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Nephrology / Review
New therapeutic agents in diabetic nephropathy
Yaeni Kim, Cheol Whee Park
Korean J Intern Med. 2017;32(1):11-25. Published online January 1, 2017
Studies investigating diabetic nephropathy (DN) have mostly focused on interpreting the pathologic molecular mechanisms of DN, which may provide valuable tools for early diagnosis and prevention of disease onset and progression. Currently, there are few therapeutic drugs for DN, which mainly consist..
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Endocrinology-metabolism / Review
Application of photodynamic therapy in gastrointestinal disorders: an outdated or re-emerging technique?
Han Hee Lee, Myung-Gyu Choi, Tayyaba Hasan
Korean J Intern Med. 2017;32(1):1-10. Published online January 1, 2017
Photodynamic therapy (PDT) is a promising therapeutic modality that involves the administration of a photosensitizer followed by local illumination with a specific wavelength of light in the presence of oxygen. PDT is minimally invasive, has high selectivity for cancer, and has good patient complian..
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Letter to the editor
Expressive aphasia as the manifestation of hyperglycemic crisis in type 2 diabetes
Ji Hyun Lee, Ye An Kim, Joon Ho Moon, Se Hee Min, Young Shin Song, Sung Hee Choi
Korean J Intern Med. 2016;31(6):1187-1190. Published online March 12, 2016
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Letter to the editor
Sporadic medullary microcarcinoma in a male patient with concurrent Hashimoto’s hypothyroidism and Kikuchi disease
Mi-Rim Choi, Seol-Bong Yoo, Ji Hye Kim
Korean J Intern Med. 2016;31(6):1184-1186. Published online January 28, 2016
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Letter to the editor
Hepatocellular carcinoma hidden by multiple infarcted regenerative nodules
Jin Ah Kim, Hye Sung Ahn, Haneul Park, Yoo Rim Seo, Ju Hyun Seo, Chang Wook Kim, Hee Yeon Kim
Korean J Intern Med. 2016;31(6):1178-1180. Published online February 18, 2016
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Cardiology / Original Article
Blood count parameters can predict the severity of coronary artery disease
Hilal Bektas Uysal, Bekir Dağlı, Cağdaş Akgüllü, Mücahit Avcil, Cemil Zencir, Mediha Ayhan, Hulki Meltem Sönmez
Korean J Intern Med. 2016;31(6):1093-1100. Published online April 7, 2016
Background/Aims: Because of the inflammatory nature of coronary artery disease (CAD), both platelets and white blood cells have been investigated for years. The aim of this study was to investigate the relationships between some prominently hematologic blood count parameters (mean platelet volume [M..
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Gastroenterology / Original Article
Ten-year experience of esophageal endoscopic submucosal dissection of superficial esophageal neoplasms in a single center
Hyung Chul Park, Do Hoon Kim, Eun Jeong Gong, Hee Kyong Na, Ji Yong Ahn, Jeong Hoon Lee, Kee Wook Jung, Kee Don Choi, Ho June Song, Gin Hyug Lee, Hwoon-Yong Jung, Jin-Ho Kim
Korean J Intern Med. 2016;31(6):1064-1072. Published online September 13, 2016
Background/Aims: Endoscopic submucosal dissection (ESD) of a superficial esophageal neoplasm (SEN) is a technically difficult procedure. We investigated the clinical outcomes of ESD to determine its feasibility and effectiveness for the treatment of SEN.
Methods: Patients who underwent ESD for SEN ..
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Hemato-oncology / Review
Assessment of bone marrow involvement in patients with lymphoma: report on a consensus meeting of the Korean Society of Hematology Lymphoma Working Party
Yong Park, Byung Bae Park, Ji Yun Jeong, Wook Youn Kim, Seongsoo Jang, Bong Kyung Shin, Dong Soon Lee, Jae Ho Han, Chan-Jeoung Park, Cheolwon Suh, Insun Kim, Hyun-Sook Chi
Korean J Intern Med. 2016;31(6):1030-1041. Published online November 1, 2016
In September 2011, the Korean Society of Hematology Lymphoma Working Party held a nationwide conference to establish a consensus for assessing bone marrow (BM) involvement in patients with lymphoma. At this conference, many clinicians, hematopathologists, and diagnostic hematologists discussed vario..
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Letter to the editor
Angiographic spontaneous pseudo-resolution of a coronary artery aneurysm after implantation of a sirolimus-eluting stent
Yong-Woo Choi, Hong-Seok Lim, Seung-Jea Tahk, Myeong-Ho Yoon, Hyoung-Mo Yang, Xiong-Jie Jin
Korean J Intern Med. 2016;31(5):987-990. Published online January 28, 2016
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Infectious diseases / Original Article
Differences of cytomegalovirus diseases between kidney and hematopoietic stem cell transplant recipients during preemptive therapy
Tark Kim, Yu-Mi Lee, Sang-Oh Lee, Sang-Ho Choi, Yang Soo Kim, Jun Hee Woo, Heungsup Sung, Joo Hee Jung, Sung Shin, Young Hoon Kim, Young-Ah Kang, Young-Shin Lee, Jung-Hee Lee, Je-Hwan Lee, Kyoo-Hyung Lee, Su-Kil Park, Duck Jong Han, Sung-Han Kim
Korean J Intern Med. 2016;31(5):961-970. Published online April 8, 2016
Background/Aims: Cytomegalovirus (CMV) surveillance and preemptive therapy is a widely-used strategy for preventing CMV disease in transplant recipients. However, there are limited data on the incidence and patterns of CMV disease during the preemptive period. Thus, we investigated the incidence and..
