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Pulmonology / Original Article
The start of chemotherapy until the end of radiotherapy in patients with limited-stage small cell lung cancer
Kyoung Ju Lee, Eun Joo Lee, Gyu Young Hur, Sang Yeub Lee, Je Hyeong Kim, Chol Shin, Jae Jeong Shim, Kwang Ho In, Kyung Ho Kang, Se Hwa Yoo, Sung Yong Lee
Korean J Intern Med. 2013;28(4):449-455. Published online July 1, 2013
Background/AimsChemotherapy combined with radiation therapy is the standard treatment for limited stage small cell lung cancer (LS-SCLC). Although numerous studies indicate that the overall duration of chemoradiotherapy is the most relevant predictor of outcome, the optimal ch..
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Hemato-oncology / Review
Clinical applications of mesenchymal stem cells
Nayoun Kim, Seok-Goo Cho
Korean J Intern Med. 2013;28(4):387-402. Published online July 1, 2013
Mesenchymal stem cells (MSCs) are self-renewing, multipotent progenitor cells with multilineage potential to differentiate into cell types of mesodermal origin, such as adipocytes, osteocytes, and chondrocytes. In addition, MSCs can migrate to sites of inflammation and exert potent immunosuppress..
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Hemato-oncology / Original Article
Third-line docetaxel chemotherapy for recurrent and metastatic gastric cancer
Ji Hyun Lee, Sung-Hyun Kim, Sung Yong Oh, Suee Lee, Hojin Lee, Hye Jung Lee, Hyo-Jin Kim
Korean J Intern Med. 2013;28(3):314-321. Published online May 1, 2013
Background/AimsTo determine the efficacy and toxicity of docetaxel as a third-line therapy for patients with relapsed gastric cancer who have undergone modified oxaliplatin-fluorouracil (m-FOLFOX)-4 and modified irinotecan-fluorouracil (m-FOLFIRI) regimens.
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Hemato-oncology / Review
Diagnosis and therapy of multiple myeloma
Antonio Palumbo, Chiara Cerrato
Korean J Intern Med. 2013;28(3):263-273. Published online May 1, 2013
Many advances in the treatment of multiple myeloma have been made due to the use of transplantation and the introduction of novel agents including thalidomide, lenalidomide, and bortezomib. The first step is recognizing the symptoms and starting prompt treatment. Different strategies should be se..
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Hemato-oncology / Review
Molecular targeted therapy for advanced gastric cancer
Jong Gwang Kim
Korean J Intern Med. 2013;28(2):149-155. Published online February 27, 2013
Although medical treatment has been shown to improve quality of life and prolong survival, no significant progress has been made in the treatment of advanced gastric cancer (AGC) within the last two decades. Thus, the optimum standard first-line chemotherapy regimen for AGC remains debatable, and..
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Original Article
Clinical Features of Patients on Home Oxygen Therapy Due to Chronic Respiratory Failure at One University Hospital
Kyoung Hee Kim, Tae Yun Park, Eun Sun Kim, Keun Bum Chung, Sang-Min Lee, Jae-Joon Yim, Chul-Gyu Yoo, Young Whan Kim, Sung Koo Han, Seok-Chul Yang
Korean J Intern Med. 2012;27(3):311-316. Published online September 1, 2012
Background/AimsHome oxygen therapy (HOT) costs a great deal every year and demand for the service is growing. In Korea, health insurance has covered HOT since November 1, 2006. The objective of this study was to evaluate clinical features of patients who used long-term HOT due..
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Original Article
Role of Photodynamic Therapy in the Palliation of Obstructing Esophageal Cancer
Hyeon Young Yoon, Young Koog Cheon, Hye Jin Choi, Chan Sup Shim
Korean J Intern Med. 2012;27(3):278-284. Published online September 1, 2012
Background/AimsThe aim of this non-randomized study was to determine the role of photodynamic therapy (PDT) in a multimodal approach for the palliation of advanced esophageal carcinoma. MethodsTwenty consecutive patients with obstructing esophag..
