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Etc. / Original Article
The Korean version of the FRAIL scale: clinical feasibility and validity of assessing the frailty status of Korean elderly
Hee-Won Jung, Hyun-Jung Yoo, Si-Young Park, Sun-Wook Kim, Jung-Yeon Choi, Sol-Ji Yoon, Cheol-Ho Kim, Kwang-il Kim
Korean J Intern Med. 2016;31(3):594-600. Published online December 23, 2015
Background/Aims: The fatigue, resistance, ambulation, illnesses, and loss of weight (FRAIL) scale is a screening tool for frailty status using a simple 5-item questionnaire. The aim of this study was to evaluate the clinical feasibility and validity of the Korean version of the FRAIL (K-FRAIL) scale..
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Hemato-oncology / Original Article
Treatment outcomes and clinical relevance of the
Follicular Lymphoma International Prognostic Index in Korean follicular lymphoma patients
treated with chemotherapy
Chi Hoon Maeng, Sung Woo Ahn, Seong-Yoon Ryu, Sungjun Han, Young Hyeh Ko, Jun Ho Ji, Won Seog Kim, Seok Jin Kim
Korean J Intern Med. 2016;31(3):560-569. Published online February 22, 2016
Background/Aims: The Follicular Lymphoma International Prognostic Index (FLIPI) and FLIPI2 are well-known prognostic models for patients with follicular lymphoma (FL). However, their prognostic relevance has not been examined before in Korean patients with FL.
Methods: We reviewed clinical and labo..
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Cardiology / Original Article
The efficacy and safety of drug-eluting balloons for the treatment of in-stent restenosis as compared with drug-eluting stents and with conventional balloon angioplasty
Pyung Chun Oh, Soon Yong Suh, Woong Chol Kang, Kyounghoon Lee, Seung Hwan Han, Taehoon Ahn, Eak Kyun Shin
Korean J Intern Med. 2016;31(3):501-506. Published online December 21, 2015
Background/Aims: Treatment of coronary in-stent restenosis (ISR) is still associated with a high incidence of recurrence. We aimed to compare the efficacy and safety of drug-eluting balloons (DEB) for the treatment of ISR as compared with conventional balloon angioplasty (BA) and drug-eluting stent..
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Gastroenterology / Original Article
Diagnostic value of alcoholic liver disease (ALD)/nonalcoholic fatty liver disease (NAFLD) index combined with γ-glutamyl transferase in differentiating ALD and NAFLD
Junling Wang, Ping Li, Zhilong Jiang, Qiuhui Yang, Yuqiang Mi, Yonggang Liu, Ruifang Shi, Yonghe Zhou, Jinsheng Wang, Wei Lu, Si Li, Dan Liu
Korean J Intern Med. 2016;31(3):479-487. Published online March 30, 2016
Background/Aims: This study aimed to verify the reliability of the alcoholic liver disease (ALD)/nonalcoholic fatty liver disease (NAFLD) index (ANI) for distinguishing ALD in patients with hepatic steatosis from NAFLD, and to investigate whether ANI combined with γ-glutamyl transferase (GGT) woul..
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Gastroenterology / Original Article
Clinical outcome of acute nonvariceal upper gastrointestinal bleeding after hours: the role of urgent endoscopy
Dong-Won Ahn, Young Soo Park, Sang Hyub Lee, Cheol Min Shin, Jin-Hyeok Hwang, Jin-Wook Kim, Sook-Hyang Jeong, Nayoung Kim, Dong Ho Lee
Korean J Intern Med. 2016;31(3):470-478. Published online April 6, 2016
Background/Aims: This study was performed to investigate the clinical role of urgent esophagogastroduodenoscopy (EGD) for acute nonvariceal upper gastrointestinal bleeding (ANVUGIB) performed by experienced endoscopists after hours.
Methods: A retrospective analysis was performed for consecutively ..
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Gastroenterology / Review
Functional dyspepsia: new insights into pathogenesis and therapy
Nicholas J. Talley
Korean J Intern Med. 2016;31(3):444-456. Published online April 6, 2016
One in 10 people suffer from functional dyspepsia (FD), a clinical syndrome comprising chronic bothersome early satiety, or postprandial fullness, or epigastric pain or burning. Postprandial distress syndrome (PDS, comprising early satiety and/or postprandial fullness) and epigastric pain syndrome (..
