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Allergy / Original Article
Association of autophagy related gene polymorphisms with neutrophilic airway inflammation in adult asthma
Duy Le Pham, Seung-Hyun Kim, Purevsuren Losol, Eun-Mi Yang, Yoo Seob Shin, Young-Min Ye, Hae-Sim Park
Korean J Intern Med. 2016;31(2):375-385. Published online December 23, 2015
Background/Aims: Role of autophagy in neutrophil function and the association of autophagy and autophagy related (ATG) gene polymorphisms with asthma susceptibility were suggested. In this study, we investigated the genetic association of ATG5 and ATG7 polymorphisms with asthma risk, s..
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Nephrology / Original Article
Effect of low-dose valsartan on proteinuria in normotensive immunoglobulin A nephropathy with minimal proteinuria: a randomized trial
Young-Il Jo, Ha-Young Na, Ju-Young Moon, Sang-Woong Han, Dong-Ho Yang, Sang-Ho Lee, Hyeong-Cheon Park, Hoon-Young Choi, So-Dug Lim, Jeong-Hae Kie, Yong-Kyu Lee, Sug-Kyun Shin
Korean J Intern Med. 2016;31(2):335-343. Published online February 15, 2016
Background/Aims: Immunoglobulin A nephropathy (IgAN) is a generally progressive disease, even in patients with favorable prognostic features. In this study, we aimed to investigate the antiproteinuric effect and tolerability of low-dose valsartan (an angiotensin II receptor blocker) therapy in normo..
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Endocrinology-metabolism / Original Article
Comparison of two- and three-dimensional sonography for the prediction of the extrathyroidal extension of papillary thyroid carcinomas
Yang Seon Yi, Sang Soo Kim, Won Jin Kim, Min Jung Bae, Ji Hyun Kang, Bo Gwang Choi, Yun Kyung Jeon, Bo Hyun Kim, Byung Joo Lee, Soo Geun Wang, In Joo Kim, Yong Ki Kim
Korean J Intern Med. 2016;31(2):313-322. Published online December 23, 2015
Background/Aims: The purpose of this study was to compare the diagnostic validity of two-dimensional (2D) and three-dimensional (3D) ultrasonography (US) when predicting the extrathyroidal extension of papillary thyroid cancer.
Methods: All 2D data were interpreted in real time and 3D data were sto..
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Cardiology / Original Article
Impact of the β-1 adrenergic receptor polymorphism on tolerability and efficacy of bisoprolol therapy in Korean heart failure patients: association between β adrenergic receptor polymorphism and bisoprolol therapy in heart failure (ABBA) study
Hae-Young Lee, Wook-Jin Chung, Hui-Kyung Jeon, Hong-Seog Seo, Dong-Ju Choi, Eun-Seok Jeon, Jae-Joong Kim, Joon Han Shin, Seok-Min Kang, Sung Cil Lim, Sang-Hong Baek
Korean J Intern Med. 2016;31(2):277-287. Published online February 16, 2016
Background/Aims: We evaluated the association between coding region variants of adrenergic receptor genes and therapeutic effect in patients with congestive heart failure (CHF).
Methods: One hundred patients with stable CHF (left ventricular ejection fraction [LVEF] < 45%) were enrolled. Enrolled ..
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Gastroenterology / Original Article
Synchronous second primary cancers in patients with squamous esophageal cancer: clinical features and survival outcome
Jin Seo Lee, Ji Yong Ahn, Kee Don Choi, Ho June Song, Yong Hee Kim, Gin Hyug Lee, Hwoon-Yong Jung, Jin-Sook Ryu, Sung-Bae Kim, Jong Hoon Kim, Seung-Il Park, Kyung-Ja Cho, Jin-Ho Kim
Korean J Intern Med. 2016;31(2):253-259. Published online February 11, 2016
Background/Aims: Unexpected diagnosis of synchronous second primary cancers (SPC) complicates physicians’ decision-making because clinical details of squamous esophageal cancer (EC) patients with SPC have been limited. We evaluated clinical features and treatment outcomes of patients with synchron..
