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Original Article
Diagnosis and Species Identification of Mycobacterial Infections by Polymerase Chain Reaction-Restriction Fragment Length Polymorphism Analysis of Sterile Body Fluids
Cheong Ho Cho, Sang Hoon Han, Bum Sik Chin, Suk Hoon Choi, Han Sung Lee, Chang Oh Kim, Myung Soo Kim, Jun Yong Choi, Young Goo Song, June Myung Kim
Korean J Intern Med. 2009;24(2):135-138. Published online June 8, 2009
Background/AimsThe development of effective, accurate, and rapid diagnostic methods for Mycobacterium infection and mycobacterial species identification is required. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) is an easy, rapi..
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Original Article
Clinicopathologic Characteristics of T-cell Non-Hodgkin's Lymphoma: A Single Institution Experience
Ock Bae Ko, Dae Ho Lee, Sang We Kim, Jung Shin Lee, Shin Kim, Jooryung Huh, Cheolwon Suh
Korean J Intern Med. 2009;24(2):128-134. Published online June 8, 2009
Background/AimsAlthough the incidence of T-cell non-Hodgkin's lymphoma (NHL) is higher in Far East Asia than in Western countries, its incidence and clinical course in Korea are not well-defined. Therefore, we assessed the relative frequency and clinical features of T-cell NHL..
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Original Article
Diagnostic Yield of Tissue Sampling Using a Bite-On-Bite Technique for Incidental Subepithelial Lesions
Jeong-Seon Ji, Bo-In Lee, Kyu-Yong Choi, Byung-Wook Kim, Hwang Choi, Min Huh, Woo-Chul Chung, Hiun-Suk Chae, In-Sik Chung
Korean J Intern Med. 2009;24(2):101-105. Published online June 8, 2009
Background/AimsTechniques for endoscopic evaluation of gastrointestinal subepithelial lesions include conventional endoscopy, jumbo biopsy, endoscopic ultrasonogrphy (EUS), EUS-guided fine needle aspiration, and endoscopic submucosal resection. However, these procedures have m..
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Original Article
Marked Recovery From Paraquat-Induced Lung Injury During Long-Term Follow-up
Kwon-Hyun Lee, Hyo-Wook GIL, Young-Tong Kim, Jong-Oh Yang, Eun-Young Lee, Sae-Yong Hong
Korean J Intern Med. 2009;24(2):95-100. Published online June 8, 2009
Background/AimsParaquat-induced lung injury has been considered a progressive and irreversible disease. The purpose of this study was to report the long-term evolution of lung lesions in eight survivors with significant paraquat-induced lung injuries who could be followed-up f..
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Review
Established and Newly Proposed Mechanisms of Chronic Cyclosporine Nephropathy
Hye Eun Yoon, Chul Woo Yang
Korean J Intern Med. 2009;24(2):81-92. Published online June 8, 2009
Cyclosporine (CsA) has improved patient and graft survival rates following solid-organ transplantation and has shown significant clinical benefits in the management of autoimmune diseases. However, the clinical use of CsA is often limited by acute or chronic nephropathy, which remains a major pro..
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Case Report
An Antinuclear Antibody-Negative Patient With Lupus Nephritis
Hyoun-Ah Kim, Jae-Wook Chung, Han-Jung Park, Dai-Yeol Joe, Hyun-Ee Yim, Hae-Sim Park, Chang-Hee Suh
Korean J Intern Med. 2009;24(1):76-79. Published online March 6, 2009
Systemic lupus erythematosus (SLE) is a typical autoimmune disease that's characterized by various autoantibodies to nuclear and cytoplasmic antigens. The presence of antinuclear antibodies (ANA) in serum is generally considered a decisive diagnostic sign of SLE. However, a small subset of SLE pa..
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Original Article
A Comparison of Patient Acceptance and Preferences Between CT Colonography and Conventional Colonoscopy in Colorectal Cancer Screening
Hyuk Sang Jung, Dong Kyun Park, Min Ju Kim, Sang Kyun Yu, Kwang An Kwon, Yang Suh Ku, Yu Kyung Kim, Ju Hyun Kim
Korean J Intern Med. 2009;24(1):43-47. Published online March 6, 2009
Background/AimsColorectal cancer, one of the most common cancers in developed countries, is curable when diagnosed at an early stage. However, for better screening, both a test that patients will tolerate and diagnostic accuracy are required. We compared patient experiences an..
