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Original Article
Role of 68Ga-DOTATOC PET/CT in the Evaluation of Primary Pulmonary Carcinoids
Tarun Jindal, Arvind Kumar, Balasubramanian Venkitaraman, Roman Dutta, Rakesh Kumar
Korean J Intern Med. 2010;25(4):386-391. Published online November 27, 2010
Background/AimsAlthough carcinoid tumors usually have good prognosis, early and specific diagnosis is important. Computed tomography and magnetic resonance imaging do not provide findings that are specific for carcinoids, and somatostatin receptor scintigraphy suffers from low..
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Original Article
Usual Dose of Simvastatin Does Not Inhibit Plaque Progression and Lumen Loss at the Peri-Stent Reference Segments after Bare-Metal Stent Implantation: A Serial Intravascular Ultrasound Analysis
Young Joon Hong, Myung Ho Jeong, Yun Ha Choi, Eun Hye Ma, Jum Suk Ko, Min Goo Lee, Keun Ho Park, Doo Sun Sim, Nam Sik Yoon, Hyun Ju Youn, Kye Hun Kim, Hyung Wook Park, Ju Han Kim, Youngkeun Ahn, Jeong Gwan Cho, Jong Chun Park, Jung Chaee Kang
Korean J Intern Med. 2010;25(4):356-363. Published online November 27, 2010
Background/AimsThe aim of this study was to assess the effects of a usual dose of simvastatin (20 mg/day) on plaque regression and vascular remodeling at the peri-stent reference segments after bare-metal stent implantation. MethodsWe retrospect..
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Review
The Role of Photodynamic Therapy for Hilar Cholangiocarcinoma
Young Koog Cheon
Korean J Intern Med. 2010;25(4):345-352. Published online November 27, 2010
The prognosis for hilar cholangiocarcinoma is limited by tumor spread along the biliary tree leading to refractory obstructive cholestasis, cholangitis, and liver failure. Palliation with biliary endoprostheses results in median survival times of 4-6 months for advanced bile duct cancer. Photodyn..
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Case Report
A Case of Type B Dissecting Aneurysm Involving Right Sided Aorta with Kommerell's Diverticulum
So Yeon Kim, Young Soo Lee, Kyung Ryun Bae, Jin Bae Lee, Sub Lee, Oh Choon Kwon
Korean J Intern Med. 2010;25(3):327-330. Published online August 31, 2010
A right-sided aortic arch (RAA) is a rare congenital anomaly, and Stanford type B dissection aneurysms involving this anomaly is also uncommon. Surgical approaches to dealing with an RAA are complicated by the unusual anatomical features of the condition. Here we report the case of a 47-year-old ..
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Original Article
Induction of Macrophage Migration Inhibitory Factor in ConA-Stimulated Rheumatoid Arthritis Synovial Fibroblasts through the P38 MAP Kinase-Dependent Signaling Pathway
Hae-Rim Kim, Mi-Kyung Park, Mi-La Cho, Kyoung-Woon Kim, Hye-Joa Oh, Jin-Sil Park, Yang-Mi Heo, Sang-Heon Lee, Ho-Youn Kim, Sung-Hwan Park
Korean J Intern Med. 2010;25(3):317-326. Published online August 31, 2010
Background/AimsThis study was undertaken to identify the intracellular signaling pathway involved in induction of macrophage migration inhibitory factor (MIF) in human rheumatoid arthritis (RA) synovial fibroblasts. MethodsHuman RA synovial fibr..
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Original Article
Modified Number of Extranodal Involved Sites as a Prognosticator in R-CHOP-Treated Patients with Disseminated Diffuse Large B-Cell Lymphoma
Changhoon Yoo, Shin Kim, Byeong Seok Sohn, Jeong-Eun Kim, Dok Hyun Yoon, Jooryung Huh, Dae Ho Lee, Sang-We Kim, Jung-Shin Lee, Cheolwon Suh
Korean J Intern Med. 2010;25(3):301-308. Published online August 31, 2010
Background/AimsRituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone chemotherapy (R-CHOP) has improved survival in patients with diffuse large B-cell lymphoma (DLBCL) and weakened the prognostic power of the international prognostic index (IPI). We evaluat..
