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Nephrology / Original Article
Clinical significance of the presence of anti-human leukocyte antigen-donor specific antibody
in kidney transplant recipients with allograft dysfunction
Byung Ha Chung, Jeong Ho Kim, Bum Soon Choi, Cheol Whee Park, Ji-Il Kim, In Sung Moon, Yong-Soo Kim, Yeong Jin Choi, Eun-Jee Oh, Chul Woo Yang
Korean J Intern Med. 2018;33(1):157-167. Published online October 20, 2016
Background/Aims: This study investigated the clinical significance of detecting anti-human leukocyte antigen-donor specific antibody (HLA-DSA) in kidney transplant recipients (KTRs) requiring indication biopsy owing to allograft dysfunction.
Methods: We analyzed the presence of HLA-DSA in 210 KTRs ..
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Nephrology / Original Article
Long-term prognosis of end-stage renal disease patients with normal myocardial perfusion as determined by single photon emission computed tomography
Gun Ha Park, Jae Won Song, Chang Min Lee, Young Rim Song, Sung Gyun Kim, Hyung Jik Kim, Jwa Kyung Kim
Korean J Intern Med. 2018;33(1):148-156. Published online November 22, 2016
Background/Aims: Normal myocardial perfusion is closely associated with very low rates of cardiac events and better long-term outcomes; however, little is known about its prognostic value in patients with end-stage renal disease (ESRD).
Methods: A total of 286 incident patients underwent baseline c..
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Cardiology / Original Article
Diagnostic accuracy of manual office blood pressure measurement in ambulatory hypertensive patients in Korea
Sehun Kim, Jin Joo Park, Seung-Ah Lee, Youngjin Cho, Yeonyee E. Yoon, Il-Young Oh, Chang-Hwan Yoon, Jung-Won Suh, Young-Seok Cho, Tae-Jin Youn, Goo-Yeong Cho, In-Ho Chae, Hae-Young Lee, Jinho Shin, Sungha Park, Dong-Ju Choi
Korean J Intern Med. 2018;33(1):113-120. Published online June 7, 2017
Background/Aims: Currently, office blood pressure (OBP) is the most widely used method of measuring blood pressure (BP) in daily clinical practice. However, data on the diagnostic accuracy of OBP in reference to ambulatory blood pressure (ABP) are scarce in Korea.
Methods: In retrospective and prospec..
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Cardiology / Original Article
Risk factors for poor prognosis in nosocomial infective endocarditis
Ji-won Hwang, Seung Woo Park, Eun Jeong Cho, Ga Yeon Lee, Eun Kyoung Kim, Sung-A Chang, Sung-Ji Park, Sang-Chol Lee, Cheol-In Kang, Doo Ryeon Chung, Kyong Ran Peck, Jae-Hoon Song
Korean J Intern Med. 2018;33(1):102-112. Published online June 2, 2017
Background/Aims: The aim of our study was to compare the characteristics of nosocomial infective endocarditis (NIE) with community-acquired infective endocarditis (CIE) and to determine independent risk factors for in-hospital death.
Methods: We retrospectively reviewed the medical records of 560 ..
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Gastroenterology / Original Article
Infection of human intestinal epithelial cells by invasive bacteria activates NF-κB and increases ICAM-1 expression through NOD1
Woon Geon Shin, Bum Joon Park, Sung Joong Lee, Jae Gyu Kim
Korean J Intern Med. 2018;33(1):81-90. Published online January 16, 2017
Background/Aims: Nucleotide-binding oligomerization domain 1 (NOD1) is required for primary intestinal epithelial cells (IECs) to respond to natural mucopeptides secreted by gram-negative bacteria. Infection of human IECs with invasive bacteria up-regulates intercellular adhesion molecule-1 (ICAM-1)..