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Original Article
Gemcitabine, Etoposide, Cisplatin, and Dexamethasone in Patients With Refractory or Relapsed Non-Hodgkin's Lymphoma
Ki-Hyang Kim, Young-Don Joo, Chang-Hak Sohn, Ho-Jin Shin, Joo-Seop Chung, Goon-Jae Cho, Sung-Hoon Shin, Yang-Soo Kim, Won-Sik Lee
Korean J Intern Med. 2009;24(1):37-42. Published online March 6, 2009
Background/AimsTo date, an effective salvage chemotherapy regimen for the treatment of refractory or relapsing non-Hodgkin's lymphoma (NHL) has not been discovered. This study was conducted to evaluate the efficacy and safety of gemcitabine, etoposide, cisplatin, and dexametha..
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Original Article
Relationship Between Left Atrial Size and Stroke in Patients With Sinus Rhythm and Preserved Systolic Function
Bong Soo Kim, Hyun Jik Lee, Jae Hoon Kim, Hee Sang Jang, Byung Seok Bae, Hyun Jae Kang, Bong Ryeol Lee, Byung Chun Jung
Korean J Intern Med. 2009;24(1):24-32. Published online March 6, 2009
Background/AimsIncreased left atrial (LA) size has been proposed as a predictor of poor cardiovascular outcome in the elderly. In the present study, we evaluated the relationship between LA size and stroke in subjects of all ages who presented with preserved left ventricular s..
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Review
Overview of Therapeutic Drug Monitoring
Ju-Seop Kang, Min-Ho Lee
Korean J Intern Med. 2009;24(1):1-10. Published online March 6, 2009
Therapeutic drug monitoring (TDM) is the clinical practice of measuring specific drugs at designated intervals to maintain a constant concentration in a patient's bloodstream, thereby optimizing individual dosage regimens. It is unnecessary to employ TDM for the majority of medications, and it is..
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Original Article
Autologous stem cell transplantation for diffuse large B-cell lymphoma with residual extranodal involvement
Ock Bae Ko, Geundoo Jang, Shin Kim, Jooryung Huh, Cheolwon Suh
Korean J Intern Med. 2008;23(4):182-190. Published online December 29, 2008
Background/AimsDiffuse large B-cell lymphoma (DLBCL) in Koreans is frequently accompanied by extranodal (EN) disease at the time of autologous stem cell transplantation (ASCT). We sought to determine whether high EN involvement affected survival following ASCT in Koreans. <..
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Original Article
Comparison of the 13C-urea breath test and the endoscopic phenol red mucosal pH test in the quantification of Helicobacter pylori infection loading
Young-Seok Cho, Hiun-Suk Chae, Se Na Jang, Jin-Soo Kim, Hye Suk Son, Hyung-Keun Kim, Byung-Wook Kim, Sok-Won Han, Kyu-Yong Choi, Hae Kyung Lee, Eun Deok Chang
Korean J Intern Med. 2008;23(3):134-139. Published online September 20, 2008
Background/AimsThe 13C-urea breath test (UBT) is a semiquantitative test for measuring Helicobacter pylori infection loading. H. pylori produces ammonia, which elevates the pH of the gastric mucosa and is detectable via endoscopy us..
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Original Article
Endoscopic findings around the gastroesophageal junction: an experience from a tertiary hospital in Korea
Ji Hyun Kim, Jin Ki Hwang, Juhyung Kim, Sehe Dong Lee, Beom Jae Lee, Jae Seon Kim, Young-Tae Bak
Korean J Intern Med. 2008;23(3):127-133. Published online September 20, 2008
Background/AimsImportant lesions related to gastroesophageal reflux disease (GERD) are located around the gastroesophageal junction (GEJ). This study examined the distribution of endoscopic findings around the GEJ and elucidated their relationship to each other and esophageal ..
