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Case Report
Postinfectious Guillain-Barre syndrome in a patient with methimazole-induced agranulocytosis
Yoon Young Cho, Ji Young Joung, Hyemin Jeong, Dongmo Je, Yun Soo Hong, Sunghwan Suh, Sun Wook Kim
Korean J Intern Med. 2013;28(6):724-727. Published online October 29, 2013
Both Graves disease and Guillain-Barre syndrome (GBS) are autoimmune disorders caused by impaired self-tolerance mechanisms and triggered by interactions between genetic and environmental factors. GBS in patients who suffer from other autoimmune diseases is rarely reported, and the development of..
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Case Report
Successful management of colonic perforation with a covered metal stent
Sang Woo Kim, Wook Hyun Lee, Jin Soo Kim, Ha Nee Lee, Soo Jung Kim, Seok Jong Lee
Korean J Intern Med. 2013;28(6):715-717. Published online October 29, 2013
Self-expandable stents are widely available for the treatment of perforation of the gastrointestinal tract. Because of the risk of migration, there has been no report of the use of self-expandable stents for the treatment of perforation of the colon or rectum. This is a report of successful treat..
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Pulmonology / Original Article
The diagnostic efficacy and safety of endobronchial ultrasound-guided transbronchial needle aspiration as an initial diagnostic tool
Young Rak Choi, Jin Young An, Mi Kyeong Kim, Hye-Suk Han, Ki Hyeong Lee, Si-Wook Kim, Ki Man Lee, Kang Hyeon Choe
Korean J Intern Med. 2013;28(6):660-667. Published online October 29, 2013
Background/Aims: Real-time, convex probe endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is used for the staging of malignant mediastinal lymph nodes. We evaluated the diagnostic efficacy and safety of EBUS-TBNA when used as an initial diagnostic tool. Methods: We retros..
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Microbiology / Review
Counteracting the enzymatic activity of dipeptidylpeptidase 4 for potential therapeutic advantage, with an emphasis on cord blood transplantation
Hal E. Broxmeyer
Korean J Intern Med. 2013;28(6):639-645. Published online October 29, 2013
Dipeptidylpeptidase (DPP) 4, also known as CD26, is an enzyme present on the surface of a number of different cell types. It is also found within cells and as a soluble protein in body fluids. It can specifically truncate proteins at the penultimate N-terminus residue for some amino acids, such a..
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Letter to the editor
Hemothorax caused by spontaneous rupture of a metastatic mediastinal lymph node in hepatocellular carcinoma: a case report
Ssang Yong Oh, Kwang Won Seo, Yangjin Jegal, Jong-Joon Ahn, Young Joo Min, Chang Ryul Park, Jae Cheol Hwang
Korean J Intern Med. 2013;28(5):622-625. Published online August 14, 2013
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Letter to the editor
Aortic intramural hematoma after thrombolysis in a patient with acute massive pulmonary embolism
Min Su Kim, Kyu Seop Kim, Il Soon Jung, Jae-Hyeong Park, Jin-Ok Jeong, Si Wan Choi, In-Whan Seong
Korean J Intern Med. 2013;28(5):619-621. Published online August 14, 2013
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Case Report
Reversible dilated cardiomyopathy caused by idiopathic hypoparathyroidism
Youn Joo Jung, Sung Eun Kim, Ji Yeon Hong, Jun Hee Lee, Dae Gyun Park, Kyoo Rok Han, Dong Jin Oh
Korean J Intern Med. 2013;28(5):605-608. Published online August 14, 2013
Dilated cardiomyopathy (DCM) is usually an idiopathic disease with a poor prognosis. Hypocalcemia is a rare and reversible cause of DCM. Here, we report a 50-year-old female with DCM, induced by idiopathic hypoparathyroidism, that improved after treatment with calcium.
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Case Report
Endoscopic ultrasound-guided fine needle aspiration of solid pseudopapillary tumors of the pancreas: a report of three cases
Hye Yon Park, Yoon Jung Lee, Jun Hee Lee, Min Ji Lee, Jong Kyun Lee, Kyu Taek Lee, Kwang Hyuck Lee
Korean J Intern Med. 2013;28(5):599-604. Published online August 14, 2013
The solid pseudopapillary tumor (SPT) of the pancreas is a rare but low-grade malignant tumor with a good prognosis after surgical excision. Endoscopic ultrasound (EUS)-guided fine needle aspiration (FNA) is a minimally invasive, safe and reliable way of diagnosing SPT by providing characteristic..
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Endocrinology-metabolism / Original Article
Neuroprotective effects of Vitis vinifera extract on prediabetic mice induced by a high-fat diet
Heung Yong Jin, Youn Soo Cha, Hong Sun Baek, Tae Sun Park
Korean J Intern Med. 2013;28(5):579-586. Published online August 14, 2013
Background/AimsVitis vinifera grape seed extract (VVE) contains oligomeric proanthocyanidins that show antioxidant and free radical-scavenging activities. We evaluated VVE for its neuroprotective effect in prediabetic mice induce by a high-fat diet (HD).
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Gastroenterology / Original Article
Expression of procaspase 3 and activated caspase 3 and its relevance in hormone-responsive gallbladder carcinoma chemotherapy
Sanjeev Kumar Maurya, Mallika Tewari, Bechan Sharma, Hari Shanker Shukla
Korean J Intern Med. 2013;28(5):573-578. Published online August 14, 2013
Background/AimsThe higher incidence of gallbladder cancer (GBC) in females has been accredited to the involvement of hormones. The clinical implications of sex hormone receptors in GBC are well established. Cysteine proteases (such as caspase-3-9, etc.) are known to play a cen..