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Gastroenterology / Review
Present status and perspectives of endosonography 2017 in gastroenterology
Michael Hocke, Barbara Braden, Christian Jenssen, Christoph F. Dietrich
Korean J Intern Med. 2018;33(1):36-63. Published online November 23, 2017
Endoscopic ultrasound has become an essential tool in modern gastroenterology and abdominal surgery. Compared with all other endoscopic methods, it has the most potential for innovation and its future looks bright. Thus, we compiled this summary of established and novel applications of endoscopic ul..
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Gastroenterology / Review
Changing treatment paradigms for the management of inflammatory bowel disease
Jong Pil Im, Byong Duk Ye, You Sun Kim, Joo Sung Kim
Korean J Intern Med. 2018;33(1):28-35. Published online December 28, 2017
Inf lammatory bowel disease (IBD) is a chronic and progressive inf lammatory condition of the gastrointestinal tract causing bowel damage, hospitalizations, surgeries, and disability. Although there has been much progress in the management of IBD with established and evolving therapies, most current..
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Letter to the editor
Xp11.2 translocation renal cell carcinoma in the autosomal dominant polycystic kidney disease patient with preserved renal function
Hyuk Huh, Hyung Ah Jo, YongJin Yi, Seung Hyup Kim, Kyung Chul Moon, Curie Ahn, Hayne Cho Park
Korean J Intern Med. 2017;32(6):1108-1111. Published online October 17, 2017
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Rheumatology / Original Article
Nontuberculous mycobacterial infection in rheumatoid arthritis patients: a single-center experience in South Korea
[corrected-article]
Doo-Ho Lim, Yong-Gil Kim, Tae Sun Shim, Kyung-Wook Jo, Byeongzu Ghang, Soo Min Ahn, Seokchan Hong, Chang-Keun Lee, Bin Yoo
Korean J Intern Med. 2017;32(6):1090-1097. Published online January 6, 2017
Background/Aims: Nontuberculous mycobacteria (NTM) infection has been increasing worldwide in both general population and immunocompromised patients, which has also been reported in rheumatoid arthritis (RA) patients. This study aimed to identify the incidence and clinical characteristics of NTM inf..
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Infectious diseases / Original Article
Diagnostic role of mean platelet volume and neutrophil to lymphocyte ratio in childhood brucellosis
Şefika Elmas Bozdemir, Yasemin Ay Altıntop, Salih Uytun, Humeyra Aslaner, Yasemin Altuner Torun
Korean J Intern Med. 2017;32(6):1075-1081. Published online December 14, 2016
Background/Aims: Brucellosis patients present various non-specific clinical symptoms, such as fever, fatigue, sweating, joint pain, arthritis, myalgia, and headache. Based on the nonspecifity of its clinical signs and symtoms, we decided to evaluate whether mean platelet volume (MPV) , neutrophil to..
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Hemato-oncology / Original Article
Analgesic effect of quetiapine in a mouse model of cancer-induced bone pain
Mi Hwa Heo, Jin Young Kim, Ilseon Hwang, Eunyoung Ha, Keon Uk Park
Korean J Intern Med. 2017;32(6):1069-1074. Published online January 20, 2017
Background/Aims: Cancer-induced bone pain (CIBP) is one of the most common pains in patients with advanced neoplasms. Because of treatment-associated side effects, more than half of cancer patients are reported to have inadequate and undermanaged pain control. New mechanism-based therapies must be d..
