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Nephrology / Original Article
A mild decrease of renal function is related to increased hemoglobin level during 5-year follow-up period
Nara Shin, Hyunsuk Kim, Hyo Jin Kim, Miyeun Han, Sunhwa Lee, Hyungah Jo, Huh Hyuk, Ho Jun Chin
Korean J Intern Med. 2014;29(3):341-351. Published online April 29, 2014
Background/Aims: We analyzed chronological changes in hemoglobin according to renal function changes over a 5-year follow-up period.
Methods: We enrolled 5,266 adults with a glomerular filtration rate (GFR) ≥ 60 mL/min/1.73 m2 at an initial examination at a routine heal..
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Nephrology / Review
The renin-angiotensin system and aging in the kidney
Hye Eun Yoon, Bum Soon Choi
Korean J Intern Med. 2014;29(3):291-295. Published online April 29, 2014
Aging is associated with progressive functional deterioration and structural changes in the kidney. Changes in the activity or responsiveness of the renin-angiotensin system (RAS) occur with aging. RAS changes predispose the elderly to various fluid and electrolyte imbalances as well as acute kidney..
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Cardiology / Original Article
Effect of renin-angiotensin-system blockers on contrast-medium-induced acute kidney injury after coronary angiography
Ja-Jun Goo, Jae-Joon Kim, Ji-Hoon Kang, Kyoung-Nyoun Kim, Ki-Sup Byun, Mi-kyung Kim, Tae-Ik Kim
Korean J Intern Med. 2014;29(2):203-209. Published online February 27, 2014
Background/Aims: With the increasing incidence of cardiovascular disease, angiocardiography using contrast-enhancing media has become an essential diagnostic and therapeutic tool, despite the risk of contrast-medium-induced acute kidney injury (CIAKI). CIAKI may be exacerbated by renin-angiotensin-s..
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Case Report
Hypothermia-induced acute kidney injury in an
elderly patient
Hyun Ju Yoon, Mun Chul Kim, Jae Woo Park, Min A Yang, Cheon Beom Lee, In O Sun, Kwang Young Lee
Korean J Intern Med. 2014;29(1):111-115. Published online January 2, 2014
Hypothermia, defined as an unintentional decline in the core body temperature
to below 35°C, is a life-threatening condition. Patients with malnutrition and
diabetes mellitus as well as those of advanced age are at high risk for accidental
hypothermia. Due to the high mortality rates of acciden..
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Nephrology / Original Article
Renal adverse effects of sunitinib and its clinical significance: a single-center experience in Korea
Seon Ha Baek, Hyunsuk Kim, Jeonghwan Lee, Dong Ki Kim, Kook-Hwan Oh, Yon Su Kim, Jin Suk Han, Tae Min Kim, Se-Hoon Lee, Kwon-Wook Joo
Korean J Intern Med. 2014;29(1):40-48. Published online January 2, 2014
Background/Aims: Sunitinib is an oral multitargeted tyrosine kinase inhibitor
used mainly for the treatment of metastatic renal cell carcinoma. The renal adverse
effects (RAEs) of sunitinib have not been investigated. The aim of this study
was to determine the incidence and risk factors of RAEs (..
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Nephrology / Original Article
Clinical characteristics and outcomes in renal transplant recipients with renal cell carcinoma in the native kidney
In O Sun, Yu Mi Ko, Eun Young Kim, Kyung Seon Park, Hong Soon Jung, Sun Hye Ko, Byung Ha Chung, Bum Soon Choi, Cheol Whee Park, Yong Soo Kim, Chul Woo Yang
Korean J Intern Med. 2013;28(3):347-351. Published online May 1, 2013
Background/AimsWe investigated the incidence and clinical characteristics of renal cell carcinoma (RCC) in the native kidney of renal transplant recipients. MethodsBetween 1991 and 2010, 1,425 patients underwent kidney transplantation at our ins..
