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Original Article
Comparison of Drug-Eluting Stents in Acute Myocardial Infarction Patients with Chronic Kidney Disease
Daisuke Hachinohe, Myung Ho Jeong, Shigeru Saito, Min Chol Kim, Kyung Hoon Cho, Khurshid Ahmed, Seung Hwan Hwang, Min Goo Lee, Doo Sun Sim, Keun-Ho Park, Ju Han Kim, Young Joon Hong, Youngkeun Ahn, Jung Chaee Kang, Jong Hyun Kim, Shung Chull Chae, Young Jo Kim, Seung Ho Hur, In Whan Seong, Taek Jong Hong, Donghoon Choi, Myeong Chan Cho, Chong Jin Kim, Ki Bae Seung, Wook Sung Chung, Yang Soo Jang, Seung Woon Rha, Jang Ho Bae, Seung Jung Park,
Korean J Intern Med. 2012;27(4):397-406. Published online November 27, 2012
Background/AimsTo determine which drug-eluting stents are more effective in acute myocardial infarction (MI) patients with chronic kidney disease (CKD). MethodsThis study included a total of 3,566 acute MI survivors with CKD from the Korea Acute..
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Original Article
Characteristics of Subjects with Very Low Serum Low-Density Lipoprotein Cholesterol and the Risk for Intracerebral Hemorrhage
Jae-Geun Lee, Sung Joo Koh, So Yeon Yoo, Jung Re Yu, Sang Ah Lee, Gwanpyo Koh, Daeho Lee
Korean J Intern Med. 2012;27(3):317-326. Published online September 1, 2012
Background/AimsThe clinical implications of hypocholesterolemia have not been well studied, although some studies have revealed an association between hypocholesterolemia and intracerebral hemorrhage (ICH). We evaluated the clinical characteristics of subjects with very low-de..
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Original Article
Associations between Hemoglobin Concentrations and the Clinical Characteristics of Patients with Type 2 Diabetes
Jin Ook Chung, Dong Hyeok Cho, Dong Jin Chung, Min Young Chung
Korean J Intern Med. 2012;27(3):285-292. Published online September 1, 2012
Background/AimsMany studies have demonstrated an association between hemoglobin levels and cardiovascular disease in diabetic patients. The aim of this study was to determine whether there is an association between hemoglobin concentrations and various clinical parameters, inc..
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Review
Echocardiography in Transcatheter Aortic Valve Implantation and Mitral Valve Clip
Robert J. Siegel, Huai Luo
Korean J Intern Med. 2012;27(3):245-261. Published online September 1, 2012
Transcatheter aortic valve implantation and transcatheter mitral valve repair (MitraClip) procedures have been performed worldwide. In this paper, we review the use of two-dimensional and three-dimensional transesophageal echo for guiding transcatheter aortic valve replacement and mitral valve re..
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Original Article
Associations among Body Mass Index, Insulin Resistance, and Pancreatic β-Cell Function in Korean Patients with New-Onset Type 2 Diabetes
Jin Ook Chung, Dong Hyeok Cho, Dong Jin Chung, Min Young Chung
Korean J Intern Med. 2012;27(1):66-71. Published online February 28, 2012
Background/AimsWe investigated the associations among body mass index (BMI), insulin resistance, and β-cell function in Korean patients newly presenting with type 2 diabetes. MethodsIn total, 132 patients with new-onset type 2 diabetes mellitu..
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Review
Albumin for End-Stage Liver Disease
June Sung Lee
Korean J Intern Med. 2012;27(1):13-19. Published online February 28, 2012
Albumin has been widely used in patients with cirrhosis in an attempt to improve circulatory and renal functions. The benefits of albumin infusions in preventing the deterioration in renal function associated with large-volume paracentesis, spontaneous bacterial peritonitis, and established hepat..
