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Case Report
Autoimmune Chronic Pancreatitis Relapsing Despite the Maintenance Dose of Steroid
Dae Keun Pyun, Won Beom Choi, Myung Hwan Kim, Jae Pil Yun, Sang Su Lee, Dong Wan Seo, Sung Koo Lee
Korean J Intern Med. 2005;20(2):163-167. Published online June 30, 2005
Autoimmune chronic pancreatitis is a disease characterized by diffuse swelling of the pancreas, irregular narrowing of the main pancreatic duct and elevated levels of serum IgG, and lymphoplasmacytic infiltration is observed on histologic examination. Steroid therapy can dramatically reverse the ..
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Case Report
Kimura's Disease Involving Thoracic and Abdominal Lymph Nodes in a Hemodialysis Patient
Sik Lee, Su Jin Jung, Sung Kwang Park, Kyung Pyo Kang, Kyu Yun Jang, Myoung Jae Kang, Won Kim
Korean J Intern Med. 2005;20(2):159-162. Published online June 30, 2005
We report the first observed case of Kimura's disease occurring during hemodialysis, involving the thoracic and abdominal lymph nodes, which spontaneously resolved nearly completely after two months. Early diagnosis and recognition of Kimura's disease may spare both the patient and doctor from th..
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Original Article
Comparison of Asthma Phenotypes Using Different Sensitizing Protocols in Mice
Yoon-Seok Chang, Yoon-Keun Kim, Joon-Woo Bahn, Sang-Heon Kim, Heung-Woo Park, Tae-Bum Kim, Sang-Heon Cho, Kyung-Up Min, You-Young Kim
Korean J Intern Med. 2005;20(2):152-158. Published online June 30, 2005
BackgroundSeveral methods have been reported to induce asthmatic reactions in mice but few studies have compared their efficiency. We evaluated the efficiency of the protocols frequently used in the literature. MethodsBALB/c mice were sensitized..
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Original Article
Increased Expression of Glucocorticoid Receptorβ Messenger RNA in Patients with Ankylosing Spondylitis
Chang-Keun Lee, Eun Young Lee, You-Sook Cho, Keun Ae Moon, Bin Yoo, Hee-Bom Moon
Korean J Intern Med. 2005;20(2):146-151. Published online June 30, 2005
BackgroundGlucocorticoids have been known to be less effective for treating ankylosing spondylitis (AS) patients than for treating rheumatoid arthritis (RA) patients. To elucidate the mechanisms underlying this phenomenon, we evaluated whether the glucocorticoid receptor (GR)..
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Original Article
Digitized QT dispersion by the Valsalva Maneuver in Hypertensive Patients
Hee-Jeoung Yoon, Seung-Won Jin, Jong-Min Lee, Woo-Seung Shin, Yong-Suk Oh, Man-Young Lee, Ki-Bae Seung, Tai-Ho Rho, Jae-Hyung Kim, Soon-Jo Hong, Kyu-Bo Choi
Korean J Intern Med. 2005;20(2):141-145. Published online June 30, 2005
BackgroundHypertension is an important risk factor for sudden cardiac death, of which the incidence increases with increases in blood pressure. Prolonged QT dispersion has been identified to indicate increased risk of life-threatening ventricular arrhythmia and sudden cardiac ..
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Original Article
The Efficacy of Paclitaxel and Cisplatin Combination Chemotherapy for the Treatment of Metastatic or Recurrent Gastric Cancer: a Multicenter Phase II Study
Sang Joon Shin, Sung Ho Chun, Kyeong Ok Kim, Min Kyoung Kim, Kyung Hee Lee, Myung Soo Hyun, Sung Hwa Bae, Hun Mo Ryoo, Young Rok Do, Ki Young Kwon, Hong Suk Song
Korean J Intern Med. 2005;20(2):135-140. Published online June 30, 2005
BackgroundAlthough many treatments for advanced gastric cancer have been developed, only poor treatment results have generally been obtained. We performed a prospective study on the combination chemotherapy of paclitaxel and cisplatin (PC). The primary objectives of the study ..
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Original Article
Clinical Aspects of Pregnancy and Delivery in Patients with Chronic Idiopathic Thrombocytopenic Purpura (ITP)
Young-Woong Won, Won Moon, Yeong-Seop Yun, Ho-Suk Oh, Jung-Hye Choi, Young-Yeul Lee, In-Soon Kim, Il-Young Choi, Myung-Ju Ahn
Korean J Intern Med. 2005;20(2):129-134. Published online June 30, 2005
BackgroundIdiopathic thrombocytopenic purpura (ITP) is a condition that often develops in young women and, consequently, physicians should frequently manage and monitor pregnant patients with this disorder. MethodsWe reviewed the charts of 30 wo..
