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Pulmonology / Original Article
Proteomic differences with and without ozone-exposure in a smoking-induced emphysema lung model
Soo-Taek Uh, So-My Koo, An Soo Jang, Sung Woo Park, Jae Sung Choi, Yong-Hoon Kim, Choon Sik Park
Korean J Intern Med. 2015;30(1):62-72. Published online December 30, 2014
Background/Aims: Acute exacerbations in chronic obstructive pulmonary disease may be related to air pollution, of which ozone is an important constituent. In this study, we investigated the protein profiles associated with ozone-induced exacerbations in a smoking-induced emphysema model.
Methods: M..
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Pulmonology / Original Article
Pleural fluid characteristics of pleuropulmonary paragonimiasis masquerading as pleural tuberculosis
Ki-Eun Hwang, Hyo-Yeop Song, Jae-Wan Jung, Su-Jin Oh, Kwon-Ha Yoon, Do-Sim Park, Eun-Taik Jeong, Hak-Ryul Kim
Korean J Intern Med. 2015;30(1):56-61. Published online December 30, 2014
Background/Aims: Pleuropulmonary paragonimiasis produces no specific symptoms or radiologic findings, allowing for the possibility of misdiagnosis. We evaluated the specific clinical and pleural fluid features of pleuropulmonary paragonimiasis masquerading as pleural tuberculosis.
Methods: We retro..
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Cardiology / Original Article
Clinical impact of routine follow-up coronary angiography after second- or third-generation drug-eluting stent insertion in clinically stable patients
Seonghoon Choi, Hee-Sun Mun, Min-Kyung Kang, Jung Rae Cho, Seong Woo Han, Namho Lee Lee
Korean J Intern Med. 2015;30(1):49-55. Published online December 30, 2014
Background/Aims: In the bare-metal stent era, routine follow-up coronary angiography (RFU CAG) was used to ensure stent patency. With the advent of drug-eluting stents (DESs) with better safety and efficacy profiles, RFU CAG has been performed less often. There are few data on the clinical impact of..
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Rheumatology / Review
Methods for the morphological and functional evaluation of microvascular damage in systemic sclerosis
Barbara Ruaro, Vanessa Smith, Alberto Sulli, Saskia Decuman, Carmen Pizzorni, Maurizio Cutolo
Korean J Intern Med. 2015;30(1):1-5. Published online December 30, 2014
Systemic sclerosis is a connective tissue disease characterized by alterations in microvascular structure and function. In these patients, numerous studies have demonstrated a relationship between capillary morphology and peripheral blood perfusion. Nailfold videocapillaroscopy reveals the periphera..
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Letter to the editor
Parvimonas micra chest wall abscess following transthoracic lung needle biopsy
Luis Gorospe, Isabel Bermudez-Coronel-Prats, Carol F. Gomez-Barbosa, Maria E. Olmedo-Garcia, Angel Ruedas-Lopez, Vicente Gomez del Olmo
Korean J Intern Med. 2014;29(6):834-837. Published online October 31, 2014
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Letter to the editor
Graves’ disease presenting with acute renal infarction
Cho-Ok Baek, Kyung Ae Lee, Tae Sun Park, Heung Yong Jin
Korean J Intern Med. 2014;29(6):825-826. Published online October 31, 2014
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Letter to the editor
Funtional significance of the intermediate lesion in a single coronary artery assessed by fractional flow reserve
Sang Jin Ha, Se Hwan Kwon, Soo-Joong Kim
Korean J Intern Med. 2014;29(6):822-824. Published online October 31, 2014
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Rheumatology / Original Article
Complex repetitive discharge on electromyography as a risk factor for malignancy in idiopathic inflammatory myopathy
Na Ri Kim, Eon Jeong Nam, Jong Wan Kang, Hyun Seok Song, Churl Hyun Im, Young Mo Kang
Korean J Intern Med. 2014;29(6):814-821. Published online October 31, 2014
Background/Aims: We investigated the electromyography (EMG) findings and demographic, clinical, and laboratory features that may predict the development of malignancy in patients with idiopathic inflammatory myopathy (IIM).
Methods: In total, 61 patients, 36 with dermatomyositis and 25 with polymyo..
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Allergy / Original Article
Clinical features of elderly chronic urticaria
Ga-Young Ban, Mi-Yea Kim, Hye-Soo Yoo, Dong-Ho Nahm, Young-Min Ye, Yoo-Seob Shin, Hae-Sim Park
Korean J Intern Med. 2014;29(6):800-806. Published online October 31, 2014
Background/Aims: Chronic urticaria (CU) is defined as itchy wheals lasting 6 weeks or more. As the aged population increases worldwide, it is essential to identify the specific features of this disease in the elderly population.
Methods: We investigated the prevalence and clinical features of CU in..
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Cardiology / Original Article
The diagnostic utility of chest computed tomography scoring for the assessment of amiodarone-induced pulmonary toxicity
In Sook Kang, Kyung Jin Kim, Yookyung Kim, Seong-Hoon Park
Korean J Intern Med. 2014;29(6):746-753. Published online October 31, 2014
Background/Aims: Amiodarone is one of the most widely used antiarrhythmic agents; however, amiodarone-induced pulmonary toxicity (APT) can be irreversible and sometimes fatal. The aim of this study was to evaluate the feasibility of chest computed tomography (CT) as a diagnostic tool for APT and to ..
