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Gastroenterology / Original Article
Diagnosis and management of acute colonic diverticulitis: results of a survey among Korean gastroenterologists
Jae Gon Lee, Yong Eun Park, Ji Young Chang, Hyun Joo Song, Duk Hwan Kim, Young Joo Yang, Byung Chang Kim, Shin Hee Lee, Myung-Won You, Seong-Eun Kim
Korean J Intern Med. 2023;38(5):672-682. Published online August 17, 2023
Background/Aims: Some management strategies for acute colonic diverticulitis remain controversial in Korean real-world practice because their clinical features differ from those in the West. This study aimed to investigate the opinions of Korean physicians regarding the diagnosis and treatment of ac..
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Gastroenterology / Original Article
Efficacy and safety of 1 L polyethylene glycol plus ascorbic acid for bowel preparation in elderly: comparison with oral sulfate solution
Ki Young Lim, Kyeong Ok Kim, Eun Young Kim, Yoo Jin Lee, Byung Ik Jang, Sung Kook Kim, Chang Heon Yang; on behalf of Crohn’s and Colitis Association in Daegu-Gyeongbuk (CCAiD)
Korean J Intern Med. 2023;38(5):651-660. Published online July 24, 2023
Background/Aims: Recently, 1 L of polyethylene glycol (PEG) plus ascorbic acid (Asc) has been introduced in Korea as a colonoscopy preparation agent. Data on its efficacy and safety in older adults have been limited. We aimed to evaluate the safety and efficacy of 1 L PEG/Asc in older adults by comp..
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Cardiology / Review
Role of cardiac imaging in management of heart failure
So Ree Kim, Seong-Mi Park
Korean J Intern Med. 2023;38(5):607-619. Published online August 29, 2023
The significant advancement in cardiac imaging in recent years led to improved diagnostic accuracy in identifying the specific causes of heart failure and also provided physicians with guidelines for appropriately managing patients with heart failure. Diseases that were once considered rare are now ..
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Geriatrics / Original Article
Predictors of 3-month mortality with muscle ultrasound and palliative prognostic tools among patients admitted to palliative care units
Zeynep Irmak Kaya, Yelda Öztürk, Sinem Gürcü, Gülgün Uncu, Anıl Uçan, Mert Eşme, Berrin Yalınbaş Kaya, Cafer Balci
Korean J Intern Med. 2023;38(4):557-565. Published online March 31, 2023
Background/Aims: Prognostic factors are an important issue in progressive and life-limiting diseases. This study evaluate 3-month mortality in patients admitted to the palliative care unit (PCU).
Methods: In this study, the patient’s demographics, comorbidities, nutritional status, and laboratory..
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Cardiology / Review
Role of echocardiography in acute pulmonary embolism
Jin Kyung Oh, Jae-Hyeong Park
Korean J Intern Med. 2023;38(4):456-470. Published online January 2, 2023
Although pulmonary embolism (PE)-related mortality rate has decreased because of prompt diagnosis and effective therapy use, acute PE remains a potentially lethal disease. Due to its increasing prevalence, clinicians should pay attention to diagnosing and managing patients with acute PE. Echocardiog..
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Gastroenterology / Original Article
Clinical and endoscopic characteristics of sessile serrated lesions with dysplasia/carcinoma
Peel Jung, Hyung Wook Kim, Su Bum Park, Dae Hwan Kang, Cheol Woong Choi, Su Jin Kim, Hyeong Seok Nam, Dae Gon Ryu, Dong Hoon Shin, Joo Young Na, Mi Sook Yun
Korean J Intern Med. 2023;38(3):349-361. Published online March 27, 2023
Background/Aims: Some sessile serrated lesions (SSLs) progress into dysplasia and colorectal cancer, however, the clinical and endoscopic characteristics of SSLs with dysplasia remain to be determined. In this study, we elucidated these characteristics in SSLs with dysplasia/carcinoma, compared with..
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Geriatrics / Original Article
The prognostic value of comprehensive geriatric assessment on the management of older patients with small cell lung cancer
You Jin Chun, Kwang Joon Kim, Ji Yeon Lee, Ji Won Choi, Tae Hee Kim, Hye Ryun Kim, Byoung Chul Cho, Min Hee Hong, Chang Oh Kim
Korean J Intern Med. 2023;38(2):254-263. Published online January 19, 2023
Background/Aims: The prognostic value of a comprehensive geriatric assessment (CGA) for the management of older small cell lung cancer (SCLC) patients remains to be established.
