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Review
Optimization of Stent Deployment by Intravascular Ultrasound
Hyuck-Jun Yoon, Seung-Ho Hur
Korean J Intern Med. 2012;27(1):30-38. Published online February 28, 2012
Intravascular ultrasound (IVUS) is a useful diagnostic method that provides valuable information in addition to angiography regarding the coronary vessel lumen, dimensions, plaque burden, and characteristics. The major use of IVUS in coronary intervention is to guide interventional strategies and..
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Review
Albumin for End-Stage Liver Disease
June Sung Lee
Korean J Intern Med. 2012;27(1):13-19. Published online February 28, 2012
Albumin has been widely used in patients with cirrhosis in an attempt to improve circulatory and renal functions. The benefits of albumin infusions in preventing the deterioration in renal function associated with large-volume paracentesis, spontaneous bacterial peritonitis, and established hepat..
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Review
The Role of Optical Coherence Tomography in Coronary Intervention
Mitsuyasu Terashima, Hideaki Kaneda, Takahiko Suzuki
Korean J Intern Med. 2012;27(1):1-12. Published online February 28, 2012
Optical coherence tomography (OCT) is an optical analog of intravascular ultrasound (IVUS) that can be used to examine the coronary arteries and has 10-fold higher resolution than IVUS. Based on polarization properties, OCT can differentiate tissue characteristics (fibrous, calcified, or lipid-ri..
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Letter to the editor
Two Cases of Scrub Typhus Presenting with Guillain-Barré Syndrome with Respiratory Failure
Il Nam Ju, Jung Woo Lee, Sung Yeoun Cho, Seung Jee Ryu, Youn Jeong Kim, Sang Il Kim, Moon Won Kang
Korean J Intern Med. 2011;26(4):474-476. Published online November 28, 2011
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Case Report
A Case of Minimal Change Disease Treated Successfully with Mycophenolate Mofetil in a Patient with Systemic Lupus Erythematosus
Young Hoon Hong, Dae Young Yun, Yong Wook Jung, Myung Jin Oh, Hyun Je Kim, Choong Ki Lee
Korean J Intern Med. 2011;26(4):470-473. Published online November 28, 2011
The World Health Organization classifies lupus nephritis as class I to V or VI. However, a few cases of minimal change glomerulopathy have been reported in association with systemic lupus erythematosus (SLE). Mycophenolate mofetil has been shown to be effective for treatment of minimal change dis..
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Original Article
Clinical Implications of Elevated Antiphospholipid Antibodies in Adult Patients with Primary Immune Thrombocytopenia
Young-Joon Yang, Gak-Won Yun, Ik-Chan Song, Seung-Woo Baek, Kyu-Seop Lee, Hye Won Ryu, Myung-Won Lee, Hyo-Jin Lee, Hwan-Jung Yun, Samyong Kim, Deog-Yeon Jo
Korean J Intern Med. 2011;26(4):449-454. Published online November 28, 2011
Background/AimsAntiphospholipid antibodies (aPL) have been detected in various proportions of patients with primary immune thrombocytopenia (ITP), but the clinical significance of this is debatable. The present study aimed to determine the frequency and clinical implications o..
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Original Article
Alteration of Left Ventricular Function with Dobutamine Challenge in Patients with Myocardial Bridge
Joon-Hyung Jhi, Kyoung-Im Cho, Jong-kun Ha, Chan-Woo Jung, Bong-Jae kim, Seong-Oh Park, A-Ra Jo, Seong-Man Kim, Hyeon-Gook Lee, Tae-Ik Kim
Korean J Intern Med. 2011;26(4):410-420. Published online November 28, 2011
Background/AimsThe aim of this study was to identify changes in left ventricular (LV) performance in patients with a myocardial bridge (MB) in the left anterior descending coronary artery during resting and in an inotropic state. MethodsMyocardi..
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Original Article
A Combination of Melphalan, Prednisone, and 50 mg Thalidomide Treatment in Non-Transplant-Candidate Patients with Newly Diagnosed Multiple Myeloma
Hye Jung Chang, Jae Hoon Lee, Young Rok Do, Sung-Hwa Bae, Jung-Lim Lee, Seung Hyun Nam, Sung-Soo Yoon, Soo-Mee Bang
Korean J Intern Med. 2011;26(4):403-409. Published online November 28, 2011
Background/AimsThe clinical efficacy and safety of a three-drug combination of melphalan, prednisone, and thalidomide were assessed in patients with multiple myeloma who were not candidates for high-dose therapy as a first-line treatment. Because the side effects of thalidomid..
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Review
Endoscopic Therapy in Chronic Pancreatitis
Damien Meng Yew Tan, Stuart Sherman
Korean J Intern Med. 2011;26(4):384-399. Published online November 28, 2011
Chronic pancreatitis (CP) is a debilitating disease that can result in chronic abdominal pain, malnutrition, and other related complications. The main aims of treatment are to control symptoms, prevent disease progression, and correct any complications. A multidisciplinary approach involving medi..
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Review
Recent Advances in Mechanisms and Treatments of Airway Remodeling in Asthma: A Message from the Bench Side to the Clinic
Jae Youn Cho
Korean J Intern Med. 2011;26(4):367-383. Published online November 28, 2011
Airway remodeling in asthma is a result of persistent inflammation and epithelial damage in response to repetitive injury. Recent studies have identified several important mediators associated with airway remodeling in asthma, including transforming growth factor-β, interleukin (IL)-5, basic fib..