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Review
Practical Treatments for Constipation in Korea
Kyung-Sik Park, Suck-Chei Choi, Moo-In Park, Jeong-Eun Shin, Kee-Wook Jung, Seong-Eun Kim, Tae-Hee Lee, Hoon-Sup Koo,
Korean J Intern Med. 2012;27(3):262-270. Published online September 1, 2012
Constipation is a digestive symptom that is frequently seen in clinical practice. Its prevalence has been reported to be 2% to 20%, depending on geographical region. Despite the rapid development of medical science, systematic studies on constipation have been rarely conducted in Korea. Recently,..
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Case Report
Development of Brugada Syndrome Following Photodynamic Therapy in a Patient with Cholangiocarcinoma
Duk Won Bang, Min Su Hyon, Young Duk Cho, Sung Koo Kim, Young Joo Kwon
Korean J Intern Med. 2012;27(1):95-97. Published online February 28, 2012
Brugada syndrome can be unmasked by several conditions including a febrile state, marked leukocytosis, and electrolyte disturbances. Herein, we describe a 62-year-old man with cholangiocarcinoma in the first reported case of Brugada syndrome onset following photodynamic therapy.
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Original Article
Feasibility of Non-TBI Conditioning with Busulfan and Fludarabine for Allogeneic Stem Cell Transplantation in Lymphoid Malignancy
Ho Cheol Shin, Yoo Jin Lee, Joon Ho Joon Ho, Soo Jung Lee, Byung Woog Kang, Yee Soo Chae, Jong Gwang Kim, Jun Young Choi, Jong Won Seo, Yu Kyung Kim, Jang Soo Suh, Sang Kyun Sohn
Korean J Intern Med. 2012;27(1):72-83. Published online February 28, 2012
Background/AimsThis retrospective study evaluated the transplantation outcomes of patients with adult lymphoid malignancies who received chemotherapy-based conditioning with busulfan and fludarabine (BuFlu) and busulfan and cyclophosphamide (BuCy2). Method.. </div>
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<div style="color:#C62F37;font-family:'Noto Sans KR', 'Nanum Gothic', sans-serif;">Review </div>
<a class="artiletitle" href="/journal/view.php?number=162559" onmouseover="showAbstract('162559' );" onmouseout="hideAbstract('162559' );"><b><font>Optimization of Stent Deployment by Intravascular Ultrasound</font></b></a>
<div style="padding-top:2px;padding-left:0px" class="article_authors">Hyuck-Jun Yoon, Seung-Ho Hur</div>
<div style="padding-top:2px;padding-left:0px" class="article_issue">
<em>Korean J Intern Med.</em> 2012;27(1):30-38. Published online February 28, 2012 </div>
<div class="doi">DOI: <a href="https://doi.org/10.3904/kjim.2012.27.1.30"><font class="doi">https://doi.org/10.3904/kjim.2012.27.1.30</font></a>
<a href="/journal/CitedByRenew.php?number=162559" onclick="window.open(this.href, 'CrossRef Citedby', 'width=800,height=800,scrollbars=yes');return false;" style="color:#DD434F;font-size:10pt;"> Crossref 28</a>
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<a href='/journal/view.php?number=162559' style='text-decoration:underline;color:#2046f8'><img src='/image/button/fulltext.gif' alt='Full Text' /></a> <a href='/journal/view.php?viewtype=pubreader&number=162559' style='text-decoration:underline;color:#2046f8'><img src='/image/button/pubreader.gif' alt='PubReader' /></a> <a style='cursor: pointer;' onclick='journal_download("epub", "162559", "path=L2hvbWUvdmlydHVhbC9rYWltL2pvdXJuYWwvdXBsb2FkL2VwdWIva2ppbS0yNy0zMC5lcHVi&filename=a2ppbS0yNy0zMC5lcHVi")'><img src='/image/button/epub.gif' alt='ePub' /></a> <a style='cursor: pointer;' onclick='journal_download("pdf", "162559", "kjim-27-30.pdf")'><img src='/image/button/pdf.gif' alt='PDF' /></a> </div>
