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Case Report
Primary Adenosquamous Cell Carcinoma of the Pancreas: A Case Report with a Review of the Korean Literature
Youn Ju Na, Ki-Nam Shim, Min Sun Cho, Sun Hee Sung, Sung-Ae Jung, Kwon Yoo, Kyu Won Chung
Korean J Intern Med. 2011;26(3):348-351. Published online September 13, 2011
The most common pancreatic cancer is adenocarcinoma. Primary adenosquamous cell carcinoma of the pancreas is very rare and aggressive. A 46-year-old man presented with a 3-month history of dyspepsia and a 7-kg weight loss. The physical examination showed tenderness of the right upper quadrant of..
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Original Article
Acute Lymphoblastic Leukemia in Elderly Patients: A Single Institution's Experience
Dong-Yeop Shin, Inho Kim, Ki-Hwan Kim, Younak Choi, Seung Hoon Beom, Yaewon Yang, Yoojoo Lim, Eunyoung Lee, June Koo Lee, Ji Yeon Kim, Hyun Kyung Kim, Sung-Soo Yoon, Dong Soon Lee, Seonyang Park, Byoung-Kook Kim
Korean J Intern Med. 2011;26(3):328-339. Published online September 13, 2011
Background/AimsWe investigated the clinical characteristics and prognosis of elderly patients with acute lymphoblastic leukemia (ALL). MethodsWe reviewed the clinical data, laboratory findings, bone marrow findings, and cytogenetic analysis of el..
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Original Article
Insulin Resistance as a Risk Factor for Gallbladder Stone Formation in Korean Postmenopausal Women
Sang Soo Kim, Jeong Gyu Lee, Dong Wok Kim, Bo Hyun Kim, Yun Kyung Jeon, Mi Ra Kim, Jeong Eun Huh, Ji Young Mok, Seong-Jang Kim, Yong Ki Kim, In Joo Kim
Korean J Intern Med. 2011;26(3):285-293. Published online September 13, 2011
Background/AimsThe objective of this study was to determine whether insulin resistance is associated with gallbladder stone formation in Korean women based on menopausal status. MethodsThe study included 4,125 consecutive Korean subjects (30-79 ..
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Review
Molecular Epidemiology of Hepatitis B Virus
Jia-Horng Kao
Korean J Intern Med. 2011;26(3):255-261. Published online September 13, 2011
Although safe and effective vaccines for hepatitis B virus (HBV) have been available for nearly three decades, this virus kills at least 600,000 people annually worldwide and remains the leading global cause of chronic hepatitis, cirrhosis, and hepatocellular carcinoma. Because the HBV reverse tr..
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Image of interest
Ectopic Thyroid Nodule in Thyroglossal Duct
Ah-Young Shin, Seung-Hwan Lee, Won Sang Jung, Seung-Hyun Ko, Yu-Bae Ahn
Korean J Intern Med. 2011;26(2):218-219. Published online June 1, 2011
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Image of interest
A Case of Coarctation of the Aorta Diagnosed by Tardus-Parvus Renal Doppler Flow Patterns
Yun-Hwa Jung, Kwan-Wook Kim, Dae-Yoon Kim, Chul-Seung Lee
Korean J Intern Med. 2011;26(2):216-217. Published online June 1, 2011
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Case Report
Primary Small Cell Carcinoma of the Lung Presenting with Breast and Skin Metastases
Fatih Altintoprak, Halil Fırat Baytekin, Canatan Tasdemir
Korean J Intern Med. 2011;26(2):207-209. Published online June 1, 2011
Cutaneous metastases originating from an internal cancer are relatively uncommon in clinical practice, and metastatic lesions to the breast are rarer than those to the skin. Skin metastases of lung cancer, which may be the first sign of the disease, usually indicate progressive disease and a poor..
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Case Report
Application of Helical Tomotherapy for Two Cases of Advanced Hepatocellular Carcinoma
Joon Sung Kim, Chan Ran You, Jeong Won Jang, Si-Hyun Bae, Jong Yong Choi, Seung Kew Yoon, Chul Seung Kay
Korean J Intern Med. 2011;26(2):201-206. Published online June 1, 2011
The role of radiotherapy in the treatment of hepatocellular carcinoma (HCC) has been limited to date, because the liver has a low tolerance to radiation. However, reconstructing tumors and surrounding organs via a three-dimensional conformal planning system can avoid excess radiotherapy exposure ..
