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Case Report
Acute Embolic Occlusion of the Left Common Iliac Artery Treated With Intra-Arterial Thrombolysis and Percutaneous Thrombectomy
Wang-Soo Lee, Kwang Je Lee, Wang Seong Ryu
Korean J Intern Med. 2009;24(2):153-155. Published online June 8, 2009
Acute embolic occlusion of the common iliac artery is a rare medical emergency that is not only limb-threatening, but also potentially life-threatening. Several treatment options exist for acute limb ischemia, although no treatment is clearly best. We report a case of acute embolic occlusion of t..
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Case Report
A Case of Hepatocellular Carcinoma Within Hepatocellular Adenoma in a Non-Cirrhotic Male
Dong Hwan Kim, Seung Up Kim, Dong Hyuk Nam, Yoon Jung Choi, Soo Mi Park, Chon Kyun Lee, Do Young Kim
Korean J Intern Med. 2009;24(2):147-152. Published online June 8, 2009
Hepatocellular adenoma (HA) is a benign hepatic lesion that predominantly occurs in young women. Most hepatocellular carcinomas (HCC) arise in a cirrhotic liver during the fifth or sixth decades. There have been several reported cases of HCC developing from HA in female patients. However, there a..
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Case Report
Gastric Yolk Sac Tumor: A Case Report and Review of the Literature
Yeon Soo Kim, Seok Hyun Kim, Jae Koo Seong, Byung Seok Lee, Hyun Yong Jeong, Kyu Sang Song
Korean J Intern Med. 2009;24(2):143-146. Published online June 8, 2009
Gastric yolk sac tumors are extremely rare and their prognosis is poor; most patients have widespread metastases at the time of diagnosis. The treatment of gastric yolk sac tumors consists of aggressive chemotherapy combined with radiotherapy and surgery. Here, we first report a case of gastric y..
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Original Article
Effect of the Combined Use of Tramadol and Milnacipran on Pain Threshold in an Animal Model of Fibromyalgia
Seong-Ho Kim, Junhwa Song, Hyunil Mun, Keon Uk Park
Korean J Intern Med. 2009;24(2):139-142. Published online June 8, 2009
Background/AimsAcidic saline injections produce mechanical hyperresponsiveness in male Sprague-Dawley rats. We investigated the effect of milnacipran in conjunction with tramadol on the pain threshold in an acidic saline animal model of pain. Methods
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Original Article
Diagnosis and Species Identification of Mycobacterial Infections by Polymerase Chain Reaction-Restriction Fragment Length Polymorphism Analysis of Sterile Body Fluids
Cheong Ho Cho, Sang Hoon Han, Bum Sik Chin, Suk Hoon Choi, Han Sung Lee, Chang Oh Kim, Myung Soo Kim, Jun Yong Choi, Young Goo Song, June Myung Kim
Korean J Intern Med. 2009;24(2):135-138. Published online June 8, 2009
Background/AimsThe development of effective, accurate, and rapid diagnostic methods for Mycobacterium infection and mycobacterial species identification is required. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) is an easy, rapi..
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Original Article
Clinicopathologic Characteristics of T-cell Non-Hodgkin's Lymphoma: A Single Institution Experience
Ock Bae Ko, Dae Ho Lee, Sang We Kim, Jung Shin Lee, Shin Kim, Jooryung Huh, Cheolwon Suh
Korean J Intern Med. 2009;24(2):128-134. Published online June 8, 2009
Background/AimsAlthough the incidence of T-cell non-Hodgkin's lymphoma (NHL) is higher in Far East Asia than in Western countries, its incidence and clinical course in Korea are not well-defined. Therefore, we assessed the relative frequency and clinical features of T-cell NHL..
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Original Article
The Pulmonary Embolism Severity Index in Predicting the Prognosis of Patients With Pulmonary Embolism
Won-Ho Choi, Sung Uk Kwon, Yoon Jung Jwa, Jung A Kim, Yun-Ho Choi, Je Ho Chang, Hoon Jung, Joon Hyung Doh, June Namgung, Sung Yun Lee, Won Ro Lee
Korean J Intern Med. 2009;24(2):123-127. Published online June 8, 2009
Background/AimsMany prognostic models have been developed to help physicians make medical decisions on treating patients with pulmonary embolism. Among these models, the Pulmonary Embolism Severity Index (PESI) has been shown to be a successful risk stratification tool for pat..
