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Original Article
The Body Mass Index as a Prognostic Factor of Critical Care
So Yeon Lim, So I Kim, Yon Ju Ryu, Jin Hwa Lee, Eun Mi Chun, Jung Hyun Chang
Korean J Intern Med. 2010;25(2):162-167. Published online June 1, 2010
Background/AimsObesity is a worldwide concern, but its influence on critical care outcomes is not well understood. We tested the hypothesis that abnormal body mass index (BMI) would be an independent predictor of higher mortality rates in intensive care unit (ICU).
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Original Article
The Impact of Generic Clopidogrel Bisulfate on Platelet Inhibition in Patients with Coronary Artery Stents: Results of the ACCEL-GENERIC Study
Young-Hoon Jeong, Jin-Sin Koh, Min-Kyung Kang, Yeon-Jeong Ahn, In-Suk Kim, Yongwhi Park, Seok-Jae Hwang, Choong Hwan Kwak, Jin-Yong Hwang
Korean J Intern Med. 2010;25(2):154-161. Published online June 1, 2010
Background/AimsIn patients with coronary artery stents, the cost of clopidogrel has been cited as a factor in the premature discontinuation of therapy. Thus, the introduction of lower-cost generic clopidogrel may increase patient compliance. However, platelet inhibition by ge..
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Original Article
Characteristics of Double-Chambered Right Ventricle in Adult Patients
Yu Jeong Choi, Seung Woo Park
Korean J Intern Med. 2010;25(2):147-153. Published online June 1, 2010
Background/AimsThis study evaluated the clinical features of double-chambered right ventricle (DCRV) in adults. Most cases of DCRV are diagnosed and treated during childhood. Consequently, very few reports include cases in which its clinical characteristics are evident in adul..
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Original Article
Clinical Characteristics of Colonic Diverticulosis in Korea: A Prospective Study
Jung Hoon Song, You Sun Kim, Jin Ho Lee, Kyung Sun Ok, Soo Hyung Ryu, Jung Hwan Lee, Jeong Seop Moon
Korean J Intern Med. 2010;25(2):140-146. Published online June 1, 2010
Background/AimsThe prevalence of colonic diverticulosis has been reported to be lower in Korea than in Western countries. This disease also shows markedly different characteristics in the Korean population. We describe herein a prospective investigation, based on colonoscopic ..
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Original Article
Diet and Airway Obstruction: A Cross Sectional Study from the Second Korean National Health and Nutrition Examination Survey
Jin Hwa Lee, Yun Su Sim, Gee Young Suh, Jeong-Seon Ryu, Dong Ho Shin, Kyung Haeng Koh, Yeon Jae Kim, Wan Park, Hyoung Kyu Yoon, Man Jae Lee, Jung Hyun Chang,
Korean J Intern Med. 2010;25(2):132-139. Published online June 1, 2010
Background/AimsSeveral dietary factors, such as antioxidant vitamins, have potential roles in the development of obstructive lung diseases. However, the results of studies on the relationships between dietary factors and obstructive lung diseases are inconsistent. The aim of t..
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Review
Molecular Mechanism of Insulin Resistance in Obesity and Type 2 Diabetes
Kangduk Choi, Young-Bum Kim
Korean J Intern Med. 2010;25(2):119-129. Published online June 1, 2010
Insulin resistance is a major risk factor for developing type 2 diabetes caused by the inability of insulin-target tissues to respond properly to insulin, and contributes to the morbidity of obesity. Insulin action involves a series of signaling cascades initiated by insulin binding to its recept..
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Case Report
Klebsiella pneumoniae Orbital Cellulitis with Extensive Vascular Occlusions in a Patient with Type 2 Diabetes
Sae Jeong Yang, Soo Yeon Park, Yun Jeong Lee, Hee Young Kim, Ji A Seo, Sin Gon Kim, Dong Seop Choi
Korean J Intern Med. 2010;25(1):114-117. Published online February 26, 2010
A 39-year-old woman visited the emergency room complaining of right eye pain and swelling over the preceding three days. The ophthalmologist's examination revealed orbital cellulitis and diabetic retinopathy in the right eye, although the patient had no prior diagnosis of diabetes. It was therefo..
