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Case Report
A New Onset of Systemic Lupus Erythematosus Developed After Bee Venom Therapy
Young Hee Rho, Jin-Hyun Woo, Seong Jae Choi, Young Ho Lee, Jong Dae Ji, Gwan Gyu Song
Korean J Intern Med. 2009;24(3):283-285. Published online August 26, 2009
Lupus is a systemic autoimmune disease of an unknown origin, and systemic lupus erythematosus (SLE) can be triggered by numerous stimuli. Bee venom therapy is an alternative therapy that is believed to be effective for various kinds of arthritis. We present here a case of a 49-year-old female who..
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Original Article
Bone Marrow T Cells are Superior to Splenic T Cells to Induce Chimeric Conversion After Non-Myeloablative Bone Marrow Transplantation
Hyun-Sil Park, Seok-Goo Cho, Min-Jung Park, So-Youn Min, Hong-Seok Chang, Hee-Je Kim, Seok Lee, Chang-Ki Min, Jong-Wook Lee, Woo-Sung Min, Chun-Choo Kim, Ho-Youn Kim
Korean J Intern Med. 2009;24(3):252-262. Published online August 26, 2009
Background/AimsThe bone marrow functions not only as the primary B-lymphocyte-producing organ but also as a secondary lymphoid organ for CD4 and CD8 cell responses and a site of preferential homing and persistence for memory T cells. Bone marrow T (BM-T) cells are distinguishe..
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Original Article
Endoscopic and Histopathologic Predictors of Recurrence of Colorectal Adenoma on Lowering the Miss Rate
Jeong-Seon Ji, Kyu-Yong Choi, Won-Chul Lee, Bo-In Lee, Soo-Heon Park, Hwang Choi, Byung-Wook Kim, Hiun-Suk Chae, Yong-Moon Park, Young-Jun Park
Korean J Intern Med. 2009;24(3):196-202. Published online August 26, 2009
Background/AimsAlthough colorectal adenoma is reported to recur frequently, this may result from missing it at baseline. However, few studies of recurrence have considered the miss rate. This study evaluated the recurrence rate prospectively and clinical predictors of recurren..
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Original Article
Early Detection Of Asymptomatic Coronary Artery Disease In Patients With Type 2 Diabetes Mellitus
Won Sang Yoo, Hee Jin Kim, Dohee Kim, Myung Yong Lee, Hyun-Kyung Chung
Korean J Intern Med. 2009;24(3):183-189. Published online August 26, 2009
Background/AimsIn type 2 diabetic patients, coronary artery disease (CAD) is usually detected at an advanced stage due to a lack of symptoms. The aim of this study was to define which clinical parameters or non-invasive tests predict CAD in asymptomatic type 2 diabetic patients..
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Case Report
Acute Fibrinous and Organizing Pneumonia Following Hematopoietic Stem Cell Transplantation
Sang Min Lee, Jae-Jung Park, Sun Hee Sung, Yookyung Kim, Kyoung Eun Lee, Yeung-Chul Mun, Soon Nam Lee, Chu Myong Seong
Korean J Intern Med. 2009;24(2):156-159. Published online June 8, 2009
A 60-year-old man presented with cough, sputum, and dyspnea. He had a history of acute myeloid leukemia and hematopoietic stem cell transplantation with chronic renal failure. Chest CT scans showed miliary nodules and patchy consolidations. Histological examination revealed numerous fibrin balls ..
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Case Report
A Case of Hepatocellular Carcinoma Within Hepatocellular Adenoma in a Non-Cirrhotic Male
Dong Hwan Kim, Seung Up Kim, Dong Hyuk Nam, Yoon Jung Choi, Soo Mi Park, Chon Kyun Lee, Do Young Kim
Korean J Intern Med. 2009;24(2):147-152. Published online June 8, 2009
Hepatocellular adenoma (HA) is a benign hepatic lesion that predominantly occurs in young women. Most hepatocellular carcinomas (HCC) arise in a cirrhotic liver during the fifth or sixth decades. There have been several reported cases of HCC developing from HA in female patients. However, there a..
