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Rheumatology / Original Article
Predictive factors of radiographic progression in ankylosing spondylitis
Hyungjin Kim, Jaejoon Lee, Joong Kyong Ahn, Jiwon Hwang, Eun-Jung Park, Hyemin Jeong, Hoon-Suk Cha, Eun-Mi Koh
Korean J Intern Med. 2015;30(3):391-397. Published online April 29, 2015
Background/Aims: The course of ankylosing spondylitis (AS) is rather variable, and the factors that predict radiographic progression remain largely obscure. In this study, we tried to determine the clinical factors and laboratory measures that are useful in predicting the radiographic progression of..
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Nephrology / Original Article
Plasma neutrophil gelatinase-associated lipocalin as a potential predictor of adverse renal outcomes in immunoglobulin A nephropathy
Ga-Young Park, Chung-Hoon Yu, Jun-Seop Kim, Yun-Jeong Kang, Owen Kwon, Ji-Young Choi, Jang-Hee Cho, Chan-Duck Kim, Yong-Lim Kim, Sun-Hee Park
Korean J Intern Med. 2015;30(3):345-353. Published online April 29, 2015
Background/Aims: Neutrophil gelatinase-associated lipocalin (NGAL) is a well-known biomarker of acute kidney injury. We evaluated the value of plasma NGAL (pNGAL) as an independent predictor of prognosis in immunoglobulin A nephropathy (IgAN).
Methods: In total, 91 patients with biopsy-proven IgAN ..
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Gastroenterology / Original Article
Long-term outcomes of balloon dilation versus botulinum toxin injection in patients with primary achalasia
Ho Eun Jung, Joon Seong Lee, Tae Hee Lee, Jin Nyoung Kim, Su Jin Hong, Jin Oh Kim, Hyeon Geon Kim, Seong Ran Jeon, Joo Young Cho
Korean J Intern Med. 2014;29(6):738-745. Published online October 31, 2014
Background/Aims: We compared the long-term outcomes of balloon dilation versus botulinum toxin injection in Korean patients with primary achalasia and identified factors predicting remission.
Methods: We included 73 patients with achalasia newly diagnosed between January 1988 and January 2011. We u..
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Endocrinology-metabolism / Original Article
The effect of high-dose vitamin D supplementation on insulin resistance and arterial stiffness in patients with type 2 diabetes
Ohk-Hyun Ryu, Wankyo Chung, Sungwha Lee, Kyung-Soon Hong, Moon-Gi Choi, Hyung Joon Yoo
Korean J Intern Med. 2014;29(5):620-629. Published online August 28, 2014
Background/Aims: Recent epidemiological studies revealed a striking inverse relationship between vitamin D levels, glucose intolerance/insulin resistance (IR), and cardiovascular disease. However, few interventional studies have evaluated the effect of vitamin D supplementation on cardiovascular ris..
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Nephrology / Original Article
Ferritin as a predictor of decline in residual renal function in peritoneal dialysis patients
Soon Mi Hur, Hye Young Ju, Moo Yong Park, Soo Jeong Choi, Jin Kuk Kim, Seung Duk Hwang
Korean J Intern Med. 2014;29(4):489-497. Published online June 27, 2014
Background/Aims: Inflammation is an important factor in renal injury. Ferritin, an inflammatory marker, is considered an independent predictor of rapid renal progression in patients with chronic kidney disease. However, the relationship between ferritin and residual renal function (RRF) in patients ..
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Nephrology / Review
Vitamin D and chronic kidney disease
Chang Seong Kim, Soo Wan Kim
Korean J Intern Med. 2014;29(4):416-427. Published online June 27, 2014
Chronic kidney disease (CKD) has been recognized as a significant global health problem because of the increased risk of total and cardiovascular morbidity and mortality. Vitamin D deficiency or insufficiency is common in patients with CKD, and serum levels of vitamin D appear to have an inverse cor..