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Letter to the editor
Co-existing proteinase 3-antineutrophil cytoplasmic antibody-associated vasculitis with immunoglobulin A nephropathy
Adem Kucuk, Yalcin Solak, Abduzhappar Gaipov, Sinan Bagcaci, Hasan Esen, Suleyman Turk, Recep Tunc
Korean J Intern Med. 2016;31(1):194-196. Published online December 28, 2015
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Letter to the editor
Churg-Strauss syndrome that presented with mediastinal lymphadenopathy and calculous cholecystitis
Jung Yoon Choi, Ji Eun Kim, In Young Choi, Ju Han Lee, Je Hyeong Kim, Chol Shin, Seung Heon Lee
Korean J Intern Med. 2016;31(1):179-183. Published online December 28, 2015
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Infectious diseases / Original Article
Use of cefuroxime for women with community-onset acute pyelonephritis caused by cefuroxime-susceptible or -resistant Escherichia coli
U-Im Chang, Hyung Wook Kim, Seong-Heon Wie
Korean J Intern Med. 2016;31(1):145-155. Published online December 28, 2015
Background/Aims: Efforts to decrease the use of extended-spectrum cephalosporins are required to prevent the selection and transmission of multi-drug resistant pathogens, such as extended-spectrum b-lactamase (ESBL)-producing Enterobacteriaceae. The objectives of this study were to assess the clinic..
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Gastroenterology / Original Article
Feasibility of α-fetoprotein as a diagnostic tool for hepatocellular carcinoma in Korea
Dae Geon Ahn, Hyung Joon Kim, Hyun Kang, Hyun Woong Lee, Si Hyun Bae, Joon Hyoek Lee, Yong Han Paik, June Sung Lee
Korean J Intern Med. 2016;31(1):46-53. Published online December 28, 2015
Background/Aims: The aim of this study was to evaluate the feasibility of α-fetoprotein (AFP) as a diagnostic tool for hepatocellular carcinoma (HCC) in Korean patients.
Methods: We retrospectively reviewed the medical records of HCC and cirrhosis patients at three hospitals. For each HCC patient..
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Letter to the editor
Takayasu arteritis and antiphospholipid antibody syndrome in an elderly woman
Hee-Jeong Lee, Jae Pil Hwang, Hyun-Sook Kim
Korean J Intern Med. 2015;30(6):934-937. Published online October 30, 2015
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Letter to the editor
Long-term survival after concurrent chemoradiation therapy for esophageal cancer with tracheal
invasion
Joon Hyun Cho, Tae Nyeun Kim
Korean J Intern Med. 2015;30(6):931-933. Published online October 30, 2015
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Letter to the editor
Fabry disease previously diagnosed as Henoch-Schonlein purpura
Ji Hyeong Kim, Dong Hoon Han, Moo Yong Park, Soo Jeong Choi, Jin Kuk Kim, Seung Duk Hwang, So Young Jin
Korean J Intern Med. 2015;30(6):925-927. Published online October 30, 2015
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Nephrology / Original Article
The effects of nonyl phenoxypolyethoxyl ethanol on cell damage pathway gene expression in SK-NSH cells
Samel Park, Il-woong Hwang, Jin-sheon Kim, Hyo-chul Kang, Su-Yeon Park, Hyo-wook Gil, Ho-yeon Song, Sae-yong Hong
Korean J Intern Med. 2015;30(6):873-883. Published online October 30, 2015
Background/Aims: Most pesticide formulations contain both chief and additive ingredients. But, the additives may not have been tested as thoroughly as the chief ingredients. The surfactant, nonyl phenoxypolyethoxylethanol (NP40), is an additive frequently present in pesticide formulations. We invest..