<div id="162559" style="display:none;padding-top:10px;padding-left:0px; color:#7b7b7b">
<p>Intravascular ultrasound (IVUS) is a useful diagnostic method that provides valuable information in addition to angiography regarding the coronary vessel lumen, dimensions, plaque burden, and characteristics. The major use of IVUS in coronary intervention is to guide interventional strategies and.. </div>
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<div style="color:#C62F37;font-family:'Noto Sans KR', 'Nanum Gothic', sans-serif;">Review </div>
<a class="artiletitle" href="/journal/view.php?number=162537" onmouseover="showAbstract('162537' );" onmouseout="hideAbstract('162537' );"><b><font>Recent Advances in Mechanisms and Treatments of Airway Remodeling in Asthma: A Message from the Bench Side to the Clinic</font></b></a>
<div style="padding-top:2px;padding-left:0px" class="article_authors">Jae Youn Cho</div>
<div style="padding-top:2px;padding-left:0px" class="article_issue">
<em>Korean J Intern Med.</em> 2011;26(4):367-383. Published online November 28, 2011 </div>
<div class="doi">DOI: <a href="https://doi.org/10.3904/kjim.2011.26.4.367"><font class="doi">https://doi.org/10.3904/kjim.2011.26.4.367</font></a>
<a href="/journal/CitedByRenew.php?number=162537" onclick="window.open(this.href, 'CrossRef Citedby', 'width=800,height=800,scrollbars=yes');return false;" style="color:#DD434F;font-size:10pt;"> Crossref 38</a>
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<div class="etc" style="padding-top:5px;text-align: right;">
<a href='/journal/view.php?number=162537' style='text-decoration:underline;color:#2046f8'><img src='/image/button/fulltext.gif' alt='Full Text' /></a> <a href='/journal/view.php?viewtype=pubreader&number=162537' style='text-decoration:underline;color:#2046f8'><img src='/image/button/pubreader.gif' alt='PubReader' /></a> <a style='cursor: pointer;' onclick='journal_download("epub", "162537", "path=L2hvbWUvdmlydHVhbC9rYWltL2pvdXJuYWwvdXBsb2FkL2VwdWIva2ppbS0yNi0zNjcuZXB1Yg==&filename=a2ppbS0yNi0zNjcuZXB1Yg==")'><img src='/image/button/epub.gif' alt='ePub' /></a> <a style='cursor: pointer;' onclick='journal_download("pdf", "162537", "kjim-26-367.pdf")'><img src='/image/button/pdf.gif' alt='PDF' /></a> </div>
<div id="162537" style="display:none;padding-top:10px;padding-left:0px; color:#7b7b7b">
<p>Airway remodeling in asthma is a result of persistent inflammation and epithelial damage in response to repetitive injury. Recent studies have identified several important mediators associated with airway remodeling in asthma, including transforming growth factor-β, interleukin (IL)-5, basic fib.. </div>
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<div style="color:#C62F37;font-family:'Noto Sans KR', 'Nanum Gothic', sans-serif;">Case Report </div>
<a class="artiletitle" href="/journal/view.php?number=162512" onmouseover="showAbstract('162512' );" onmouseout="hideAbstract('162512' );"><b><font>Application of Helical Tomotherapy for Two Cases of Advanced Hepatocellular Carcinoma</font></b></a>
<div style="padding-top:2px;padding-left:0px" class="article_authors">Joon Sung Kim, Chan Ran You, Jeong Won Jang, Si-Hyun Bae, Jong Yong Choi, Seung Kew Yoon, Chul Seung Kay</div>
<div style="padding-top:2px;padding-left:0px" class="article_issue">
<em>Korean J Intern Med.</em> 2011;26(2):201-206. Published online June 1, 2011 </div>
<div class="doi">DOI: <a href="https://doi.org/10.3904/kjim.2011.26.2.201"><font class="doi">https://doi.org/10.3904/kjim.2011.26.2.201</font></a>