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Nephrology / Original Article
Tissue Doppler-derived E/e' ratio as a parameter for assessing diastolic heart failure and as a predictor of mortality in patients with chronic kidney disease
Min Keun Kim, Biro Kim, Jun Young Lee, Jae Seok Kim, Byoung-Geun Han, Seung Ok Choi, Jae Won Yang
Korean J Intern Med. 2013;28(1):35-44. Published online December 28, 2012
Background/AimsDiastolic dysfunction occurs frequently in patients with chronic kidney disease (CKD) and is associated with heart failure (HF) or mortality. We investigated whether the ratio of early diastolic mitral inflow velocity to early diastolic mitral annulus velocity (..
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Letter to the editor
Cytomegalovirus Induced Interstitial Nephritis and Ureteral Stenosis in Renal Transplant Recipient
Sung Ha Bae, Byung Ha Chung, Yun Kyung Park, Kwanhoon Jo, Chul Woo Yang, Yong-Soo Kim, Bum Soon Choi
Korean J Intern Med. 2012;27(4):470-473. Published online November 27, 2012
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Case Report
Acute Kidney Injury due to Sodium Bromate Intoxication: A Report of Two Cases
Dong Hwan Ryu, Kyung Ae Jang, Seok Min Kim, Jong Won Park, Jun Young Do, Kyung Woo Yoon
Korean J Intern Med. 2011;26(4):463-465. Published online November 28, 2011
Sodium bromate is a strong oxidant used as a neutralizing solution in hair permanents, as well as an auxiliary agent in printing and dyeing. Accidental or deliberate ingestion of bromate solution has rarely been reported in Korea. The clinical manifestations of bromate intoxication are vomiting, ..
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Original Article
Cyclosporin A Inhibits Albumin Synthesis in Huh7 Cells
Youn Joo Jeon, Yong Soo Kim
Korean J Intern Med. 2011;26(3):314-319. Published online September 13, 2011
Background/AimsHypoalbuminemia occurs frequently in renal transplant recipients immediately after renal transplantation. We studied the regulation of hepatic albumin synthesis by cyclosporin A (CsA) in Huh7 cells. MethodsHuh7 cells were incubate..
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Original Article
Role of IL-1α in Cisplatin-Induced Acute Renal Failure in Mice
Jay-Wook Lee, Woo-Jin Nam, Min-Jee Han, Jung-Ho Shin, Jin-Gun Kim, Su-Hyun Kim, Hye-Ryoun Kim, Dong-Jin Oh
Korean J Intern Med. 2011;26(2):187-194. Published online June 1, 2011
Background/AimsFor unknown reasons, caspase-1 -/- mice, protected against cisplatin-induced acute renal failure (ARF), are deficient in interleukin (IL)-1α. We thus asked whether IL-1α deficiency underlies the mechanism of protection against cisplatin-induced ARF in these mic..
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Review
Current Status of Dialysis Therapy in Korea
Dong Chan Jin
Korean J Intern Med. 2011;26(2):123-131. Published online June 1, 2011
The number of patients with end-stage renal disease (ESRD) is rising very rapidly as the number of elderly and patients with diabetes increases in Korea. ESRD Registry Committee of the Korean Society of Nephrology (KSN) collected dialysis therapy data in Korea through an online registry program o..
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Original Article
Comparison of Clinical Outcomes by Different Renal Replacement Therapy in Patients with End-Stage Renal Disease Secondary to Lupus Nephritis
Seok-Hui Kang, Byung-Ha Chung, Sun-Ryoung Choi, Ja-Young Lee, Hoon-Suk Park, In-O Sun, Bum-Soon Choi, Cheol-Whee Park, Yong-Soo Kim, Chul-Woo Yang
Korean J Intern Med. 2011;26(1):60-67. Published online March 2, 2011
Background/AimsMany studies have compared patients with systemic lupus erythematosus (SLE) on renal replacement therapy (RRT) with non-lupus patients. However, few data are available on the long-term outcome of patients with end-stage renal disease (ESRD) secondary to SLE who ..