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Nephrology / Original Article
Risk factors in the progression of BK virus-associated nephropathy in renal transplant recipients
Hae Min Lee, In-Ae Jang, Dongjae Lee, Eun Jin Kang, Bum Soon Choi, Cheol Whee Park, Yeong Jin Choi, Chul Woo Yang, Yong-Soo Kim, Byung Ha Chung
Korean J Intern Med. 2015;30(6):865-872. Published online October 30, 2015
Background/Aims: BK virus-associated nephropathy (BKVAN) is an important cause of allograft dysfunction in kidney transplant recipients. It has an unfavorable clinical course, and no definite treatment guidelines have yet been established. Here, we report our center’s experience with biopsy-proven ..
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Letter to the editor
Penicillin G-induced hemorrhagic cystitis
Engin Kaya, Sercan Yilmaz
Korean J Intern Med. 2015;30(5):742-742. Published online August 27, 2015
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Ect. / Original Article
Replication of the results of genome-wide and candidate gene association studies on telomere length in a Korean population
Sook Kyung Do, Seung Soo Yoo, Yi Young Choi, Jin Eun Choi, Hyo-Sung Jeon, Won Kee Lee, Shin Yup Lee, Jaehee Lee, Seung Ick Cha, Chang Ho Kim, Jae Yong Park
Korean J Intern Med. 2015;30(5):719-726. Published online August 27, 2015
Background/Aims: A number of genome-wide and candidate gene association studies have identified polymorphisms associated with telomere length in Caucasian populations. This study was conducted to determine the impacts of 17 polymorphisms identified in Caucasians on telomere length in a Korean popula..
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Infectious diseases / Original Article
The CD4 slope can be a predictor of immunologic recovery in advanced HIV patients: a case-control study
Kye-Hyung Kim, Jongyoun Yi, Sun Hee Lee
Korean J Intern Med. 2015;30(5):705-713. Published online August 27, 2015
Background/Aims: Advanced human immunodeficiency virus (HIV) infection, despite sustained viral suppression by highly active antiretroviral therapy (HAART), is a risk factor for poor immunologic recovery. However, some patients with advanced infection do show immunologic recovery. In this study, pre..
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Infectious diseases / Original Article
Clinical significance of methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci colonization in liver transplant recipients
Youn Jeong Kim, Sang Il Kim, Jong Young Choi, Seung Kyu Yoon, Young-Kyoung You, Dong Goo Kim
Korean J Intern Med. 2015;30(5):694-704. Published online August 27, 2015
Background/Aims: Liver transplant patients are at high risk for methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE) colonization. We evaluated patients before and after liver transplant using active surveillance culture (ASC) to assess the prevalence ..
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Hemato-oncology / Original Article
Clinical characteristics and outcomes in diffuse large B cell lymphoma patients aged 70 years and older: a single-center experience with a literature review
Yun Hwa Jung, In Sook Woo, Chi Wha Han
Korean J Intern Med. 2015;30(5):684-693. Published online August 27, 2015
Background/Aims: Among diffuse large B cell lymphoma (DLBCL) patients, determining the appropriate dose and chemotherapy schedule to balance toxicity and efficacy is harder in elderly than in younger patients. Moreover, there are no currently available clinical factors that consistently identify pat..
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Gastroenterology / Original Article
Oral udenafil and aceclofenac for the prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis in high-risk patients: a randomized multicenter study
Tae Yoon Lee, Jung Sik Choi, Hyoung-Chul Oh, Tae Jun Song, Jae Hyuk Do, Young Koog Cheon
Korean J Intern Med. 2015;30(5):602-609. Published online August 27, 2015
Background/Aims: Acute pancreatitis is a common complication of endoscopic retrograde cholangiopancreatography (ERCP). Combination therapy w ith ora l udenafil and aceclofenac may reduce the occurrence of post-ERCP pancreatitis by targeting different pathophysiological mechanisms. We investigated wh..
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