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Rheumatology / Image of interest
Relapsing polychondritis presenting with intractable chronic cough, acute visual disturbance, and hearing loss
Hyunje Kim, Eunjung Kong
Korean J Intern Med. 2026;41(2):369-371. Published online March 1, 2026
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Cardiology / Image of interest
Too much synchrony? Left bundle branch area pacing-induced systolic anterior motion and left ventricular outflow tract obstruction managed by intentional atrioventricular dyssynchrony
Hyung Ki Jeong, Sung Soo Kim, Hyun Kuk Kim, Young Jae Ki, Dong Hyun Choi, Keun Ho Park
Korean J Intern Med. 2026;41(2):367-368. Published online March 1, 2026
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Hospital medicine / Original Article
Global burden of adverse effects of medical treatment from 1990 to 2021: a Global Burden of Disease Study 2021
GBD 2021 AEMT Collaborators
Korean J Intern Med. 2026;41(2):350-366. Published online March 1, 2026
Background/Aims: This study aims to evaluate the global burden of adverse effects of medical treatment (AEMT) using data from the Global Burden of Disease Study (GBD) 2021.
Methods: Data were extracted from the GBD 2021, covering 204 countries/territories from 1990 to 2021. AEMT was defined using I..
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Rheumatology / Original Article
Cross-cultural adaptation and preliminary validation of the Korean version of the Psoriatic Arthritis Impact of Disease-12 questionnaire
Bon San Koo, Jung Gon Kim, Bo Young Yoon, Ji-Hyoun Kang, Sung-Eun Choi, Sooin Jung, Seyeong Kim, Tae-Jong Kim
Korean J Intern Med. 2026;41(2):341-349. Published online March 1, 2026
Background/Aims: The Psoriatic Arthritis Impact of Disease (PsAID-12) questionnaire was developed to measure quality of life and disease impact in patients with psoriatic arthritis (PsA). We aimed to translate the English PsAID-12 into Korean and to evaluate its reliability and validity.
Methods: T..
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Allergy / Original Article
Drug hypersensitivity leading to emergency department visit: a comprehensive analysis of clinical features and management
Soo Jie Chung, Na Young Kim, So Jeong Kim, Junghyun Kim, Hang A Park, Jeong-Hee Choi
Korean J Intern Med. 2026;41(2):328-340. Published online March 1, 2026
Background/Aims: Drug hypersensitivity reactions (DHRs) are unpredictable adverse drug reactions that can present with varied clinical manifestations, including anaphylaxis. However, data on DHRs initially diagnosed in the emergency department (ED) and subsequently confirmed by allergy specialists r..
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Infectious diseases / Original Article
Hemodialysis vascular access infections: epidemiology and risk factors for treatment failure
Shi Nae Yu, Eunjung Lee, Se Yoon Park, Oh-Hyun Cho, Sangchul Yun, Tark Kim, Min Seo Kang, Yae Jee Baek, Jongtak Jung, Tae Hyong Kim
Korean J Intern Med. 2026;41(2):317-327. Published online March 1, 2026
Background/Aims: Infection remains the second leading cause of mortality in patients with end-stage renal disease (ESRD). Despite the direct relationship between hemodialysis vascular access-related infections (HD-VARI) and both prognosis and mortality in ESRD patients, there is a paucity of researc..
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Hemato-oncology / Original Article
High diffuse bone marrow uptake in 18F-FDG PET/CT may reflect the diverse mutational characteristics of multiple myeloma
Hee Jeong Cho, Donghyeon Lee, Tan Minh Le, Hong Duc Thi Nguyen, Juhyung Kim, Jung Min Lee, Dong Won Baek, Ha-Jeong Kim, Hyung Soo Han, Sang Kyun Sohn, Chae Moon Hong, Joon Ho Moon
Korean J Intern Med. 2026;41(2):307-316. Published online March 1, 2026
Background/Aims: To explore the biological implications of positron emission tomography/computed tomography (PET/CT) findings in multiple myeloma (MM), we investigated the mutational characteristics relevant to PET/CT findings using targeted DNA sequencing.
Methods: Fourteen newly diagnosed patient..
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Hemato-oncology / Original Article
Real-world use of polatuzumab vedotin combined with bendamustine and rituximab for patients with relapsed or refractory large B-cell lymphoma
Changgon Kim, Sang Eun Yoon, Hyun-Young Kim, Duck Cho, Junhun Cho, Won Seog Kim, Seok Jin Kim
Korean J Intern Med. 2026;41(2):296-306. Published online March 1, 2026
Background/Aims: Polatuzumab vedotin combined with bendamustine and rituximab (Pola-BR) is a treatment option for relapsed/refractory diffuse large B-cell lymphoma (R/R DLBCL), particularly as bridging therapy before chimeric antigen receptor (CAR) T-cell infusion. However, real-world data regarding..
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Endocrinology-metabolism / Original Article
Risk of atrial fibrillation in patients with differentiated thyroid cancer: a nationwide population-based analysis
Jung Heo, Seo Young Sohn, Yun Jin Kim, Sung Woo Cho
Korean J Intern Med. 2026;41(2):286-295. Published online March 1, 2026
Background/Aims: Thyroid hormone suppression therapy (THST) is widely used for long-term management of differentiated thyroid cancer (DTC). However, studies have suggested that THST may increase the risk of atrial fibrillation (AF) in patients with DTC. We aimed to evaluate whether the risk of AF in..
