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Gastroenterology / Original Article
Outcome of donor biliary complications following living donor liver transplantation
Hyun Young Woo, In Seok Lee, Jae Hyuck Chang, Seung Bae Youn, Si Hyun Bae, Jong Young Choi, Ho Jong Chun, Young Kyoung You, Dong Goo Kim, Seung Kew Yoon
Korean J Intern Med. 2018;33(4):705-715. Published online March 14, 2018
Background/Aims: Biliary complications are the most common donor complication following living donor liver transplantation (LDLT). The aim of this study is to investigate the long-term outcomes of biliary complications in right lobe adult-to-adult LDLT donors, and to evaluate the efficacy of endosco..
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Hemato-oncology / Review
Recent advances in the diagnosis and management of primary myelofibrosis
Katsuto Takenaka, Kazuya Shimoda, Koichi Akashi
Korean J Intern Med. 2018;33(4):679-690. Published online April 20, 2018
Primary myelofibrosis (PMF) is a myeloproliferative neoplasm (MPN) in which dysregulation of the Janus kinase/signal transducers and activators of transcription (JAK/STAT) signaling pathways is the major pathogenic mechanism. Most patients with PMF carry a driver mutation in the JAK2, MPL (my..
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Nephrology / Review
Applications of kidney organoids derived from human pluripotent stem cells
Yong Kyun Kim, Sun Ah Nam, Chul Woo Yang
Korean J Intern Med. 2018;33(4):649-659. Published online June 28, 2018
The establishment of protocols to differentiate kidney organoids from human pluripotent stem cells provides potential applications of kidney organoids in regenerative medicine. Modeling of renal diseases, drug screening, nephrotoxicity testing of compounds, and regenerative therapy are attractive ap..
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Letter to the editor
Loeffler endocarditis in chronic eosinophilic leukemia with FIP1L1/PDGFRA rearrangement: full recovery with low dose imatinib
Dae Sik Kim, Sunki Lee, Chul Won Choi
Korean J Intern Med. 2018;33(3):642-644. Published online June 28, 2017
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Letter to the editor
Multiple metastasis of follicular variant of papillary thyroid carcinoma coexistent with malignant melanoma
Yu Ji Kim, Kyung Ae Lee, Tae Sun Park, Hong Sun Baek, Heung Yong Jin
Korean J Intern Med. 2018;33(3):634-637. Published online January 16, 2017
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Cardiology / Original Article
Prognostic value of total triiodothyronine and free thyroxine levels for the heart failure in patients with acute myocardial infarction
Min Gyu Kang, Jong Ryeal Hahm, Kye-Hwan Kim, Hyun-Woong Park, Jin-Sin Koh, Seok-Jae Hwang, Jin-Yong Hwang, Jong Hwa Ahn, Yongwhi Park, Young-Hoon Jeong, Jeong Rang Park, Choong Hwan Kwak
Korean J Intern Med. 2018;33(3):512-521. Published online January 11, 2017
Background/Aims: Although a low triiodothyronine (T3) state is closely associated with heart failure (HF), it is uncertain whether total T3 levels on admission is correlated with the clinical outcomes of acute myocardial infarction (AMI). The aim of this study is to investigate the prognostic value..
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Cardiology / Review
Expanding transcatheter aortic valve replacement into uncharted indications
Guson Kang, Juyong Brian Kim
Korean J Intern Med. 2018;33(3):474-482. Published online March 20, 2018
Since the first-in-man transcatheter delivery of an aortic valve prosthesis in 2002, the landscape of aortic stenosis therapeutics has shifted dramatically. While initially restricted to non-surgical cases, progressive advances in transcatheter aortic valve replacement and our understanding of its s..
