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Cardiology / Original Article
Comparative occurrence of ischemic stroke with the rhythm versus rate control strategy in a national prospective cohort of atrial fibrillation
Jae Guk Kim, Young Soo Lee, Ki-Woon Kang, Eue-Keun Choi, Myung-Jin Cha, Jung-Myung Lee, Jin-Bae Kim, Junbeom Park, Jin-Kyu Park, Tae-Hoon Kim, Jae-Sun Uhm, Jaemin Shim, Jun Kim, HyungWook Park, Changsoo Kim, Boyoung Joung
Korean J Intern Med. 2021;36(1):114-123. Published online October 14, 2019
Background/Aims: Comparative occurrence of ischemic stroke for rhythm versus rate control strategy in patients with non-valvular atrial fibrillation (NVAF) is still inconclusive. The purpose of this study was to investigate whether the rhythm control strategy is associated with a lower risk of isch..
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Gastroenterology / Original Article
Risk for metabolic syndrome in the population with visceral fat area measured by bioelectrical impedance analysis
Han Ho Jeon, Yong Kang Lee, Dong Hyun Kim, Haeyong Pak, Sang Yun Shin, Jeong Hun Seo
Korean J Intern Med. 2021;36(1):97-105. Published online April 29, 2020
Background/Aims: To investigate whether visceral fat area (VFA) measured by bioelectric impedance analysis (BIA) was associated with metabolic syndrome in subjects with and without obesity.
Methods: A total 23,202 participants who underwent medical check-ups were assessed. Participants were stratif..
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Gastroenterology / Original Article
Role of tenofovir disoproxil fumarate in prevention of perinatal transmission of hepatitis B virus from mother to child: a systematic review and meta-analysis
Young-Sun Lee, Ha Seok Lee, Ji Hoon Kim, Sung Won Chang, Myung Han Hyun, Haein Bak, Sehwa Kim, Min-jin Lee, Chan Uk Lee, Young Kul Jung, Yeon Seok Seo, Hyung Joon Yim, Jong Eun Yeon, Soon Ho Um, Kwan Soo Byun
Korean J Intern Med. 2021;36(1):76-85. Published online December 31, 2019
Background/Aims: To prevent the perinatal transmission of hepatitis B virus (HBV) from mother to child, administration of an antiviral agent during pregnancy has been attempted in women who are either hepatitis B e antigen positive or have a high viral load. In this systematic review and meta-analys..
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Review
The 2020 revision of the guidelines for the management of myeloproliferative neoplasms
Sung-Yong Kim, Sung Hwa Bae, Soo-Mee Bang, Ki-Seong Eom, Junshik Hong, Seongsoo Jang, Chul Won Jung, Hee-Jin Kim, Ho Young Kim, Min Kyoung Kim, Soo-Jeong Kim, Yeung-Chul Mun, Seung-Hyun Nam, Jinny Park, Jong-Ho Won, Chul Won Choi
Korean J Intern Med. 2021;36(1):45-62. Published online December 4, 2020
In 2016, the World Health Organization revised the diagnostic criteria for myeloproliferative neoplasms (MPNs) based on the discovery of disease-driving genetic aberrations and extensive analysis of the clinical characteristics of patients with MPNs. Recent studies have suggested that additional som..
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Review
Gallstone pancreatitis: general clinical approach and the role of endoscopic retrograde cholangiopancreatography
Shanker Kundumadam, Evan L. Fogel, Mark Andrew Gromski
Korean J Intern Med. 2021;36(1):25-31. Published online January 1, 2021
Gallstones account for majority of acute pancreatitis in the Western world. Increase in number and smaller size of the stones increases the risk for biliary pancreatitis. In addition to features of acute pancreatitis, these patients also have cholestatic clinical picture. Fluid therapy and enteral n..
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Rapid Communication / Brief Communication
Dynamics of viral load and anti-SARS-CoV-2 antibodies in patients with positive RT-PCR results after recovery from COVID-19
Kyoung-Ho Song, Dong-Min Kim, Hyunju Lee, Sin Young Ham, Sang-Min Oh, Hyeonju Jeong, Jongtak Jung, Chang Kyung Kang, Ji Young Park, Yu Min Kang, Ji-Yeon Kim, Jeong Su Park, Kyoung Un Park, Eu Suk Kim, Hong Bin Kim
Korean J Intern Med. 2021;36(1):11-14. Published online November 25, 2020
Recently, the number of patients with coronavirus disease 2019 (COVID-19) who have tested positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), via the reverse transcription polymerase chain reaction (RT-PCR) test, after recovery has increased; this has caused a dilemma regardin..
