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Pulmonology / Original Article
Comparison of clinical utility between diaphragm excursion and thickening change using ultrasonography to predict extubation success
[corrected-article]
Jung-Wan Yoo, Seung Jun Lee, Jong Deog Lee, Ho Cheol Kim
Korean J Intern Med. 2018;33(2):331-339. Published online October 19, 2017
Background/Aims: Both diaphragmatic excursion and change in muscle thickening are measured using ultrasonography (US) to assess diaphragm function and mechanical ventilation weaning outcomes. However, which parameter can better predict successful extubation remains to be determined. The aim of this ..
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Cardiology / Original Article
Predictors of acute myocarditis in complicated scrub typhus: an endemic province in the Republic of Korea
Jung Yeon Chin, Ki-Woon Kang, Kyung Min Moon, Jongwoo Kim, Yu Jeong Choi
Korean J Intern Med. 2018;33(2):323-330. Published online February 23, 2017
Background/Aims: Scrub typhus is known as a self-limited infectious disease. Cardiac complication is uncommon and usually not life-threatening. Until now, few cases of fulminant myocarditis by scrub typhus have been reported. So, we investigated incidence and predictors of acute myocarditis in sever..
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Cardiology / Original Article
Correlation between NADPH oxidase-mediated oxidative stress and dysfunction of endothelial progenitor cell in hyperlipidemic patients
Ting-Bo Li, Yin-Zhuang Zhang, Wei-Qi Liu, Jie-Jie Zhang, Jun Peng, Xiu-Ju Luo, Qi-Lin Ma
Korean J Intern Med. 2018;33(2):313-322. Published online September 13, 2017
Background/Aims: NADPH (nicotinamide adenine dinucleotide phosphate) oxidase (NOX)-mediated oxidative stress plays a key role in promotion of oxidative injury in the cardiovascular system. The aim of this study is to evaluate the status of NOX in endothelial progenitor cells (EPCs) of hyperlipidemic..
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Gastroenterology / Original Article
Analysis of computed tomographic findings according to gastroesophageal flap valve grade
Hye Kyung Jeon, Gwang Ha Kim, Nam Kyung Lee, Suk Kim, Bong Eun Lee, Geun Am Song
Korean J Intern Med. 2018;33(2):295-303. Published online December 12, 2016
Background/Aims: The gastroesophageal junction is an important barrier against gastroesophageal ref lux. Endoscopic grading of gastroesophageal f lap valve is simple, reproducible, and may predict reflux activity. We investigated the correlation between gastroesophageal flap valve grade and the gast..
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Rheumatology / Review
New insights into the role of renal resident cells in the pathogenesis of lupus nephritis
Seung-Ki Kwok, George C. Tsokos
Korean J Intern Med. 2018;33(2):284-289. Published online January 12, 2018
Systemic lupus erythematosus (SLE), an autoimmune disease of unknown etiology, is characterized by the production of autoantibodies and end-organ damage. Lupus nephritis affects up to 70% of patients with SLE and is the most critical predictor of morbidity and mortality. The immunopathogenesis of SL..
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Letter to the editor
Intracranial relapse as a solitary mass of ocular adnexal lymphoma of the mucosa-associated lymphoid tissue type
Jung-Ho Kim, Young-Woo Jeon, Byung-Ock Choi, Gyeongsin Park, Yong-Kil Hong, Suk-Woo Yang, Seok-Goo Cho
Korean J Intern Med. 2018;33(1):224-227. Published online September 7, 2016
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Letter to the editor
A novel neurofibromatosis type 1 (NF1) mutation in a patient with NF1 and pheochromocytoma
Yoorim Seo, Yeonjeong Jeong, Dong Yoon Kim, Kyueun Choi, Eun Sook Kim, Sung Dae Moon, Je Ho Han
Korean J Intern Med. 2018;33(1):214-217. Published online November 29, 2017
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Nephrology / Original Article
Long-term prognosis of end-stage renal disease patients with normal myocardial perfusion as determined by single photon emission computed tomography
Gun Ha Park, Jae Won Song, Chang Min Lee, Young Rim Song, Sung Gyun Kim, Hyung Jik Kim, Jwa Kyung Kim
Korean J Intern Med. 2018;33(1):148-156. Published online November 22, 2016
Background/Aims: Normal myocardial perfusion is closely associated with very low rates of cardiac events and better long-term outcomes; however, little is known about its prognostic value in patients with end-stage renal disease (ESRD).
Methods: A total of 286 incident patients underwent baseline c..
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Gastroenterology / Review
Present status and perspectives of endosonography 2017 in gastroenterology
Michael Hocke, Barbara Braden, Christian Jenssen, Christoph F. Dietrich
Korean J Intern Med. 2018;33(1):36-63. Published online November 23, 2017
Endoscopic ultrasound has become an essential tool in modern gastroenterology and abdominal surgery. Compared with all other endoscopic methods, it has the most potential for innovation and its future looks bright. Thus, we compiled this summary of established and novel applications of endoscopic ul..
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Gastroenterology / Review
Updated treatment strategies for intestinal Behçet’s disease
Yong Eun Park, Jae Hee Cheon
Korean J Intern Med. 2018;33(1):1-19. Published online December 8, 2017
Behçet’s disease (BD) is a chronic, idiopathic, relapsing immune-mediated disease involving multiple organs, and is characterized by recurrent oral and genital ulcers, ocular disease, gastrointestinal ulcers, vascular diseases, and skin lesions. In particular, gastrointestinal involvement in BD i..
