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Cardiology / Original Article
Interleukin-33, matrix metalloproteinase-9, and tissue ınhibitor of matrix metalloproteinase-1 in myocardial infarction
Savas Guzel, Ozden Serin, Eda Celik Guzel, Banu Buyuk, Güzin Yılmaz, Guvenc Güvenen
Korean J Intern Med. 2013;28(2):165-173. Published online February 27, 2013
Background/AimsAcute coronary syndrome (ACS) is characterized by increased inflammatory processes and endothelial activation. We investigated the association between ACS and inflammatory mediators and matrix-degrading enzymes. MethodsWe prospect..
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Hemato-oncology / Review
Molecular targeted therapy for advanced gastric cancer
Jong Gwang Kim
Korean J Intern Med. 2013;28(2):149-155. Published online February 27, 2013
Although medical treatment has been shown to improve quality of life and prolong survival, no significant progress has been made in the treatment of advanced gastric cancer (AGC) within the last two decades. Thus, the optimum standard first-line chemotherapy regimen for AGC remains debatable, and..
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Gastroenterology / Review
Can postendoscopic retrograde cholangiopancreatography pancreatitis be prevented by a pharmacological approach?
Young Koog Cheon
Korean J Intern Med. 2013;28(2):141-148. Published online February 27, 2013
Acute pancreatitis remains the most frequent complication of endoscopic retrograde cholangiopancreatography (ERCP), with reported incidence rates that have changed little over several decades. Patient- and procedure-related risk factors for post-ERCP pancreatitis (PEP) are well-defined. Effective..
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Pulmonology / Review
Carbon monoxide: present and future indications for a medical gas
Stefan W. Ryter, Augustine M. K. Choi
Korean J Intern Med. 2013;28(2):123-140. Published online February 27, 2013
Gaseous molecules continue to hold new promise in molecular medicine as experimental and clinical therapeutics. The low molecular weight gas carbon monoxide (CO), and similar gaseous molecules (e.g., H2S, nitric oxide) have been implicated as potential inhalation therapies in inflammat..
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Letter to the editor
Migration of a sirolimus-eluting stent from the ostium of the left main coronary artery to the right deep femoral artery
Ki-Bum Won, Byeong-Keuk Kim, Young-Guk Ko, Myeong-Ki Hong, Yangsoo Jang, Won-Heum Shim
Korean J Intern Med. 2013;28(1):116-119. Published online December 28, 2012
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Letter to the editor
Pulmonary thromboembolism due to severe hyperhomocysteinemia associated with a methyltetrahydrofolate reductase mutation
Kyung Hoon Cho, Myung Ho Jeong, Doo Sun Sim, Young Joon Hong, Ju Han Kim, Youngkeun Ahn, Jung Chaee Kang
Korean J Intern Med. 2013;28(1):112-115. Published online December 28, 2012
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Letter to the editor
Zotarolimus-eluting stent-induced hypersensitivity pneumonitis
Hong-Won Shin, Chang-Wook Nam, Hyungseop Kim, Seung-Ho Hur, Yoon-Nyun Kim, Kwon-Bae Kim, Kun-Young Kwon
Korean J Intern Med. 2013;28(1):108-111. Published online December 28, 2012
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Letter to the editor
Ramosetron might be useful for treating diabetic diarrhea with a rapid small bowel transit time
Tae Hee Lee, Joon Seong Lee
Korean J Intern Med. 2013;28(1):106-107. Published online December 28, 2012
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Case Report
Tuberculosis of the urachal cyst
Tarun Jindal, Mir Reza Kamal, Jayesh Kumar Jha
Korean J Intern Med. 2013;28(1):103-105. Published online December 28, 2012
Urachal cysts are uncommon. Rarely, these cysts can become infected. Tuberculosis of the urachal cyst is exceedingly rare, with only one case reported previously in the English language literature. Here we report the case of a 23-year-old male who presented with an infra-umbilical mass that turne..
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Case Report
Type B insulin-resistance syndrome presenting as autoimmune hypoglycemia, associated with systemic lupus erythematosus and interstitial lung disease
Seon Mee Kang, Heung Yong Jin, Kyung Ae Lee, Ji Hyun Park, Hong Sun Baek, Tae Sun Park
Korean J Intern Med. 2013;28(1):98-102. Published online December 28, 2012
We describe an unusual case of systemic lupus erythematosus with pulmonary manifestations presenting as hypoglycemia due to anti-insulin receptor antibodies. A 38-year-old female suffered an episode of unconsciousness and was admitted to hospital where her blood glucose was found to be 18 mg/dL. ..
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Case Report
Mycobacterium avium lung disease combined with a bronchogenic cyst in an immunocompetent young adult
Yong Soo Kwon, Joungho Han, Ki Hwan Jung, Je Hyeong Kim, Won-Jung Koh
Korean J Intern Med. 2013;28(1):94-97. Published online December 28, 2012
We report a very rare case of a bronchogenic cyst combined with nontuberculous mycobacterial pulmonary disease in an immunocompetent patient. A 21-year-old male was referred to our institution because of a cough, fever, and worsening of abnormalities on his chest radiograph, despite anti-tubercul..
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Case Report
A case of papillary fibroelastoma in the left ventricle
Joo Yong Hyun, In Hyun Jung, Hyun Jong Lee, Sook Jin Lee, Jin Seok Kim, Chan Young Na, Young Moo Ro
Korean J Intern Med. 2013;28(1):89-93. Published online December 28, 2012
Cardiac papillary fibroelastoma (CPF) is a rare and benign primary cardiac neoplasm of unknown prevalence. The incidence of CPF in the left ventricle is lower than that in other parts of the heart. A 65-year-old female was referred to our cardiology department for evaluation of a cardiac mass of..