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Case Report
A Case Report of the Second de Novo Acute Myeloid Leukemia (AML) Following Allogeneic Stem Cell Transplantation in a Patient with the First AML
Byung-Sik Cho, Hee-Je Kim, Ki-Sung Eom, Jong-Wook Lee, Woo-Sung Min, Chun-Choo Kim
Korean J Intern Med. 2010;25(1):110-113. Published online February 26, 2010
Secondary leukemia occurring after hematopoietic stem cell transplantation (HSCT) for acute myeloid leukemia (AML) is rare. Secondary AML usually follows autologous and not allogeneic transplants. When a new leukemia develops in a patient successfully treated with an allogeneic HSCT, the possibil..
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Case Report
A Case of Rhabdomyolysis Associated with Use of a Pneumatic Tourniquet during Arthroscopic Knee Surgery
Yong Gu Lee, Woong Park, Sang Hoon Kim, Sang Pil Yun, Hun Jeong, Hyung Jong Kim, Dong Ho Yang
Korean J Intern Med. 2010;25(1):105-109. Published online February 26, 2010
The common causes of rhabdomyolysis include trauma, hypoxia, drugs, toxins, infections and hyperthermia. Operative insults, including direct trauma and ischemia, have the potential to cause the development of rhabdomyolysis. Pneumatic tourniquets used during arthroscopic knee surgery to prevent b..
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Case Report
Myasthenia Gravis Presenting as Isolated Respiratory Failure: A Case Report
Won Hee Kim, Jung Hyun Kim, Eun Kyung Kim, Sang Pil Yun, Kyung Keun Kim, Won Chan Kim, Hye Cheol Jeong
Korean J Intern Med. 2010;25(1):101-104. Published online February 26, 2010
Myasthenia gravis (MG) is often complicated by respiratory failure, known as a myasthenic crisis. However, most of the patients who develop respiratory symptoms do so during the late course of disease and have other neurological signs and symptoms. However, in some patients respiratory failure is..
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Original Article
Ethyl Acetate Fraction from Cudrania Tricuspidata Inhibits IL-1β-Stimulated Osteoclast Differentiation through Downregulation of MAPKs, c-Fos and NFATc1
Eun-Gyeong Lee, Hee-Jin Yun, Sang-Il Lee, Wan-Hee Yoo
Korean J Intern Med. 2010;25(1):93-100. Published online February 26, 2010
Background/AimsThe present study was performed to determine the effects of the ethyl acetate extract of Cudrania tricuspidata (EACT) on interleukin (IL)-1β-stimulated receptor activator of NF-κB ligand (RANKL)-mediated osteoclast differentiation.
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Original Article
Severe Pulmonary Adverse Effects in Lymphoma Patients Treated with Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (CHOP) Regimen Plus Rituximab
Kyu-Hyoung Lim, Ho-Il Yoon, Young Ae Kang, Keun-Wook Lee, Jee Hyun Kim, Soo-Mee Bang, Jae Ho Lee, Choon-Taek Lee, Jong Seok Lee
Korean J Intern Med. 2010;25(1):86-92. Published online February 26, 2010
Background/AimsThe aim of our study was to determine the incidence and clinical features of severe pulmonary complications in patients receiving cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) or rituximab plus CHOP (R-CHOP) as the initial treatment for lymph..
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Original Article
Detecting Bacterial Growth in Continuous Ambulatory Peritoneal Dialysis Effluent Using Two Culture Methods
Se-Hee Yoon, Nak Won Choi, Sung-Ro Yun
Korean J Intern Med. 2010;25(1):82-85. Published online February 26, 2010
Background/AimsThe aim of this study was to evaluate the peritonitis-causing bacteria detected in peritoneal fluid using a blood culture bottle in patients undergoing continuous ambulatory peritoneal dialysis (CAPD). MethodsOne-hundred and eleve..