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Letter to the editor
Dasatinib induces severe hemorrhagic colitis in a patient with accelerated phase of chronic myelogenous leukemia
Eunjung Yim, Yeon-Geun Choi, Yoon-Jeong Nam, Jain Lee, Jeong-A Kim
Korean J Intern Med. 2018;33(2):446-448. Published online March 10, 2016
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Letter to the editor
Synchronous diffuse large B-cell lymphoma of the small intestine and adenocarcinoma of the colon
Ji Hyun Yang, Jain Lee, Shin Bum Kim, Seon Hoo Kim, Guk Jin Lee
Korean J Intern Med. 2018;33(2):438-441. Published online November 10, 2017
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Infectious diseases / Original Article
Late diagnosis of influenza in adult patients during a seasonal outbreak
Seong-Ho Choi, Jin-Won Chung, Tark Kim, Ki-Ho Park, Mi Suk Lee, Yee Gyung Kwak
Korean J Intern Med. 2018;33(2):391-396. Published online November 10, 2017
Background/Aims: Due to advances in diagnostic techniques, clinicians are more frequently performing influenza diagnostic tests and referring to their test results ahead of the administration of neuraminidase inhibitors (NAIs). To investigate the clinical significance of the time from symptom onset ..
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Hemato-oncology / Original Article
Retrospective analysis of palliative chemotherapy for the patients with bladder adenocarcinoma: Korean Cancer Study Group Genitourinary and Gynecology Cancer Committee
Moon Jin Kim, Young Sam Kim, Sung Yong Oh, Suee Lee, Young-Jin Choi, Young Mi Seol, Min Jae Park, Ki Hyang Kim, Lee Chun Park, Jung Hun Kang, In-Gyu Hwang, Soon Il Lee, Seung Taek Lim, Hyo Song Kim, Ho Yeong Lim, Sun Young Rha, Hyo-Jin Kim
Korean J Intern Med. 2018;33(2):383-390. Published online April 6, 2016
Background/Aims: Because of rarity, role of chemotherapy of bladder adenocarcinoma are still unidentified. Therefore, we performed a retrospective analysis of the clinical features and chemotherapy outcomes of bladder adenocarcinoma.
Methods: Eligible patients for this retrospective analysis were i..
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Nephrology / Original Article
Outcomes of living donor kidney transplantation in diabetic patients: age and sex matched comparison with non-diabetic patients
Chung Hee Baek, Hyosang Kim, Seung Don Baek, Mun Jang, Wonhak Kim, Won Seok Yang, Duck Jong Han, Su-Kil Park
Korean J Intern Med. 2018;33(2):356-366. Published online August 21, 2017
Background/Aims: Kidney transplantation (KT) reportedly provides a significant survival advantage over dialysis in diabetic patients. However, KT outcome in diabetic patients compared with that in non-diabetic patients remains controversial. In addition, owing to recent improvements in the outcomes ..
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Endocrinology-metabolism / Original Article
Compound K attenuates glucose intolerance and hepatic steatosis through AMPK-dependent pathways in type 2 diabetic OLETF rats
Yoo-Cheol Hwang, Da-Hee Oh, Moon Chan Choi, Sang Yeoul Lee, Kyu-Jeong Ahn, Ho-Yeon Chung, Sung-Jig Lim, Sung Hyun Chung, In-Kyung Jeong
Korean J Intern Med. 2018;33(2):347-355. Published online February 1, 2017
Background/Aims: Non-alcoholic fatty liver disease is associated with insulin resistance. Compound K (CK) is the final metabolite of panaxadiol ginsenosides that have been shown to exert antidiabetic effects. However, the molecular mechanism of the antidiabetic effects in the liver have not been elu..
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Pulmonology / Original Article
Computed tomography morphologic features of pulmonary adenocarcinoma with brain/bone metastasis
Ki-Eun Hwang, Su-Jin Oh, Chul Park, Se-Jeong Jeon, Jeong-Mi Lee, Byong-Ki Cha, Kwon-Ha Yoon, Eun-Taik Jeong, Hak-Ryul Kim
Korean J Intern Med. 2018;33(2):340-346. Published online February 15, 2017
Background/Aims: Brain and bone metastases are common in patients with lung cancer. The development of metastasis is associated with poor survival in lung cancer patients. Although tumor morphologic features on radiographs are routinely assessed for differentiation between benign and malignant lung ..