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Original Article
The Effects of Methylene Blue on Hemodynamic Parameters and Cytokine Levels in Refractory Septic Shock
Byung-Kyu Park, Tae-Sun Shim, Chae-Man Lim, Sang-Do Lee, Woo-Sung Kim, Dong-Soon Kim, Won-Dong Kim, Younsuck Koh
Korean J Intern Med. 2005;20(2):123-128. Published online June 30, 2005
Background/AimsEndogenous nitric oxide (NO) induces the peripheral vasodilation via the activation of guanylate cyclase in patients with septic shock. The purpose of this study was to assess the acute effects of methylene blue (MB), which is an inhibitor of guanylate cyclase, ..
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Original Article
High Frequency of Microsatellite Instability in Intestinal-type Gastric Cancer in Korean Patients
Won Hyuk Choe, Sun-Young Lee, Jun Haeng Lee, Sang Goon Shim, Young-Ho Kim, Poong-Lyul Rhee, Jong Chul Rhee, Chang-Seok Ki, Jong-Won Kim, Sang Yong Song, Jae J. Kim
Korean J Intern Med. 2005;20(2):116-122. Published online June 30, 2005
BackgroundAlthough there have been some reports on microsatellite alterations in gastric cancer, findings are inconsistent regarding the associations between histological classification and microsatellite instability (MSI). In the present study, we attempted to determine wheth..
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Original Article
Comparison of the Clinical Features of Apical Hypertrophic Cardiomyopathy Versus Asymmetric Septal Hypertrophy in Korea
Hyun Suk Yang, Jae-Kwan Song, Jong-Min Song, Duk-Hyun Kang, Cheol Whan Lee, Myeong-Ki Hong, Jae-Joong Kim, Seong-Wook Park, Seung-Jung Park
Korean J Intern Med. 2005;20(2):111-115. Published online June 30, 2005
BackgroundWe sought to test whether patients with apical hypertrophic cardiomyopathy (APH) have different clinical features compared to those with typical asymmetric septal hypertrophy (ASH). MethodsAmong 32,534 patients who underwent routine ec..
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Case Report
Ovarian Granulosa Cell Tumor presenting as Meigs' Syndrome with elevated CA125
Kwon Choi, Hyun Jong Lee, Ji Cheul Pae, Suk Joong Oh, Seong Yong Lim, Eun Yoon Cho, Seung Sei Lee
Korean J Intern Med. 2005;20(1):105-109. Published online March 31, 2005
Herein, a rare case of ovarian granulosa cell tumor, presenting as Meigs' syndrome, with elevated carbohydrate antigen 125 (CA125), is reported. A 69-year-old woman was admitted for the investigation of abdominal fullness and dyspnea. A preoperative examination revealed a huge pelvic tumor and an..
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Case Report
Malignant Peripheral Nerve Sheath Tumor in Neurofibromatosis Type I : Unusual Presentation of Intraabdominal or Intrathoracic Mass
Jong Gwang Kim, Woo Jin Sung, Dong Hwan Kim, Young Hwan Kim, Sang Kyun Sohn, Kyu Bo Lee
Korean J Intern Med. 2005;20(1):100-104. Published online March 31, 2005
A malignant peripheral nerve sheath tumor (MPNST) is an extremely rare soft tissue tumor in the general population. On the other hand, there is a higher incidence of MPNST in patients with neurofibromatosis type I (von Recklinghausen's disease). The common sites are the extremities, trunk, head a..
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Case Report
An Adult with Aplastic Crisis induced by Human Parvovirus B19 as an Initial Presentation of Hereditary Spherocytosis
Sook Eui Oh, Jung Han Kim, Chi Hun Choi, Kwang Hyuk Park, Joo Young Jung, Young Iee Park, Min-Jeong Park
Korean J Intern Med. 2005;20(1):96-99. Published online March 31, 2005
The association between aplastic crisis and human parvovirus (HPV) B19 infection is well described in patients with sickle cell anemia. This association has also been described, although much less frequently, in patients with hereditary spherocytosis (HS). However, most cases of aplastic crises i..
