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Case Report
A Case of Behçet's Disease with Pericarditis, Thrombotic Thrombocytopenic Purpura, Deep Vein Thrombosis and Coronary Artery Pseudo Aneurysm
Chang Mo Kwon, Seung Hyun Lee, Jin Ho Kim, Kyu Hyung Lee, Hyun Do Kim, Yeong Hoon Hong, Choong Ki Lee
Korean J Intern Med. 2006;21(1):50-56. Published online March 30, 2006
Behçet's disease with concomitant thrombotic thrombocytopenic purpura (TTP), coronary artery stenosis and coronary artery pseudo aneurysm is rare. Here we report a case of Behçet's disease with several cardiovascular complications, namely: pericarditis, deep vein thrombosis (DVT), TTP, coronary..
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Case Report
Non-Hodgkin's Lymphoma Manifest as Gingival Hyperplasia in a Renal Transplant Recipient
Jung Hyun Kwon, Joon Chang Song, Sang Hun Lee, So Young Lee, Chul Woo Yang, Yong Soo Kim, Byung Kee Bang
Korean J Intern Med. 2005;20(4):330-334. Published online December 31, 2005
Gingival hyperplasia is a frequent complication in transplant patients who receive cyclosporine or calcium channel blockers. We studied an unusual case involving a renal transplant recipient with post-transplant non-Hodgkin's lymphoma that manifested as gingival hyperplasia. We initially consider..
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Original Article
Clinical Study of Adrenal Incidentaloma in Korea
Hee Young Kim, Sin Gon Kim, Kye Won Lee, Ji A Seo, Nan Hee Kim, Kyung Mook Choi, Sei Hyun Baik, Dong Seop Choi
Korean J Intern Med. 2005;20(4):303-309. Published online December 31, 2005
BackgroundThis study was designed to evaluate the clinical, endocrinological and histological characteristics of adrenal incidentalomas. MethodsEighty patients (41, males; 38, females; age range 17-80 years) who were diagnosed with adrenal incid..
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Case Report
Clear Cell Hepatocellular Carcinoma with Spontaneous Regression of Primary and Metastatic Lesions
Seong-Woo Jeon, Myung-Kwon Lee, Young-Doo Lee, Hyang-Eun Seo, Chang-Min Cho, Won-Young Tak, Young-Oh Kweon
Korean J Intern Med. 2005;20(3):268-273. Published online September 30, 2005
The prognosis of advanced hepatocellular carcinoma (HCC) tends to be poor. Spontaneous regression of this lesion is extremely rare. In this report, we describe a case of HCC which spontaneously regressed along with a metastatic lesion of the chest wall. A huge HCC in the right lobe, the largest ..
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Case Report
Cutaneous Metastases of Pancreatic Carcinoma as a First Clinical Manifestation
Dae Won Jun, Oh Young Lee, Chan Kum Park, Ho Soon Choi, Byung Chul Yoon, Min Ho Lee, Dong Hoo Lee
Korean J Intern Med. 2005;20(3):260-263. Published online September 30, 2005
Cutaneous metastases from pancreatic adenocarcinomas are rare lesions. The most common site of cutaneous metastasis is the umbilicus, and this is also known as the 'Sister Mary Joseph' nodule. A 68-year-old Korean male, who was previously healthy and asymptomatic, was seen in the dermatology depa..
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Original Article
Effect of High-Dose Intravenous N-acetylcysteine on the Concentration of Plasma Sulfur-Containing Amino Acids
Sae-Yong Hong, Hyo-Wook Gil, Jong-Oh Yang, Eun-Young Lee, Hyung-Kee Kim, Soo-Hyun Kim, Young-Ho Chung, Eun-Mi Lee, Soo-Kyung Hwang
Korean J Intern Med. 2005;20(3):217-223. Published online September 30, 2005
BackgroundThe purpose of this study was to determine the adequate loading and maintenance doses of N-acetylcyseteine (NAC) for patients suffering from acute ROS-induced injury. MethodsConcentrations of extra cellular NAC, cysteine (Cys), cystine..
