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Nephrology / Original Article
Effects of aspirin resistance and mean platelet volume on vascular access failure in hemodialysis patients
AJin Cho, Myung Jin Choi, Young-Ki Lee, Han Chae Hoon, Ja-Ryong Koo, Jong-Woo Yoon, Jung-Woo Noh
Korean J Intern Med. 2019;34(6):1304-1312. Published online July 23, 2018
Background/Aims: Maintaining the patency of vascular access (VA) in hemodialysis (HD) patients is important and can be life-saving. We investigated the effects of aspirin resistance and mean platelet volume (MPV) on VA failure in HD patients.
Methods: We enrolled 163 patients on maintenance HD. VA ..
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Nephrology / Original Article
Circulating renalase predicts all-cause mortality and renal outcomes in patients with advanced chronic kidney disease
Seon Ha Baek, Ran-hui Cha, Shin Wook Kang, Cheol Whee Park, Dae Ryong Cha, Sung Gyun Kim, Sun Ae Yoon, Sejoong Kim, Sang-Youb Han, Jung Hwan Park, Jae Hyun Chang, Chun Soo Lim, Yon Su Kim, Ki Young Na
Korean J Intern Med. 2019;34(4):858-866. Published online November 29, 2017
Background/Aims: Patients with chronic kidney disease (CKD) have been found to show markedly increased rates of end-stage renal disease, major adverse cardiovascular and cerebrovascular events (MACCEs), and mortality. Therefore, new biomarkers are required for the early detection of such clinical ou..
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Pulmonology / Original Article
Birt-Hogg-Dubé syndrome in Korean: clinicoradiologic features and long term follow-up
Joo Hee Lee, Min Joo Jeon, Joon Seon Song, Eun Jin Chae, Jin-Ho Choi, Gu-Hwan Kim, Jin Woo Song
Korean J Intern Med. 2019;34(4):830-840. Published online October 26, 2018
Background/Aims: Birt-Hogg-Dubé (BHD) syndrome is a rare autosomal dominant disorder that is characterized by skin fibrofolliculomas, pulmonary cysts, and renal tumors. The objective of this study was to describe the features of Korean patients with BHD syndrome.
Methods: Clinical data were retro..
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Nephrology / Original Article
Intradialytic exercise improves physical function and reduces intradialytic hypotension and depression in hemodialysis patients
So Yon Rhee, Jin Kyung Song, Suk Chul Hong, Jae Won Choi, Hee Jung Jeon, Dong Ho Shin, Eun Hee Ji, Eun-Hee Choi, Jiyeon Lee, Aram Kim, Seung Wook Choi, Jieun Oh
Korean J Intern Med. 2019;34(3):588-598. Published online August 25, 2017
Background/Aims: As numbers of maintenance hemodialysis patients are growing, debilitating conditions of muscle wasting and atrophy are becoming some of the greatest concerns in end-stage renal disease patients. Exercise training has various potential benefits in terms of prevention of a sustained d..
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Pulmonology / Original Article
Efficacy and predictors of response to inhaled corticosteroid treatment for chronic cough
Ji Young Hong, Joo-Hee Kim, Sunghoon Park, Yong Il Hwang, Ki-Suck Jung, Seung Hun Jang
Korean J Intern Med. 2019;34(3):559-568. Published online December 13, 2018
Background/Aims: Inhaled corticosteroids (ICS) are a treatment of choice for eosinophilic airway diseases, but their efficacy for other causes of chronic cough is controversial.
Methods: We conducted a prospective observational study to determine the ICS efficacy and clinical predictors of response t..
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Cardiology / Review
Supplementary nutrients for prevention of vascular calcification in patients with chronic kidney disease
Su Mi Lee, Won Suk An
Korean J Intern Med. 2019;34(3):459-469. Published online April 30, 2019
Vascular calcification (VC) and malnutrition associated with cardiovascular disease are common in patients with chronic kidney disease (CKD) treated with dialysis. VC, which reflects vascular aging, and malnutrition are also encountered in the non-CKD elderly population. This similarity of clinical ..