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Endocrinology-metabolism / Original Article
Analysis of 18F-fluorodeoxyglucose positron emission tomography findings in patients with pituitary lesions
Hannah Seok, Eun Young Lee, Eun Yeong Choe, Woo In Yang, Joo Young Kim, Dong Yeob Shin, Ho Jin Cho, Tae Sung Kim, Mi Jin Yun, Jong Doo Lee, Eun Jig Lee, Sung-Kil Lim, Yumie Rhee
Korean J Intern Med. 2013;28(1):81-88. Published online December 28, 2012
Background/AimsAlthough magnetic resonance imaging (MRI) is a good visual modality for the evaluation of pituitary lesions, it has limited value in the diagnosis of mixed nodules and some cystic lesions. We evaluated the usefulness of 18F-fluorodeoxyglucose positron..
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Cardiology / Original Article
Clinical outcomes between different stent designs with the same polymer and drug: comparison between the Taxus Express and Taxus Liberte stents
Jang-Won Son, Ung Kim, Jong-Seon Park, Young-Jo Kim, Jae-Sik Jang, Tae-Hyun Yang, Dong-Soo Kim, Dong-Kie Kim, Sang-Hoon Seol, Doo-Il Kim, Chang-Wook Nam, Seung-Ho Hur, Kwon-Bae Kim
Korean J Intern Med. 2013;28(1):72-80. Published online December 28, 2012
Background/AimsThe Taxus Liberte stent (Boston Scientific Co.) evolved from the Taxus Express stent, with enhanced stent deliverability and uniform drug delivery. This study was designed to compare angiographic and clinical outcomes in real-world practice between the Taxus Lib..
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Gastroenterology / Original Article
Neck circumference correlates with tumor size and lateral lymph node metastasis in men with small papillary thyroid carcinoma
Mi Ra Kim, Sang Soo Kim, Jung Eun Huh, Byung Joo Lee, Jin Choon Lee, Yun Kyung Jeon, Bo Hyun Kim, Seong Jang Kim, Soo Geun Wang, Yong Ki Kim, In Joo Kim
Korean J Intern Med. 2013;28(1):62-71. Published online December 28, 2012
Background/AimsObesity is correlated with numerous diseases, including thyroid cancer, but the clinical significance of obesity with regard to the clinical characteristics of thyroid cancer remains unclear. Neck circumference is an index of upper-body adipose tissue distributi..
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Gastroenterology / Original Article
Rectal hyposensitivity and functional anorectal outlet obstruction are common entities in patients with functional constipation but are not significantly associated
Tae Hee Lee, Joon Seong Lee, Su Jin Hong, Seong Ran Jeon, Soon Ha Kwon, Wan Jung Kim, Hyun Gun Kim, Won Young Cho, Joo Young Cho, Jin-Oh Kim, Ji Sung Lee
Korean J Intern Med. 2013;28(1):54-61. Published online December 28, 2012
Background/AimsThe causes of functional anorectal outlet obstruction (outlet obstruction) include functional defecation disorder (FDD), rectocele, and rectal intussusception (RI). It is unclear whether outlet obstruction is associated with rectal hyposensitivity (RH) in patien..
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Rheumatology / Original Article
Greater prevalence of seropositivity for anti-cyclic citrullinated peptide antibody in unaffected first-degree relatives in multicase rheumatoid arthritis-affected families
Seong-Kyu Kim, Jisuk Bae, Hwajeong Lee, Ji Hun Kim, Sung-Hoon Park, Jung-Yoon Choe
Korean J Intern Med. 2013;28(1):45-53. Published online December 28, 2012
Background/AimsThis study determined the prevalence and determinants of seropositivity for rheumatoid factor (RF), anti-cyclic citrullinated peptide (anti-CCP) antibody, and anti-mutated citrullinated vimentin (anti-MCV) antibody in unaffected first-degree relatives (FDRs) of ..
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Nephrology / Original Article
Tissue Doppler-derived E/e' ratio as a parameter for assessing diastolic heart failure and as a predictor of mortality in patients with chronic kidney disease
Min Keun Kim, Biro Kim, Jun Young Lee, Jae Seok Kim, Byoung-Geun Han, Seung Ok Choi, Jae Won Yang
Korean J Intern Med. 2013;28(1):35-44. Published online December 28, 2012
Background/AimsDiastolic dysfunction occurs frequently in patients with chronic kidney disease (CKD) and is associated with heart failure (HF) or mortality. We investigated whether the ratio of early diastolic mitral inflow velocity to early diastolic mitral annulus velocity (..
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Endocrinology-metabolism / Original Article
Gender disparity in the secular trends for obesity prevalence in Korea: analyses based on the KNHANES 1998-2009
Sang Youl Rhee, Seok Won Park, Dae Jung Kim, Jeongtaek Woo
Korean J Intern Med. 2013;28(1):29-34. Published online December 28, 2012
Background/AimsA similar gender-associated trend in obesity is observed worldwide. Nevertheless, systematic analyses of gender-specific characteristics in the general Korean population are rare. MethodsWe analyzed the prevalence of obesity in Ko..
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Gastroenterology / Review
Endoscopic drainage in patients with inoperable hilar cholangiocarcinoma
Ye Jin Park, Dae Hwan Kang
Korean J Intern Med. 2013;28(1):8-18. Published online December 28, 2012
Hilar cholangiocarcinoma has an extremely poor prognosis and is usually diagnosed at an advanced stage. Palliative management plays an important role in the treatment of patients with inoperable hilar cholangiocarcinoma. Surgical, percutaneous, and endoscopic biliary drainage are three modalities..
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