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Letter to the editor
Two Cases of Scrub Typhus Presenting with Guillain-Barré Syndrome with Respiratory Failure
Il Nam Ju, Jung Woo Lee, Sung Yeoun Cho, Seung Jee Ryu, Youn Jeong Kim, Sang Il Kim, Moon Won Kang
Korean J Intern Med. 2011;26(4):474-476. Published online November 28, 2011
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Case Report
Central Venous Stenosis Caused by Traction of the Innominate Vein due to a Tuberculosis-Destroyed Lung
Eun Ju Song, Dae Hyun Baek, Young-Hwan Hwang, So-Young Lee, Young-Kwon Cho, Su-Ah Sung
Korean J Intern Med. 2011;26(4):460-462. Published online November 28, 2011
We report a case of central venous stenosis due to a structural deformity caused by a tuberculosis-destroyed lung in a 65-year-old woman. The patient presented with left facial edema. She had a history of pulmonary tuberculosis, and the chest X-ray revealed a collapsed left lung. Angiography show..
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Original Article
Cyclosporin A Inhibits Albumin Synthesis in Huh7 Cells
Youn Joo Jeon, Yong Soo Kim
Korean J Intern Med. 2011;26(3):314-319. Published online September 13, 2011
Background/AimsHypoalbuminemia occurs frequently in renal transplant recipients immediately after renal transplantation. We studied the regulation of hepatic albumin synthesis by cyclosporin A (CsA) in Huh7 cells. MethodsHuh7 cells were incubate..
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Original Article
Nuclear factor E2-related factor 2 Dependent Overexpression of Sulfiredoxin and Peroxiredoxin III in Human Lung Cancer
Young Sun Kim, Hye Lim Lee, Ki Bum Lee, Joo Hun Park, Wou Young Chung, Keu Sung Lee, Seung Soo Sheen, Kwang Joo Park, Sung Chul Hwang
Korean J Intern Med. 2011;26(3):304-313. Published online September 13, 2011
Background/AimsOxidative stress results in protein oxidation and is implicated in carcinogenesis. Sulfiredoxin (Srx) is responsible for the enzymatic reversal of inactivated peroxiredoxin (Prx). Nuclear factor E2-related factor 2 (Nrf2) binds to antioxidant responsive elements..
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Original Article
Insulin Resistance as a Risk Factor for Gallbladder Stone Formation in Korean Postmenopausal Women
Sang Soo Kim, Jeong Gyu Lee, Dong Wok Kim, Bo Hyun Kim, Yun Kyung Jeon, Mi Ra Kim, Jeong Eun Huh, Ji Young Mok, Seong-Jang Kim, Yong Ki Kim, In Joo Kim
Korean J Intern Med. 2011;26(3):285-293. Published online September 13, 2011
Background/AimsThe objective of this study was to determine whether insulin resistance is associated with gallbladder stone formation in Korean women based on menopausal status. MethodsThe study included 4,125 consecutive Korean subjects (30-79 ..
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Original Article
Diagnostic Value of a Chimeric TSH Receptor (Mc4)-Based Bioassay for Graves' Disease
Ji In Lee, Hye Won Jang, Soo Kyoung Kim, Joon Young Choi, Ji Young Kim, Kyu Yeon Hur, Jae Hyeon Kim, Yong-Ki Min, Jae Hoon Chung, Sun Wook Kim
Korean J Intern Med. 2011;26(2):179-186. Published online June 1, 2011
Background/AimsGraves' disease (GD) is caused by thyroid-stimulating hormone receptor (TSHR) and thyroid-stimulating immunoglobulin (TSI). We used a recently introduced, technically enhanced TSI bioassay to assess its diagnostic value and determine the cut-off in patients in h..
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Original Article
Effects of the Transition from Premenopause to Postmenopause on Lipids and Lipoproteins: Quantification and Related Parameters
Eun Jeung Cho, Yun Joo Min, Min Seok Oh, Jee Eun Kwon, Jeung Eun Kim, Wang-Soo Lee, Kwang Je Lee, Sang-Wook Kim, Tae Ho Kim, Myung-A Kim, Chee Jeong Kim, Wang Seong Ryu
Korean J Intern Med. 2011;26(1):47-53. Published online March 2, 2011
Background/AimsThe aim of this study was to quantitatively measure changes in lipids and lipoproteins during perimenopause and to identify variables related to these changes. MethodsAmong women who had three regular health evaluations over a spa..