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Original Article
Irinotecan, Continuous 5-Fluorouracil, and Low dose of Leucovorin (modified FOLFIRI) as First Line of Therapy in Recurrent or Metastatic Colorectal Cancer
Myung-Ah Lee, Jae-Ho Byun, Byoung-Young Shim, In-Sook Woo, Jin-Hyung Kang, Young Seon Hong, Kyung Shik Lee, Myung Gyu Choi, Suk Kyun Chang, Seong Taek Oh, Sung Il Choi, Doo Suk Lee
Korean J Intern Med. 2005;20(3):205-209. Published online September 30, 2005
BackgroundIrinotecan, in combination with 5-fluorouracil (5-FU) and a high dose of leucovorin (LV), known as FOLFIRI regimen, has shown activity in recurrent or metastatic colorectal cancer. Therefore, we evaluated the efficacy and safety of irinotecan, 5-FU and a low dose of ..
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Original Article
Expression of Cyclooxygenase-2 and Bcl-2 in Human Gastric Adenomas
Jee Hyun Park, Kyung Hee Kang, Se Hwan Kim, Jong Hyup Lee, Chang Min Cho, Young Oh Kweon, Sung Kook Kim, Yong Hwan Choi, Han Ik Bae, Mi Sung Kim
Korean J Intern Med. 2005;20(3):198-204. Published online September 30, 2005
BackgroundCyclooxygenase (COX)-2 is the rate-limiting enzyme in prostaglandin synthesis. An increased expression has been implicated in the development and progression of human gastric cancers and colorectal adenomas and cancers. This study aimed to determine the involvement a..
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Original Article
Clinicopathologic Significance of Gastric and Intestinal Phenotypic Marker Expression in Gastric Carcinomas
Gwang Ha Kim, Geun Am Song, Do Youn Park, Dong Hyun Lee, Tae Oh Kim, Seong Hun Lee, Jeong Heo, Dae Hwan Kang, Mong Cho
Korean J Intern Med. 2005;20(3):191-197. Published online September 30, 2005
BackgroundIt is well known that both gastric and intestinal phenotypic cell markers are expressed in gastric cancers. This study was aimed at investigating the correlation between gastric and intestinal phenotypic marker expression patterns of tumors and the clinicopathologic ..
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Case Report
Percutaneous Transluminal Coronary Angioplasty for Coronary Artery Stenosis in a Young Patient with Long Term Kawasaki Disease
Seok In Hong, Pum Joon Kim, Ki Bae Seung, Jung Hyun Kwon, Ju Yeal Beak, Chang Dong Yeo, Kyu Bo Choi
Korean J Intern Med. 2005;20(2):187-190. Published online June 30, 2005
Kawasaki Disease (KD) is an acute, febrile, multisystem disease of children. More severe complications in 15~25% of cases include, the development of coronary aneurysms, ischemic heart disease, and sudden cardiac death. The standard treatment for significant coronary artery stenosis has generally..
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Case Report
A Case of Primary Plasmacytoma of Lymph Nodes
Young Hyo Lim, Su Kyoung Park, Ho Suk Oh, Jung Hye Choi, Myung Ju Ahn, Young Yul Lee, In Soon Kim
Korean J Intern Med. 2005;20(2):183-186. Published online June 30, 2005
Extramedullary plasmacytoma may originate in any organ, either as a primary tumor or as a facet of systemic multiple myeloma. These solid lesions most commonly affect the upper respiratory tract, gastrointestinal and urogenital tract, skin, and lung. Primary plasmacytoma of the lymph node is a ra..
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Case Report
Eosinophilic Fasciitis Associated with Autoimmune Thyroiditis
Jin-Wuk Hur, Hye-Soon Lee, Wan-Sik Uhm, Jae-Bum Jun, Sang-Cheol Bae, Chan-Kum Park, Dae-Hyun Yoo
Korean J Intern Med. 2005;20(2):180-182. Published online June 30, 2005
Eosinophilic fasciitis (EF) is scleroderma-like disease without Raynaud's phenomenon or visceral involvement. It is characterized by painful swelling of the extremities, accompanied by rapid weight gain, fever and myalgia. The acute state of disease is associated with significant peripheral blood..
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Case Report
A Case of Erythema Nodosum and Serositis Associated with Myelodysplastic Syndrome
Jung-Hye Choi, Myung-Ju Ahn, Yong-Wook Park, Ho-Suk Oh, Young-Yeul Lee, In-Soon Kim
Korean J Intern Med. 2005;20(2):177-179. Published online June 30, 2005
Myelodysplastic syndrome (MDS) is a heterogenous group of stem cell disorders usually characterized by progressive refractory cytopenias, which could progress to acute myeloid leukemia. MDS may be associated with a wide spectrum of skin lesions, including neoplastic cell infiltration, Sweet's syn..