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Original Article
Diagnostic Value of a Chimeric TSH Receptor (Mc4)-Based Bioassay for Graves' Disease
Ji In Lee, Hye Won Jang, Soo Kyoung Kim, Joon Young Choi, Ji Young Kim, Kyu Yeon Hur, Jae Hyeon Kim, Yong-Ki Min, Jae Hoon Chung, Sun Wook Kim
Korean J Intern Med. 2011;26(2):179-186. Published online June 1, 2011
Background/AimsGraves' disease (GD) is caused by thyroid-stimulating hormone receptor (TSHR) and thyroid-stimulating immunoglobulin (TSI). We used a recently introduced, technically enhanced TSI bioassay to assess its diagnostic value and determine the cut-off in patients in h..
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Original Article
Effects of D-003 (10 mg/day) on Bone Mineral Density of the Lumbar Spine and Femoral Neck in Postmenopausal Women: A Randomized, Double-Blinded Study
Alfredo Ceballos, Gladys Castaño, Sarahí Mendoza, Juan González, Rosa Mas, Lilia Fernández, José Illnait, Meilis Mesa, Rafael Gámez, Julio César Fernández, Ricardo Telles, Duany Marrero, Mainel Gómez Eng, Dalmer Ruiz, Yunaisi Jardines
Korean J Intern Med. 2011;26(2):168-178. Published online June 1, 2011
Background/AimsIncreased osteoclast activity is a pivotal finding in osteoporosis. This increase is mediated via the mevalonate-to-cholesterol pathway, which is involved in producing the intermediates required for osteoclast activity. D-003, a mixture of high molecular weight ..
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Original Article
Retrospective Comparison of Levofloxacin and Moxifloxacin on Multidrug-Resistant Tuberculosis Treatment Outcomes
Jinwoo Lee, Chang-Hoon Lee, Deog Kyeom Kim, Ho Il Yoon, Jae Yeol Kim, Sang-Min Lee, Seok-Chul Yang, Jae Ho Lee, Chul-Gyu Yoo, Choon-Taek Lee, Hee Soon Chung, Young Whan Kim, Sung Koo Han, Jae-Joon Yim
Korean J Intern Med. 2011;26(2):153-159. Published online June 1, 2011
Background/AimsTo compare the effect of levofloxacin and moxifloxacin on treatment outcomes among patients with multidrug-resistant tuberculosis (MDR-TB). MethodsA retrospective analysis of 171 patients with MDR-TB receiving either levofloxacin ..
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Original Article
Endoscopic Cryotherapy of Lung and Bronchial Tumors: A Systematic Review
Seon-Heui Lee, Won-Jung Choi, Sook-Whan Sung, Young-Kyoon Kim, Chi-Hong Kim, Jae-Il Zo, Kwang-Joo Park
Korean J Intern Med. 2011;26(2):137-144. Published online June 1, 2011
Background/AimsWe made a systematic review and evaluation of endoscopic cryotherapy of endobronchial tumors, investigating safety and efficacy. MethodsQualified studies regarding endoscopic cryotherapy of lung tumors were systemically evaluated ..
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Case Report
Duodenal Somatostatinoma: A Case Report and Review
Jung A Kim, Won-Ho Choi, Chul Nam Kim, Young Soo Moon, Sun Hee Chang, Hye Ran Lee
Korean J Intern Med. 2011;26(1):103-107. Published online March 2, 2011
Somatostatinomas are rare functioning carcinoid tumors that usually arise in the pancreas and duodenum. They are seldom associated with typical clinical symptoms; their diagnosis is confirmed only by histological and immunohistochemical studies and the presence of specific hormones. Two distinct ..
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Case Report
Successful Treatment of Stereotactic Body Radiation Therapy Combined with Transarterial Chemolipiodolization for Hepatocellular Carcinoma with Biliary Obstruction
Chan-Kwon Park, Si-Hyun Bae, Hong-Jun Yang, Ho-Jong Chun, Il-Bong Choi, Jong-Young Choi, Seung-Kew Yoon
Korean J Intern Med. 2011;26(1):94-98. Published online March 2, 2011
Conventional radiation therapy (RT) is a widely recognized treatment for hepatocellular carcinoma (HCC). However, conventional RT plays only a limited role in HCC treatment because of its low efficacy and the low tolerance of the liver for this modality. Stereotactic body radiation therapy (SBRT)..
