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Endocrinology-metabolism / Original Article
Adipokines, insulin-like growth factor binding protein-3 levels, and insulin sensitivity in women with polycystic ovary syndrome
Hyejin Lee, Jee-Young Oh, Yeon-Ah Sung
Korean J Intern Med. 2013;28(4):456-463. Published online July 1, 2013
Background/AimsMany women with polycystic ovary syndrome (PCOS) exhibit insulin resistance. Adipose tissue plays an important role in insulin resistance, and adipokines including tumor necrosis factor (TNF)-α and adiponectin are altered in PCOS. Insulin-like growth factor bin..
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Pulmonology / Original Article
The start of chemotherapy until the end of radiotherapy in patients with limited-stage small cell lung cancer
Kyoung Ju Lee, Eun Joo Lee, Gyu Young Hur, Sang Yeub Lee, Je Hyeong Kim, Chol Shin, Jae Jeong Shim, Kwang Ho In, Kyung Ho Kang, Se Hwa Yoo, Sung Yong Lee
Korean J Intern Med. 2013;28(4):449-455. Published online July 1, 2013
Background/AimsChemotherapy combined with radiation therapy is the standard treatment for limited stage small cell lung cancer (LS-SCLC). Although numerous studies indicate that the overall duration of chemoradiotherapy is the most relevant predictor of outcome, the optimal ch..
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Gastroenterology / Original Article
Effects of D-002, a mixture of high molecular weight beeswax alcohols, on patients with nonalcoholic fatty liver disease
José Illnait, Iván Rodríguez, Sarahí Mendoza, Yolanda Fernández, Rosa Mas, Mirtha Miranda, Jesús Piñera, Julio César Fernández, Meilis Mesa, Lilia Fernández, Daisy Carbajal, Rafael Gámez
Korean J Intern Med. 2013;28(4):439-448. Published online July 1, 2013
Background/AimsNonalcoholic fatty liver disease (NAFLD) is intimately related to insulin resistance and ranges from a benign course to liver fibrosis and cirrhosis. NAFLD management mainly involves dietary modification and weight loss. Although no fully successful pharmacologi..
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Gastroenterology / Original Article
Factors influencing hepatocellular carcinoma prognosis after hepatectomy: a single-center experience
Sung Keun Park, Young Kul Jung, Dong Hae Chung, Keon Kuk Kim, Yeon Ho Park, Jung Nam Lee, Oh Sang Kwon, Yun Soo Kim, Duck Joo Choi, Ju Hyun Kim
Korean J Intern Med. 2013;28(4):428-438. Published online July 1, 2013
Background/AimsRecurrence after hepatic resection is one of the most important factors impacting the prognosis and survival of patients with hepatocellular carcinoma (HCC). We identified prognostic factors affecting overall survival (OS) and disease-free survival (DFS) in pati..
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Nephrology / Original Article
The dose of cyclophosphamide for treating paraquat-induced rat lung injury
Jae-Sung Choi, Sung-Shick Jou, Mee-Hye Oh, Young-Hee Kim, Min-Ju Park, Hyo-Wook Gil, Ho-Yeon Song, Sae-Yong Hong
Korean J Intern Med. 2013;28(4):420-427. Published online July 1, 2013
Background/AimsCyclophosphamide (CP) is a promising treatment for severe cases of paraquat (PQ) poisoning. We investigated the effective dose of CP for mitigating PQ-induced lung injury. MethodsAdult male Sprague-Dawley rats were allocated into ..
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Gastroenterology / Original Article
Recent trends in hepatitis B virus infection in the general Korean population
Hyuck Kim, A Ri Shin, Hoe Hoon Chung, Min Kyoung Kim, Ji Sung Lee, Jae-Jun Shim, Byung-Ho Kim
Korean J Intern Med. 2013;28(4):413-419. Published online July 1, 2013
Background/AimsHepatitis B virus (HBV) is the major cause of chronic liver disease in Korea, but viral prevalence has decreased because of hepatitis B vaccination programs. In this study, we investigated longitudinal changes in HBV in fection in the general Korean population.<..