Methods: A retrospective cohort enrolled 21 SCLC patients over 65 years from March 2018 to 2019 at the Yonsei Cancer Cent..
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Pulmonology / Original Article
Real-world evaluation of atezolizumab and etoposide-carboplatin as a first-line treatment for extensive-stage small cell lung cancer
Soo Han Kim, Eun Jung Jo, Jeongha Mok, Kwangha Lee, Ki Uk Kim, Hye-Kyung Park, Min Ki Lee, Jung Seop Eom, Mi-Hyun Kim
Korean J Intern Med. 2023;38(2):218-225. Published online February 21, 2023
Background/Aims: Despite the obvious benefits of adding immune checkpoint inhibitors to platinum-etoposide chemotherapy in patients with extensive-stage small-cell lung cancer (ES-SCLC), real-world data remain scarce.
Methods: This retrospective study included 89 patients with ES-SCLC treated with ..
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Cardiology / Review
Obesity-related heart failure with preserved ejection fraction: diagnostic and therapeutic challenges
Mi-Hyang Jung, Mi-Seung Shin
Korean J Intern Med. 2023;38(2):157-166. Published online February 6, 2023
The prevalence of heart failure with preserved ejection fraction (HFpEF) has increased in recent decades. In particular, obesity-related HFpEF is a distinct and frequently encountered phenotype; however, its diagnosis is complex. Furthermore, the management of obesity-related HFpEF has not been esta..
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Endocrinology-metabolism / Original Article
Diabetes screening in South Korea: a new estimate of the number needed to screen to detect diabetes
Kyoung Hwa Ha, Kyung Ae Lee, Kyung-Do Han, Min Kyong Moon, Dae Jung Kim
Korean J Intern Med. 2023;38(1):93-100. Published online November 24, 2022
Background/Aims: The Korean Diabetes Association (KDA) guidelines recommend adults aged ≥ 40 years and adults aged ≥ 30 years with diabetes risk factors for diabetes screening. This study aimed to determine the age threshold for diabetes screening in Korean adults.
Methods: This study was based o..
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Gastroenterology / Original Article
Effect of age on the prognosis of intrahepatic cholangiocarcinoma
Jung Hun Kim, Young Koog Cheon, Tae Yoon Lee, Sang Hoon Lee, Hyunji Chung
Korean J Intern Med. 2023;38(1):39-47. Published online December 21, 2022
Background/Aims: Intrahepatic cholangiocarcinoma (iCCA) is a subgroup of cholangiocarcinoma and is the second- most-common primary hepatic tumor. Several predictive and prognostic factors have been analyzed; however, in this study we focused on the influence of age. Our aim was to use real-world res..
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Rheumatology / Review
Assessment and nonsurgical management of low back pain: a narrative review
Sung Cheol Park, Min-Seok Kang, Jae Hyuk Yang, Tae-Hoon Kim
Korean J Intern Med. 2023;38(1):16-26. Published online November 24, 2022
Low back pain (LBP) is a common condition that affects people of all ages and income levels worldwide. The etiology of LBP may be mechanical, neuropathic, systemic, referred visceral, or secondary to other causes. Despite numerous studies, the diagnosis and management of LBP remain challenging due to..
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Rheumatology / Original Article
Clinical impact of proteinase 3-antineutrophil cytoplasmic antibody positivity in eosinophilic granulomatosis with polyangiitis
Sung Soo Ahn, Jason Jungsik Song, Yong-Beom Park, Sang-Won Lee
Korean J Intern Med. 2022;37(6):1241-1249. Published online December 13, 2021
Background/Aims: This study investigated the clinical implication of proteinase 3 (PR3)-antineutrophil cytoplasmic antibody (ANCA) in Korean patients with eosinophilic granulomatosis with polyangiitis (EGPA).
Methods: Among the 242 patients with ANCA-associated vasculitis identified from the hospit..
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Gastroenterology / Original Article
Real-life experience of ledipasvir and sofosbuvir for HCV infected Korean patients: a multicenter cohort study
Soon Kyu Lee, Sung Won Lee, Hae Lim Lee, Hee Yeon Kim, Chang Wook Kim, Do Seon Song, U Im Chang, Jin Mo Yang, Sun Hong Yoo, Jung Hyun Kwon, Soon Woo Nam, Seok-Hwan Kim, Myeong Jun Song, Jaejun Lee, Hyun Yang, Si Hyun Bae, Ji Won Han, Heechul Nam, Pil Soo Sung, Jeong Won Jang, Jong Young Choi, Seung Kew Yoon
Korean J Intern Med. 2022;37(6):1167-1175. Published online May 27, 2022
Background/Aims: To evaluate the efficacy and safety of ledipasvir/sofosbuvir (LDV/SOF) therapy in hepatitis C virus (HCV)-infected Korean patients in a real clinical setting.