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Nephrology / Original Article
Current treatment status and medical costs for hemodialysis vascular access based on analysis of the Korean Health Insurance Database
Hyung Seok Lee, Young-Su Ju, Young Rim Song, Jwa Kyung Kim, Sun Ryoung Choi, Narae Joo, Hyung Jik Kim, Pyoungju Park, Sung Gyun Kim
Korean J Intern Med. 2018;33(6):1160-1168. Published online October 30, 2018
Background/Aims: The Republic of Korea is a country where the hemodialysis population is growing rapidly. It is believed that the numbers of treatments related to vascular access-related complications are also increasing. This study investigated the current status of treatment and medical expenses f..
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Nephrology / Original Article
Number of existing permanent teeth is associated with chronic kidney disease in the elderly Korean population
Hye-Sun Shin
Korean J Intern Med. 2018;33(6):1150-1159. Published online April 14, 2017
Background/Aims: The aim of this study was to assess the association between the number of existing permanent teeth and chronic kidney disease (CKD) in a representative sample of the elderly Korean population.
Methods: A total of 2,519 subjects who participated in the Korean National Health and Nut..
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Nephrology / Original Article
Update of aristolochic acid nephropathy in Korea
Tae Hyun Ban, Ji-Won Min, Changhwan Seo, Da Rae Kim, Yu Ho Lee, Byung Ha Chung, Kyung-Hwan Jeong, Jae Wook Lee, Beom Seok Kim, Sang-Ho Lee, Bum Soon Choi, Jin Suk Han, Chul Woo Yang
Korean J Intern Med. 2018;33(5):961-969. Published online March 20, 2018
Background/Aims: The true incidence of aristolochic acid nephropathy (AAN) is thought to be underestimated because numerous ingredients known or suspected to contain aristolochic acid (AA) are used in traditional medicine in Korea.
Methods: We collected data on cases of AAN since 1996 via a databas..
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Rheumatology / Original Article
Metabolic syndrome: prevalence and risk factors in Korean gout patients
Jae Hyun Jung, Gwan Gyu Song, Jong Dae Ji, Young Ho Lee, Jae-Hoon Kim, Young Ho Seo, Sung Jae Choi
Korean J Intern Med. 2018;33(4):815-822. Published online October 12, 2016
Background/Aims: We performed this study to investigate associations between metabolic syndrome, chronic kidney disease (CKD), and gout.
Methods: We reviewed the medical records of 151 patients with gout at the Department of Rheumatology in Korea University Ansan Hospital. The following measures we..
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Hemato-oncology / Original Article
Chronic kidney disease in the BCR-ABL1-negative myeloproliferative neoplasm: a single-center retrospective study
Seung-Woo Baek, Ji Young Moon, Hyewon Ryu, Yoon-Seok Choi, Ik-Chan Song, Hyo-Jin Lee, Hwan-Jung Yun, Samyoung Kim, Deog-Yeon Jo
Korean J Intern Med. 2018;33(4):790-797. Published online March 17, 2017
Background/Aims: Renal complications related to BCR-ABL1-negative myeloproliferative neoplasms (MPNs) have not been examined fully in Asian populations.
Methods: We analyzed estimated glomerular filtration rate (eGFR) and its changes with time retrospectively in patients with BCR-ABL1..
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Nephrology / Original Article
Notch signaling in the collecting duct regulates renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction in mice
Arum Choi, Sun Ah Nam, Wan-Young Kim, Sang Hee Park, Hyang Kim, Chul Woo Yang, Jin Kim, Yong Kyun Kim
Korean J Intern Med. 2018;33(4):774-782. Published online May 26, 2017
Background/Aims: Mind bomb-1 (Mib1) encodes an E3 ubiquitin ligase, which is required for the initiation of Notch signaling. Recently, it was demonstrated that the renal collecting duct plays an important role in renal fibrosis. Here, we investigated the role of Notch signaling in renal fibro..