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Infectious diseases / Review
Vaccines against Coccidioides
Hee Jung Yoon, Karl V. Clemons
Korean J Intern Med. 2013;28(4):403-407. Published online July 1, 2013
Vaccines against fungal diseases are gaining attention because of their growing impact on modern medicine. Development of these vaccines should incorporate immunological tools that integrate with or replace chemotherapy to minimize antibiotic use and consequent resistance. In this review, we eval..
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Hemato-oncology / Review
Clinical applications of mesenchymal stem cells
Nayoun Kim, Seok-Goo Cho
Korean J Intern Med. 2013;28(4):387-402. Published online July 1, 2013
Mesenchymal stem cells (MSCs) are self-renewing, multipotent progenitor cells with multilineage potential to differentiate into cell types of mesodermal origin, such as adipocytes, osteocytes, and chondrocytes. In addition, MSCs can migrate to sites of inflammation and exert potent immunosuppress..
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Letter to the editor
A case of polymyositis associated with Hashimoto's thyroiditis
Shi Jung Sung, Se Jin Hwang, Jong Min Kim, Young Am Lee, Ji Seon Oh, Jae Hee Suh, Seung Won Choi
Korean J Intern Med. 2013;28(3):380-382. Published online May 1, 2013
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Letter to the editor
Successful treatment of recurrent follicular B-cell lymphoma with clarithromycin, prednisolone, and cyclophosphamide
Masashi Ohe, Satoshi Hashino
Korean J Intern Med. 2013;28(3):377-379. Published online May 1, 2013
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Letter to the editor
The renoprotective effects of pentoxifylline: beyond its role in diabetic nephropathy
Shailendra Kapoor
Korean J Intern Med. 2013;28(3):374-376. Published online May 1, 2013
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Letter to the editor
Spontaneous coronary artery dissection diagnosed by intravascular ultrasound and followed up by cardiac computed tomography
Sang-Woong Choi, Chang-Wook Nam, Han-Jun Bae, Yun-Kyeong Cho, Hyuck-Jun Yoon, Seung-Ho Hur, Kwon-Bae Kim
Korean J Intern Med. 2013;28(3):370-373. Published online May 1, 2013
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Case Report
A case of ruptured renal cortical arteriovenous malformation of the right testicular vein in hemorrhagic fever with renal syndrome
Seung Min Lee, Hong Dae Kim, Young-Ki Lee, Jung Woo Noh
Korean J Intern Med. 2013;28(3):365-369. Published online May 1, 2013
Hemorrhagic fever with renal syndrome (HFRS) is an acute viral disease characterized by fever, hemorrhage, and renal failure. Among the various hemorrhagic complications of HFRS, the spontaneous rupture of an arteriovenous malformation of the testicular vessels with a retroperitoneal hematoma is ..
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Case Report
A case of mediastinal ectopic thyroid presenting with a paratracheal mass
Eun Roh, Eun Shil Hong, Hwa Young Ahn, So-Yeon Park, Ho Il Yoon, Kyong Soo Park, Young Joo Park
Korean J Intern Med. 2013;28(3):361-364. Published online May 1, 2013
Mediastinal ectopic thyroid is a very rare condition, with few reported cases in the literature and no reported cases in Korea. This report describes an asymptomatic 65-year-old man with a right paratracheal mass compressing the superior vena. Additionally, the epidemiology, clinical manifestatio..
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Case Report
Synephrine-containing dietary supplement precipitating apical ballooning syndrome in a young female
Hyemoon Chung, Sung Woo Kwon, Tae Hoon Kim, Ji Hyun Yoon, Dae Won Ma, Yoo Mi Park, Bum-Kee Hong
Korean J Intern Med. 2013;28(3):356-360. Published online May 1, 2013
Apical ballooning syndrome (ABS) is a unique reversible cardiomyopathy that is frequently precipitated by emotional or physical stress. In addition, the few drugs reported to precipitate ABS were either illegal or strictly controlled for medical use. This paper reports a case of ABS precipitated ..
