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Hemato-oncology / Original Article
Third-line docetaxel chemotherapy for recurrent and metastatic gastric cancer
Ji Hyun Lee, Sung-Hyun Kim, Sung Yong Oh, Suee Lee, Hojin Lee, Hye Jung Lee, Hyo-Jin Kim
Korean J Intern Med. 2013;28(3):314-321. Published online May 1, 2013
Background/AimsTo determine the efficacy and toxicity of docetaxel as a third-line therapy for patients with relapsed gastric cancer who have undergone modified oxaliplatin-fluorouracil (m-FOLFOX)-4 and modified irinotecan-fluorouracil (m-FOLFIRI) regimens.
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Endocrinology-metabolism / Original Article
Insulin secretion and insulin resistance in Korean women with gestational diabetes mellitus and impaired glucose tolerance
Sae Jeong Yang, Tae Nyun Kim, Sei Hyun Baik, Tae Sun Kim, Kwan Woo Lee, Moonsuk Nam, Yong Soo Park, Jeong-Teak Woo, Young Seol Kim, Sung-Hoon Kim
Korean J Intern Med. 2013;28(3):306-313. Published online May 1, 2013
Background/AimsThe aim was to compare the insulin sensitivity and secretion index of pregnant Korean women with normal glucose tolerance (NGT), gestational impaired glucose tolerance (GIGT; only one abnormal value according to the Carpenter and Coustan criteria), and gestation..
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Cardiology / Original Article
Serum bilirubin as a prognostic marker in patients with acute decompensated heart failure
Jayakrishna Chintanaboina, Matthew S. Haner, Arjinder Sethi, Nimesh Patel, Walid Tanyous, Alexander Lalos, Sameer Pancholy
Korean J Intern Med. 2013;28(3):300-305. Published online May 1, 2013
Background/AimsSeveral prognostic markers for heart failure (HF) have been determined but the importance of liver function tests (LFTs) remains unknown. The aim of this study was to determine the prognostic significance, if any, of abnormal LFTs in acute decompensated HF. <..
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Infectious diseases / Review
Procalcitonin as a biomarker of infectious diseases
Hyuck Lee
Korean J Intern Med. 2013;28(3):285-291. Published online May 1, 2013
Traditional biomarkers, including C-reactive protein, leukocytes, erythrocyte sedimentation rate, and clinical signs and symptoms, are not sufficiently sensitive or specific enough to guide treatment decisions in infectious febrile diseases. Procalcitonin (PCT) is synthesized by a large number of..
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Nephrology / Review
Current status and standards for establishment of hemodialysis units in Korea
Young-Ki Lee, Kiwon Kim, Dae Joong Kim
Korean J Intern Med. 2013;28(3):274-284. Published online May 1, 2013
The number of hemodialysis patients and dialysis facilities is increasing each year, but there are no surveillance programs validating that the services and equipment of each hemodialysis unit meet specified safety and quality standards. There is a concern that excessive competition and illegal a..
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Hemato-oncology / Review
Diagnosis and therapy of multiple myeloma
Antonio Palumbo, Chiara Cerrato
Korean J Intern Med. 2013;28(3):263-273. Published online May 1, 2013
Many advances in the treatment of multiple myeloma have been made due to the use of transplantation and the introduction of novel agents including thalidomide, lenalidomide, and bortezomib. The first step is recognizing the symptoms and starting prompt treatment. Different strategies should be se..
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Letter to the editor
A third case of USA300 community-associated methicillin-resistant Staphylococcus aureus infection in Korea
Seungjin Lim, Doo Ryeon Chung, Jin Yang Baek, So Hyun Kim, Kyong Ran Peck, Nam-Yong Lee, Jae-Hoon Song
Korean J Intern Med. 2013;28(2):258-260. Published online February 27, 2013
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Letter to the editor
A case of membranoproliferative glomerulonephritis associated with metastatic colon cancer
Jung-Hwa Ryu, Soon Sup Chung, Dong-Ryeol Ryu, Seung-Jung Kim, Duk-Hee Kang, Sun Hee Sung, Kyu-Bok Choi
Korean J Intern Med. 2013;28(2):254-257. Published online February 27, 2013
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Letter to the editor
Ischemic monomelic neuropathy: a rare complication after vascular access formation
Ji Soo Han, Moo Yong Park, Soo Jeong Choi, Jin Kuk Kim, Seung Duk Hwang, Keun Her, Tae Eun Kim
Korean J Intern Med. 2013;28(2):251-253. Published online February 27, 2013
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Letter to the editor
Intracardiac foreign body caused by cement leakage as a late complication of percutaneous vertebroplasty
Hyun-Tae Kim, Yoon-Nyun Kim, Hong-Won Shin, In-Cheol Kim, Hyungseop Kim, Nam-Hee Park, Sae-Young Choi
Korean J Intern Med. 2013;28(2):247-250. Published online February 27, 2013
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Case Report
Subacute thyroiditis presenting as acute psychosis: a case report and literature review
Kyung Ae Lee, Kyung Taek Park, Hea Min Yu, Heung Yong Jin, Hong Sun Baek, Tae Sun Park
Korean J Intern Med. 2013;28(2):242-246. Published online February 27, 2013
We describe herein an unusual case of subacute thyroiditis presenting as acute psychosis. An 18-year-old male presented at the emergency department due to abnormal behavior, psychomotor agitation, sexual hyperactivity, and a paranoid mental state. Laboratory findings included an erythrocyte sedim..
