|
Cardiology / Review
Update on heart failure management and future directions
[corrected-article]
Hong-Mi Choi, Myung-Soo Park, Jong-Chan Youn
Korean J Intern Med. 2019;34(1):11-43. Published online December 28, 2018
Heart failure (HF) is an important cardiovascular disease because of its increasing prevalence, significant morbidity, high mortality, and rapidly expanding health care cost. The number of HF patients is increasing worldwide, and Korea is no exception. There have been marked advances in definition, ..
|
|
|
Cardiology / Review
Current status of acute myocardial infarction in Korea
Yongcheol Kim, Youngkeun Ahn, Myeong Chan Cho, Chong Jin Kim, Young Jo Kim, Myung Ho Jeong
Korean J Intern Med. 2019;34(1):1-10. Published online December 28, 2018
Coronary artery disease, especially acute myocardial infarction (AMI), is a leading cause of death in the Asia-Pacific region. The Korea Acute Myocardial Infarction Registry (KAMIR) is the first nationwide, prospective, multicenter registry of Korean patients with AMI. Since the KAMIR first began in..
|
|
|
Rheumatology / Original Article
Red blood cell distribution width is useful in discriminating adult onset Still’s disease and sepsis within 24 hours after hospitalization
Hee-Jin Park, Jungsik Song, Yong-Beom Park, Soo-Kon Lee, Sang-Won Lee
Korean J Intern Med. 2018;33(6):1234-1240. Published online August 25, 2017
Background/Aims: Red blood cell distribution width (RDW) is a value representing the heterogeneity in the size of red blood cell, and it is usually used in distinguishing types of anaemia. Recently, it was reported that it could reflect the burden of inflammation in diverse diseases and their progno..
|
|
|
Hemato-oncology / Original Article
No benefit of hypomethylating agents compared to supportive care for higher risk myelodysplastic syndrome
Sang Kyun Sohn, Joon Ho Moon, In Hee Lee, Jae Sook Ahn, Hyeoung Joon Kim, Joo Seop Chung, Ho Jin Shin, Sung Woo Park, Won Sik Lee, Sang Min Lee, Hawk Kim, Ho Sup Lee, Yang Soo Kim, Yoon Young Cho, Sung Hwa Bae, Ji Hyun Lee, Sung Hyun Kim, Ik Chan Song, Ji Hyun Kwon, Yoo Jin Lee
Korean J Intern Med. 2018;33(6):1194-1202. Published online December 15, 2017
Background/Aims: This study evaluated the role of hypomethylating agents (HMA) compared to best supportive care (BSC) for patients with high or very-high (H/VH) risk myelodysplastic syndrome (MDS) according to the Revised International Prognostic Scoring System.
Methods: A total of 279 H/VH risk MD..
|
|
|
Hemato-oncology / Original Article
The effect of the dexamethasone, cytarabine, and cisplatin (DHAP) regimen on stem cell mobilization and transplant outcomes of patients with non-Hodgkin’s lymphoma who are candidates for up-front autologous stem cell transplantation
So Yeon Jeon, Ho-Young Yhim, Hee Sun Kim, Jeong-A Kim, Deok-Hwan Yang, Jae-Yong Kwak
Korean J Intern Med. 2018;33(6):1169-1181. Published online January 8, 2018
Background/Aims: Data on dexamethasone, cytarabine, and cisplatin (DHAP) as a mobilization regimen, compared to high-dose cyclophosphamide (HDC), for up-front autologous stem cell transplantation (ASCT) in non-Hodgkin’s lymphoma (NHL) is limited.
Methods: Consecutive patients with aggressive NHL ..
|
|
|
Nephrology / Original Article
Current treatment status and medical costs for hemodialysis vascular access based on analysis of the Korean Health Insurance Database
Hyung Seok Lee, Young-Su Ju, Young Rim Song, Jwa Kyung Kim, Sun Ryoung Choi, Narae Joo, Hyung Jik Kim, Pyoungju Park, Sung Gyun Kim
Korean J Intern Med. 2018;33(6):1160-1168. Published online October 30, 2018
Background/Aims: The Republic of Korea is a country where the hemodialysis population is growing rapidly. It is believed that the numbers of treatments related to vascular access-related complications are also increasing. This study investigated the current status of treatment and medical expenses f..
|
|
|
Pulmonology / Original Article
Effect of vitamin D deficiency in Korean patients with acute respiratory distress syndrome
[corrected-article]
Sojung Park, Min Gi Lee, Sang-Bum Hong, Chae-Man Lim, Younsuck Koh, Jin Won Huh
Korean J Intern Med. 2018;33(6):1129-1136. Published online June 20, 2018
Background/Aims: Vitamin D modulates innate and adaptive immune responses, and vitamin D deficiency is associated with increased mortality in hospitalized patients with pneumonia. We evaluated the prevalence of vitamin D deficiency in Korean patients with acute respiratory distress syndrome (ARDS) a..