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Letter to the editor
Hyperglycemic hyperosmolar state associated with invasive rhino-orbital aspergillosis in a
patient with end-stage renal disease
Ju Hyun Seo, Jin Ah Kim, Bomi Choi, Kyo Hee Kim, Ha Neul Park, Hannah Seok, Tae Seo Sohn
Korean J Intern Med. 2017;32(5):936-938. Published online March 10, 2016
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Letter to the editor
Solitary immunoglobulin G4-related inflammatory pseudotumor in the abdomen wall
Yunsuek Kim, Hae Kyung Lee, Gyuhwan Hwang, In Ho Choi, Hyun-Sook Kim
Korean J Intern Med. 2017;32(5):933-935. Published online March 12, 2016
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Letter to the editor
Metronomic chemotherapy with capecitabine for metastatic colorectal cancer in very elderly patients
Yun Hwa Jung, Won Jik Lee, Jae Ho Byeon, In Kyu Lee, Chi Wha Han, In Sook Woo
Korean J Intern Med. 2017;32(5):926-929. Published online March 10, 2016
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Rheumatology / Original Article
Ileocolonoscopic findings in patients with ankylosing spondylitis: a single center retrospective
study
Soo Min Ahn, Yong-Gil Kim, Seung-Hyeon Bae, Doo-Ho Lim, Seokchan Hong, Sang Hyoung Park, Chang-Keun Lee, Bin Yoo
Korean J Intern Med. 2017;32(5):916-922. Published online August 11, 2017
Background/Aims: In some Western countries, up to 50% of patients with ankylosing spondylitis (AS) have subclinical gut inflammation. This study was conducted to evaluate the prevalence and severity of gut inflammation and to determine clinical factors associated with colonic inflammation in Korean ..
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Infectious diseases / Original Article
Clinical applications of interferon-γ releasing assays for cytomegalovirus to differentiate cytomegalovirus disease from bystander activation: a pilot proof-of-concept study
Sung-Han Kim, Ho-Su Lee, Hyun-Jung Lee, Sun-Mi Kim, Sung Shin, Sang-Hyoung Park, Kyung-Jo Kim, Young-Hoon Kim, Heungsup Sung, Sang-Oh Lee, Sang-Ho Choi, Suk-Kyun Yang, Yang Soo Kim, Jun Hee Woo, Duck-Jong Han
Korean J Intern Med. 2017;32(5):900-909. Published online August 23, 2017
Background/Aims: We evaluated the proposed clinical application of the combined interpretation of host factors and viral factors in two different cytomegalovirus (CMV) co-infection models.
Methods: We prospectively enrolled all human immunodeficiency virus non-infected patients with confirmed P..
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Infectious diseases / Review
Voriconazole-refractory invasive aspergillosis
Se Yoon Park, Jung-A Yoon, Sung-Han Kim
Korean J Intern Med. 2017;32(5):805-812. Published online August 24, 2017
Invasive aspergillosis (IA) is one of the most common life-threatening complications in immunocompromised patients. Voriconazole is currently the drug of choice for IA treatment. However, some patients with IA suffer clinical deterioration despite voriconazole therapy. Management of voriconazole-ref..
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Hemato-oncology / Review
Targeted therapy of ovarian cancer including immune check point inhibitor
Jin Young Kim, Chi Heum Cho, Hong Suk Song
Korean J Intern Med. 2017;32(5):798-804. Published online August 22, 2017
Epithelial ovarian cancer is the eighth most common cause of cancer-related deaths in women because most patients present with advanced stage disease at the time of diagnosis. Although cytoreductive surgery and platinum-based chemotherapy remain the gold standards of treatment, the recurrence rate o..
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Nephrology / Review
Pre-existing arterial pathologic changes affecting arteriovenous fistula patency and cardiovascular mortality in hemodialysis patients
Ja Young Lee, Young Ok Kim
Korean J Intern Med. 2017;32(5):790-797. Published online August 22, 2017
The radiocephalic arteriovenous fistula (AVF) provides optimal vascular access for hemodialysis; it has a higher long-term patency rate and fewer complications than other vascular access methods. However, the AVF has a high primary failure rate. The presence of small-diameter vessels at anastomosis ..
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Letter to the editor
Repeated isolated bilateral coronary ostial stenosis related to the syphilitic aortitis
Sang Min Kim, Sang Yeub Lee, Ju-Hee Lee, Jang-Whan Bae, Kyung-Kuk Hwang
Korean J Intern Med. 2017;32(4):747-749. Published online June 26, 2017
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