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Nephrology / Review
Hepatitis C virus infection in chronic kidney disease: paradigm shift in management
So Mi Kim, Il Han Song
Korean J Intern Med. 2018;33(4):670-678. Published online June 28, 2018
Hepatitis C virus (HCV) infection in chronic kidney disease (CKD) is associated with increased liver-related morbidity and mortality rates, accelerated progression to end-stage renal disease, and risk of cardiovascular events. CKD patients with HCV infection require antiviral therapy. Pegylated inte..
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Infectious diseases / Original Article
Clinical value of procalcitonin for suspected nosocomial bloodstream infection
Joo Kyoung Cha, Ki Hwan Kwon, Seung Joo Byun, Soo Ryeong Ryoo, Jeong Hyeon Lee, Jae-Woo Chung, Hee Jin Huh, Seok Lae Chae, Seong Yeon Park
Korean J Intern Med. 2018;33(1):176-184. Published online November 8, 2017
Background/Aims: Procalcitonin (PCT) may prove to be a useful marker to exclude or predict bloodstream infection (BSI). However, the ability of PCT levels to differentiate BSI from non-BSI episodes has not been evaluated in nosocomial BSI.
Methods: We retrospectively reviewed the medical records of..
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Letter to the editor
Xp11.2 translocation renal cell carcinoma in the autosomal dominant polycystic kidney disease patient with preserved renal function
Hyuk Huh, Hyung Ah Jo, YongJin Yi, Seung Hyup Kim, Kyung Chul Moon, Curie Ahn, Hayne Cho Park
Korean J Intern Med. 2017;32(6):1108-1111. Published online October 17, 2017
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Endocrinology-metabolism / Original Article
Low serum bilirubin level predicts the development of chronic kidney disease in patients with type 2 diabetes mellitus
Kang Hee Ahn, Sang Soo Kim, Won Jin Kim, Jong Ho Kim, Yun Jeong Nam, Su Bin Park, Yun Kyung Jeon, Bo Hyun Kim, In Joo Kim, Yong Ki Kim
Korean J Intern Med. 2017;32(5):875-882. Published online May 31, 2017
Background/Aims: We evaluated whether serum bilirubin levels can predict the development of chronic kidney disease (CKD) in patients with type 2 diabetes mellitus (T2DM).
Methods: This was a retrospective observational longitudinal study of patients presenting at the Pusan National University Hospi..
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Nephrology / Review
Pre-existing arterial pathologic changes affecting arteriovenous fistula patency and cardiovascular mortality in hemodialysis patients
Ja Young Lee, Young Ok Kim
Korean J Intern Med. 2017;32(5):790-797. Published online August 22, 2017
The radiocephalic arteriovenous fistula (AVF) provides optimal vascular access for hemodialysis; it has a higher long-term patency rate and fewer complications than other vascular access methods. However, the AVF has a high primary failure rate. The presence of small-diameter vessels at anastomosis ..
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Nephrology / Original Article
The pattern of choosing dialysis modality and related mortality outcomes in Korea: a national population-based study
Hyung Jong Kim, Jung Tak Park, Seung Hyeok Han, Tae-Hyun Yoo, Hyeong-Cheon Park, Shin-Wook Kang, Kyoung Hoon Kim, Dong-Ryeol Ryu, Hyunwook Kim
Korean J Intern Med. 2017;32(4):699-710. Published online June 26, 2017
Background/Aims: Since comorbidities are major determinants of modality choice, and also interact with dialysis modality on mortality outcomes, we examined the pattern of modality choice according to comorbidities and then evaluated how such choices affected mortality in incident dialysis patients.
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Letter to the editor
Everolimus-induced activation of latent Mycobacterium tuberculosis infection in a patient with metastatic renal cell carcinoma
So-Yeon Jeon, Ho-Young Yhim, Na-Ri Lee, Eun-Kee Song, Jae-Yong Kwak, Chang-Yeol Yim
Korean J Intern Med. 2017;32(2):365-368. Published online February 2, 2016
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Letter to the editor
Ascites reinfusion dialysis of refractory ascites as a bridge to kidney and liver transplantation in a patient on hemodialysis
Kyung Yoon Chang, Hyung Wook Kim, Dong Chan Jin, Young Soo Kim
Korean J Intern Med. 2017;32(2):363-364. Published online January 19, 2016
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