<a href="/journal/CitedByRenew.php?number=162512" onclick="window.open(this.href, 'CrossRef Citedby', 'width=800,height=800,scrollbars=yes');return false;" style="color:#DD434F;font-size:10pt;"> Crossref 2</a>
</div>
<div class="etc" style="padding-top:5px;text-align: right;">
<a href='/journal/view.php?number=162512' style='text-decoration:underline;color:#2046f8'><img src='/image/button/fulltext.gif' alt='Full Text' /></a> <a href='/journal/view.php?viewtype=pubreader&number=162512' style='text-decoration:underline;color:#2046f8'><img src='/image/button/pubreader.gif' alt='PubReader' /></a> <a style='cursor: pointer;' onclick='journal_download("epub", "162512", "path=L2hvbWUvdmlydHVhbC9rYWltL2pvdXJuYWwvdXBsb2FkL2VwdWIva2ppbS0yNi0yMDEuZXB1Yg==&filename=a2ppbS0yNi0yMDEuZXB1Yg==")'><img src='/image/button/epub.gif' alt='ePub' /></a> <a style='cursor: pointer;' onclick='journal_download("pdf", "162512", "kjim-26-201.pdf")'><img src='/image/button/pdf.gif' alt='PDF' /></a> </div>
<div id="162512" style="display:none;padding-top:10px;padding-left:0px; color:#7b7b7b">
<p>The role of radiotherapy in the treatment of hepatocellular carcinoma (HCC) has been limited to date, because the liver has a low tolerance to radiation. However, reconstructing tumors and surrounding organs via a three-dimensional conformal planning system can avoid excess radiotherapy exposure .. </div>
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<div style="color:#C62F37;font-family:'Noto Sans KR', 'Nanum Gothic', sans-serif;">Original Article </div>
<a class="artiletitle" href="/journal/view.php?number=162504" onmouseover="showAbstract('162504' );" onmouseout="hideAbstract('162504' );"><b><font>Endoscopic Cryotherapy of Lung and Bronchial Tumors: A Systematic Review</font></b></a>
<div style="padding-top:2px;padding-left:0px" class="article_authors">Seon-Heui Lee, Won-Jung Choi, Sook-Whan Sung, Young-Kyoon Kim, Chi-Hong Kim, Jae-Il Zo, Kwang-Joo Park</div>
<div style="padding-top:2px;padding-left:0px" class="article_issue">
<em>Korean J Intern Med.</em> 2011;26(2):137-144. Published online June 1, 2011 </div>
<div class="doi">DOI: <a href="https://doi.org/10.3904/kjim.2011.26.2.137"><font class="doi">https://doi.org/10.3904/kjim.2011.26.2.137</font></a>
<a href="/journal/CitedByRenew.php?number=162504" onclick="window.open(this.href, 'CrossRef Citedby', 'width=800,height=800,scrollbars=yes');return false;" style="color:#DD434F;font-size:10pt;"> Crossref 23</a>
</div>
<div class="etc" style="padding-top:5px;text-align: right;">
<a href='/journal/view.php?number=162504' style='text-decoration:underline;color:#2046f8'><img src='/image/button/fulltext.gif' alt='Full Text' /></a> <a href='/journal/view.php?viewtype=pubreader&number=162504' style='text-decoration:underline;color:#2046f8'><img src='/image/button/pubreader.gif' alt='PubReader' /></a> <a style='cursor: pointer;' onclick='journal_download("epub", "162504", "path=L2hvbWUvdmlydHVhbC9rYWltL2pvdXJuYWwvdXBsb2FkL2VwdWIva2ppbS0yNi0xMzcuZXB1Yg==&filename=a2ppbS0yNi0xMzcuZXB1Yg==")'><img src='/image/button/epub.gif' alt='ePub' /></a> <a style='cursor: pointer;' onclick='journal_download("pdf", "162504", "kjim-26-137.pdf")'><img src='/image/button/pdf.gif' alt='PDF' /></a> </div>
<div id="162504" style="display:none;padding-top:10px;padding-left:0px; color:#7b7b7b">
<sec><title>Background/AimsWe made a systematic review and evaluation of endoscopic cryotherapy of endobronchial tumors, investigating safety and efficacy. MethodsQualified studies regarding endoscopic cryotherapy of lung tumors were systemically evaluated ..
