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Nephrology / Original Article
Treatment of rituximab in patients with idiopathic membranous nephropathy: a case series and literature review
Soo-Jee Jeon, Ji-Hye Kim, Hee-Won Noh, Ga-Young Lee, Jeong-Hoon Lim, Hee-Yeon Jung, Jang-Hee Cho, Ji-Young Choi, Chan-Duck Kim, Yong-Lim Kim, Sun-Hee Park
Korean J Intern Med. 2022;37(4):830-840. Published online April 15, 2022
Background/Aims: Membranous nephropathy (MN) is a major cause of nephrotic syndrome in adults. This study aimed to evaluate the effect of rituximab (RTX) in patients with idiopathic MN (iMN) who have a high risk of progression.
Methods: We retrospectively analyzed data of 13 patients with iMN, who ..
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Endocrinology-metabolism / Original Article
Benefits of lumican on human bone health: clinical evidence using bone marrow aspirates
Yun Sun Lee, So Jeong Park, Jin Young Lee, Eunah Choi, Beom-Jun Kim
Korean J Intern Med. 2022;37(4):821-829. Published online April 26, 2022
Background/Aims: Lumican, a small leucine-rich proteoglycan, has shown osteoprotective effects by synchronously stimulating bone formation and suppressing bone resorption. To clarify the role of lumican in human bone metabolism, the association between lumican concentrations and osteoporosis-related..
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Pulmonology / Original Article
Prognostic outcome of treatment modalities for epidermal growth factor receptor-mutated advanced lung cancer
Seung Hun Jang, Dong Yoon Lee, Jihyeon Jeong, Won-Il Choi
Korean J Intern Med. 2022;37(4):811-820. Published online June 3, 2022
Background/Aims: The treatment of epidermal growth factor receptor (EGFR)-mutated lung cancer cases has shown remarkable development in the past two decades. However, there have been limited studies comparing the prognostic effects of EGFR-tyrosine kinase inhibitor (TKI) and other treatment modaliti..
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Pulmonology / Original Article
Microbiologic pattern and clinical outcome of non-ICU-acquired pneumonia: Korean HAP registry analysis
[corrected-article]
Jin Ho Jang, Hye Ju Yeo, Taehwa Kim, Woo Hyun Cho, Kyung Hoon Min, Sang-Bum Hong, Ae-Rin Baek, Hyun-Kyung Lee, Changhwan Kim, Youjin Chang, Hye Kyeong Park, Jee Youn Oh, Heung Bum Lee, Soohyun Bae, Jae Young Moon, Kwang Ha Yoo, Hyun-Il Gil, Kyeongman Jeon; on behalf of the Korean HAP/VAP Study Group
Korean J Intern Med. 2022;37(4):800-810. Published online June 28, 2022
Background/Aims: Most studies on hospital-acquired pneumonia (HAP) have been conducted in intensive care unit (ICU) settings. This study aimed to investigate the microbiological and clinical characteristics of non-ICU-acquired pneumonia (NIAP) and to identify the factors affecting clinical outcomes ..
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Cardiology / Original Article
Treatment delay and outcomes of ST-segment elevation myocardial infarction treated by primary percutaneous coronary intervention during the COVID-19 era in South Korea
Seok Oh, Myung Ho Jeong, Kyung Hoon Cho, Min Chul Kim, Doo Sun Sim, Young Joon Hong, Ju Han Kim, Youngkeun Ahn
Korean J Intern Med. 2022;37(4):786-799. Published online June 28, 2022
Background/Aims: Little is known about the clinical characteristics and treatment outcomes of ST-segment elevation myocardial infarction (STEMI) in Korea during the coronavirus disease 2019 (COVID-19) era. We aimed to evaluate the clinical characteristics and treatment outcomes of patients with STEM..
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Cardiology / Original Article
Predictors of recurrent acute myocardial infarction despite successful percutaneous coronary intervention
Sang Hun Lee, Myung Ho Jeong, Joon Ho Ahn, Dae Young Hyun, Kyung Hoon Cho, Min Chul Kim, Doo Sun Sim, Young Joon Hong, Ju Han Kim, Youngkeun Ahn, Jin Yong Hwang, Weon Kim, Jong Seon Park, Chang-Hwan Yoon, Seung Ho Hur, Sang Rok Lee, Kwang Soo Cha; on behalf of the KAMIR (Korea Acute Myocardial Infarction Registry)-NIH Investigators
Korean J Intern Med. 2022;37(4):777-785. Published online June 28, 2022
Background/Aims: Recurrent acute myocardial infarction (AMI) is an adverse cardiac event in patients with a first AMI. The predictors of recurrent AMI after the first AMI in patients who underwent successful percutaneous coronary intervention (PCI) have not been elucidated.
Methods: We analyzed th..
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Gastroenterology / Original Article
Clinical outcomes of metachronous recurrence of gastric epithelial neoplasia based on Helicobacter pylori infection status and microsatellite stability
Yeon-Ji Kim, Jaeyoung Kim, Woo Chul Chung
Korean J Intern Med. 2022;37(4):768-776. Published online May 4, 2022
Background/Aims: Helicobacter pylori eradication may prevent the recurrence of gastric epithelial neoplasia after endoscopic treatment. However, H. pylori eradication therapy is unlikely to prevent gastric cancer. This study determined the longterm results and clinical outcomes of pati..
