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Rheumatology / Original Article
Association of hyperuricemia with valvular heart disease and the modifying effect of obesity
Seung Min Jung, Sang-Hyuk Jung, Su-Nam Lee, Jin A Choi, Dokyoon Kim, Hong-Hee Won, Jae-Seung Yun
Korean J Intern Med. 2026;41(4):748-762. Published online July 1, 2026
Background/Aims: Hyperuricemia has been widely associated with cardiovascular health, but its relationship with incident valvular heart disease (VHD) remains uncertain. This study investigated the association between hyperuricemia and VHD, and further explored the role of weight management within thi..
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Endocrinology-metabolism / Original Article
Association between diabetes duration and hyperuricemia: Korea National Health and Nutrition Examination Survey 2016 to 2021
Kyuho Kim, Kyungdo Han, In Young Kim, Kyuna Lee, Yu-Bae Ahn, Seung-Hyun Ko, Jae-Seung Yun
Korean J Intern Med. 2026;41(1):143-151. Published online January 1, 2026
Background/Aims: We examined the association between diabetes duration and hyperuricemia in Korean subjects based on data from the Korea National Health and Nutrition Examination Survey (KNHANES).
Methods: This cross-sectional study included 4,575 subjects aged 30 years and older with type 2 diabet..
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Endocrinology-metabolism / Original Article
Fasting glucose level and all-cause or cause-specific mortality in Korean adults: a nationwide cohort study
Yi-Suk Kim, Yong-Moon Park, Kyung-Do Han, Jae-Seung Yun, Yu-Bae Ahn, Seung-Hyun Ko
Korean J Intern Med. 2021;36(3):647-658. Published online July 7, 2020
Background/Aims: Although people with diabetes have been shown to have higher mortality than people without diabetes, there is a lack of data on the association between fasting plasma glucose (FPG) levels and cause-specific mortality rates in the general population.
Methods: A total of 326,547 Kore..
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Endocrinology-metabolism / Original Article
Impaired fasting glucose levels in overweight or obese subjects for screening of type 2 diabetes in Korea
Jin-Hee Lee, Suk Chon, Seon-Ah Cha, Sun-Young Lim, Kook-Rye Kim, Jae-Seung Yun, Sang Youl Rhee, Kun-Ho Yoon, Yu-Bae Ahn, Jeong-Taek Woo, Seung-Hyun Ko; Korean Diabetes Prevention Study Investigators
Korean J Intern Med. 2021;36(2):382-391. Published online March 5, 2020
Background/Aims: We examined the concordance rate among fasting plasma glucose (FPG), 2-hour post-challenge glucose (2hr PG), and hemoglobin A1c (HbA1c) in the diagnosis of diabetes in a population with a high-risk for type 2 diabetes mellitus (T2DM) in Korea.
Methods: Among the participants from th..
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Endocrinology-metabolism / Original Article
Depth and combined infection is important predictor of lower extremity amputations in hospitalized diabetic foot ulcer patients
Eun-Gyo Jeong, Sung Shim Cho, Sang-Hoon Lee, Kang-Min Lee, Seo-Kyung Woo, Yoongoo Kang, Jae-Seung Yun, Seon-Ah Cha, Yoon-Jung Kim, Yu-Bae Ahn, Seung-Hyun Ko, Jung-Min Lee
Korean J Intern Med. 2018;33(5):952-960. Published online June 7, 2017
Background/Aims: As the prevalence of diabetes mellitus and its complications increase rapidly, diabetic foot ulcers (DFUs), which are a major diabetic complication, are expected to increase. For prevention and effective treatment, it is important to understand the clinical course of DFUs. The aim o..
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Endocrinology-metabolism / Original Article
Elevated lipoprotein(a) levels predict cardiovascular disease in type 2 diabetes mellitus: a 10-year prospective cohort study
Tae-Seok Lim, Jae-Seung Yun, Seon-Ah Cha, Ki-Ho Song, Ki-Dong Yoo, Yu-Bae Ahn, Yong-Moon Park, Seung-Hyun Ko
Korean J Intern Med. 2016;31(6):1110-1119. Published online October 18, 2016
Background/Aims: Elevated lipoprotein(a) (Lp[a]) level is known to be a risk factor for cardiovascular disease (CVD). However, the data that has been reported on the association between the Lp(a) level and CVD in type 2 diabetes has been limited and incoherent. The aim of this study was to investiga..
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Endocrinology-metabolism / Review
Avoiding or coping with severe hypoglycemia in patients with type 2 diabetes
Jae-Seung Yun, Seung-Hyun Ko
Korean J Intern Med. 2015;30(1):6-16. Published online December 30, 2014
Hypoglycemia is a major barrier to achieving the glycemic goal in patients with type 2 diabetes. In particular, severe hypoglycemia, which is defined as an event that requires the assistance of another person to actively administer carbohydrates, glucagon, or take other corrective actions, is a seri..
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