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Original Article
Cilostazol Protects Endothelial Cells Against Lipopolysaccharide-Induced Apoptosis Through ERK1/2- and P38 MAPK-Dependent Pathways
Jong-Hoon Lim, Jae-Suk Woo, Yung-Woo Shin
Korean J Intern Med. 2009;24(2):113-122. Published online June 8, 2009
Background/AimsWe examined the effects of cilostazol on mitogen-activated protein kinase (MAPK) activity and its relationship with cilostazol-mediated protection against apoptosis in lipopolysaccharide (LPS)-treated endothelial cells. MethodsHum..
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Original Article
The Association Between the Serum Sodium Level and the Severity of Complications in Liver Cirrhosis
Jong Hoon Kim, June Sung Lee, Seuk Hyun Lee, Won Ki Bae, Nam-Hoon Kim, Kyung-Ah Kim, Young-Soo Moon
Korean J Intern Med. 2009;24(2):106-112. Published online June 8, 2009
Background/AimsDilutional hyponatremia associated with liver cirrhosis is caused by impaired free water clearance. Several studies have shown that serum sodium levels correlate with survival in cirrhotic patients. Little is known, however, regarding the relationship between th..
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Original Article
Diagnostic Yield of Tissue Sampling Using a Bite-On-Bite Technique for Incidental Subepithelial Lesions
Jeong-Seon Ji, Bo-In Lee, Kyu-Yong Choi, Byung-Wook Kim, Hwang Choi, Min Huh, Woo-Chul Chung, Hiun-Suk Chae, In-Sik Chung
Korean J Intern Med. 2009;24(2):101-105. Published online June 8, 2009
Background/AimsTechniques for endoscopic evaluation of gastrointestinal subepithelial lesions include conventional endoscopy, jumbo biopsy, endoscopic ultrasonogrphy (EUS), EUS-guided fine needle aspiration, and endoscopic submucosal resection. However, these procedures have m..
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Original Article
Marked Recovery From Paraquat-Induced Lung Injury During Long-Term Follow-up
Kwon-Hyun Lee, Hyo-Wook GIL, Young-Tong Kim, Jong-Oh Yang, Eun-Young Lee, Sae-Yong Hong
Korean J Intern Med. 2009;24(2):95-100. Published online June 8, 2009
Background/AimsParaquat-induced lung injury has been considered a progressive and irreversible disease. The purpose of this study was to report the long-term evolution of lung lesions in eight survivors with significant paraquat-induced lung injuries who could be followed-up f..
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Review
Established and Newly Proposed Mechanisms of Chronic Cyclosporine Nephropathy
Hye Eun Yoon, Chul Woo Yang
Korean J Intern Med. 2009;24(2):81-92. Published online June 8, 2009
Cyclosporine (CsA) has improved patient and graft survival rates following solid-organ transplantation and has shown significant clinical benefits in the management of autoimmune diseases. However, the clinical use of CsA is often limited by acute or chronic nephropathy, which remains a major pro..
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Case Report
An Antinuclear Antibody-Negative Patient With Lupus Nephritis
Hyoun-Ah Kim, Jae-Wook Chung, Han-Jung Park, Dai-Yeol Joe, Hyun-Ee Yim, Hae-Sim Park, Chang-Hee Suh
Korean J Intern Med. 2009;24(1):76-79. Published online March 6, 2009
Systemic lupus erythematosus (SLE) is a typical autoimmune disease that's characterized by various autoantibodies to nuclear and cytoplasmic antigens. The presence of antinuclear antibodies (ANA) in serum is generally considered a decisive diagnostic sign of SLE. However, a small subset of SLE pa..