|
|
|
Cardiology / Original Article
Prognostic significance of non-chest pain symptoms in patients with non-ST-segment elevation myocardial infarction
Inna Kim, Min Chul Kim, Keun Ho Park, Doo Sun Sim, Young Joon Hong, Ju Han Kim, Myung Ho Jeong, Jeong Gwan Cho, Jong Chun Park, Myeong Chan Cho, Jong Jin Kim, Young Jo Kim, Youngkeun Ahn; the Korea Acute Myocardial Infarction Registry Investigators
Korean J Intern Med. 2018;33(6):1111-1118. Published online November 10, 2017
Background/Aims: Chest pain is an essential symptom in the diagnosis of acute coronary syndrome (ACS). One-third of patients with ACS present atypically, which can influence their receiving timely lifesaving therapy.
Methods: A total of 617 NSTEMI patients from the Korea Acute MI Registry (KAMIR) ..
|
|
|
Gastroenterology / Original Article
Clinical significance of radiation-induced liver disease after stereotactic body radiation therapy for hepatocellular carcinoma
Baek Gyu Jun, Young Don Kim, Gab Jin Cheon, Eun Seog Kim, Eunjin Jwa, Sang Gyune Kim, Young Seok Kim, Boo Sung Kim, Soung Won Jeong, Jae Young Jang, Sae Hwan Lee, Hong Soo Kim
Korean J Intern Med. 2018;33(6):1093-1102. Published online August 28, 2017
Background/Aims: The aim of this study was to investigate parameters that predict radiation-induced liver disease (RILD) following stereotactic body radiotherapy (SBRT) in patients with hepatocellular carcinoma (HCC) and to identify the clinical significance of RILD.
Methods: We retrospectively rev..
|
|
|
Gastroenterology / Original Article
Should asymptomatic young men with iron deficiency anemia necessarily undergo endoscopy?
Nam Hee Kim, Jung Ho Park, Dong Il Park, Chong Il Sohn, Kyuyong Choi, Yoon Suk Jung
Korean J Intern Med. 2018;33(6):1084-1092. Published online January 5, 2018
Background/Aims: There has been no evidence for the necessity of endoscopy in asymptomatic young men with iron deficiency anemia (IDA). To determine whether endoscopy should be recommended in asymptomatic young men with IDA, we compared the prevalence of gastrointestinal (GI) lesions between young m..
|
|
|
Infectious diseases / Review
Vibrio vulnificus infection: a persistent threat to public health
Na Ra Yun, Dong-Min Kim
Korean J Intern Med. 2018;33(6):1070-1078. Published online June 15, 2018
Vibrio vulnificus is a gram-negative bacterium that can cause serious, potentially fatal infections. V. vulnificus causes three distinct syndromes: an overwhelming primary septicemia caused by consuming contaminated seafood, wound infections acquired when an open wound is exposed to contaminated war..
|
|
|
Endocrinology-metabolism / Original Article
Depth and combined infection is important predictor of lower extremity amputations in hospitalized diabetic foot ulcer patients
Eun-Gyo Jeong, Sung Shim Cho, Sang-Hoon Lee, Kang-Min Lee, Seo-Kyung Woo, Yoongoo Kang, Jae-Seung Yun, Seon-Ah Cha, Yoon-Jung Kim, Yu-Bae Ahn, Seung-Hyun Ko, Jung-Min Lee
Korean J Intern Med. 2018;33(5):952-960. Published online June 7, 2017
Background/Aims: As the prevalence of diabetes mellitus and its complications increase rapidly, diabetic foot ulcers (DFUs), which are a major diabetic complication, are expected to increase. For prevention and effective treatment, it is important to understand the clinical course of DFUs. The aim o..
|
|
|
Gastroenterology / Original Article
Disparity in Crohn’s disease activity between home and clinics is associated with unscheduled hospital visits due to disease flares
Eun Soo Kim, Yoo Jin Lee, Byung Ik Jang, Kyeong Ok Kim, Eun Young Kim, Hyun Seok Lee, Seong Woo Jeon, Sang Gyu Kwak; on behalf of Crohn’s and Colitis Association in Daegu-Gyeongbuk (CCAiD)
Korean J Intern Med. 2018;33(5):902-910. Published online January 17, 2018
Background/Aims: E-health technologies have been implemented for the management of Crohn’s disease (CD). We aimed to identify differences between patient activities at home and at routine clinic visits using a web-based self-reporting CD symptom diary (CDSD) and to determine the impact of this dis..