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Review
Prostaglandin D2 and TH2 Inflammation in the Pathogenesis of Bronchial Asthma
Masafumi Arima, Takeshi Fukuda
Korean J Intern Med. 2011;26(1):8-18. Published online March 2, 2011
Prostaglandin D2 (PGD2) is a major prostanoid, produced mainly by mast cells, in allergic diseases, including bronchial asthma. PGD2-induced vasodilatation and increased permeability are well-known classical effects that may be involved in allergic inflammation. R..
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Original Article
The Effect of Early Insulin Therapy on Pancreatic β-Cell Function and Long-Term Glycemic Control in Newly Diagnosed Type 2 Diabetic Patients
Suk Chon, Seungjoon Oh, Sung Woon Kim, Jin-Woo Kim, Young Seol Kim, Jeong-taek Woo
Korean J Intern Med. 2010;25(3):273-281. Published online August 31, 2010
Background/AimsBased on the results of well designed clinical studies, intensive insulin therapy has been established to improve glycemic control in newly diagnosed diabetes. However, discrepancies exist between the findings of clinical trials and experiences in general pract..
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Original Article
Diet and Airway Obstruction: A Cross Sectional Study from the Second Korean National Health and Nutrition Examination Survey
Jin Hwa Lee, Yun Su Sim, Gee Young Suh, Jeong-Seon Ryu, Dong Ho Shin, Kyung Haeng Koh, Yeon Jae Kim, Wan Park, Hyoung Kyu Yoon, Man Jae Lee, Jung Hyun Chang,
Korean J Intern Med. 2010;25(2):132-139. Published online June 1, 2010
Background/AimsSeveral dietary factors, such as antioxidant vitamins, have potential roles in the development of obstructive lung diseases. However, the results of studies on the relationships between dietary factors and obstructive lung diseases are inconsistent. The aim of t..
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Review
Molecular Mechanism of Insulin Resistance in Obesity and Type 2 Diabetes
Kangduk Choi, Young-Bum Kim
Korean J Intern Med. 2010;25(2):119-129. Published online June 1, 2010
Insulin resistance is a major risk factor for developing type 2 diabetes caused by the inability of insulin-target tissues to respond properly to insulin, and contributes to the morbidity of obesity. Insulin action involves a series of signaling cascades initiated by insulin binding to its recept..
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Case Report
Myasthenia Gravis Presenting as Isolated Respiratory Failure: A Case Report
Won Hee Kim, Jung Hyun Kim, Eun Kyung Kim, Sang Pil Yun, Kyung Keun Kim, Won Chan Kim, Hye Cheol Jeong
Korean J Intern Med. 2010;25(1):101-104. Published online February 26, 2010
Myasthenia gravis (MG) is often complicated by respiratory failure, known as a myasthenic crisis. However, most of the patients who develop respiratory symptoms do so during the late course of disease and have other neurological signs and symptoms. However, in some patients respiratory failure is..
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Original Article
Clinical Value of Serum Uric Acid in Patients with Suspected Coronary Artery Disease
Hong Euy Lim, Seong Hwan Kim, Eung Ju Kim, Jin Won Kim, Seung Woon Rha, Hong Seog Seo, Chang Gyu Park
Korean J Intern Med. 2010;25(1):21-26. Published online February 26, 2010
Background/AimsAlthough increased serum uric acid (SUA) concentrations are commonly encountered in patients with risk factors for coronary artery disease (CAD), the clinical value of SUA has not been established. MethodsThe study group comprised..
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Original Article
Long-Term Effects of Rosiglitazone on the Progressive Decline in Renal Function in Patients With Type 2 Diabetes
Mee Kyoung Kim, Seung-Hyun Ko, Ki-Hyun Baek, Yu-Bae Ahn, Kun-Ho Yoon, Moo-Il Kang, Kwang-Woo Lee, Ki-Ho Song
Korean J Intern Med. 2009;24(3):227-232. Published online August 26, 2009
Background/AimsThiazolidinediones reduce urinary albumin excretion and may prevent the development of renal injury. We evaluated the long-term effects of rosiglitazone on the progression of renal dysfunction in patients with type 2 diabetes mellitus. Metho..
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