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Nephrology / Original Article
A mild decrease of renal function is related to increased hemoglobin level during 5-year follow-up period
Nara Shin, Hyunsuk Kim, Hyo Jin Kim, Miyeun Han, Sunhwa Lee, Hyungah Jo, Huh Hyuk, Ho Jun Chin
Korean J Intern Med. 2014;29(3):341-351. Published online April 29, 2014
Background/Aims: We analyzed chronological changes in hemoglobin according to renal function changes over a 5-year follow-up period.
Methods: We enrolled 5,266 adults with a glomerular filtration rate (GFR) ≥ 60 mL/min/1.73 m2 at an initial examination at a routine heal..
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Case Report
Ifosfamide-induced Fanconi syndrome with diabetes insipidus
Ah Young Leem, Han Sang Kim, Byung Woo Yoo, Beo Deul Kang, Min Hwan Kim, Sun Young Rha, Hyo Song Kim
Korean J Intern Med. 2014;29(2):246-249. Published online February 27, 2014
Ifosfamide-induced Fanconi syndrome is a rare complication that typically occurs in young patients due to a cumulative dose of ifosfamide > 40–60 g/m2, a reduction in kidney mass, or concurrent cisplatin treatment. It is usually characterized by severe and fatal progression accompanied by type II ..
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Endocrinology-metabolism / Original Article
Measurement of antioxidant capacity using the biological antioxidant potential test and its role as a predictive marker of metabolic syndrome
Jung Hee Kim, Hyun Wook Baik, Yeong Sook Yoon, Hyo Jee Joung, Ju Sang Park, Sang Jong Park, Eun Jeong Jang, Sang Woon Park, Sang Jung Kim, Mi Jeoung Kim, Dong Ok Jeon, Hyo Jin Cho, Sang Jin Lee, Sung Gyu Im, Sun Kyung Jang
Korean J Intern Med. 2014;29(1):31-39. Published online January 2, 2014
Background/Aims: Oxidative stress increases the risk of cardiovascular complications
of metabolic syndrome (MetS). This study was conducted to examine the
difference in antioxidant capacity according to the presence of MetS, and to characterize
the association between antioxidant capacity and Me..
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Acute respiratory failure caused by phenytoin overdose
Chang Kyung Kang, Min-Kyung Kim, Min Jae Kim, Kang Il Jun, Ki Woong Kim, Seong-Ho Park, Kyoung-Ho Song
Korean J Intern Med. 2013;28(6):736-738. Published online October 29, 2013
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Letter to the editor
Acute regional myocarditis with normal ventricular wall motion diagnosed by two-dimensional speckle tracking imaging
Sang Jin Ha, Jong Shin Woo, Se Hwan Kwon, Chi Hyuk Oh, Kwon Sam Kim, Jong-Hoa Bae, Woo-Shik Kim
Korean J Intern Med. 2013;28(6):732-735. Published online October 29, 2013
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Case Report
Gestational hyperlipidemia and acute pancreatitis with underlying partial lipoprotein lipase deficiency and apolipoprotein E3/E2 genotype
Dong Hee Han, In Ho Moh, Doo-Man Kim, Sung Hee Ihm, Moon-Gi Choi, Hyung Joon Yoo, Eun-Gyoung Hong
Korean J Intern Med. 2013;28(5):609-613. Published online August 14, 2013
We report the case of a patient who experienced extreme recurrent gestational hyperlipidemia. She was diagnosed with partial lipoprotein lipase (LPL) deficiency but without an associated LPL gene mutation in the presence of the apolipoprotein E3/2 genotype. This is the first reported case of extr..
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Endocrinology-metabolism / Original Article
Adipokines, insulin-like growth factor binding protein-3 levels, and insulin sensitivity in women with polycystic ovary syndrome
Hyejin Lee, Jee-Young Oh, Yeon-Ah Sung
Korean J Intern Med. 2013;28(4):456-463. Published online July 1, 2013
Background/AimsMany women with polycystic ovary syndrome (PCOS) exhibit insulin resistance. Adipose tissue plays an important role in insulin resistance, and adipokines including tumor necrosis factor (TNF)-α and adiponectin are altered in PCOS. Insulin-like growth factor bin..