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Case Report
Kimura's Disease Involving Thoracic and Abdominal Lymph Nodes in a Hemodialysis Patient
Sik Lee, Su Jin Jung, Sung Kwang Park, Kyung Pyo Kang, Kyu Yun Jang, Myoung Jae Kang, Won Kim
Korean J Intern Med. 2005;20(2):159-162. Published online June 30, 2005
We report the first observed case of Kimura's disease occurring during hemodialysis, involving the thoracic and abdominal lymph nodes, which spontaneously resolved nearly completely after two months. Early diagnosis and recognition of Kimura's disease may spare both the patient and doctor from th..
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Original Article
The Effects of Methylene Blue on Hemodynamic Parameters and Cytokine Levels in Refractory Septic Shock
Byung-Kyu Park, Tae-Sun Shim, Chae-Man Lim, Sang-Do Lee, Woo-Sung Kim, Dong-Soon Kim, Won-Dong Kim, Younsuck Koh
Korean J Intern Med. 2005;20(2):123-128. Published online June 30, 2005
Background/AimsEndogenous nitric oxide (NO) induces the peripheral vasodilation via the activation of guanylate cyclase in patients with septic shock. The purpose of this study was to assess the acute effects of methylene blue (MB), which is an inhibitor of guanylate cyclase, ..
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Original Article
Comparison of the Clinical Features of Apical Hypertrophic Cardiomyopathy Versus Asymmetric Septal Hypertrophy in Korea
Hyun Suk Yang, Jae-Kwan Song, Jong-Min Song, Duk-Hyun Kang, Cheol Whan Lee, Myeong-Ki Hong, Jae-Joong Kim, Seong-Wook Park, Seung-Jung Park
Korean J Intern Med. 2005;20(2):111-115. Published online June 30, 2005
BackgroundWe sought to test whether patients with apical hypertrophic cardiomyopathy (APH) have different clinical features compared to those with typical asymmetric septal hypertrophy (ASH). MethodsAmong 32,534 patients who underwent routine ec..
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Case Report
Acute Exacerbation of Hepatitis in Liver Cirrhosis with Very High Levels of alpha-Fetoprotein But No Occurrence of Hepatocellular Carcinoma
Jin Soo Bae, Sang Jong Park, Kwang Bo Park, So Ya Paik, Jin Kyung Ryu, Chang Kyu Choi, Tae Joon Hwang
Korean J Intern Med. 2005;20(1):80-85. Published online March 31, 2005
Aminotransferase levels do not always increase during acute hepatitis or during an acute flare-up of chronic hepatitis. Persistently increased levels of serum alpha-Fetoprotein in an adult with liver disease suggest not only the presence or progression of hepatocellular carcinoma or its recurrenc..
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Case Report
Ileovesical Fistula Caused by Hepatocellular Carcinoma
Jeong Rae Byun, Sang Hee Cho, Deok Hwan Yang, Yeo Kyeoung Kim, Jae Kyun Ju, Sung Kyu Choi, Ik Joo Chung
Korean J Intern Med. 2005;20(1):76-79. Published online March 31, 2005
Ileovesical fistula is a very rare clinical entity, the most frequent cause of which is Crohn's disease. Furthermore, it is an exceptionally rare complication of malignancies. We experienced one case of ileovesical fistula which had been caused by hepatocellular carcinoma (HCC) arising from the n..
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Case Report
Solitary Intra-abdominal Tuberculous Lymphadenopathy Mimicking Duodenal GIST
You Sun Kim, Jeong Seop Moon, Jung Whan Lee, Il Kim, Soo Hyung Ryu, In Wook Paik
Korean J Intern Med. 2005;20(1):72-75. Published online March 31, 2005
Tuberculosis remains prevalent in developing countries and has recently re-emerged in the Western world. Intra-abdominal tuberculosis can mimic a variety of other abdominal disorders, and here we describe a patient with solitary tuberculous mesenteric lymphadenopathy mimicking duodenal gastrointe..
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Case Report
Cases of Swallow Syncope Induced by the Activation of Mechanorecepters in the Lower Esophagus
Ki Hoon Kang, Wook Hyun Cho, Myung Chan Kim, Hee Jong Chang, Jae Il Chung, Dong Jun Won
Korean J Intern Med. 2005;20(1):68-71. Published online March 31, 2005
Swallowing is a rare cause of neurally mediated syncope. The mechanism of swallow syncope that contributes to hypotension, bradycardia, or to both is complex. A 59-year-old man had experienced a recurrent loss of consciousness during swallowing of carbonated beverages or sticky foods. Another 59-..
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