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Rheumatology / Original Article
Reclassification of the overlap syndrome of Behçet’s disease and antineutrophil cytoplasmic antibody-associated vasculitis in patients with Behçet’s disease
Tae Geom Lee, Jang Woo Ha, Jason Jungsik Song, Yong-Beom Park, Sang-Won Lee
Korean J Intern Med. 2025;40(1):135-147. Published online January 1, 2025
Background/Aims: This study applied the 2022 American College of Rheumatology/European Alliance of Associations for Rheumatology (ACR/EULAR) criteria for antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) to patients with Behçet’s disease (BD) to investigate the proportion and..
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Hemato-oncology / Original Article
Reduced-intensity chemotherapy with tyrosine kinase inhibitor followed by allogeneic transplantation is effective in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia
Jung Min Lee, Do Young Kim, Hee Jeong Cho, Joon Ho Moon, Sang Kyun Sohn, Ho Jin Shin, Young Rok Do, Mi Hwa Heo, Min Kyoung Kim, Young Seob Park, Dong Won Baek
Korean J Intern Med. 2025;40(1):124-134. Published online January 1, 2025
Background/Aims: To determine the effectiveness of tyrosine kinase inhibitor (TKI) plus reduced-intensity therapy in adult patients with newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph-positive ALL), this retrospective study compared treatment outcomes and induction..
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Hemato-oncology / Original Article
The characteristics of Korean elderly multiple myeloma patients aged 80 years or over
Sang Hwan Lee, Hee-Jeong Cho, Joon Ho Moon, Ji Yoon Jung, Min Kyoung Kim, Mi Hwa Heo, Young Rok Do, Yunhwi Hwang, Sung Hwa Bae
Korean J Intern Med. 2025;40(1):115-123. Published online January 1, 2025
Background/Aims: Multiple myeloma (MM) predominantly affects elderly individuals, but studies on older patients with MM are limited. The clinical characteristics and survival outcomes of patients with MM aged 80 years or over were retrospectively analyzed.
Methods: This retrospective multicenter st..
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Endocrinology-metabolism / Original Article
Fisher discriminant analysis of multimodal ultrasound in diagnosis of cervical metastatic lymph nodes in papillary thyroid cancer
Yixuan Wang, Yue Han, Fei Li, Yuyang Lin, Bei Wang
Korean J Intern Med. 2025;40(1):103-114. Published online October 29, 2024
Background/Aims: The purpose of this study was to develop a diagnostic model utilizing multimodal ultrasound parameters to aid in the detection of cervical lymph node metastasis in papillary thyroid cancer (PTC) patients.
Methods: The study included 84 suspicious lymph nodes from 69 PTC patients, a..
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Endocrinology-metabolism / Original Article
Dexamethasone synergizes with high-fat diet to increase lipid deposition in adipocytes
Mingli Su, Ying Wang, Zheng Yan, Jia Luo, Jie Yang, Hua Ye, Aiming Liu, Julin Yang
Korean J Intern Med. 2025;40(1):92-102. Published online January 1, 2025
Background/Aims: Dexamethasone (DEX) is a widely used exogenous therapeutic glucocorticoid in clinical settings. Its long-term use leads to many side effects. However, its effect on metabolic disorders in individuals on a high-fat diet (HFD) remains poorly understood.
Methods: In this study, HFD-fe..
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Pulmonology / Original Article
Blood eosinophil count and treatment patterns of chronic obstructive pulmonary disease patients in South Korea using real-world data
Chin Kook Rhee, Yu-Fan Ho, Sumitra Shantakumar, Tim Holbrook, Yein Nam, Kwang‑Ha Yoo
Korean J Intern Med. 2025;40(1):78-91. Published online January 1, 2025
Background/Aims: Chronic obstructive pulmonary disease (COPD) management guidelines have increasingly emphasised the importance of exacerbation prevention, and the role of blood eosinophil count (BEC) as a biomarker for inhaled corticosteroids (ICS) response. This study aimed to describe the distrib..
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Cardiology / Original Article
Predictive value and optimal cut-off level of high-sensitivity troponin T in patients with acute pulmonary embolism
Moojun Kim, Chang-Ok Seo, Yong-Lee Kim, Hangyul Kim, Hye Ree Kim, Yun Ho Cho, Jeong Yoon Jang, Jong-Hwa Ahn, Min Gyu Kang, Kyehwan Kim, Jin-Sin Koh, Seok-Jae Hwang, Jin Yong Hwang, Jeong Rang Park
Korean J Intern Med. 2025;40(1):65-77. Published online January 1, 2025
Background/Aims: Elevated troponin levels predict in-hospital mortality and influence decisions regarding thrombolytic therapy in patients with acute pulmonary embolism (PE). However, the usefulness of high-sensitivity troponin T (hsTnT) regarding PE remains uncertain. We aimed to establish the opti..