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Gastroenterology / Original Article
Effects of D-002, a mixture of high molecular weight beeswax alcohols, on patients with nonalcoholic fatty liver disease
José Illnait, Iván Rodríguez, Sarahí Mendoza, Yolanda Fernández, Rosa Mas, Mirtha Miranda, Jesús Piñera, Julio César Fernández, Meilis Mesa, Lilia Fernández, Daisy Carbajal, Rafael Gámez
Korean J Intern Med. 2013;28(4):439-448. Published online July 1, 2013
Background/AimsNonalcoholic fatty liver disease (NAFLD) is intimately related to insulin resistance and ranges from a benign course to liver fibrosis and cirrhosis. NAFLD management mainly involves dietary modification and weight loss. Although no fully successful pharmacologi..
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Letter to the editor
The renoprotective effects of pentoxifylline: beyond its role in diabetic nephropathy
Shailendra Kapoor
Korean J Intern Med. 2013;28(3):374-376. Published online May 1, 2013
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Endocrinology-metabolism / Original Article
Low glibenclamide concentrations affect endoplasmic reticulum stress in INS-1 cells under glucotoxic or glucolipotoxic conditions
Min Jeong Kwon, Hye Suk Chung, Chang Shin Yoon, Eun Ju Lee, Tae Kyun Kim, Soon Hee Lee, Kyung Soo Ko, Byoung Doo Rhee, Mi Kyung Kim, Jeong Hyun Park
Korean J Intern Med. 2013;28(3):339-346. Published online May 1, 2013
Background/Aimsβ-Cell apoptosis caused by increased endoplasmic reticulum (ER) stress is an important pathogenic component of type 2 diabetes mellitus. In theory, sulfonylureas, used for the treatment of diabetes, can contribute to ER stress. We assessed changes in ER stress ..
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Endocrinology-metabolism / Original Article
Insulin secretion and insulin resistance in Korean women with gestational diabetes mellitus and impaired glucose tolerance
Sae Jeong Yang, Tae Nyun Kim, Sei Hyun Baik, Tae Sun Kim, Kwan Woo Lee, Moonsuk Nam, Yong Soo Park, Jeong-Teak Woo, Young Seol Kim, Sung-Hoon Kim
Korean J Intern Med. 2013;28(3):306-313. Published online May 1, 2013
Background/AimsThe aim was to compare the insulin sensitivity and secretion index of pregnant Korean women with normal glucose tolerance (NGT), gestational impaired glucose tolerance (GIGT; only one abnormal value according to the Carpenter and Coustan criteria), and gestation..
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Letter to the editor
A case of membranoproliferative glomerulonephritis associated with metastatic colon cancer
Jung-Hwa Ryu, Soon Sup Chung, Dong-Ryeol Ryu, Seung-Jung Kim, Duk-Hee Kang, Sun Hee Sung, Kyu-Bok Choi
Korean J Intern Med. 2013;28(2):254-257. Published online February 27, 2013
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Rheumatology / Original Article
Is the frequency of metabolic syndrome higher in South Korean women with rheumatoid arthritis than in healthy subjects?
Seung-Geun Lee, Ji-Min Kim, Sun-Hee Lee, Kye-Hyung Kim, Ji-Hye Kim, Ji-Won Yi, Woo-Jin Jung, Young-Eun Park, Seong-Hu Park, Joung-Wook Lee, Seung-Hoon Baek, Jun-Hee Lee, Geun-Tae Kim
Korean J Intern Med. 2013;28(2):206-215. Published online February 27, 2013
Background/AimsTo compare the frequency of metabolic syndrome (MetS) and magnitude of insulin resistance, measured by the homeostatic model assessment of insulin resistance (HOMA-IR), between South Korean women with rheumatoid arthritis (RA) and healthy subjects, and to evalua..
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Letter to the editor
Zotarolimus-eluting stent-induced hypersensitivity pneumonitis
Hong-Won Shin, Chang-Wook Nam, Hyungseop Kim, Seung-Ho Hur, Yoon-Nyun Kim, Kwon-Bae Kim, Kun-Young Kwon
Korean J Intern Med. 2013;28(1):108-111. Published online December 28, 2012
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