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Gastroenterology / Review
Current status of chemotherapy for the treatment of advanced biliary tract cancer
Takashi Sasaki, Hiroyuki Isayama, Yousuke Nakai, Kazuhiko Koike
Korean J Intern Med. 2013;28(5):515-524. Published online August 14, 2013
Chemotherapy is indispensable for the treatment of advanced biliary tract cancer. Recently, reports regarding first-line chemotherapy have increased, and first-line chemotherapy treatment has become gradually more sophisticated. Gemcitabine and cisplatin combination therapy (or gemcitabine and ox..
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Case Report
Takayasu arteritis associated with ulcerative colitis and optic neuritis: first case in Korea
Jung Yoon Pyo, Jin Su Park, Chang Ho Song, Sang Won Lee, Yong Beom Park, Soo Kon Lee
Korean J Intern Med. 2013;28(4):491-496. Published online July 1, 2013
Takayasu arteritis (TA) is a chronic vasculitis that affects the aortic arch and its primary branches. Ulcerative colitis (UC) is an inflammatory bowel disease of unknown etiology. Patients diagnosed with both TA and UC have rarely been reported. The pathogenesis of TA and UC is uncertain, but ce..
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Pulmonology / Original Article
The start of chemotherapy until the end of radiotherapy in patients with limited-stage small cell lung cancer
Kyoung Ju Lee, Eun Joo Lee, Gyu Young Hur, Sang Yeub Lee, Je Hyeong Kim, Chol Shin, Jae Jeong Shim, Kwang Ho In, Kyung Ho Kang, Se Hwa Yoo, Sung Yong Lee
Korean J Intern Med. 2013;28(4):449-455. Published online July 1, 2013
Background/AimsChemotherapy combined with radiation therapy is the standard treatment for limited stage small cell lung cancer (LS-SCLC). Although numerous studies indicate that the overall duration of chemoradiotherapy is the most relevant predictor of outcome, the optimal ch..
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Nephrology / Original Article
The dose of cyclophosphamide for treating paraquat-induced rat lung injury
Jae-Sung Choi, Sung-Shick Jou, Mee-Hye Oh, Young-Hee Kim, Min-Ju Park, Hyo-Wook Gil, Ho-Yeon Song, Sae-Yong Hong
Korean J Intern Med. 2013;28(4):420-427. Published online July 1, 2013
Background/AimsCyclophosphamide (CP) is a promising treatment for severe cases of paraquat (PQ) poisoning. We investigated the effective dose of CP for mitigating PQ-induced lung injury. MethodsAdult male Sprague-Dawley rats were allocated into ..
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Hemato-oncology / Review
Clinical applications of mesenchymal stem cells
Nayoun Kim, Seok-Goo Cho
Korean J Intern Med. 2013;28(4):387-402. Published online July 1, 2013
Mesenchymal stem cells (MSCs) are self-renewing, multipotent progenitor cells with multilineage potential to differentiate into cell types of mesodermal origin, such as adipocytes, osteocytes, and chondrocytes. In addition, MSCs can migrate to sites of inflammation and exert potent immunosuppress..
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Letter to the editor
Spontaneous coronary artery dissection diagnosed by intravascular ultrasound and followed up by cardiac computed tomography
Sang-Woong Choi, Chang-Wook Nam, Han-Jun Bae, Yun-Kyeong Cho, Hyuck-Jun Yoon, Seung-Ho Hur, Kwon-Bae Kim
Korean J Intern Med. 2013;28(3):370-373. Published online May 1, 2013
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Case Report
A case of hemophagocytic syndrome in a patient with fulminant ulcerative colitis superinfected by cytomegalovirus
Jun Il Mun, Sung Jae Shin, Byung Hyun Yu, Jee Hoon Koo, Dong Hoon Kim, Ki Myoung Lee, Kwang Jae Lee
Korean J Intern Med. 2013;28(3):352-355. Published online May 1, 2013
Hemophagocytic syndrome (HPS) is an uncommon hematological disorder that manifests as fever, splenomegaly, and jaundice, with hemophagocytosis in the bone marrow and other tissues pathologically. Secondary HPS is associated with malignancy and infection, especially viral infection. The prevalence..
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Nephrology / Original Article
Clinical characteristics and outcomes in renal transplant recipients with renal cell carcinoma in the native kidney
In O Sun, Yu Mi Ko, Eun Young Kim, Kyung Seon Park, Hong Soon Jung, Sun Hye Ko, Byung Ha Chung, Bum Soon Choi, Cheol Whee Park, Yong Soo Kim, Chul Woo Yang
Korean J Intern Med. 2013;28(3):347-351. Published online May 1, 2013
Background/AimsWe investigated the incidence and clinical characteristics of renal cell carcinoma (RCC) in the native kidney of renal transplant recipients. MethodsBetween 1991 and 2010, 1,425 patients underwent kidney transplantation at our ins..
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Pulmonology / Original Article
Relationship between bronchial anthracofibrosis and endobronchial tuberculosis
Hyun Ji Kim, Sang Dong Kim, Dong Woo Shin, Soo Hyun Bae, Ah Lim Kim, Ji Na Kim, Seung Wook Jung, Byung Ki Lee, Yeon Jae Kim
Korean J Intern Med. 2013;28(3):330-338. Published online May 1, 2013
Background/AimsVarious pulmonary diseases may be associated with bronchial anthracofibrosis (BAF). Our aim was to identify a relationship between BAF and endobronchial tuberculosis (EBTB). MethodsIn total, 156 patients, diagnosed with EBTB using..
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