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Gastroenterology / Original Article
Effect of L-carnitine on quality of life in covert hepatic encephalopathy: a randomized, double-blind, placebo-controlled study
Eileen L. Yoon, Sang Bong Ahn, Dae Won Jun, Yong Kyun Cho, Do Seon Song, Jae Yoon Jeong, Hee Yeon Kim, Young Kul Jung, Myeong Jun Song, Sung Eun Kim, Hyoung Su Kim, Soung Won Jeong, Sang Gyune Kim, Tae Hee Lee
Korean J Intern Med. 2022;37(4):757-767. Published online May 6, 2022
Background/Aims: L-carnitine is potentially beneficial in patients with hepatic encephalopathy (HE). We aimed to evaluate the impact of L-carnitine on the quality of life and liver function in patients with liver cirrhosis and covert HE.
Methods: We conducted an investigator-initiated, prospective,..
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Gastroenterology / Original Article
Improved anti-fibrotic effects by combined treatments of simvastatin and NS-398 in experimental liver fibrosis models
Seong Hee Kang, Hyung Joon Yim, Ji-won Hwang, Mi-jung Kim, Young-Sun Lee, Young Kul Jung, Hyungshin Yim, Baek-Hui Kim, Hae-Chul Park, Yeon Seok Seo, Ji Hoon Kim, Jong Eun Yeon, Soon Ho Um, Kwan Soo Byun
Korean J Intern Med. 2022;37(4):745-756. Published online June 8, 2022
Background/Aims: Efficient anti-fibrotic therapies are required for the treatment of liver cirrhosis. Hydroxymethylglutaryl-coenzyme A reductase inhibitors (statins) and cyclooxygenase-2 (COX-2) inhibitors have been reported to have anti-fibrotic effects. Here, we investigated whether combined treat..
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Review
Perioperative and anesthetic management of patients with rheumatoid arthritis
Hae-Rim Kim, Seong-Hyop Kim
Korean J Intern Med. 2022;37(4):732-739. Published online June 3, 2022
Our understanding and management of rheumatoid arthritis (RA) have greatly improved, but perioperative and anesthetic management remain challenging. RA is not limited to joints; systemic evaluation is thus required when planning perioperative management. Especially, careful airway evaluation is need..
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Review
Current state and prospects of gout treatment in Korea
Eun Hye Park, Sang Tae Choi, Jung Soo Song
Korean J Intern Med. 2022;37(4):719-731. Published online June 3, 2022
Effective management of gout includes the following: appropriate control of gout flares; lifestyle modifications; management of comorbidities; and long-term urate-lowering therapy (ULT) to prevent subsequent gout flares, structural joint damage, and shortening of life expectancy. In addition to trad..
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Guideline
Executive summary of the Korean Society of Nephrology 2021 clinical practice guideline for optimal hemodialysis treatment
Ji Yong Jung, Kyung Don Yoo, Eunjeong Kang, Hee Gyung Kang, Su Hyun Kim, Hyoungnae Kim, Hyo Jin Kim, Tae-Jin Park, Sang Heon Suh, Jong Cheol Jeong, Ji-Young Choi, Young-Hwan Hwang, Miyoung Choi, Yae Lim Kim, Kook-Hwan Oh; the Clinical Practice Guideline Work Group
Korean J Intern Med. 2022;37(4):701-718. Published online June 3, 2022
The Korean Society of Nephrology (KSN) has published a clinical practice guideline (CPG) document for maintenance hemodialysis (HD). The document, 2021 Clinical Practice Guideline on Optimal HD Treatment, is based on an extensive evidence-oriented review of the benefits of preparation, initiation, a..
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Corrigendum
Lung ultrasound for early diagnosis and severity assessment of pneumonia in patients with coronavirus disease 2019
Young-Jae Cho, Kyoung-Ho Song, Yunghee Lee, Joo Heung Yoon, Ji Young Park, Jongtak Jung, Sung Yoon Lim, Hyunju Lee, Ho Il Yoon, Kyoung Un Park, Hong Bin Kim, Eu Suk Kim
Korean J Intern Med. 2022;37(3):699 Published online April 28, 2022
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Image of interest
Periarticular calcifications in dermatomyositis
Hyemin Jeong, Chan Hong Jeon
Korean J Intern Med. 2022;37(3):697-698. Published online November 16, 2021
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Image of interest
Fibrous dysplasia in maxilla in a patient on hemodialysis with severe secondary hyperparathyroidism
Hui-Hsin Yang, Cheng-Hsien Wu, Hsin-Lin Tsai, Jei-Wen Chang
Korean J Intern Med. 2022;37(3):695-696. Published online March 29, 2022
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Image of interest
A rare case of acute transient thyroid swelling without hematoma after fine needle aspiration
Young Ki Kim, In Sun Goak, Yu Ji Kim, Heung Yong Jin, Kyung Ae Lee
Korean J Intern Med. 2022;37(3):693-694. Published online March 8, 2022
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Image of interest
Diabetic cystopathy preceding renal microabscess with papillary necrosis
Chaiho Jeong, Ye Seul Yang, Hyun-Shik Son, Tae-Seo Sohn
Korean J Intern Med. 2022;37(3):691-692. Published online April 12, 2022
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Rheumatology / Original Article
Trends in hospital visits and healthcare costs of gout and seropositive rheumatoid arthritis in Korea from 2010 to 2017 using National Healthcare Claims
Kyeong Min Son, Ju-Ryoung Kim, Hang A Park, Hyun Ah Kim
Korean J Intern Med. 2022;37(3):681-690. Published online October 26, 2021
Background/Aims: We examined temporal trends in the rate of gout and seropositive rheumatoid arthritis (RA) hospital visits and healthcare costs in Korea.
Methods: We conducted a serial cross-sectional analysis of Korean national healthcare claims. We calculated the annual increase in hospital visi..
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