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Case Report
Spontaneous Cerebrospinal Fluid Rhinorrhea with Pneumocephalus: An Unusual Manifestation of Nasal Tuberculosis
Waqas Wahid Baig, Mudugundur Vishwares Nagaraja, Muralidhar Varma
Korean J Intern Med. 2012;27(3):350-352. Published online September 1, 2012
An unusual case of spontaneous cerebrospinal fluid (CSF) rhinorrhea with a pneumocephalus is described in a middle-aged woman who presented with a watery nasal discharge for 1 week and headache, vomiting, and fever for 1 day. The neurological examination revealed meningeal signs and bilateral pap..
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Case Report
A Case of Idiopathic Granulomatous Hypophysitis
Chul Ho Chung, Min Soo Song, Hyun Deuk Cho, Du Shin Jeong, Yeo Joo Kim, Hack Gun Bae, Sang Jin Kim
Korean J Intern Med. 2012;27(3):346-349. Published online September 1, 2012
Granulomatous hypophysitis is a rare pituitary condition that commonly presents with enlargement of the pituitary gland. A 31-year-old woman was admitted to the hospital with a severe headache and bitemporal hemianopsia. Magnetic resonance imaging (MRI) showed an 18 × 10-mm sellar mass with sup..
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Original Article
Interleukin-6 -634 C/G and -174 G/C Polymorphisms in Korean Patients Undergoing Hemodialysis
Jung-Hwa Ryu, Seung-Jung Kim
Korean J Intern Med. 2012;27(3):327-337. Published online September 1, 2012
Background/AimsChronic inflammatory status is a possible risk factor for vascular access dysfunction in hemodialysis (HD) patients, but susceptibility differences appear among individuals. Interleukin (IL)-6 is a well-known inflammatory cytokine with various polymorphisms. We ..
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Original Article
Validation of the Oxford Classification of IgA Nephropathy: A Single-Center Study in Korean Adults
Hoyoung Lee, Sul Hee Yi, Mi Seon Seo, Jin Nam Hyun, Jin Seok Jeon, Hyunjin Noh, Dong Cheol Han, Seung Duk Hwang, So Young Jin, Soon Hyo Kwon
Korean J Intern Med. 2012;27(3):293-300. Published online September 1, 2012
Background/AimsThe recently published Oxford classification of IgA nephropathy (IgAN) proposed a split system for histological grading, based on prognostic pathological features. This new classification system must be validated in a variety of cohorts. We investigated whether ..
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Original Article
Role of Photodynamic Therapy in the Palliation of Obstructing Esophageal Cancer
Hyeon Young Yoon, Young Koog Cheon, Hye Jin Choi, Chan Sup Shim
Korean J Intern Med. 2012;27(3):278-284. Published online September 1, 2012
Background/AimsThe aim of this non-randomized study was to determine the role of photodynamic therapy (PDT) in a multimodal approach for the palliation of advanced esophageal carcinoma. MethodsTwenty consecutive patients with obstructing esophag..
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Letter to the editor
Recurrent Thrombotic Events after Catastrophic Antiphopholipid Syndrome
Hayne Cho Park, Hyun-Bae Yoon, Tae Woo Lee, Ji Yong Jung, Ho Jun Chin, Yon Su Kim, Suhnggwon Kim
Korean J Intern Med. 2012;27(2):232-234. Published online May 31, 2012
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Original Article
Prognosis in Patients Having Chronic Obstructive Pulmonary Disease with Significant Coronary Artery Lesion Angina
Tae Yun Park, Kyung Hee Kim, Hyun Kyoung Koo, Ji Yeon Lee, Sang-Min Lee, Jae-Jun Yim, Chul-Gyu Yoo, Young Whan Kim, Sung Koo Han, Seok-Chul Yang
Korean J Intern Med. 2012;27(2):189-196. Published online May 31, 2012
Background/AimsMany studies have investigated angina and its relationship with chronic obstructive pulmonary disease (COPD). However, angina was diagnosed only by noninvasive tests or only by clinical symptoms in most of these studies. The aim of this study was to compare the ..