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Rheumatology / Original Article
Pilot study: asymptomatic hyperuricemia patients with obesity and nonalcoholic fatty liver disease have increased risk of double contour sign
Hong Ki Min, Hyonjoung Cho, Sung-Hwan Park
Korean J Intern Med. 2020;35(6):1517-1523. Published online June 13, 2019
Background/Aims: Double contour sign (DCS) is a representative ultrasonographic finding in gout. DCS is evidence of monosodium urate deposit in gouty arthritis and has been identified in some patients with asymptomatic hyperuricemia. However, the specific characteristics of asymptomatic hyperuricemi..
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Hemato-oncology / Original Article
Clinical outcome and predictive factors for docetaxel and epirubicin neoadjuvant chemotherapy of locally advanced breast cancer
Hye Sung Won, Yong Seok Kim, Jeong Soo Kim, Eun Deok Chang, Sae Jung Na, In Yong Whang, Dong Soo Lee
Korean J Intern Med. 2020;35(6):1489-1496. Published online February 21, 2020
Background/Aims: We evaluated the efficacy of docetaxel and epirubicin as neoadjuvant chemotherapy in locally advanced breast cancer and assessed the predictive factors for response to neoadjuvant chemotherapy and prognostic factors related to relapse-free survival.
Methods: Forty patients who rece..
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Hemato-oncology / Original Article
Derivation and validation of modified early warning score plus SpO2/FiO2 score for predicting acute deterioration of patients with hematological malignancies
Ju-Ry Lee, Youn-Kyoung Jung, Hwa Jung Kim, Younsuck Koh, Chae-Man Lim, Sang-Bum Hong, Jin Won Huh
Korean J Intern Med. 2020;35(6):1477-1488. Published online March 3, 2020
Background/Aims: Scoring systems play an important role in predicting intensive care unit (ICU) admission or estimating the risk of death in critically ill patients with hematological malignancies. We evaluated the modified early warning score (MEWS) for predicting ICU admissions and in-hospital mor..
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Hemato-oncology / Original Article
Impact of subsequent chemotherapy on the survival of elderly patients with extensive stage small cell lung cancer
Eun Joo Kang, Yoon Ji Choi, Se Ryeon Lee, Hwa Jung Sung, Jung Sun Kim
Korean J Intern Med. 2020;35(6):1468-1476. Published online April 29, 2020
Background/Aims: The prognosis of small cell lung cancer (SCLC) is still poor because of rapid recurrence, despite good response to initial chemotherapy. Additionally, patients’ old ages and comorbidities are often obstacles that make it difficult to apply subsequent treatment after initial treatm..
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Nephrology / Original Article
Characteristics of kidney transplantation recipients over time in South Korea
Sehoon Park, Myoungsuk Kim, Ji Eun Kim, Kwangsoo Kim, Minsu Park, Yong Chul Kim, Kwon Wook Joo, Yon Su Kim, Hajeong Lee
Korean J Intern Med. 2020;35(6):1457-1467. Published online March 30, 2020
Background/Aims: Detailed nationwide information regarding the recent status and time trends of kidney transplantation (KT) in South Korea is limited.
Methods: We performed a nationwide, population-based cohort study using the national claims database of Korea. We included KT recipients from 2008 t..
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Cardiology / Original Article
Fimasartan, an angiotensin II receptor antagonist, ameliorates an in vivo zebrafish model of heart failure
Hailian Quan, Gyu Chul Oh, Seung Hyeok Seok, Hae-Young Lee
Korean J Intern Med. 2020;35(6):1400-1410. Published online March 13, 2020
Background/Aims: Angiotensin II in the failing heart initially helps to maintain cardiac output and blood pressure, but ultimately accelerates its deterioration. In this study, we established a model of arrhythmia-induced heart failure (HF) in zebrafish and investigated the role of renin-angiotensi..
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Gastroenterology / Original Article
Effect of calcineurin inhibitor on post-endoscopic retrograde cholangiopancreatography pancreatitis in patients with liver transplantation: a propensity-matched cohort study
Hyoung-Chul Oh, Jeffrey J. Easler, Ihab I. El Hajj, James Watkins, Evan L. Fogel, Lee McHenry, Stuart Sherman, Hyun Kang, Glen A. Lehman
Korean J Intern Med. 2020;35(6):1364-1370. Published online February 19, 2020
Background/Aims: A calcineurin inhibitor may alter pancreatic function and inflammatory reaction. This study aimed to determine the possible pharmacologic effect of the calcineurin inhibitor, tacrolimus, on pancreatic function, and to determine its preventive effect on post-endoscopic retrograde cho..