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Original Article
N-terminal pro-B-type natriuretic peptide as a marker of disease severity in patients with pericardial effusions
Shin-Jae Kim, Eun-Seok Shin, Sang-Gon Lee
Korean J Intern Med. 2008;23(2):78-86. Published online June 20, 2008
Backgraound/AimsN-terminal pro-B-type natriuretic peptide (NT-proBNP) has recently been introduced as a useful marker in diagnosing underlying disease in patients with dyspnea and for determining the prognosis of patients with heart failure. The purpose of this study was to ev..
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Original Article
The investigation of macrophage infiltration in the early phase of ischemic acute renal failure in mice
Soo-Jeong Yu, Dong-Jin Oh, Suk-Hee Yu
Korean J Intern Med. 2008;23(2):64-71. Published online June 20, 2008
Background/AimsInflammation plays a key role in ischemic acute renal failure (ARF). The present study investigated the infiltration of macrophages in the early phase of ischemic ARF in mice. MethodsIschemic ARF was induced by ..
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Original Article
Epstein-Barr Virus-Positivity in Tumor has no Correlation with the Clinical Outcomes of Patients with Angioimmunoblastic T-cell Lymphoma
Yuna Lee, Keun-Wook Lee, Jee-Hyun Kim, Soo-Mee Bang, Jong Seok Lee, Byeong-Bae Park, Won Seok Kim, Cheolwon Suh, Jung Hun Kang, Baek Yeol Ryoo, Jae Hoon Lee, Dong Bok Shin
Korean J Intern Med. 2008;23(1):30-36. Published online March 20, 2008
Background/AimsEpstein-Barr virus (EBV) is involved in the pathogenesis of angioimmunoblastic T-cell lymphoma (AILT), but its precise role and prognostic impact are not clear. This study aimed to evaluate the incidence of EBV-postitivity in the tumor and bone ..
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Original Article
Detection of Celiac Ganglia with Radial Scanning Endoscopic Ultrasonography
Tae-In Ha, Gwang-Ha Kim, Dae-Hwan Kang, Geun-Am Song, Suk Kim, Jun-Woo Lee
Korean J Intern Med. 2008;23(1):5-8. Published online March 20, 2008
Background/AimsIt has been recently reported that celiac ganglia can be identified by linear-array endoscopic ultrasonography (EUS). Still, there has been no report on the detection rate of celiac ganglia with radial scanning EUS. The aim of this study was to evaluate the dete..
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Original Article
Clinical Observation of 12 Farmers Who Believe Themselves to Have Suffered from Chronic Pesticide Intoxication
Zoong-Rock Hong, So-Young Hong, Mi-Jung Han, Hae-seung Lee, Hyo-Ook Gil, Jong-O Yang, En-Yung Lee, Sae-Yong Hong
Korean J Intern Med. 2008;23(1):1-4. Published online March 20, 2008
Background/AimsWe assessed twelve cases of suspected chronic pesticide intoxication, with medically unexplained physical symptoms. MethodsComplete blood cell count (CBC), blood chemistry, routine urinalysis, chest X-ray, ECG, ..
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Case Report
Duodenal Mucosa-Associated Lymphoid Tissue Lymphoma: A Case Report
Kyung Hee Woo, Jung Han Kim, Seong Bo Yoon, Joo Hyun Jang, Dong Hun Lee, Seong Ho Hong, Il Hyun Baek
Korean J Intern Med. 2007;22(4):296-299. Published online December 20, 2007
Primary duodenal mucosa associated lymphoid tissue (MALT) lymphoma is very rare, and little is known about its clinical course or effective treatment. We describe a case of primary duodenal MALT lymphoma that was resistant to Helicobacter pylori (H. pylori) eradi..
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Original Article
Effects of TNF-α and Leptin on Weight Loss in Patients with Stable Chronic Obstructive Pulmonary Disease
Kyeong-Cheol Shin, Jin Hong Chung, Kwan Ho Lee
Korean J Intern Med. 2007;22(4):249-255. Published online December 20, 2007
BackgroundWeight loss is common in patients with chronic obstructive pulmonary disease (COPD). However, the mechanisms of this weight loss are still unclear. MethodsSixty male patients with stable COPD and 45 healthy male cont..
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