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Original Article
Changing Donor Source Pattern for Kidney Transplantation over 40 Years: A Single-Center Experience
Byung Ha Chung, Mi Hyang Jung, Sung Ha Bae, Suk Hui Kang, Hyeon Seok Hwang, Bok Jin Hyoung, So Young Lee, Youn Ju Jeon, Bum Soon Choi, Cheol Whee Park, Yong-Soo Kim, Ji-Il Kim, In Sung Moon, Chul Woo Yang
Korean J Intern Med. 2010;25(3):288-293. Published online August 31, 2010
Background/AimsKidney transplantations at our center rely mainly on living donors. The purpose of this study was to suggest future donor supply directions by reviewing changing trends in donor type. MethodsDuring the past 40 years, 1,690 kidney ..
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Original Article
Effect of Glutathione Administration on Serum Levels of Reactive Oxygen Metabolites in Patients with Paraquat Intoxication: A Pilot Study
Jung-Hoon Kim, Hyo-Wook Gil, Jong-Oh Yang, Eun-Young Lee, Sae-Yong Hong
Korean J Intern Med. 2010;25(3):282-287. Published online August 31, 2010
Background/AimsBased on preliminary in vitro data from a previous study, we proposed that 50 mg/kg glutathione (GSH) would be adequate for suppressing reactive oxygen species in patients with acute paraquat (PQ) intoxication. Methods
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Original Article
Usefulness of Peak Systolic Strain Measurement by Automated Function Imaging in the Prediction of Coronary Perfusion in Patients with Acute Myocardial Infarction
Jung Sun Cho, Kye Hun Kim, Woo Seok Lee, Hyun Ju Yoon, Nam Sik Yoon, Young Joon Hong, Hyung Wook Park, Ju Han Kim, Youngkeun Ahn, Myung Ho Jeong, Jeong Gwan Cho, Jong Chun Park, Jung Chaee Kang
Korean J Intern Med. 2010;25(3):260-268. Published online August 31, 2010
Background/AimsThe usefulness of global longitudinal peak systolic strain (GLPSS) measurement by automated function imaging (AFI) in the prediction of perfusion status of infarct-related artery (IRA) before percutaneous coronary intervention (PCI) was evaluated.
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Original Article
Left Ventricular Dyssynchrony in Patients Showing Diastolic Dysfunction without Overt Symptoms of Heart Failure
Jae Hoon Kim, Hee Sang Jang, Byung Seok Bae, Seung Min Shin, Ki Ju Kim, Jung Gil Park, Hyun Jae Kang, Bong Ryeol Lee, Byung Chun Jung
Korean J Intern Med. 2010;25(3):246-252. Published online August 31, 2010
Background/AimsFew studies have assessed left ventricular (LV) dyssynchrony in cases of diastolic dysfunction that do not include overt symptoms of heart failure. We hypothesized that systolic or diastolic dyssynchrony involves unique features with respect to the degree of dia..
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Original Article
Variable Association between Components of the Metabolic Syndrome and Electrocardiographic Abnormalities in Korean Adults
Hong-Kyu Kim, Chul-Hee Kim, Kwan-Ho Ko, Seong-Wook Park, Joong-Yeol Park, Ki-Up Lee
Korean J Intern Med. 2010;25(2):174-180. Published online June 1, 2010
Background/AimsResting electrocardiogram (ECG) abnormalities have been strongly associated with cardiovascular disease mortality. Little is known, however, about the association between individual components of metabolic syndrome and ECG abnormalities, especially in Asian popu..
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Original Article
Diet and Airway Obstruction: A Cross Sectional Study from the Second Korean National Health and Nutrition Examination Survey
Jin Hwa Lee, Yun Su Sim, Gee Young Suh, Jeong-Seon Ryu, Dong Ho Shin, Kyung Haeng Koh, Yeon Jae Kim, Wan Park, Hyoung Kyu Yoon, Man Jae Lee, Jung Hyun Chang,
Korean J Intern Med. 2010;25(2):132-139. Published online June 1, 2010
Background/AimsSeveral dietary factors, such as antioxidant vitamins, have potential roles in the development of obstructive lung diseases. However, the results of studies on the relationships between dietary factors and obstructive lung diseases are inconsistent. The aim of t..
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Review
Molecular Mechanism of Insulin Resistance in Obesity and Type 2 Diabetes
Kangduk Choi, Young-Bum Kim
Korean J Intern Med. 2010;25(2):119-129. Published online June 1, 2010
Insulin resistance is a major risk factor for developing type 2 diabetes caused by the inability of insulin-target tissues to respond properly to insulin, and contributes to the morbidity of obesity. Insulin action involves a series of signaling cascades initiated by insulin binding to its recept..