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Original Article
Phosphodiesterase Inhibitor Improves Renal Tubulointerstitial Hypoxia of the Diabetic Rat Kidney
Hui-Kyoung Sun, Yun Mi Lee, Kum Hyun Han, Han-Seong Kim, Seon-Ho Ahn, Sang-Youb Han
Korean J Intern Med. 2012;27(2):163-170. Published online May 31, 2012
Background/AimsRenal hypoxia is involved in the pathogenesis of diabetic nephropathy. Pentoxifyllin (PTX), a nonselective phosphodiesterase inhibitor, is used to attenuate peripheral vascular diseases. To determine whether PTX can improve renal hypoxia, we investigated its eff..
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Case Report
Spontaneous Non-Traumatic Stress Fractures in Bilateral Femoral Shafts in a Patient Treated with Bisphosphonates
Dong Yeob Shin, Cheol Ryong Ku, Kyung Min Kim, Han Seok Choi, Yumie Rhee, Eun Jig Lee, Sung-Kil Lim
Korean J Intern Med. 2012;27(1):98-102. Published online February 28, 2012
Bisphosphonates are potent inhibitors of bone resorption and widely used to treat osteoporosis. Extensive studies have shown that therapy with bisphosphonates improves bone density and decreases fracture risk. However, concerns have been raised about potential over-suppression of bone turnover du..
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Case Report
Development of Brugada Syndrome Following Photodynamic Therapy in a Patient with Cholangiocarcinoma
Duk Won Bang, Min Su Hyon, Young Duk Cho, Sung Koo Kim, Young Joo Kwon
Korean J Intern Med. 2012;27(1):95-97. Published online February 28, 2012
Brugada syndrome can be unmasked by several conditions including a febrile state, marked leukocytosis, and electrolyte disturbances. Herein, we describe a 62-year-old man with cholangiocarcinoma in the first reported case of Brugada syndrome onset following photodynamic therapy.
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Original Article
Feasibility of Non-TBI Conditioning with Busulfan and Fludarabine for Allogeneic Stem Cell Transplantation in Lymphoid Malignancy
Ho Cheol Shin, Yoo Jin Lee, Joon Ho Joon Ho, Soo Jung Lee, Byung Woog Kang, Yee Soo Chae, Jong Gwang Kim, Jun Young Choi, Jong Won Seo, Yu Kyung Kim, Jang Soo Suh, Sang Kyun Sohn
Korean J Intern Med. 2012;27(1):72-83. Published online February 28, 2012
Background/AimsThis retrospective study evaluated the transplantation outcomes of patients with adult lymphoid malignancies who received chemotherapy-based conditioning with busulfan and fludarabine (BuFlu) and busulfan and cyclophosphamide (BuCy2). Method..
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Original Article
Normalization of Negative T-Wave on Electrocardiography and Right Ventricular Dysfunction in Patients with an Acute Pulmonary Embolism
Bo-Youn Choi, Dae-Gyun Park
Korean J Intern Med. 2012;27(1):53-59. Published online February 28, 2012
Background/AimsRight ventricular dysfunction (RVD) is associated with poor prognosis in patients with acute pulmonary embolism (APE). Echocardiography and computed tomography (CT)-angiography may be difficult to perform in a serial follow up, unlike electrocardiography (ECG). ..
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Review
Optimization of Stent Deployment by Intravascular Ultrasound
Hyuck-Jun Yoon, Seung-Ho Hur
Korean J Intern Med. 2012;27(1):30-38. Published online February 28, 2012
Intravascular ultrasound (IVUS) is a useful diagnostic method that provides valuable information in addition to angiography regarding the coronary vessel lumen, dimensions, plaque burden, and characteristics. The major use of IVUS in coronary intervention is to guide interventional strategies and..