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Gastroenterology / Original Article
Correlation of the grade of hepatic steatosis between controlled attenuation parameter and ultrasound in patients with fatty liver: a multi-center retrospective cohort study
Jeong-Ju Yoo, Yang Jae Yoo, Woo Ram Moon, Seung Up Kim, Soung Won Jeong, Ha Na Park, Min Gyu Park, Jae Young Jang, Su Yeon Park, Beom Kyung Kim, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Kwang-Hyub Han, Sang Gyune Kim, Young Seok Kim, Ji Hoon Kim, Jong Eun Yeon, Kwan Soo Byun
Korean J Intern Med. 2020;35(6):1346-1353. Published online November 8, 2019
Background/Aims: The controlled attenuation parameter (CAP), based on transient elastography, is widely used for noninvasive assessment of the degree of hepatic steatosis (HS). We investigated the correlation of the degree HS between CAP and ultrasound (US) in patients with HS.
Methods: In total, 9..
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Gastroenterology / Original Article
Continuous infusion versus intermittent bolus injection of propofol during endoscopic retrograde cholangiopancreatography
Jae Gon Lee, Kyo-Sang Yoo, Young Jae Byun
Korean J Intern Med. 2020;35(6):1338-1345. Published online March 5, 2020
Background/Aims: It is unclear whether continuous infusion or intermittent bolus injection of propofol is better for achieving adequate sedation in endoscopic retrograde cholangiopancreatography (ERCP). We aimed to compare the efficacy and safety of continuous infusion and intermittent bolus injecti..
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Geriatrics / Original Article
Sarcopenia is associated with severe erectile dysfunction in older adults: a population-based cohort study
Hyungchul Park, Il-Young Jang, Minkyu Han, Heayon Lee, Hee-Won Jung, Eunju Lee, Dae Hyun Kim
Korean J Intern Med. 2020;35(5):1245-1253. Published online April 21, 2020
Background/Aims: Sarcopenia and erectile dysfunction (ED) are associat ed with poor health and quality of life in older men. We investigate the association between sarcopenia and severe ED in community-dwelling older men.
Methods: We prospectively assessed sarcopenia and ED in 519, community-dwelli..
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Hemato-oncology / Original Article
Strong association between herpes simplex virus-1 and chemotherapy-induced oral mucositis in patients with hematologic malignancies
Junshik Hong, Hee-Kyung Park, Suhyun Park, Ahreum Lee, Yeon-Hee Lee, Dong-Yeop Shin, Youngil Koh, Ji-Yeob Choi, Sung-Soo Yoon, Youngnim Choi, Inho Kim
Korean J Intern Med. 2020;35(5):1188-1198. Published online September 9, 2019
Background/Aims: A link between oral cavity infections and chemotherapy-induced oral mucositis (CIOM) in patients with hematological malignancies (HMs) undergoing intensive chemotherapy (IC) or hematopoietic stem cell transplantation (HSCT) has been suggested. However, conclusive data are lacking, a..
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Endocrinology-metabolism / Original Article
The clinical meaning of pre- and post-ablation thyroglobulin levels at first radioiodine therapy in patients with papillary thyroid cancer
Hee Kyung Kim, Jee Hee Yoon, Jin Seong Cho, Seong Young Kwon, Su Woong Yoo, Ho-Cheol Kang
Korean J Intern Med. 2020;35(5):1164-1172. Published online July 29, 2019
Background/Aims: This study was conducted to identify prognostic factors in patients with papillary thyroid cancer (PTC) at the time of first radioactive iodine (RAI) therapy, and to evaluate the clinical value of the thyroglobulin (Tg) increase after RAI.
Methods: Serum Tg was sampled prior to (pr..
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Pulmonology / Original Article
Changes in chest X-ray findings in 1- and 2-month group after treatment initiation for suspected pulmonary tuberculosis
Jang Ho Lee, Ock-Hwa Kim, Yeon Joo Kim, Tae Sun Shim, Kyung-Wook Jo
Korean J Intern Med. 2020;35(5):1145-1153. Published online February 18, 2020
Background/Aims: Although re-evaluation of radiographic follow-up after 2 to 3 months of therapy is recommended for patients administered anti-tuberculosis medication owing to suspected pulmonary tuberculosis, reported findings are limited. Therefore, this study aimed to investigate changes in 1- an..
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Cardiology / Original Article
Left ventricular response after cardiac resynchronization therapy is related to early left atrial volume reduction
In-Jeong Cho, Jae-Sun Uhm, Jaewon Oh, Jong-Ho Nam, Hee Tae Yu, Taehoon Kim, Boyoung Joung, Seok-Min Kang
Korean J Intern Med. 2020;35(5):1125-1135. Published online February 6, 2020
Background/Aims: The current study aimed to elucidate a time-course change in left atrial volume after cardiac resynchronization therapy (CRT) and to verify factors associated with left atrial volume reduction (LAVR) and its prognostic implications.
Methods: The records of 97 patients were retrospe..
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