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Letter to the editor
Wernicke encephalopathy as initial presentation of lymphoma
Ju Hyun Seo, Ju Hee Kim, Der Sheng Sun, Hye Sung Won, Jeong Wook Park, Yoon Ho Ko
Korean J Intern Med. 2017;32(6):1112-1114. Published online January 25, 2016
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Rheumatology / Original Article
The role of 18F-fluorodeoxyglucose positron emission tomography in the assessment of disease activity of adult-onset Still’s disease
Young-Sil An, Chang-Hee Suh, Ju-Yang Jung, Hundo Cho, Hyoun-Ah Kim
Korean J Intern Med. 2017;32(6):1082-1089. Published online December 7, 2016
Background/Aims: 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) has been suggested as a reliable imaging technique for monitoring of disease activity in patients with adult-onset Still’s disease (AOSD). Therefore, we investigated the ..
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Infectious diseases / Original Article
Diagnostic role of mean platelet volume and neutrophil to lymphocyte ratio in childhood brucellosis
Şefika Elmas Bozdemir, Yasemin Ay Altıntop, Salih Uytun, Humeyra Aslaner, Yasemin Altuner Torun
Korean J Intern Med. 2017;32(6):1075-1081. Published online December 14, 2016
Background/Aims: Brucellosis patients present various non-specific clinical symptoms, such as fever, fatigue, sweating, joint pain, arthritis, myalgia, and headache. Based on the nonspecifity of its clinical signs and symtoms, we decided to evaluate whether mean platelet volume (MPV) , neutrophil to..
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Endocrinology-metabolism / Original Article
p22phox C242T gene polymorphism and overt diabetic nephropathy: a meta-analysis of 1,452 participants
Yan-yan Li, Ge Gong, Hong-yu Geng, Yun Qian
Korean J Intern Med. 2017;32(6):1045-1052. Published online December 8, 2016
Background/Aims: The p22phox C242T gene polymorphism (rs4673) may be linked to an increased susceptibility for overt diabetic nephropathy (ODN), but the study results are still inconclusive.
Methods: To explore the relationship between p22phox C242T gene polymorphism and ODN, the curr..
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Pulmonology / Original Article
Epidemiological trend of pulmonary thromboembolism at a tertiary hospital in Korea
Tae Yun Park, Jae-Woo Jung, Jae Chol Choi, Jong Wook Shin, Jae Yeol Kim, Byoung Whui Choi, In Won Park
Korean J Intern Med. 2017;32(6):1037-1044. Published online March 13, 2017
Background/Aims: Despite increasing interest in pulmonary thromboembolism (PTE), data on recent trends in PTE incidence are limited. This study evaluated the recent incidence rate of PTE.
Methods: We performed a retrospective chart review of patients with PTE admitted to Chung-Ang University Hospit..
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Cardiology / Original Article
LPL gene Pvu II polymorphism and hypertriglyceridemia: a meta-analysis involving 1,640 subjects
Yan-yan Li, Yan-hong Zhou, Ge Gong, Hong-yu Geng, Xin-xing Yang, Xiang-ming Wang, Chuan-wei Zhou, Jian Xu, Yun Qian
Korean J Intern Med. 2017;32(6):1018-1024. Published online May 16, 2017
Background/Aims: Although lipoprotein lipase (LPL) gene Pvu II polymorphism has been associated with an increased risk of hypertriglyceridemia (HT), there is no clear consensus within the scientific community.
Methods: A meta-analysis of 1,640 subjects from six individual studies was conduct..
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Rheumatology / Review
New insights into the genetics of fibromyalgia
Dong-Jin Park, Shin-Seok Lee
Korean J Intern Med. 2017;32(6):984-995. Published online October 23, 2017
Although debate on the concept of fibromyalgia (FM) has been vigorous ever since the classification criteria were first published, FM is now better understood and has become recognized as a disorder. Recently, FM has come to be considered a major health problem, affecting 1% to 5% of the general pop..
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Endocrinology-metabolism / Original Article
Low serum bilirubin level predicts the development of chronic kidney disease in patients with type 2 diabetes mellitus
Kang Hee Ahn, Sang Soo Kim, Won Jin Kim, Jong Ho Kim, Yun Jeong Nam, Su Bin Park, Yun Kyung Jeon, Bo Hyun Kim, In Joo Kim, Yong Ki Kim
Korean J Intern Med. 2017;32(5):875-882. Published online May 31, 2017
Background/Aims: We evaluated whether serum bilirubin levels can predict the development of chronic kidney disease (CKD) in patients with type 2 diabetes mellitus (T2DM).
Methods: This was a retrospective observational longitudinal study of patients presenting at the Pusan National University Hospi..
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Pulmonology / Original Article
The activation of NLRP3-inflammsome by stimulation of diesel exhaust particles in lung tissues from emphysema model and RAW 264.7 cell line
Soo-Taek Uh, So My Koo, Yangki Kim, Kiup Kim, Sungwoo Park, An Soo Jang, Dojin Kim, Yong Hoon Kim, Choon-Sik Park
Korean J Intern Med. 2017;32(5):865-874. Published online August 18, 2017
Background/Aims: Diesel exhaust particles (DEPs) lead to elevation of reactive oxygen species, which can activate the nucleotide-binding oligomerization domain-like receptor (NLR) family members containing the pyrin domain 3 (NLRP3)-inf lammasome. In this study, we elucidated whether NLRP3 -inf lamm..
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