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Review
Albumin for End-Stage Liver Disease
June Sung Lee
Korean J Intern Med. 2012;27(1):13-19. Published online February 28, 2012
Albumin has been widely used in patients with cirrhosis in an attempt to improve circulatory and renal functions. The benefits of albumin infusions in preventing the deterioration in renal function associated with large-volume paracentesis, spontaneous bacterial peritonitis, and established hepat..
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Review
The Role of Optical Coherence Tomography in Coronary Intervention
Mitsuyasu Terashima, Hideaki Kaneda, Takahiko Suzuki
Korean J Intern Med. 2012;27(1):1-12. Published online February 28, 2012
Optical coherence tomography (OCT) is an optical analog of intravascular ultrasound (IVUS) that can be used to examine the coronary arteries and has 10-fold higher resolution than IVUS. Based on polarization properties, OCT can differentiate tissue characteristics (fibrous, calcified, or lipid-ri..
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Letter to the editor
Two Cases of Scrub Typhus Presenting with Guillain-Barré Syndrome with Respiratory Failure
Il Nam Ju, Jung Woo Lee, Sung Yeoun Cho, Seung Jee Ryu, Youn Jeong Kim, Sang Il Kim, Moon Won Kang
Korean J Intern Med. 2011;26(4):474-476. Published online November 28, 2011
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Case Report
A Case of Minimal Change Disease Treated Successfully with Mycophenolate Mofetil in a Patient with Systemic Lupus Erythematosus
Young Hoon Hong, Dae Young Yun, Yong Wook Jung, Myung Jin Oh, Hyun Je Kim, Choong Ki Lee
Korean J Intern Med. 2011;26(4):470-473. Published online November 28, 2011
The World Health Organization classifies lupus nephritis as class I to V or VI. However, a few cases of minimal change glomerulopathy have been reported in association with systemic lupus erythematosus (SLE). Mycophenolate mofetil has been shown to be effective for treatment of minimal change dis..
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Original Article
Clinical Implications of Elevated Antiphospholipid Antibodies in Adult Patients with Primary Immune Thrombocytopenia
Young-Joon Yang, Gak-Won Yun, Ik-Chan Song, Seung-Woo Baek, Kyu-Seop Lee, Hye Won Ryu, Myung-Won Lee, Hyo-Jin Lee, Hwan-Jung Yun, Samyong Kim, Deog-Yeon Jo
Korean J Intern Med. 2011;26(4):449-454. Published online November 28, 2011
Background/AimsAntiphospholipid antibodies (aPL) have been detected in various proportions of patients with primary immune thrombocytopenia (ITP), but the clinical significance of this is debatable. The present study aimed to determine the frequency and clinical implications o..
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Original Article
Alteration of Left Ventricular Function with Dobutamine Challenge in Patients with Myocardial Bridge
Joon-Hyung Jhi, Kyoung-Im Cho, Jong-kun Ha, Chan-Woo Jung, Bong-Jae kim, Seong-Oh Park, A-Ra Jo, Seong-Man Kim, Hyeon-Gook Lee, Tae-Ik Kim
Korean J Intern Med. 2011;26(4):410-420. Published online November 28, 2011
Background/AimsThe aim of this study was to identify changes in left ventricular (LV) performance in patients with a myocardial bridge (MB) in the left anterior descending coronary artery during resting and in an inotropic state. MethodsMyocardi..
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Original Article
A Combination of Melphalan, Prednisone, and 50 mg Thalidomide Treatment in Non-Transplant-Candidate Patients with Newly Diagnosed Multiple Myeloma
Hye Jung Chang, Jae Hoon Lee, Young Rok Do, Sung-Hwa Bae, Jung-Lim Lee, Seung Hyun Nam, Sung-Soo Yoon, Soo-Mee Bang
Korean J Intern Med. 2011;26(4):403-409. Published online November 28, 2011
Background/AimsThe clinical efficacy and safety of a three-drug combination of melphalan, prednisone, and thalidomide were assessed in patients with multiple myeloma who were not candidates for high-dose therapy as a first-line treatment. Because the side effects of thalidomid..
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