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Hemato-oncology / Review
Recent advances in treatment of aplastic anemia
Seung Hwan Shin, Sung Eun Lee, Jong Wook Lee
Korean J Intern Med. 2014;29(6):713-726. Published online October 31, 2014
Recent advances in the treatment of aplastic anemia (AA) made most of patients to expect to achieve a long-term survival. Allogeneic stem cell transplantation (SCT) from HLA-matched sibling donor (MSD-SCT) is a preferred first-line treatment option for younger patients with severe or very severe AA,..
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Cardiology / Review
The scientific achievements of the decades in Korean Acute Myocardial Infarction Registry
Hyun Kuk Kim, Myung Ho Jeong, Seung Hun Lee, Doo Sun Sim, Young Joon Hong, Youngkeun Ahn, Chong Jin Kim, Myeong Chan Cho, Young Jo Kim
Korean J Intern Med. 2014;29(6):703-712. Published online October 31, 2014
The Korea Acute Myocardial Infarction Registry (KAMIR) was the first nationwide registry data collection designed to track outcomes of patients with acute myocardial infarction (AMI). These studies ref lect the current therapeutic approaches and management for AMI in Korea. The results of KAMIR coul..
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Cardiology / Review
Role of modern 3D echocardiography in valvular heart disease
Takahiro Shiota
Korean J Intern Med. 2014;29(6):685-702. Published online October 31, 2014
Three-dimensional (3D) echocardiography has been conceived as one of the most promising methods for the diagnosis of valvular heart disease, and recently has become an integral clinical tool thanks to the development of high quality real-time transesophageal echocardiography (TEE). In particular, fo..
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Hemato-oncology / Original Article
Etanercept for steroid-refractory acute graft versus host disease following allogeneic hematopoietic stem cell transplantation
Joo Han Park, Hyo Jung Lee, Sei Rhan Kim, Ga Won Song, Seung Kyong Lee, Sun Young Park, Ki Chan Kim, Sun Hyuk Hwang, Joon Seong Park
Korean J Intern Med. 2014;29(5):630-636. Published online August 28, 2014
Background/Aims: The treatment for steroid-refractory acute graft versus host disease (GVHD) after allogeneic stem cell transplantation (allo-SCT) needs to be standardized. We report our clinical experience with etanercept for steroid-refractory acute GVHD.
Methods: Eighteen patients who underwent ..
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Pulmonology / Original Article
Factors predictive of the failure of medical treatment in patients with pleural infection
Sung-Kyoung Kim, Chul Ung Kang, So Hyang Song, Deog Gon Cho, Kyu Do Cho, Chi Hong Kim
Korean J Intern Med. 2014;29(5):603-612. Published online August 28, 2014
Background/Aims: The clinical outcomes of some patients with pleural infection may be favorable with medical treatment alone, but in others, the disease progresses and requires additional surgical treatment. However, little is known about the factors affecting this difference. The aim of this study ..
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Gastroenterology / Original Article
A novel prognostic factor for hepatocellular carcinoma: protein disulfide isomerase
Su Jong Yu, Jae-Kyung Won, Han Suk Ryu, Won-Mook Choi, Hyeki Cho, Eun-Ju Cho, Jeong-Hoon Lee, Yoon Jun Kim, Kyung-Suk Suh, Ja-June Jang, Chung Yong Kim, Hyo-Suk Lee, Jung-Hwan Yoon, Kwang-Hyun Cho
Korean J Intern Med. 2014;29(5):580-587. Published online August 28, 2014
Background/Aims: Protein disulfide isomerase (PDI) has been implicated in the survival and progression of some cancer cells, by compensating for endoplasmic reticulum stress by upregulating the protein-folding capacity. However, its prognostic role in patients with hepatocellular carcinoma (HCC) has..
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Cardiology / Review
Recent technological updates and clinical applications of induced pluripotent stem cells
Sebastian Diecke, Seung Min Jung, Jaecheol Lee, Ji Hyeon Ju
Korean J Intern Med. 2014;29(5):547-557. Published online August 28, 2014
Induced pluripotent stem cells (iPSCs) were first described in 2006 and have since emerged as a promising cell source for clinical applications. The rapid progression in iPSC technology is still ongoing and directed toward increasing the efficacy of iPSC production and reducing the immunogenic and t..
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Letter to the editor
Recurrent neutropenia induced by rifabutin in a renal transplant recipient
Ji Yeun Chang, Eun Gyo Jeong, Ji Hyun Yu, Byung Ha Chung, Chul Woo Yang
Korean J Intern Med. 2014;29(4):532-534. Published online June 27, 2014
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Letter to the editor
A case of myocardial involvement in lung cancer that mimics ST segment elevation in myocardial infarction
Kye Hun Kim, Myung Ho Jeong, Hyun Ju Yoon, Youngkeun Ahn, Jeong Gwan Cho, Jong Chun Park, Jung Chaee Kang
Korean J Intern Med. 2014;29(4):525-528. Published online June 27, 2014
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Nephrology / Original Article
Effects of pretransplant plasmapheresis and rituximab on recurrence of focal segmental glomerulosclerosis in adult renal transplant recipients
Hoon Suk Park, Yuah Hong, In O Sun, Byung Ha Chung, Hyung Wook Kim, Bum Soon Choi, Cheol Whee Park, Dong Chan Jin, Yong Soo Kim, Chul Woo Yang
Korean J Intern Med. 2014;29(4):482-488. Published online June 27, 2014
Background/Aims: Recurrent focal segmental glomerulosclerosis (FSGS) following renal transplantation is relatively common. However, the risk factors and optimal pretransplant treatment preventing recurrence of FSGS remain controversial.
Methods: We retrospectively reviewed 27 adult renal transplan..
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