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Allergy / Review
What we know about nonsteroidal anti-inflammatory drug hypersensitivity
Duy Le Pham, Ji-Hye Kim, Tu Hoang Kim Trinh, Hae-Sim Park
Korean J Intern Med. 2016;31(3):417-432. Published online March 31, 2016
Nonsteroidal anti-inf lammatory drugs (NSAIDs) are widely prescribed for the treatment of inflammatory diseases, but their use is frequently related to hypersensitivity reactions. This review outlines our current knowledge of NSAID hypersensitivity (NHS) with regard to its pathogenic, molecular, and..
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Letter to the editor
Mixed-phenotype acute leukemia treated with decitabine
Ji-Young Lee, Sang-min Lee, Ja-Young Lee, Ki-Hyang Kim, Moon-Young Choi, Won-Sik Lee
Korean J Intern Med. 2016;31(2):406-408. Published online February 15, 2016
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Letter to the editor
Painful immunoglobulin G4-related thyroiditis treated by total thyroidectomy
Ihn Suk Lee, Jung Uee Lee, Kwan-Ju Lee, Yi Sun Jang, Jong Min Lee, Hye Soo Kim
Korean J Intern Med. 2016;31(2):399-402. Published online February 26, 2016
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Endocrinology-metabolism / Original Article
Comparison of two- and three-dimensional sonography for the prediction of the extrathyroidal extension of papillary thyroid carcinomas
Yang Seon Yi, Sang Soo Kim, Won Jin Kim, Min Jung Bae, Ji Hyun Kang, Bo Gwang Choi, Yun Kyung Jeon, Bo Hyun Kim, Byung Joo Lee, Soo Geun Wang, In Joo Kim, Yong Ki Kim
Korean J Intern Med. 2016;31(2):313-322. Published online December 23, 2015
Background/Aims: The purpose of this study was to compare the diagnostic validity of two-dimensional (2D) and three-dimensional (3D) ultrasonography (US) when predicting the extrathyroidal extension of papillary thyroid cancer.
Methods: All 2D data were interpreted in real time and 3D data were sto..
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Pulmonology / Original Article
Facility characteristics as independent prognostic factors of nursing home-acquired pneumonia
Che Wan Lim, Younghoon Choi, Chang Hyeok An, Sang Joon Park, Hee-Jin Hwang, Jae Ho Chung, Joo-Won Min
Korean J Intern Med. 2016;31(2):296-304. Published online February 2, 2016
Background/Aims: Recently, the incidence of nursing home-acquired pneumonia (NHAP) has been increasing and is now the leading cause of death among nursing home residents. This study was performed to identify risk factors associated with NHAP mortality, focusing on facility characteristics.
Methods:..
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Gastroenterology / Original Article
Effects of bispectral index monitoring as an adjunct to nurse-administered propofol combined sedation during colonoscopy: a randomized clinical trial
Jun Heo, Min Kyu Jung, Hyun Seok Lee, Chang Min Cho, Seong Woo Jeon, Sung Kook Kim, Young Hoon Jeon
Korean J Intern Med. 2016;31(2):260-266. Published online February 26, 2016
Background/Aims: The efficacy of bispectral index (BIS) monitoring during colonoscopic sedation is debated. We aimed to determine whether BIS monitoring was useful for propofol dose titration, and to evaluate differences in sedative administration between expert and inexperienced medical personnel d..
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Gastroenterology / Original Article
Synchronous second primary cancers in patients with squamous esophageal cancer: clinical features and survival outcome
Jin Seo Lee, Ji Yong Ahn, Kee Don Choi, Ho June Song, Yong Hee Kim, Gin Hyug Lee, Hwoon-Yong Jung, Jin-Sook Ryu, Sung-Bae Kim, Jong Hoon Kim, Seung-Il Park, Kyung-Ja Cho, Jin-Ho Kim
Korean J Intern Med. 2016;31(2):253-259. Published online February 11, 2016
Background/Aims: Unexpected diagnosis of synchronous second primary cancers (SPC) complicates physicians’ decision-making because clinical details of squamous esophageal cancer (EC) patients with SPC have been limited. We evaluated clinical features and treatment outcomes of patients with synchron..