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Endocrinology-metabolism / Original Article
Development of Simple Assessment tool for predict imminent risk of Fracture in Elderly women
So Young Park, Sujin Kwon, Kyoung Jin Kim, Seong Hee Ahn, Ha Young Kim, Kyoung Min Kim; the Epidemiology Committee of the Korean Society of Bone Metabolism
Korean J Intern Med. 2026;41(2):277-285. Published online March 1, 2026
Background/Aims: Previously developed fracture risk prediction models primarily estimate long-term risk and are limited in their ability to predict imminent fractures. We developed a simplified and practical model to predict the short-term fracture risk (1- to 3-year risk) in elderly Korean women.
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Gastroenterology / Original Article
The effect of HFE gene mutation and iron overload on sustained virological response in Egyptian chronic hepatitis C patients treated with daclatasvir and sofosbuvir
Emad M. Kodsi, Hisham Ismail, Randa Issa, Ahmed Elshaarawy, Moustafa A. Sakr, Eman L. Shehata, Emad R Issak
Korean J Intern Med. 2026;41(2):265-276. Published online March 1, 2026
Background/Aims: This matched case-control study investigated the impact of HFE gene mutations on sustained virological response (SVR) in Egyptian patients with chronic hepatitis C (CHC) treated with daclatasvir and sofosbuvir.
Methods: A total of 150 CHC patients were enrolled (75 responders and 7..
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Gastroenterology / Original Article
Clinical features of NAAT-positive, toxin-negative Clostridioides difficile infections in South Korea
In Hyoung Choi, Chang Kyo Oh, Young Wook Cho, Young-Seok Cho
Korean J Intern Med. 2026;41(2):255-264. Published online March 1, 2026
Background/Aims: The clinical characteristics of Clostridioides difficile infection (CDI) in patients within the Asia-Pacific region who test positive on the nucleic acid amplification test (NAAT) and negative on the toxin enzyme immunoassay (EIA, hereafter referred to as “Toxin”) are uncle..
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Infectious diseases / Review
Updates on epidemiology and diagnostic tests of syphilis in South Korea
Dong Youn Kim, Ki-Ho Park
Korean J Intern Med. 2026;41(2):242-254. Published online March 1, 2026
Syphilis is a sexually transmitted disease caused by the spirochete Treponema pallidum. Recently, there has been a global resurgence of syphilis cases. In South Korea, the reported rate of syphilis steadily increased from 1.93 per 100,000 individuals in 2011 to 3.41 per 100,000 individuals in 2019. ..
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Hemato-oncology / Review
Assessment tools for peripheral neuropathy in multiple myeloma
Sung-Soo Park, Kunye Kwak, Seol-Hee Baek, Changgon Kim, Yoon Seok Choi, Yong Park, Byung Soo Kim, Jin Seok Kim, Chang-Ki Min, Ka-Won Kang
Korean J Intern Med. 2026;41(2):230-241. Published online March 1, 2026
Advances in treating multiple myeloma (MM) have improved survival, shifting the management focus toward quality of life. Peripheral neuropathy (PN) is a common treatment-related toxicity that significantly impairs quality of life. However, standardized assessment methods for PN in patients with MM a..
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Endocrinology-metabolism / Review
From bench to bedside: adipose tissue fibrosis in obesity, anti-diabetic therapies, and bariatric surgery
Mihye Seo, Kyoil Suh, Hyeong Kyu Park, Kae Won Cho
Korean J Intern Med. 2026;41(2):210-229. Published online December 23, 2025
This review provides a comprehensive examination of the recent research findings concerning the pathophysiology and clinical implications of adipose tissue fibrosis in obesity and metabolic diseases. Recent large-scale studies, including a longitudinal study spanning 24 years (Swedish Obese Subjects..
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Cardiology / Review
Pulsed field ablation: focused on atrial fibrillation ablation
Hong-Ju Kim, Chan-Hee Lee
Korean J Intern Med. 2026;41(2):197-209. Published online December 4, 2025
Atrial fibrillation (AF) is the most common sustained tachyarrhythmia and its increasing prevalence has resulted in a growing healthcare burden. Catheter ablation is indicated for patients with AF who are either refractory or intolerant to antiarrhythmic drugs or who exhibit decreased left ventricul..
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Gastroenterology / Review
The epidemiology of inflammatory bowel disease: exploring the impacts of environmental factors
Jihye Park, Jae Hee Cheon
Korean J Intern Med. 2026;41(2):186-196. Published online December 4, 2025
Inflammatory bowel diseases (IBD), such as ulcerative colitis and Crohn's disease, are distinct chronic immune-mediated intestinal inflammatory disorders. The pathogenesis of IBD is complex and involves a combination of genetic and environmental factors, the gut microbiome, and the host immune syste..
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Cardiology / Image of interest
Percutaneous retrieval of a trapped intravascular ultrasonography catheter within an implanted stent: failure and success
Daeung Ohn, Yeon-Jik Choi, Junghoon Lee, Suk-Min Seo
Korean J Intern Med. 2026;41(1):178-180. Published online December 4, 2025
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