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Original Article
Acute Lymphoblastic Leukemia in Elderly Patients: A Single Institution's Experience
Dong-Yeop Shin, Inho Kim, Ki-Hwan Kim, Younak Choi, Seung Hoon Beom, Yaewon Yang, Yoojoo Lim, Eunyoung Lee, June Koo Lee, Ji Yeon Kim, Hyun Kyung Kim, Sung-Soo Yoon, Dong Soon Lee, Seonyang Park, Byoung-Kook Kim
Korean J Intern Med. 2011;26(3):328-339. Published online September 13, 2011
Background/AimsWe investigated the clinical characteristics and prognosis of elderly patients with acute lymphoblastic leukemia (ALL). MethodsWe reviewed the clinical data, laboratory findings, bone marrow findings, and cytogenetic analysis of el..
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Image of interest
A Case of Coarctation of the Aorta Diagnosed by Tardus-Parvus Renal Doppler Flow Patterns
Yun-Hwa Jung, Kwan-Wook Kim, Dae-Yoon Kim, Chul-Seung Lee
Korean J Intern Med. 2011;26(2):216-217. Published online June 1, 2011
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Case Report
False-Positive Hypermetabolic Lesions on Post-Treatment PET-CT after Influenza Vaccination
Jeong-Eun Kim, Eun Kyoung Kim, Dae Ho Lee, Sang-We Kim, Cheolwon Suh, Jung-Shin Lee
Korean J Intern Med. 2011;26(2):210-212. Published online June 1, 2011
We report a case of a 59-year-old man with testicular germ cell tumor who showed new hypermetabolic lesions at the left axillary lymph nodes on a post-treatment positron emission tomography-computed tomography (PET-CT) scan. The hypermetabolic lesions were found to be caused by an influenza vacci..
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Original Article
Role of IL-1α in Cisplatin-Induced Acute Renal Failure in Mice
Jay-Wook Lee, Woo-Jin Nam, Min-Jee Han, Jung-Ho Shin, Jin-Gun Kim, Su-Hyun Kim, Hye-Ryoun Kim, Dong-Jin Oh
Korean J Intern Med. 2011;26(2):187-194. Published online June 1, 2011
Background/AimsFor unknown reasons, caspase-1 -/- mice, protected against cisplatin-induced acute renal failure (ARF), are deficient in interleukin (IL)-1α. We thus asked whether IL-1α deficiency underlies the mechanism of protection against cisplatin-induced ARF in these mic..
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Review
Klotho and the Aging Process
Makoto Kuro-o
Korean J Intern Med. 2011;26(2):113-122. Published online June 1, 2011
The klotho gene was originally identified as a putative age-suppressing gene in mice that extends life span when overexpressed. It induces complex phenotypes resembling human premature aging syndromes when disrupted. The gene was named after a Greek goddess Klotho who spun the th..
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Case Report
Lymphocytic Interstitial Pneumonia in Primary Sjögren's Syndrome: A Case Report
Ji-Young Kim, Sung-Hoon Park, Seong-Kyu Kim, Dae-Sung Hyun, Yoon Seup Kum, Kyung-Jae Jung, Jung-Yoon Choe
Korean J Intern Med. 2011;26(1):108-111. Published online March 2, 2011
Sjögren's syndrome (SS) is an autoimmune disorder in which lymphocytes infiltrate the exocrine glands, resulting in the development of sicca symptoms. Lymphocytes may also invade various other organs and cause diverse symptoms. Interstitial pneumonia has been observed frequently in SS patients...
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Original Article
Epidemiology of Ciprofloxacin Resistance and Its Relationship to Extended-Spectrum β-Lactamase Production in Proteus mirabilis Bacteremia
Kyung Mok Sohn, Cheol-In Kang, Eun-Jeong Joo, Young Eun Ha, Doo Ryeon Chung, Kyong Ran Peck, Nam Yong Lee, Jae-Hoon Song
Korean J Intern Med. 2011;26(1):89-93. Published online March 3, 2011
Background/AimsWe evaluated the clinical features of ciprofloxacin-resistant Proteus mirabilis bacteremia and risk factors for ciprofloxacin resistance. MethodsFrom October 2000 to July 2009, 37 patients with clinically signific..
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Review
Prostaglandin D2 and TH2 Inflammation in the Pathogenesis of Bronchial Asthma
Masafumi Arima, Takeshi Fukuda
Korean J Intern Med. 2011;26(1):8-18. Published online March 2, 2011
Prostaglandin D2 (PGD2) is a major prostanoid, produced mainly by mast cells, in allergic diseases, including bronchial asthma. PGD2-induced vasodilatation and increased permeability are well-known classical effects that may be involved in allergic inflammation. R..
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Case Report
Postoperative High-Dose Intravenous Iron Sucrose with Low Dose Erythropoietin Therapy after Total Hip Replacement
Jiyeol Yoon, Sungmin Kim, Soo Chan Lee, Hongsub Lim
Korean J Intern Med. 2010;25(4):454-457. Published online November 27, 2010
Erythropoietin combined with parenteral iron sucrose therapy is an alternative to blood transfusion in anemic patients. It was shown to be effective in surgical patients in several previous studies when used in conjunction with other methods. However, there are no guidelines about safety limits i..
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Original Article
Association of the Superoxide Dismutase (V16A) and Catalase (C262T) Genetic Polymorphisms with the Clinical Outcome of Patients with Acute Paraquat Intoxication
Joong-Rock Hong, Su-Jin Seok, Du-Shin Jeong, Sang-Gon Lee, Hyo-Wook Gil, Jong-Oh Yang, Eun-Young Lee, Sae-Yong Hong
Korean J Intern Med. 2010;25(4):422-428. Published online November 27, 2010
Background/AimsMany patients with acute paraquat (PQ) intoxication die even at low PQ concentrations, whereas others with similar concentrations recover. Therefore, it is possible that individual differences in antioxidant capacity are responsible for the variable clinical out..
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