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Hemato-oncology / Original Article
Clinical manifestations of autoimmune disease-related non-Hodgkin lymphoma: a Korean single-center, retrospective clinical study
Young-Woo Jeon, Jae-Ho Yoon, Sung-Eun Lee, Ki-Seong Eom, Yoo-Jin Kim, Hee-Je Kim, Seok Lee, Chang-Ki Min, Jong Wook Lee, Woo-Sung Min, Seok-Goo Cho
Korean J Intern Med. 2015;31(5):944-952. Published online July 7, 2016
Background/Aims: Recently, large cohort studies regarding associations between autoimmune disease and lymphomas have been reported in a few Western countries. However, Asian data concerning autoimmune-related lymphomas are limited. Therefore, we evaluated the clinical characteristics and prognostic ..
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Nephrology / Original Article
Urine synaptopodin excretion is an important marker of glomerular disease progression
Soon Kil Kwon, Seung Jung Kim, Hye-Young Kim
Korean J Intern Med. 2016;31(5):938-943. Published online September 1, 2016
Background/Aims: Podocytes play an important role in maintaining the glomerular filtration barrier and in formation of the slit diaphragm. Podocyte loss is associated with chronic kidney disease progression, but it is not clear whether urinary podocyte proteins in urine reflect the clinical extent o..
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Pulmonology / Original Article
Usefulness of neutrophil to lymphocyte ratio in patients with chronic obstructive pulmonary
disease: a prospective observational study
Seung Jun Lee, Hyang Rae Lee, Tae Won Lee, Sunmi Ju, Sujin Lim, Se-Il Go, Jung-Wan You, Yu Ji Cho, Gyeong-Won Lee, Yi Yeong Jeong, Ho Cheol Kim, Jong Deog Lee
Korean J Intern Med. 2016;31(5):891-898. Published online March 25, 2016
Background/Aims: Neutrophil to lymphocyte ratio (NLR) in peripheral blood is a useful systemic inflammatory response biomarker. However, NLR has not been studied in patients with chronic obstructive pulmonary disease (COPD). This study was aimed to evaluate the usefulness of NLR in patients with COP..
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Cardiology / Original Article
Prognostic value of computed tomographic coronary angiography and exercise electrocardiography for cardiovascular events
Kye-Hwan Kim, Kyung Nyeo Jeon, Min Gyu Kang, Jong Hwa Ahn, Jin-Sin Koh, Yongwhi Park, Seok-Jae Hwang, Young-Hoon Jeong, Choong Hwan Kwak, Jin-Yong Hwang, Jeong Rang Park
Korean J Intern Med. 2016;31(5):880-890. Published online March 25, 2016
Background/Aims: This study is a head-to-head comparison of predictive values for long-term cardiovascular outcomes between exercise electrocardiography (ex-ECG) and computed tomography coronary angiography (CTCA) in patients with chest pain.
Methods: Four hundred and forty-two patients (mean age, ..
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Gastroenterology / Original Article
Comparison of intraductal ultrasonography-directed and cholangiography-directed endoscopic retrograde biliary drainage in patients with a biliary obstruction
Soo-Jung Rew, Du-Hyeon Lee, Chang-Hwan Park, Jin Jeon, Hyun-Soo Kim, Sung-Kyu Choi, Jong-Sun Rew
Korean J Intern Med. 2016;31(5):872-879. Published online April 21, 2016
Background/Aims: Endoscopic retrograde biliary drainage (ERBD) has become a standard procedure in patients with a biliary obstruction. Intraductal ultrasonography (IDUS) has emerged as a new tool for managing extrahepatic biliary diseases. IDUS-directed ERBD can be performed without conventional cho..
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Review
Endoscopic gastritis, serum pepsinogen assay, and Helicobacter pylori infection
Sun-Young Lee
Korean J Intern Med. 2016;31(5):835-844. Published online September 1, 2016
Endoscopic findings of the background gastric mucosa are important in the Helicobacter pylori-seroprevalent population. It is strongly correlated not only with the risk of gastric cancer, but also with the excretion ability of gastric mucosa cells. In noninfected subjects, common endoscopic f..
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Letter to the editor
A rare case of Rosai-Dorfman disease without lymphadenopathy
Hyerim Ha, Ki Hwan Kim, Young Joon Ahn, Ji Hye Kim, Ji Eun Kim, Sung-Soo Yoon
Korean J Intern Med. 2016;31(4):802-804. Published online February 2, 2016
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Letter to the editor
Urachal abscess precipitated as acute pyelonephritis in an adult patient with diabetes
Yoo A Choi, Se Young Kim, Kyung Yoon Chang, Hyeon Seok Hwang, Suk Young Kim, Yoon Kyung Chang
Korean J Intern Med. 2016;31(4):798-801. Published online January 28, 2016
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Letter to the editor
Intermittent, subtle change of ST segment in narrow QRS regular tachycardia
Hyeong Won Seo, Hyung Wook Park, Ki Hong Lee, Joon-Ho Ahn, Ji Eun Yu, Nam Sik Yoon, Jeong Gwan Cho
Korean J Intern Med. 2016;31(4):791-793. Published online June 17, 2016
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Infectious diseases / Original Article
Diagnostic yield of computed tomography-guided bone biopsy and clinical outcomes of tuberculous and pyogenic spondylitis
Eun-Jeong Joo, Joon-Sup Yeom, Young Eun Ha, So Yeon Park, Chong-Suh Lee, Eun-Sang Kim, Cheol-In Kang, Doo-Ryeon Chung, Jae-Hoon Song, Kyong Ran Peck
Korean J Intern Med. 2016;31(4):762-771. Published online April 15, 2016
Background/Aims: This study aimed to evaluate the efficacy of computed tomography (CT)-guided bone biopsy for the diagnosis of spinal infection and compared the clinical outcomes between tuberculous and pyogenic spinal infections.
Methods: The retrospective cohort study included patients who receiv..
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