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Gastroenterology / Original Article
Association between acid-suppressive drugs and risk of psoriasis: retrospective study using Korean National Health Insurance Service-National Sample Cohort
Ji Hyun Kim, Joon-hong Min, Young Woo Jo, Jae Woo Kwon, Young Her
Korean J Intern Med. 2025;40(1):57-64. Published online January 1, 2025
Background/Aims: Psoriasis is a common inflammatory skin disorder following non-specific triggers. Involvement of immune system is widely accepted for pathogenesis studies have demonstrated importance of gut microbiota in pathogenesis of inflammatory skin diseases. Proton pump inhibitor (PPI) and hi..
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Gastroenterology / Original Article
Incidence and risk factors of immune checkpoint inhibitor-induced colitis in Korean patients with cancer
Tae Kyun Kim, Hyun Seok Lee, Eun Soo Kim
Korean J Intern Med. 2025;40(1):49-56. Published online January 1, 2025
Background/Aims: Immune checkpoint inhibitors (ICIs) are effective in treating cancer. However, various immune-related adverse events (irAEs) have become prevalent, with ICI-induced colitis being the most common gastrointestinal irAE. Thus, we aimed to investigate the incidence and risk factors of I..
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Rheumatology / Review
Literature review of non-pharmacological treatment for patients with axial spondyloarthritis
Jina Yeo, Mi Ryoung Seo, Jun Won Park, Yeon-Ah Lee, Ju Ho Lee, Eun Ha Kang, Seon Mi Ji, Han Joo Baek
Korean J Intern Med. 2025;40(1):40-48. Published online May 27, 2024
Axial spondyloarthritis (axSpA) is a chronic inflammatory disorder affecting the sacroiliac joints and axial spine. Along with pharmacotherapy, non-pharmacological interventions for axSpA are crucial and constitute the cornerstone of treatment. Here, we review the evidence for non-pharmacological tr..
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Endocrinology-metabolism / Review
Bariatric surgery for treatment of morbid obesity in adults
Ki Bum Park, Kyong-Hwa Jun
Korean J Intern Med. 2025;40(1):24-39. Published online January 1, 2025
Morbid obesity requires active intervention, with treatment options including lifestyle modification, pharmacotherapy, and surgery. As the prevalence of obesity continues to rise in Korea, it is crucial for specialists and general practitioners to have a comprehensive understanding of obesity and it..
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Cardiology / Review
Current status of modifiable risk factors for cardiovascular disease in Korean women
In-Jeong Cho, Mi-Seung Shin
Korean J Intern Med. 2025;40(1):15-23. Published online October 22, 2024
Hypertension, diabetes mellitus, dyslipidemia, obesity, and smoking are the primary modifiable risk factors contributing to the increasing morbidity and mortality rates from cardiovascular disease (CVD) among Korean women. Significant sex-related differences exist in the prevalence, awareness, treat..
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Cardiology / Review
Screening and diagnosis of atrial fibrillation using wearable devices
Yoon Jung Park, Myung Hwan Bae
Korean J Intern Med. 2025;40(1):7-14. Published online May 3, 2024
In recent years, the development and use of various devices for the screening of atrial fibrillation (AF) have significantly increased. Such devices include 12-lead electrocardiogram (ECG), photoplethysmography systems, and single-lead ECG and ECG patches. This review outlines several studies that h..
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Gastroenterology / Editorial
Who is at risk for immune checkpoint inhibitor-induced colitis among Korean patients?
Ji Hyun Kim, Sung Chul Park
Korean J Intern Med. 2025;40(1):3-4. Published online January 1, 2025
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Reviewer
Deep appreciation to our reviewers in the past year
Korean J Intern Med. 2025;40(1):2-2. Published online January 1, 2025
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Editorial
KJIM update 2025
Hyoung-Chul Oh
Korean J Intern Med. 2025;40(1):1-1. Published online January 1, 2025
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Pulmonology / Image of interest
Effective control of a severely progressive recurrent respiratory papillomatosis with repetitive cryotherapy
Jae Seok Jeong, Jee Hee Lee, Jun Hyung Park, Yeong Hun Choe, Yong Chul Lee
Korean J Intern Med. 2024;39(6):1023-1024. Published online October 22, 2024
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Cardiology / Image of interest
Systemic venous air embolism after percutaneous lung biopsy
Min Kyung Jung, Shin Young Kim, Jeong Min Ko
Korean J Intern Med. 2024;39(6):1021-1022. Published online August 13, 2024
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Geriatrics / Original Article
A link between systemic low-grade inflammation and frailty in older adults: clinical evidence from a nationwide population-based study
Min-gu Kang, Hee-Won Jung, Beom-Jun Kim
Korean J Intern Med. 2024;39(6):1011-1020. Published online July 23, 2024
Background/Aims: Despite the possible role of systemic low-grade inflammation on frailty, the majority of previous studies have focused solely on the phenotypic frailty with limited participant numbers, thereby weakening the evidence supporting the notion that circulating C-reactive protein (CRP) co..
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