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Original Article
The Pulmonary Embolism Severity Index in Predicting the Prognosis of Patients With Pulmonary Embolism
Won-Ho Choi, Sung Uk Kwon, Yoon Jung Jwa, Jung A Kim, Yun-Ho Choi, Je Ho Chang, Hoon Jung, Joon Hyung Doh, June Namgung, Sung Yun Lee, Won Ro Lee
Korean J Intern Med. 2009;24(2):123-127. Published online June 8, 2009
Background/AimsMany prognostic models have been developed to help physicians make medical decisions on treating patients with pulmonary embolism. Among these models, the Pulmonary Embolism Severity Index (PESI) has been shown to be a successful risk stratification tool for pat..
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Original Article
Diagnostic Yield of Tissue Sampling Using a Bite-On-Bite Technique for Incidental Subepithelial Lesions
Jeong-Seon Ji, Bo-In Lee, Kyu-Yong Choi, Byung-Wook Kim, Hwang Choi, Min Huh, Woo-Chul Chung, Hiun-Suk Chae, In-Sik Chung
Korean J Intern Med. 2009;24(2):101-105. Published online June 8, 2009
Background/AimsTechniques for endoscopic evaluation of gastrointestinal subepithelial lesions include conventional endoscopy, jumbo biopsy, endoscopic ultrasonogrphy (EUS), EUS-guided fine needle aspiration, and endoscopic submucosal resection. However, these procedures have m..
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Case Report
Successful Treatment of Small-Cell Lung Cancer With Irinotecan in a Hemodialysis Patient With End-Stage Renal Disease
Dong Min Kim, Hyun Lee Kim, Choon Hae Chung, Chi Young Park
Korean J Intern Med. 2009;24(1):73-75. Published online March 6, 2009
The prognosis of patients with end-stage renal disease has improved with advances in hemodialysis techniques. However, many patients who undergo hemodialysis suffer from various types of cancer. Limited data is available to guide clinical management of these patients who may have impaired renal f..
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Case Report
Long-Term Survival in a Patient With Ruptured Hepatocellular Carcinoma
Joon Sung Kim, Seung Kew Yoon, Jeong Ah Kim, Chang Wook Kim, Si Hyun Bae, Jong Young Choi, Chan-Kwon Jung
Korean J Intern Med. 2009;24(1):63-67. Published online March 6, 2009
A 57-yr-old woman previously diagnosed with chronic hepatitis B was admitted via the emergency room because she suddenly developed epigastric pain with abdominal distension. On computed tomography (CT), a round enhancing mass was found on the left hepatic lobe with ascites in the peritoneal space..
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Original Article
The Effect of Residual Renal Function at the Initiation of Dialysis on Patient Survival
Seoung Gu Kim, Nam Ho Kim
Korean J Intern Med. 2009;24(1):55-62. Published online March 6, 2009
Background/AimsThe optimal time point for initiating renal replacement therapy in patients with end-stage renal disease remains controversial. The primary objective of our study was to determine the effects of residual renal function at the beginning of renal replacement thera..
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Original Article
EGFR and KRAS Mutations in Patients With Adenocarcinoma of the Lung
Tae Won Jang, Chul Ho Oak, Hee Kyung Chang, Soon Jung Suo, Mann Hong Jung
Korean J Intern Med. 2009;24(1):48-54. Published online March 6, 2009
Background/AimsMutations of the epidermal growth factor receptor (EGFR) and Kirsten rat sarcoma viral oncogene (KRAS) are important in the pathogenesis of lung cancer, and recent reports have revealed racial and geographical differences in mutation expression.
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Original Article
A Comparison of Patient Acceptance and Preferences Between CT Colonography and Conventional Colonoscopy in Colorectal Cancer Screening
Hyuk Sang Jung, Dong Kyun Park, Min Ju Kim, Sang Kyun Yu, Kwang An Kwon, Yang Suh Ku, Yu Kyung Kim, Ju Hyun Kim
Korean J Intern Med. 2009;24(1):43-47. Published online March 6, 2009
Background/AimsColorectal cancer, one of the most common cancers in developed countries, is curable when diagnosed at an early stage. However, for better screening, both a test that patients will tolerate and diagnostic accuracy are required. We compared patient experiences an..
