Heart failure with preserved ejection fraction: insights from recent clinical researches

Mi-Na Kim; Seong-Mi Park

doi:10.3904/kjim.2020.104.e1

Table 1.

Diagnostic of HFA-PEFF [15]

		HFA-PEFF score [15]
		Major		Minor
		Value	Point	Value	Point
Functional		Septal e’ < 7 cm/sec or lateral e’ < 10 cm/sec	2	Avergaed E/e’ 9–14	1
		or		or
		Averaged E/e’ ≥ 15		GLS < 16%
		or
		TR Vmax > 2.8 m/sec (PASP > 35 mmHg)
Morphological		LAVI > 34 mL/m²	2	LAVI 29–34 mL/m²	1
		or		or
		LVMI ≥ 149/122 g/m² (M/W) ± RWT > 0.42		LVMI ≥ 115/95 m² (M/W)
				or
				RWT > 0.42
				or
				LV wall thickness ≥ 12 mm
Biomarker	(SR)	NT-proBNP > 220 pg/mL	2	NT-proBNP 125–220 pg/mL	1
		or		or
		BNP > 80 pg/mL		BNP 35–80 pg/mL
	(AF)	NT-proBNP > 660 pg/mL	2	NT-proBNP 365–660 pg/mL	1
		or		or
		BNP > 240 pg/mL		BNP 105–240 pg/mL

≥ 5 points: heart failure with preserved ejection fraction; 2–4 points: exercise stress test or invasive hymodynamic measurement.

HFA-PEFF, heart Failure Association-PEFF; TR, tricuspid regurgitation; PASP, pulmonary artery systolic pressure; GLS, global longitudinal strain; LAVI, left atrial volume index; LVMI, left ventricular mass index; M/W, men/women; RWT, regional wall thickness; LV, left ventricular; SR, sinus rhythm; NT-proBNP, N-terminal pro-B type natriuretic peptide; BNP, B type natriuretic peptide; AF, atrial fibrillation.

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