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Case Report
Renal Transplantation in a Patient with Idiopathic Thrombocytopenic Purpura
Eun Mi Hwang, Hyun Young Woo, Beom Soon Choi, Chul Woo Yang, Yong Soo Kim, In Sung Moon, Byung Kee Bang
Korean J Intern Med. 2005;20(1):92-95. Published online March 31, 2005
The combination of idiopathic thrombocytopenic purpura (ITP) and chronic renal failure (CRF) is uncommon. This report highlights a case of renal transplantation in a patient with ITP. A 35-year-old man with ITP was admitted with uremic symptoms. A renal transplant and splenectomy was simultaneous..
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Case Report
Two Cases of Broncholith Removal under the Guidance of Flexible Bronchoscopy
Ka Yeoung Yi, Ho Kyeong Lee, Seoung Ju Park, Yong Chul Lee, Yang Keun Rhee, Heung Bum Lee
Korean J Intern Med. 2005;20(1):90-91. Published online March 31, 2005
Most broncholiths are related to infection with fungus or tuberculosis and they involve the lymph nodes; those cases that are caused by silicosis are rarely seen. Broncholith might lead complication such as bronchial rupture into the mediastinum, which can result in hemoptysis, cough, repeated pn..
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Case Report
Non-small Cell Lung Cancer Initially Presenting with Intracardiac Metastasis
Jung Han Kim, Joo Young Jung, Young Iee Park, Sang Ik Hwang, Chull Sung Jung, Sang Hak Lee, Chong Woo Yoo
Korean J Intern Med. 2005;20(1):86-89. Published online March 31, 2005
Intracardiac metastasis as the initial presentation of malignant neoplasm is very rare. We report here on a 64-year-old man with non-small cell lung cancer (NSCLC) initially presenting with intracardiac metastasis which was identified with 18-F fluorodeoxyglucose positron emission tomography (FDG..
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Case Report
Acute Exacerbation of Hepatitis in Liver Cirrhosis with Very High Levels of alpha-Fetoprotein But No Occurrence of Hepatocellular Carcinoma
Jin Soo Bae, Sang Jong Park, Kwang Bo Park, So Ya Paik, Jin Kyung Ryu, Chang Kyu Choi, Tae Joon Hwang
Korean J Intern Med. 2005;20(1):80-85. Published online March 31, 2005
Aminotransferase levels do not always increase during acute hepatitis or during an acute flare-up of chronic hepatitis. Persistently increased levels of serum alpha-Fetoprotein in an adult with liver disease suggest not only the presence or progression of hepatocellular carcinoma or its recurrenc..
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Case Report
Ileovesical Fistula Caused by Hepatocellular Carcinoma
Jeong Rae Byun, Sang Hee Cho, Deok Hwan Yang, Yeo Kyeoung Kim, Jae Kyun Ju, Sung Kyu Choi, Ik Joo Chung
Korean J Intern Med. 2005;20(1):76-79. Published online March 31, 2005
Ileovesical fistula is a very rare clinical entity, the most frequent cause of which is Crohn's disease. Furthermore, it is an exceptionally rare complication of malignancies. We experienced one case of ileovesical fistula which had been caused by hepatocellular carcinoma (HCC) arising from the n..
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Case Report
Solitary Intra-abdominal Tuberculous Lymphadenopathy Mimicking Duodenal GIST
You Sun Kim, Jeong Seop Moon, Jung Whan Lee, Il Kim, Soo Hyung Ryu, In Wook Paik
Korean J Intern Med. 2005;20(1):72-75. Published online March 31, 2005
Tuberculosis remains prevalent in developing countries and has recently re-emerged in the Western world. Intra-abdominal tuberculosis can mimic a variety of other abdominal disorders, and here we describe a patient with solitary tuberculous mesenteric lymphadenopathy mimicking duodenal gastrointe..
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Case Report
Cases of Swallow Syncope Induced by the Activation of Mechanorecepters in the Lower Esophagus
Ki Hoon Kang, Wook Hyun Cho, Myung Chan Kim, Hee Jong Chang, Jae Il Chung, Dong Jun Won
Korean J Intern Med. 2005;20(1):68-71. Published online March 31, 2005
Swallowing is a rare cause of neurally mediated syncope. The mechanism of swallow syncope that contributes to hypotension, bradycardia, or to both is complex. A 59-year-old man had experienced a recurrent loss of consciousness during swallowing of carbonated beverages or sticky foods. Another 59-..
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