease (CD) includes perianal fistulizing disease, including perianal fistula and/or perianal abscess. Currently, a tool to assess perianal symptoms in patients with CD remains nonexistent. This study aimed to develop a perianal fistulizing di..
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