|
|
|
Gastroenterology / Original Article
Characteristics of Helicobacter pylori-seropositive subjects according to the stool antigen test findings: a prospective study
Hee-Won Moon, Sun-Young Lee, Mina Hur, Yeo-Min Yun
Korean J Intern Med. 2018;33(5):893-901. Published online October 24, 2017
Background/Aims: In countries with a higher risk of gastric atrophic gastritis, noninvasive tests are helpful for a more reliable diagnosis of Helicobacter pylori infection. The aim of this study was to evaluate the characteristics of seropositive subjects according to their stool H. pylori a..
|
|
|
Cardiology / Review
Percutaneous coronary intervention in patients with multi-vessel coronary artery disease: a focus on physiology
Yun-Kyeong Cho, Chang-Wook Nam
Korean J Intern Med. 2018;33(5):851-859. Published online March 21, 2018
Multi-vessel coronary artery disease (MVD) frequently features ambiguous or intermediate lesions that may be both serial and complex, suggesting that multiple regions require revascularization. Percutaneous coronary intervention (PCI) is associated with various challenges such as appropriate identif..
|
|
|
Gastroenterology / Review
Immunoglobulin G4-related sclerosing cholangitis
George Goodchild, Stephen P. Pereira, George Webster
Korean J Intern Med. 2018;33(5):841-850. Published online July 27, 2018
Immunoglobulin G4-related disease (IgG4-RD) is a systemic fibroinflammatory condition of which IgG4-related sclerosing cholangitis (IgG4-SC) is the biliary manifestation. In this review, we provide an overview of IgG4-RD, with a focus on the biliary manifestations. In particular, we describe the imp..
|
|
|
Nephrology / Original Article
Notch signaling in the collecting duct regulates renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction in mice
Arum Choi, Sun Ah Nam, Wan-Young Kim, Sang Hee Park, Hyang Kim, Chul Woo Yang, Jin Kim, Yong Kyun Kim
Korean J Intern Med. 2018;33(4):774-782. Published online May 26, 2017
Background/Aims: Mind bomb-1 (Mib1) encodes an E3 ubiquitin ligase, which is required for the initiation of Notch signaling. Recently, it was demonstrated that the renal collecting duct plays an important role in renal fibrosis. Here, we investigated the role of Notch signaling in renal fibro..
|
|
|
Endocrinology-metabolism / Original Article
Prevalence of thyroid nodules and their associated clinical parameters: a large-scale, multicenter-based health checkup study
Jae Hoon Moon, Min Kyung Hyun, Ja Youn Lee, Jung Im Shim, Tae Hyuk Kim, Hoon Sung Choi, Hwa Young Ahn, Kyung Won Kim, Do Joon Park, Young Joo Park, Ka Hee Yi
Korean J Intern Med. 2018;33(4):753-762. Published online July 7, 2017
Background/Aims: We evaluated the prevalence and characteristics of thyroid nodules detected by thyroid ultrasound (US) at health checkups and the associated clinical parameters.
Methods: A total of 72,319 subjects who underwent thyroid US at three health checkup centers in Korea from January 2004 ..
|
|
|
Pulmonology / Original Article
Clinical and molecular characteristics of pulmonary sarcomatoid carcinoma
Jae Kyeom Sim, Sang Mi Chung, Jong Hyun Choi, Jee Youn Oh, Seung Heon Lee, Je Hyeong Kim, Kyung Hoon Min, Gyu Young Hur, Jae Jeong Shim, Kyung Ho Kang, Bong Kyung Shin, Ju Han Lee, Sung Yong Lee
Korean J Intern Med. 2018;33(4):737-744. Published online February 20, 2018
Background/Aims: Pulmonary sarcomatoid carcinoma (PSC) is a poorly differentiated non-small cell lung cancer (NSCLC) that contains components of spindle or giant cells. Owing to its low prevalence, there are insufficient data regarding its clinical features, therapeutic strategies and prognosis.
Me..
|
|
|
Cardiology / Original Article
Use of hypnotics and the risk of or mortality from heart disease: a meta-analysis of observational studies
Young-Hyo Kim, Hong-Bae Kim, Do-Hyoung Kim, Ja-Young Kim, Hyun-Young Shin
Korean J Intern Med. 2018;33(4):727-736. Published online August 28, 2017
Background/Aims: Some observational epidemiologic studies have reported conflicting results on the relationship between hypnotics use and the risk of developing and/or dying from heart disease. We investigated these associations using a meta-analysis of available literatures.
Methods: We searched t..
|
|
|