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Gastroenterology / Review
Diagnosis and management of gastric dysplasia
Jae Kyu Sung
Korean J Intern Med. 2016;31(2):201-209. Published online February 26, 2016
Gastric dysplasia is a neoplastic lesion and a precursor of gastric cancer. The Padova, Vienna, and World Health Organization classifications were developed to overcome the discrepancies between Western and Japanese pathologic diagnoses and to provide a universally accepted classification of gastric..
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Letter to the editor
Churg-Strauss syndrome that presented with mediastinal lymphadenopathy and calculous cholecystitis
Jung Yoon Choi, Ji Eun Kim, In Young Choi, Ju Han Lee, Je Hyeong Kim, Chol Shin, Seung Heon Lee
Korean J Intern Med. 2016;31(1):179-183. Published online December 28, 2015
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Endocrinology-metabolism / Original Article
Relationship between metabolic syndrome and thyroid nodules in healthy Koreans
Juyoung Shin, Min-Hee Kim, Kun-Ho Yoon, Moo-Il Kang, Bong-Yun Cha, Dong-Jun Lim
Korean J Intern Med. 2016;31(1):98-105. Published online December 28, 2015
Background/Aims: This study evaluated the relationship between thyroid nodules and metabolic syndrome (MS) and its components in apparently healthy Koreans.
Methods: We reviewed the records of 3,298 subjects with no noticeable symptoms who underwent thyroid ultrasound imaging as part of a routine c..
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Pulmonology / Original Article
Clinical efficacy of high-flow nasal cannula compared to noninvasive ventilation in patients with post-extubation respiratory failure
Jung-Wan Yoo, Ara Synn, Jin Won Huh, Sang-Bum Hong, Younsuck Koh, Chae-Man Lim
Korean J Intern Med. 2016;31(1):82-88. Published online December 28, 2015
Background/Aims: Post-extubation respiratory failure (PERF) is associated with poor clinica l outcomes. High-f low nasa l cannula (HF NC) ox ygen therapy has been used in patients with respiratory failure, but the clinical benefit in patients with PERF remains unclear. The aim of this study was to e..
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Gastroenterology / Original Article
Predictive factors of mortality within 30 days in patients with nonvariceal upper gastrointestinal bleeding
Yoo Jin Lee, Bo Ram Min, Eun Soo Kim, Kyung Sik Park, Kwang Bum Cho, Byoung Kuk Jang, Woo Jin Chung, Jae Seok Hwang, Seong Woo Jeon
Korean J Intern Med. 2016;31(1):54-64. Published online December 28, 2015
Background/Aims: Nonvariceal upper gastrointestinal bleeding (NVUGIB) is a common medical emergency that can be life threatening. This study evaluated predictive factors of 30-day mortality in patients with this condition.
Methods: A prospective observational study was conducted at a single hospita..
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Gastroenterology / Original Article
Feasibility of α-fetoprotein as a diagnostic tool for hepatocellular carcinoma in Korea
Dae Geon Ahn, Hyung Joon Kim, Hyun Kang, Hyun Woong Lee, Si Hyun Bae, Joon Hyoek Lee, Yong Han Paik, June Sung Lee
Korean J Intern Med. 2016;31(1):46-53. Published online December 28, 2015
Background/Aims: The aim of this study was to evaluate the feasibility of α-fetoprotein (AFP) as a diagnostic tool for hepatocellular carcinoma (HCC) in Korean patients.
Methods: We retrospectively reviewed the medical records of HCC and cirrhosis patients at three hospitals. For each HCC patient..
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Gastroenterology / Original Article
New monoclonal antibody-based test for Helicobacter pylori urease in gastric tissue
Do Hyun Kim, Ho Dong Kim, Hyeuk Park, Seung Choi, Jae Won Beom, Woo Jong Kim, Chang Kook Park, Young Jik Lee, Ju Young Park, Hyung Rag Kim, Chul Park, Young Eun Joo, Young Do Jung
Korean J Intern Med. 2016;31(1):40-45. Published online December 28, 2015
Background/Aims: To evaluate a new monoclonal antibody for Helicobacter pylori urease in gastric tissue.
Methods: A total of 107 volunteers were enrolled. All subjects underwent a 13C-urea breath test and esophagogastroduodenoscopy. Gastric aspirates were analyzed for pH and ammon..
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