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Original Article
Gemcitabine, Etoposide, Cisplatin, and Dexamethasone in Patients With Refractory or Relapsed Non-Hodgkin's Lymphoma
Ki-Hyang Kim, Young-Don Joo, Chang-Hak Sohn, Ho-Jin Shin, Joo-Seop Chung, Goon-Jae Cho, Sung-Hoon Shin, Yang-Soo Kim, Won-Sik Lee
Korean J Intern Med. 2009;24(1):37-42. Published online March 6, 2009
Background/AimsTo date, an effective salvage chemotherapy regimen for the treatment of refractory or relapsing non-Hodgkin's lymphoma (NHL) has not been discovered. This study was conducted to evaluate the efficacy and safety of gemcitabine, etoposide, cisplatin, and dexametha..
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Original Article
Clinical Features and Prognostic Factors of Anaerobic Infections: A 7-Year Retrospective Study
Yoonseon Park, Jun Young Choi, Dongeun Yong, Kyungwon Lee, June Myung Kim
Korean J Intern Med. 2009;24(1):13-18. Published online March 6, 2009
Background/AimsRisk factors for mortality resulting from anaerobic infection are incompletely defined. The clinical significance of a broad range of pathogenic obligate anaerobic organisms was examined, and factors independently associated with mortality were identified in pat..
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Case Report
A case of granulomatous lung disease in a patient with Good's syndrome
Seung Heon Lee, Sang-Min Lee, Seok-Chul Yang, Chul-Gyu Yoo, Young Whan Kim, Young-Soo Shim, Sung Koo Han
Korean J Intern Med. 2008;23(4):219-222. Published online December 30, 2008
Good's syndrome is extremely rare. This adult-onset condition is characterized by a thymoma with immunodeficiency, low B- and T-cell counts, and hypo-gammaglobulinemia. The initial clinical presentation is either a mass-lesion thymoma or a recurrent infection. Patients with Good's syndrome are ve..
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Case Report
A case of congenital bilateral coronary-to-right ventricle fistula coexisting with variant angina
Se-Na Jang, Sung-Ho Her, Kyong-Rock Do, Joon-Sung Kim, Hee-Jeong Yoon, Jong-Min Lee, Seung-Won Jin
Korean J Intern Med. 2008;23(4):216-218. Published online December 30, 2008
A coronary arteriovenous (AV) fistula consists of a communication between a coronary artery and a cardiac chamber, a great artery or the vena cava. It is the most common anomaly that can affect coronary perfusion. Yet bilateral involvement of a coronary fistula, constitutes an uncommon subgroup o..
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Original Article
Polymorphism in the promoter region of the klotho gene (G-395A) is associated with early dysfunction in vascular access in hemodialysis patients
Youngsu Kim, Sun Joo Jeong, Hyung Suk Lee, Eun Jung Kim, Young Rim Song, Sung Gyun Kim, Ji Eun Oh, Young Ki Lee, Jang Won Seo, Jong Woo Yoon, Ja-Ryong Koo, Hyung Jik Kim, Jung Woo Noh, Seung Ho Park
Korean J Intern Med. 2008;23(4):201-207. Published online December 30, 2008
Background/AimsVascular access dysfunction is an important cause of morbidity and mortality in hemodialysis (HD) patients. Recent studies have shown that a klotho gene mutation is related to endothelial dysfunction, thrombosis, and arteriosclerosis, which are ..
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Original Article
Autologous stem cell transplantation for diffuse large B-cell lymphoma with residual extranodal involvement
Ock Bae Ko, Geundoo Jang, Shin Kim, Jooryung Huh, Cheolwon Suh
Korean J Intern Med. 2008;23(4):182-190. Published online December 29, 2008
Background/AimsDiffuse large B-cell lymphoma (DLBCL) in Koreans is frequently accompanied by extranodal (EN) disease at the time of autologous stem cell transplantation (ASCT). We sought to determine whether high EN involvement affected survival following ASCT in Koreans. <..
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Original Article
Effects of dehydroepiandrosterone on Th2 cytokine production in peripheral blood mononuclear cells from asthmatics
Inseon S. Choi, Yong Cui, Young-Ah Koh, Hyun-Chul Lee, Yong-Bum Cho, Young-Ho Won
Korean J Intern Med. 2008;23(4):176-181. Published online December 30, 2008
Background/AimsThe androgen dehydroepiandrosterone (DHEA) attenuates allergic inflammatory airway reactions by down-regulating the Th2 response in mice. The purpose of this study was to investigate whether DHEA suppresses Th2 cytokine production in cultured peripheral blood m..
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