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Pretreatment with Darbepoetin Attenuates Renal Injury in a Rat Model of Cisplatin-Induced Nephrotoxicity

Dae Eun Choi, Jin Young Jeong, Beom Jin Lim, Kang Wook Lee, Young-Tai Shin, Ki-Ryang Na

Korean J Intern Med. 2009;24(3):238-246. Published online August 26, 2009

DOI: https://doi.org/10.3904/kjim.2009.24.3.238 Crossref 15

Background/Aims

Darbepoetin alfa (DPO) exhibits comparable renoprotective effects to erythropoietin (EPO) in several animal models of acute renal injury. We examined whether DPO also attenuated renal injury in a rat model of cisplatin nephrotoxicity.

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