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Case Report
A case of hemophagocytic syndrome in a patient with fulminant ulcerative colitis superinfected by cytomegalovirus
Jun Il Mun, Sung Jae Shin, Byung Hyun Yu, Jee Hoon Koo, Dong Hoon Kim, Ki Myoung Lee, Kwang Jae Lee
Korean J Intern Med. 2013;28(3):352-355. Published online May 1, 2013
Hemophagocytic syndrome (HPS) is an uncommon hematological disorder that manifests as fever, splenomegaly, and jaundice, with hemophagocytosis in the bone marrow and other tissues pathologically. Secondary HPS is associated with malignancy and infection, especially viral infection. The prevalence..
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Nephrology / Original Article
Clinical characteristics and outcomes in renal transplant recipients with renal cell carcinoma in the native kidney
In O Sun, Yu Mi Ko, Eun Young Kim, Kyung Seon Park, Hong Soon Jung, Sun Hye Ko, Byung Ha Chung, Bum Soon Choi, Cheol Whee Park, Yong Soo Kim, Chul Woo Yang
Korean J Intern Med. 2013;28(3):347-351. Published online May 1, 2013
Background/AimsWe investigated the incidence and clinical characteristics of renal cell carcinoma (RCC) in the native kidney of renal transplant recipients. MethodsBetween 1991 and 2010, 1,425 patients underwent kidney transplantation at our ins..
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Endocrinology-metabolism / Original Article
Low glibenclamide concentrations affect endoplasmic reticulum stress in INS-1 cells under glucotoxic or glucolipotoxic conditions
Min Jeong Kwon, Hye Suk Chung, Chang Shin Yoon, Eun Ju Lee, Tae Kyun Kim, Soon Hee Lee, Kyung Soo Ko, Byoung Doo Rhee, Mi Kyung Kim, Jeong Hyun Park
Korean J Intern Med. 2013;28(3):339-346. Published online May 1, 2013
Background/Aimsβ-Cell apoptosis caused by increased endoplasmic reticulum (ER) stress is an important pathogenic component of type 2 diabetes mellitus. In theory, sulfonylureas, used for the treatment of diabetes, can contribute to ER stress. We assessed changes in ER stress ..
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Pulmonology / Original Article
Relationship between bronchial anthracofibrosis and endobronchial tuberculosis
Hyun Ji Kim, Sang Dong Kim, Dong Woo Shin, Soo Hyun Bae, Ah Lim Kim, Ji Na Kim, Seung Wook Jung, Byung Ki Lee, Yeon Jae Kim
Korean J Intern Med. 2013;28(3):330-338. Published online May 1, 2013
Background/AimsVarious pulmonary diseases may be associated with bronchial anthracofibrosis (BAF). Our aim was to identify a relationship between BAF and endobronchial tuberculosis (EBTB). MethodsIn total, 156 patients, diagnosed with EBTB using..
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Gastroenterology / Original Article
A comparison of the BISAP score and serum procalcitonin for predicting the severity of acute pancreatitis
Byung Geun Kim, Myung Hwan Noh, Choong Heon Ryu, Hwa Seong Nam, Su Mi Woo, Seung Hee Ryu, Jin Seok Jang, Jong Hun Lee, Seok Ryeol Choi, Byeong Ho Park
Korean J Intern Med. 2013;28(3):322-329. Published online May 1, 2013
Background/AimsThe bedside index of severity in acute pancreatitis (BISAP) is a new, convenient, prognostic multifactorial scoring system. As more data are needed before clinical application, we compared BISAP, the serum procalcitonin (PCT), and other multifactorial scoring sy..
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