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Case Report
Successful Treatment of Small-Cell Lung Cancer With Irinotecan in a Hemodialysis Patient With End-Stage Renal Disease
Dong Min Kim, Hyun Lee Kim, Choon Hae Chung, Chi Young Park
Korean J Intern Med. 2009;24(1):73-75. Published online March 6, 2009
The prognosis of patients with end-stage renal disease has improved with advances in hemodialysis techniques. However, many patients who undergo hemodialysis suffer from various types of cancer. Limited data is available to guide clinical management of these patients who may have impaired renal f..
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Case Report
Novel LMNA Gene Mutation in a Patient With Atypical Werner's Syndrome
Yun Jeong Doh, Hee Kyoung Kim, Eui Dal Jung, Seung Hee Choi, Jung Guk Kim, Bo Wan Kim, In Kyu Lee
Korean J Intern Med. 2009;24(1):68-72. Published online March 6, 2009
Hutchinson-Gilford progeria syndrome (HGPS) and Werner's syndrome are representative types of progeroid syndrome. LMNA (Lamin A/C) gene mutation with atypical Werner's syndrome have recently been reported. Atypical Werner's syndrome with the severe metabolic complications, the ex..
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Case Report
Long-Term Survival in a Patient With Ruptured Hepatocellular Carcinoma
Joon Sung Kim, Seung Kew Yoon, Jeong Ah Kim, Chang Wook Kim, Si Hyun Bae, Jong Young Choi, Chan-Kwon Jung
Korean J Intern Med. 2009;24(1):63-67. Published online March 6, 2009
A 57-yr-old woman previously diagnosed with chronic hepatitis B was admitted via the emergency room because she suddenly developed epigastric pain with abdominal distension. On computed tomography (CT), a round enhancing mass was found on the left hepatic lobe with ascites in the peritoneal space..
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Original Article
The Effect of Residual Renal Function at the Initiation of Dialysis on Patient Survival
Seoung Gu Kim, Nam Ho Kim
Korean J Intern Med. 2009;24(1):55-62. Published online March 6, 2009
Background/AimsThe optimal time point for initiating renal replacement therapy in patients with end-stage renal disease remains controversial. The primary objective of our study was to determine the effects of residual renal function at the beginning of renal replacement thera..
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Original Article
EGFR and KRAS Mutations in Patients With Adenocarcinoma of the Lung
Tae Won Jang, Chul Ho Oak, Hee Kyung Chang, Soon Jung Suo, Mann Hong Jung
Korean J Intern Med. 2009;24(1):48-54. Published online March 6, 2009
Background/AimsMutations of the epidermal growth factor receptor (EGFR) and Kirsten rat sarcoma viral oncogene (KRAS) are important in the pathogenesis of lung cancer, and recent reports have revealed racial and geographical differences in mutation expression.
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Original Article
A Comparison of Patient Acceptance and Preferences Between CT Colonography and Conventional Colonoscopy in Colorectal Cancer Screening
Hyuk Sang Jung, Dong Kyun Park, Min Ju Kim, Sang Kyun Yu, Kwang An Kwon, Yang Suh Ku, Yu Kyung Kim, Ju Hyun Kim
Korean J Intern Med. 2009;24(1):43-47. Published online March 6, 2009
Background/AimsColorectal cancer, one of the most common cancers in developed countries, is curable when diagnosed at an early stage. However, for better screening, both a test that patients will tolerate and diagnostic accuracy are required. We compared patient experiences an..
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Original Article
Gemcitabine, Etoposide, Cisplatin, and Dexamethasone in Patients With Refractory or Relapsed Non-Hodgkin's Lymphoma
Ki-Hyang Kim, Young-Don Joo, Chang-Hak Sohn, Ho-Jin Shin, Joo-Seop Chung, Goon-Jae Cho, Sung-Hoon Shin, Yang-Soo Kim, Won-Sik Lee
Korean J Intern Med. 2009;24(1):37-42. Published online March 6, 2009
Background/AimsTo date, an effective salvage chemotherapy regimen for the treatment of refractory or relapsing non-Hodgkin's lymphoma (NHL) has not been discovered. This study was conducted to evaluate the efficacy and safety of gemcitabine, etoposide, cisplatin, and dexametha..
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