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Nephrology / Original Article
Circulating renalase predicts all-cause mortality and renal outcomes in patients with advanced chronic kidney disease
Seon Ha Baek, Ran-hui Cha, Shin Wook Kang, Cheol Whee Park, Dae Ryong Cha, Sung Gyun Kim, Sun Ae Yoon, Sejoong Kim, Sang-Youb Han, Jung Hwan Park, Jae Hyun Chang, Chun Soo Lim, Yon Su Kim, Ki Young Na
Korean J Intern Med. 2019;34(4):858-866. Published online November 29, 2017
Background/Aims: Patients with chronic kidney disease (CKD) have been found to show markedly increased rates of end-stage renal disease, major adverse cardiovascular and cerebrovascular events (MACCEs), and mortality. Therefore, new biomarkers are required for the early detection of such clinical ou..
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Nephrology / Original Article
Time points for obtaining representative values of 24-hour blood pressure in chronic kidney disease
Jiwon Ryu, Ran-hui Cha, Dong Ki Kim, Ju Hyun Lee, Sun Ae Yoon, Dong Ryeol Ryu, Jieun Oh, Sejoong Kim, Sang-Youb Han, Eun Young Lee, Yon Su Kim
Korean J Intern Med. 2015;30(5):665-674. Published online August 27, 2015
Background/Aims: Ambulatory blood pressure (BP) monitoring has been widely recommended for evaluating the status of BP, but is lacking in practicality. Determination of the specific time points for BP measurement that are representative of 24-hour mean BP could be useful and convenient in hypertensi..
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Original Article
Phosphodiesterase Inhibitor Improves Renal Tubulointerstitial Hypoxia of the Diabetic Rat Kidney
Hui-Kyoung Sun, Yun Mi Lee, Kum Hyun Han, Han-Seong Kim, Seon-Ho Ahn, Sang-Youb Han
Korean J Intern Med. 2012;27(2):163-170. Published online May 31, 2012
Background/AimsRenal hypoxia is involved in the pathogenesis of diabetic nephropathy. Pentoxifyllin (PTX), a nonselective phosphodiesterase inhibitor, is used to attenuate peripheral vascular diseases. To determine whether PTX can improve renal hypoxia, we investigated its eff..
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Original Article
Effect of IgA Aggregates on Transforming Growth Factor-β1 Production in Human Mesangial Cells and the Intraglomerular Expression of Transforming Growth Factor-β1 in Patients with IgA Nephropathy
Sang-Youb Han, Chun-Gyoo Ihm, Dae-Ryong Cha, Young-Sun Kang, Kum-Hyun Han, Hyoung-Kyu Kim, Jee-Young Han
Korean J Intern Med. 2005;20(1):40-47. Published online March 31, 2005
BackgroundTransforming growth factor-β (TGF-β) stimulates renal fibrosis in various renal diseases including IgA nephropathy. MethodsWe examined whether immunoglobulin A (IgA) stimulated TGF-β1 synthesis in human mesangial cells (MCs), and whe..
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