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Case Report
Case of concurrent Riedel's thyroiditis, acute suppurative thyroiditis, and micropapillary carcinoma
Ji Taek Hong, Jung Hwan Lee, So Hun Kim, Seong Bin Hong, Moonsuk Nam, Yong Seong Kim, Young Chae Chu
Korean J Intern Med. 2013;28(2):236-241. Published online February 27, 2013
Riedel's thyroiditis (RT) is a rare chronic inflammatory disease of the thyroid gland. It is characterized by a fibroinflammatory process that partially destroys the gland and extends into adjacent neck structures. Its clinical manifestation can mask an accompanying thyroid neoplasm and can mimic..
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Case Report
A case of secondary syphilis presenting as multiple pulmonary nodules
Se Joong Kim, Ju-Han Lee, Eung-Seok Lee, Il-Hwan Kim, Hyung Joo Park, Chol Shin, Je Hyeong Kim
Korean J Intern Med. 2013;28(2):231-235. Published online February 27, 2013
Syphilis is a sexually transmitted disease caused by Treponema pallidum. The prevalence of this disease has recently increased worldwide. However, pulmonary involvement in secondary syphilis is extremely rare. A 51-year-old heterosexual male patient presented with multiple pulmon..
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Case Report
Electrocardiographic artefacts mimicking atrial tachycardia resulted in unnecessary diagnostic and therapeutic measures
Shams Y-Hassan, Christer Sylvén
Korean J Intern Med. 2013;28(2):224-230. Published online February 27, 2013
Electrocardiographic (ECG) artefacts may closely simulate both supraventricular and ventricular tachycardias. We describe a case initially diagnosed as rapid atrial fibrillation, based on 12-lead surface ECG (especially the limb leads) and monitor tracing. The arrhythmia was resistant to beta blo..
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Allergy / Original Article
The effects of pycnogenol on antioxidant enzymes in a mouse model of ozone exposure
Min-Sung Lee, Kuk-Young Moon, Da-Jeong Bae, Moo-Kyun Park, An-Soo Jang
Korean J Intern Med. 2013;28(2):216-223. Published online February 27, 2013
Background/AimsOzone is an environmentally reactive oxidant, and pycnogenol is a mixture of flavonoid compounds extracted from pine tree bark that have antioxidant activity. We investigated the effects of pycnogenol on reactive nitrogen species, antioxidant responses, and airw..
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Rheumatology / Original Article
Is the frequency of metabolic syndrome higher in South Korean women with rheumatoid arthritis than in healthy subjects?
Seung-Geun Lee, Ji-Min Kim, Sun-Hee Lee, Kye-Hyung Kim, Ji-Hye Kim, Ji-Won Yi, Woo-Jin Jung, Young-Eun Park, Seong-Hu Park, Joung-Wook Lee, Seung-Hoon Baek, Jun-Hee Lee, Geun-Tae Kim
Korean J Intern Med. 2013;28(2):206-215. Published online February 27, 2013
Background/AimsTo compare the frequency of metabolic syndrome (MetS) and magnitude of insulin resistance, measured by the homeostatic model assessment of insulin resistance (HOMA-IR), between South Korean women with rheumatoid arthritis (RA) and healthy subjects, and to evalua..
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Nephrology / Original Article
Additional antihypertensive effect of magnesium supplementation with an angiotensin II receptor blocker in hypomagnesemic rats
Kyubok Jin, Tae Hee Kim, Yeong Hoon Kim, Yang Wook Kim
Korean J Intern Med. 2013;28(2):197-205. Published online February 27, 2013
Background/AimsMagnesium (Mg) is an essential element for vascular function and blood pressure regulation. Several studies have demonstrated that Mg concentration is inversely associated with blood pressure, and that Mg supplementation attenuates hypertension. The purpose of t..
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Gastroenterology / Original Article
Clinical characteristics and the usefulness of the QuantiFERON-TB Gold In-Tube test in hematologic patients with hepatic or splenic lesions
Jae-Cheol Kwon, Si-Hyun Kim, Sun Hee Park, Su-Mi Choi, Dong-Gun Lee, Jung-Hyun Choi, Jin-Hong Yoo, Yoo-Jin Kim, Seok Lee, Hee-Je Kim, Seok-Goo Cho, Jong-Wook Lee, Woo-Sung Min
Korean J Intern Med. 2013;28(2):187-196. Published online February 27, 2013
Background/AimsHepatic or splenic lesions in hematologic patients are not defined well because they are not easy to evaluate due to limitations of invasive procedures. Management typically depends on the clinical diagnosis with few microbiological data. Me..
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Endocrinology-metabolism / Original Article
Elevated thyroid stimulating hormone levels are associated with metabolic syndrome in euthyroid young women
Jee-Young Oh, Yeon-Ah Sung, Hye Jin Lee
Korean J Intern Med. 2013;28(2):180-186. Published online February 27, 2013
Background/AimsThe existence of an association between thyrotropin (thyroid stimulating hormone, TSH) levels and metabolic derangement in euthyroid subjects is controversial. We examined the association between high normal TSH levels and metabolic syndrome in healthy young wom..
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Pulmonology / Original Article
Clinical characteristics and treatment responses of patients who developed tuberculosis following use of a tumor necrosis factor-α inhibitor
Keun Bum Chung, Eun Young Lee, Jong Pil Im, Sung Koo Han, Jae-Joon Yim
Korean J Intern Med. 2013;28(2):174-179. Published online February 27, 2013
Background/AimsIndividuals being treated with tumor necrosis factor (TNF)-α inhibitors are at increased risk of developing tuberculosis (TB). We determined the clinical characteristics and treatment response of patients who developed TB after using TNF-α inhibitors. ..
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