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Pulmonology / Original Article
Comparison of clinical utility between diaphragm excursion and thickening change using ultrasonography to predict extubation success
[corrected-article]
Jung-Wan Yoo, Seung Jun Lee, Jong Deog Lee, Ho Cheol Kim
Korean J Intern Med. 2018;33(2):331-339. Published online October 19, 2017
Background/Aims: Both diaphragmatic excursion and change in muscle thickening are measured using ultrasonography (US) to assess diaphragm function and mechanical ventilation weaning outcomes. However, which parameter can better predict successful extubation remains to be determined. The aim of this ..
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Infectious diseases / Review
Infectious complications after hematopoietic stem cell transplantation: current status and future perspectives in Korea
Sung-Yeon Cho, Hyeon-Jeong Lee, Dong-Gun Lee
Korean J Intern Med. 2018;33(2):256-276. Published online February 27, 2018
Hematopoietic stem cell transplantation (HSCT) is a treatment for hematologic malignancies, immune deficiencies, or genetic diseases, ect. Recently, the number of HSCTs performed in Korea has increased and the outcomes have improved. However, infectious complications account for most of the morbidit..
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Letter to the editor
Invasive pulmonary aspergillosis in a patient with metastatic non-small cell lung cancer after
treatment with gefitinib
Sejeong Park, Soyoung Park, Hana Choi, Ji Young Park, Hyo Seok Lim, Myung Jae Park, Si-Young Kim
Korean J Intern Med. 2018;33(1):211-213. Published online November 25, 2016
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Allergy / Original Article
Disease-specific impairment of the quality of life in adult patients with chronic spontaneous urticaria
Won-Sun Choi, Eun-Soo Lim, Ga-Young Ban, Ji-Hye Kim, Yoo-Seob Shin, Hae-Sim Park, Young-Min Ye
Korean J Intern Med. 2018;33(1):185-192. Published online June 1, 2016
Background/Aims: Chronic urticaria (CU) is a common skin disorder characterized by wheals and pruritus lasting more than 6 weeks. Due to its long duration and changeable symptoms, the quality of life (QOL) of patients with CU can be impaired substantially. We evaluated the CU-QOL, a previously valid..
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Infectious diseases / Original Article
Clinical value of procalcitonin for suspected nosocomial bloodstream infection
Joo Kyoung Cha, Ki Hwan Kwon, Seung Joo Byun, Soo Ryeong Ryoo, Jeong Hyeon Lee, Jae-Woo Chung, Hee Jin Huh, Seok Lae Chae, Seong Yeon Park
Korean J Intern Med. 2018;33(1):176-184. Published online November 8, 2017
Background/Aims: Procalcitonin (PCT) may prove to be a useful marker to exclude or predict bloodstream infection (BSI). However, the ability of PCT levels to differentiate BSI from non-BSI episodes has not been evaluated in nosocomial BSI.
Methods: We retrospectively reviewed the medical records of..
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Hemato-oncology / Original Article
Epidermal growth factor receptor mutation and pattern of brain metastasis in patients with non-small cell lung cancer
Min Young Baek, Hee Kyung Ahn, Kyu Ree Park, Hwa-Sun Park, Shin Myung Kang, Inkeun Park, Young Saing Kim, Junshik Hong, Sun Jin Sym, Jinny Park, Jae Hoon Lee, Dong Bok Shin, Eun Kyung Cho
Korean J Intern Med. 2018;33(1):168-175. Published online April 20, 2016
Background/Aims: We investigated the time taken for patients with metastatic non-small cell lung cancer (NSCLC) to develop brain metastases (BM), as well as their subsequent overall median survival following diagnosis, considering the epidermal growth factor receptor (EGFR) mutational status...
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