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Case Report
Successful Treatment of Stereotactic Body Radiation Therapy Combined with Transarterial Chemolipiodolization for Hepatocellular Carcinoma with Biliary Obstruction
Chan-Kwon Park, Si-Hyun Bae, Hong-Jun Yang, Ho-Jong Chun, Il-Bong Choi, Jong-Young Choi, Seung-Kew Yoon
Korean J Intern Med. 2011;26(1):94-98. Published online March 2, 2011
Conventional radiation therapy (RT) is a widely recognized treatment for hepatocellular carcinoma (HCC). However, conventional RT plays only a limited role in HCC treatment because of its low efficacy and the low tolerance of the liver for this modality. Stereotactic body radiation therapy (SBRT)..
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Original Article
Regional Anticoagulation with Citrate is Superior to Systemic Anticoagulation with Heparin in Critically Ill Patients Undergoing Continuous Venovenous Hemodiafiltration
Joon-Sung Park, Gheun-Ho Kim, Chong Myung Kang, Chang Hwa Lee
Korean J Intern Med. 2011;26(1):68-75. Published online March 2, 2011
Background/AimsShort hemofilter survival and anticoagulation-related life-threatening complications are major problems in systemic anticoagulation with heparin (SAH) for continuous renal replacement therapy (CRRT). The present study examined if regional anticoagulation with ci..
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Review
The Role of Photodynamic Therapy for Hilar Cholangiocarcinoma
Young Koog Cheon
Korean J Intern Med. 2010;25(4):345-352. Published online November 27, 2010
The prognosis for hilar cholangiocarcinoma is limited by tumor spread along the biliary tree leading to refractory obstructive cholestasis, cholangitis, and liver failure. Palliation with biliary endoprostheses results in median survival times of 4-6 months for advanced bile duct cancer. Photodyn..
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Original Article
Severe Pulmonary Adverse Effects in Lymphoma Patients Treated with Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (CHOP) Regimen Plus Rituximab
Kyu-Hyoung Lim, Ho-Il Yoon, Young Ae Kang, Keun-Wook Lee, Jee Hyun Kim, Soo-Mee Bang, Jae Ho Lee, Choon-Taek Lee, Jong Seok Lee
Korean J Intern Med. 2010;25(1):86-92. Published online February 26, 2010
Background/AimsThe aim of our study was to determine the incidence and clinical features of severe pulmonary complications in patients receiving cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) or rituximab plus CHOP (R-CHOP) as the initial treatment for lymph..
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Original Article
Clinical Characteristics of Pulmonary Embolism with Underlying Malignancy
Ji Eun Lee, Hye-Ryoun Kim, Sang-Min Lee, Jae-Joon Yim, Chul-Gyu Yoo, Young Whan Kim, Sung Koo Han, Young-Soo Shim, Seok-Chul Yang
Korean J Intern Med. 2010;25(1):66-70. Published online February 26, 2010
Background/AimsThe risk of venous thromboembolism (VTE), which encompasses deep vein thrombosis and pulmonary embolism (PE), increases in patients with cancer. Anticancer treatment is also associated with an increased risk for VTE. We conducted this study to investigate the cl..
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Case Report
Acute Embolic Occlusion of the Left Common Iliac Artery Treated With Intra-Arterial Thrombolysis and Percutaneous Thrombectomy
Wang-Soo Lee, Kwang Je Lee, Wang Seong Ryu
Korean J Intern Med. 2009;24(2):153-155. Published online June 8, 2009
Acute embolic occlusion of the common iliac artery is a rare medical emergency that is not only limb-threatening, but also potentially life-threatening. Several treatment options exist for acute limb ischemia, although no treatment is clearly best. We report a case of acute embolic occlusion of t..
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