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Original Article
Application of Cystatin C Reduction Ratio to High-Flux Hemodialysis as an Alternative Indicator of the Clearance of Middle Molecules
Joon-Sung Park, Gheun-Ho Kim, Chong Myung Kang, Chang Hwa Lee
Korean J Intern Med. 2010;25(1):77-81. Published online February 26, 2010
Background/AimsAlthough high-flux (HF) dialyzers with enhanced membrane permeability are widely used in current hemodialysis (HD) practice, urea kinetic modeling is still being applied to indicate the adequacy of both low-flux (LF) and HF HD. In comparison with urea (molecular..
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Original Article
Ultrasonographic Features of Papillary Thyroid Carcinoma in Patients with Graves' Disease
Jin Ook Chung, Dong Hyeok Cho, Dong Jin Chung, Min Young Chung
Korean J Intern Med. 2010;25(1):71-76. Published online February 26, 2010
Background/AimsTo characterize ultrasonographic findings in papillary thyroid carcinoma (PTC) combined with Graves' disease. MethodsMedical records and ultrasonographic findings of 1,013 patients with Graves' disease and 3,380 patients without G..
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Original Article
Clinical Characteristics of Pulmonary Embolism with Underlying Malignancy
Ji Eun Lee, Hye-Ryoun Kim, Sang-Min Lee, Jae-Joon Yim, Chul-Gyu Yoo, Young Whan Kim, Sung Koo Han, Young-Soo Shim, Seok-Chul Yang
Korean J Intern Med. 2010;25(1):66-70. Published online February 26, 2010
Background/AimsThe risk of venous thromboembolism (VTE), which encompasses deep vein thrombosis and pulmonary embolism (PE), increases in patients with cancer. Anticancer treatment is also associated with an increased risk for VTE. We conducted this study to investigate the cl..
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Original Article
Clinical Meaning of Early Oxygenation Improvement in Severe Acute Respiratory Distress Syndrome under Prolonged Prone Positioning
Kwangha Lee, Mi-Young Kim, Jung-Wan Yoo, Sang-Bum Hong, Chae-Man Lim, Younsuck Koh
Korean J Intern Med. 2010;25(1):58-65. Published online February 26, 2010
Background/AimsVentilating patients with acute respiratory distress syndrome (ARDS) in the prone position has been shown to improve arterial oxygenation, but prolonged prone positioning frequently requires continuous deep sedation, which may be harmful to patients. We evaluated..
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Original Article
Prevalence of Depression and Anxiety in Outpatients with Chronic Airway Lung Disease
Yon Ju Ryu, Eun-Mi Chun, Jin Hwa Lee, Jung Hyun Chang
Korean J Intern Med. 2010;25(1):51-57. Published online February 26, 2010
Background/AimsPatients with chronic airway lung diseases often experience depression and anxiety, but little information is available regarding Koreans with these conditions. We thus assessed depression and anxiety in Korean patients with chronic airway lung diseases.
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Original Article
Relation of Anti- to Pro-Inflammatory Cytokine Ratios with Acute Myocardial Infarction
Santanu Biswas, Pradip K. Ghoshal, Sankar C. Mandal, Nripendranath Mandal
Korean J Intern Med. 2010;25(1):44-50. Published online February 26, 2010
Background/AimsAcute myocardial infarction (AMI) is a leading cause of death. Inflammatory processes play an important role in atherosclerosis, which is intimately related to AMI. The aim of this study was to investigate the association between anti-inflammatory and pro-inflam..
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Original Article
Acceptance and Understanding of the Informed Consent Procedure Prior to Gastrointestinal Endoscopy by Patients: A Single-Center Experience in Korea
Ji Hyun Song, Hwan Sik Yoon, Byung Hoon Min, Jun Haeng Lee, Young Ho Kim, Dong Kyung Chang, Hee Jung Son, Poong Lyul Rhee, Jong Chul Rhee, Jae J. Kim
Korean J Intern Med. 2010;25(1):36-43. Published online February 26, 2010
Background/AimsOnly a few reports have examined informed consent for gastrointestinal endoscopy in Korea. The aim of this study was to evaluate the appropriateness of the informed consent procedure in Korea. MethodsA total of 209 patients who un..
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