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Original Article
Effects of the Transition from Premenopause to Postmenopause on Lipids and Lipoproteins: Quantification and Related Parameters
Eun Jeung Cho, Yun Joo Min, Min Seok Oh, Jee Eun Kwon, Jeung Eun Kim, Wang-Soo Lee, Kwang Je Lee, Sang-Wook Kim, Tae Ho Kim, Myung-A Kim, Chee Jeong Kim, Wang Seong Ryu
Korean J Intern Med. 2011;26(1):47-53. Published online March 2, 2011
Background/AimsThe aim of this study was to quantitatively measure changes in lipids and lipoproteins during perimenopause and to identify variables related to these changes. MethodsAmong women who had three regular health evaluations over a spa..
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Original Article
Prognostic Factors Associated with Survival in Patients with Primary Duodenal Adenocarcinoma
Woo Chul Chung, Chang Nyol Paik, Sung Hoon Jung, Kang-Moon Lee, Sang Woo Kim, U-Im Chang, Jin Mo Yang
Korean J Intern Med. 2011;26(1):34-40. Published online March 2, 2011
Background/AimsThe prognostic factors in primary duodenal adenocarcinoma remain controversial. This study evaluated the prognostic factors associated with survival in patients with primary duodenal adenocarcinoma. MethodsFrom March 1996 to June ..
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Review
Prostaglandin D2 and TH2 Inflammation in the Pathogenesis of Bronchial Asthma
Masafumi Arima, Takeshi Fukuda
Korean J Intern Med. 2011;26(1):8-18. Published online March 2, 2011
Prostaglandin D2 (PGD2) is a major prostanoid, produced mainly by mast cells, in allergic diseases, including bronchial asthma. PGD2-induced vasodilatation and increased permeability are well-known classical effects that may be involved in allergic inflammation. R..
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Case Report
Anaplastic Thyroid Carcinoma Initially Presented with Abdominal Cutaneous Mass and Hyperthyroidism
Kyu-Hyoung Lim, Keun-Wook Lee, Jee Hyun Kim, So Yeon Park, Sung-Hee Choi, Jong Seok Lee
Korean J Intern Med. 2010;25(4):450-453. Published online November 27, 2010
A 63-year-old female was admitted to our hospital with a tender abdominal wall mass about 15 cm in diameter, which she had for 1 month. About 1 week earlier, the patient had also perceived a mass in the neck area. Computed tomography revealed huge thyroid and periumbilical masses. The thyroid hor..
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Original Article
Engagement of Toll-Like Receptor 3 Induces Vascular Endothelial Growth Factor and Interleukin-8 in Human Rheumatoid Synovial Fibroblasts
Su-Jin Moon, Mi-Kyung Park, Hye-Jwa Oh, Seon-Yeong Lee, Seung-Ki Kwok, Mi-La Cho, Ji Hyeon Ju, Kyung-Su Park, Ho-Youn Kim, Sung-Hwan Park
Korean J Intern Med. 2010;25(4):429-435. Published online November 27, 2010
Background/AimsAngiogenesis, which is a critical step in the initiation and progression of rheumatoid arthritis (RA), involves pro-angiogenic factors, including interleukin (IL)-8 and vascular endothelial growth factor (VEGF). We investigated the role of Toll-like receptor 3 (..
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Original Article
Role of 68Ga-DOTATOC PET/CT in the Evaluation of Primary Pulmonary Carcinoids
Tarun Jindal, Arvind Kumar, Balasubramanian Venkitaraman, Roman Dutta, Rakesh Kumar
Korean J Intern Med. 2010;25(4):386-391. Published online November 27, 2010
Background/AimsAlthough carcinoid tumors usually have good prognosis, early and specific diagnosis is important. Computed tomography and magnetic resonance imaging do not provide findings that are specific for carcinoids, and somatostatin receptor scintigraphy suffers from low..
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