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Case Report
A Case Report of the Second de Novo Acute Myeloid Leukemia (AML) Following Allogeneic Stem Cell Transplantation in a Patient with the First AML
Byung-Sik Cho, Hee-Je Kim, Ki-Sung Eom, Jong-Wook Lee, Woo-Sung Min, Chun-Choo Kim
Korean J Intern Med. 2010;25(1):110-113. Published online February 26, 2010
Secondary leukemia occurring after hematopoietic stem cell transplantation (HSCT) for acute myeloid leukemia (AML) is rare. Secondary AML usually follows autologous and not allogeneic transplants. When a new leukemia develops in a patient successfully treated with an allogeneic HSCT, the possibil..
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Case Report
Myasthenia Gravis Presenting as Isolated Respiratory Failure: A Case Report
Won Hee Kim, Jung Hyun Kim, Eun Kyung Kim, Sang Pil Yun, Kyung Keun Kim, Won Chan Kim, Hye Cheol Jeong
Korean J Intern Med. 2010;25(1):101-104. Published online February 26, 2010
Myasthenia gravis (MG) is often complicated by respiratory failure, known as a myasthenic crisis. However, most of the patients who develop respiratory symptoms do so during the late course of disease and have other neurological signs and symptoms. However, in some patients respiratory failure is..
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Original Article
Ethyl Acetate Fraction from Cudrania Tricuspidata Inhibits IL-1β-Stimulated Osteoclast Differentiation through Downregulation of MAPKs, c-Fos and NFATc1
Eun-Gyeong Lee, Hee-Jin Yun, Sang-Il Lee, Wan-Hee Yoo
Korean J Intern Med. 2010;25(1):93-100. Published online February 26, 2010
Background/AimsThe present study was performed to determine the effects of the ethyl acetate extract of Cudrania tricuspidata (EACT) on interleukin (IL)-1β-stimulated receptor activator of NF-κB ligand (RANKL)-mediated osteoclast differentiation.
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Original Article
Severe Pulmonary Adverse Effects in Lymphoma Patients Treated with Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (CHOP) Regimen Plus Rituximab
Kyu-Hyoung Lim, Ho-Il Yoon, Young Ae Kang, Keun-Wook Lee, Jee Hyun Kim, Soo-Mee Bang, Jae Ho Lee, Choon-Taek Lee, Jong Seok Lee
Korean J Intern Med. 2010;25(1):86-92. Published online February 26, 2010
Background/AimsThe aim of our study was to determine the incidence and clinical features of severe pulmonary complications in patients receiving cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) or rituximab plus CHOP (R-CHOP) as the initial treatment for lymph..
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Original Article
Ultrasonographic Features of Papillary Thyroid Carcinoma in Patients with Graves' Disease
Jin Ook Chung, Dong Hyeok Cho, Dong Jin Chung, Min Young Chung
Korean J Intern Med. 2010;25(1):71-76. Published online February 26, 2010
Background/AimsTo characterize ultrasonographic findings in papillary thyroid carcinoma (PTC) combined with Graves' disease. MethodsMedical records and ultrasonographic findings of 1,013 patients with Graves' disease and 3,380 patients without G..
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Original Article
Clinical Characteristics of Pulmonary Embolism with Underlying Malignancy
Ji Eun Lee, Hye-Ryoun Kim, Sang-Min Lee, Jae-Joon Yim, Chul-Gyu Yoo, Young Whan Kim, Sung Koo Han, Young-Soo Shim, Seok-Chul Yang
Korean J Intern Med. 2010;25(1):66-70. Published online February 26, 2010
Background/AimsThe risk of venous thromboembolism (VTE), which encompasses deep vein thrombosis and pulmonary embolism (PE), increases in patients with cancer. Anticancer treatment is also associated with an increased risk for VTE. We conducted this study to investigate the cl..
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Original Article
Clinical Meaning of Early Oxygenation Improvement in Severe Acute Respiratory Distress Syndrome under Prolonged Prone Positioning
Kwangha Lee, Mi-Young Kim, Jung-Wan Yoo, Sang-Bum Hong, Chae-Man Lim, Younsuck Koh
Korean J Intern Med. 2010;25(1):58-65. Published online February 26, 2010
Background/AimsVentilating patients with acute respiratory distress syndrome (ARDS) in the prone position has been shown to improve arterial oxygenation, but prolonged prone positioning frequently requires continuous deep sedation, which may be harmful to patients. We evaluated..
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