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Review
PPARγ Agonist Beyond Glucose Lowering Effect
Akira Sugawara, Akira Uruno, Masataka Kudo, Ken Matsuda, Chul Woo Yang, Sadayoshi Ito
Korean J Intern Med. 2011;26(1):19-24. Published online March 2, 2011
The nuclear hormone receptor PPARγ is activated by several agonists, including members of the thiazolidinedione group of insulin sensitizers. Pleiotropic beneficial effects of these agonists, independent of their blood glucose-lowering effects, have recently been demonstrated in the vasculature...
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Original Article
Changing Donor Source Pattern for Kidney Transplantation over 40 Years: A Single-Center Experience
Byung Ha Chung, Mi Hyang Jung, Sung Ha Bae, Suk Hui Kang, Hyeon Seok Hwang, Bok Jin Hyoung, So Young Lee, Youn Ju Jeon, Bum Soon Choi, Cheol Whee Park, Yong-Soo Kim, Ji-Il Kim, In Sung Moon, Chul Woo Yang
Korean J Intern Med. 2010;25(3):288-293. Published online August 31, 2010
Background/AimsKidney transplantations at our center rely mainly on living donors. The purpose of this study was to suggest future donor supply directions by reviewing changing trends in donor type. MethodsDuring the past 40 years, 1,690 kidney ..
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Original Article
The Risk Factors and Outcome of Acute Kidney Injury in the Intensive Care Units
Woo Young Park, Eun Ah Hwang, Mi Hyun Jang, Sung Bae Park, Hyun Chul Kim
Korean J Intern Med. 2010;25(2):181-187. Published online June 1, 2010
Background/AimsAcute kidney injury (AKI) is a common and serious complication in critically ill patients, especially in the intensive care unit (ICU). The present study was performed to evaluate the occurrence rate of AKI using the RIFLE (increasing severity classes risk, inju..
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Case Report
A Case of Rhabdomyolysis Associated with Use of a Pneumatic Tourniquet during Arthroscopic Knee Surgery
Yong Gu Lee, Woong Park, Sang Hoon Kim, Sang Pil Yun, Hun Jeong, Hyung Jong Kim, Dong Ho Yang
Korean J Intern Med. 2010;25(1):105-109. Published online February 26, 2010
The common causes of rhabdomyolysis include trauma, hypoxia, drugs, toxins, infections and hyperthermia. Operative insults, including direct trauma and ischemia, have the potential to cause the development of rhabdomyolysis. Pneumatic tourniquets used during arthroscopic knee surgery to prevent b..
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Original Article
Natural History and Renal Pathology in Patients with Isolated Microscopic Hematuria
Byung Soo Kim, Yong Kyun Kim, Young Shin Shin, Young Ok Kim, Ho Cheol Song, Yong Soo Kim, Euy Jin Choi
Korean J Intern Med. 2009;24(4):356-361. Published online November 27, 2009
Background/AimsNo definite conclusions have been reached about the natural history of patients with isolated microscopic hematuria (IMH). In this study, we observed the natural history of patients with IMH and examined factors related to a pathologic diagnosis and subsequent p..
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Original Article
The Efficacy and Safety of Ezetimibe and Low-Dose Simvastatin as a Primary Treatment for Dyslipidemia in Renal Transplant Recipients
Hye Eun Yoon, Joon Chang Song, Bok Jin Hyoung, Hyeon Seok Hwang, So Young Lee, Youn Joo Jeon, Bum Soon Choi, Yong Soo Kim, Chul Woo Yang
Korean J Intern Med. 2009;24(3):233-237. Published online August 26, 2009
Background/AimsThe efficacy and safety of a combination of ezetimibe and low-dose statin as primary treatment for dyslipidemia in renal transplant patients were evaluated prospectively. MethodsThe study enrolled 77 renal transplant recipients wi..
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Review
Autosomal Dominant Polycystic Kidney Disease: 2009 Update for Internists
William M. Bennett
Korean J Intern Med. 2009;24(3):165-168. Published online August 26, 2009
Because autosomal dominant polycystic kidney disease (ADPKD) is one of the most common genetic abnormalities seen in today's medical practice, many internists will likely treat patients affected by this condition. Genetic abnormalities have been increasingly recognized, and the pathophysiology of..
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