Methods: A total of 273 patients who received LDV/SOF therapy between May 2016 and February 2021 were consecutively enrolle..
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Gastroenterology / Original Article
The effect of rebamipide on non-steroidal anti-inflammatory drug-induced gastro-enteropathy: a multi-center, randomized pilot study
Dong Jun Oh, Hyuk Yoon, Hyun Soo Kim, Yoon Jin Choi, Cheol Min Shin, Young Soo Park, Nayoung Kim, Dong Ho Lee, You-Jung Ha, Eun Ha Kang, Yun Jong Lee, Nayoung Kim, Ki-Jeoung Kim, Fei Liu
Korean J Intern Med. 2022;37(6):1153-1166. Published online November 1, 2022
Background/Aims: Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly-used medications, and ailments such as arthritis or heart disease, require long-term use of these drugs, which can induce gastroenteropathy with bleeding and ulcers. This study investigated the associations between efficacy..
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Endocrinology-metabolism / Review
Musculoskeletal complications in patients with diabetes mellitus
Jong Han Choi, Hae-Rim Kim, Kee-Ho Song
Korean J Intern Med. 2022;37(6):1099-1110. Published online October 27, 2022
Musculoskeletal conditions are common in patients with diabetes. Several musculoskeletal disorders are viewed as chronic complications of diabetes because epidemiological studies have revealed high correlations between such complications and diabetes, but the pathophysiological links with diabetes r..
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Nephrology / Original Article
Insufficient early renal recovery and progression to subsequent chronic kidney disease in living kidney donors
Yaerim Kim, Eunjeong Kang, Dong-Wan Chae, Jung Pyo Lee, Sik Lee, Soo Wan Kim, Jang-Hee Cho, Miyeun Han, Seungyeup Han, Yong Chul Kim, Dong Ki Kim, Kwon Wook Joo, Yon Su Kim, Hajeong Lee
Korean J Intern Med. 2022;37(5):1021-1030. Published online April 13, 2022
Background/Aims: Renal recovery of a kidney donor after undergoing nephrectomy though challenging is essential. We aimed to examine the effect of estimated glomerular filtration rate (eGFR) percent change at 1-month post-donation on insufficient kidney function after kidney donation.
Methods: A tot..
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Endocrinology-metabolism / Original Article
The efficacy of denosumab in Korean male patients with osteoporosis
Chaiho Jeong, Jeonghoon Ha, Jinyoung Kim, Yejee Lim, Mee Kyoung Kim, Hyuk-Sang Kwon, Ki-Ho Song, Moo Il Kang, Ki-Hyun Baek
Korean J Intern Med. 2022;37(5):1011-1020. Published online June 3, 2022
Background/Aims: Despite the prominence of denosumab as the number one prescribed anti-osteoporosis drug in Korea, the effects of denosumab in male osteoporosis patients were not researched sufficiently. Moreover, concerns on rebound vertebral fractures associated with poor denosumab adherence exist..
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Gastroenterology / Original Article
Factors associated with the risk of colorectal neoplasia in young adults under age 40
Ilsoo Kim, Han Hee Lee, Young Jae Ko, Ho Eun Chang, Dae Young Cheung, Bo-In Lee, Young-Seok Cho, Jin Il Kim, Myung-Gyu Choi
Korean J Intern Med. 2022;37(5):969-978. Published online July 25, 2022
Background/Aims: Recent epidemiologic studies have shown a continued increase in colorectal cancer incidence among younger adults. Little is known about the factors that contribute to the development of young-onset colorectal neoplasia (CRN).
Methods: A cross-sectional analysis was performed for ind..
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Review
Updates on conventional therapies for inflammatory bowel diseases: 5-aminosalicylates, corticosteroids, immunomodulators, and anti-TNF-α
Jihye Park, Jae Hee Cheon
Korean J Intern Med. 2022;37(5):895-905. Published online July 27, 2022
The incidence and prevalence of inflammatory bowel diseases (IBDs) are rapidly increasing worldwide. IBDs are considered an emerging problem not only in Western countries but also in developing counties. The relapses and complications of active IBD mandate various medications. Nevertheless, hospital..
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