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Original Article
Efficacy and Safety of Monthly 150 mg Oral Ibandronate in Women with Postmenopausal Osteoporosis: A Systematic Review and Meta-analysis of Randomized Controlled Trials
Young Ho Lee, Gwan Gyu Song
Korean J Intern Med. 2011;26(3):340-347. Published online September 13, 2011
Background/AimsThe aim of this study was to assess the efficacy and safety of monthly oral 150 mg ibandronate in women with postmenopausal osteoporosis (PMO). MethodsA systematic review and meta-analysis were performed to determine treatment eff..
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Original Article
Effects of D-003 (10 mg/day) on Bone Mineral Density of the Lumbar Spine and Femoral Neck in Postmenopausal Women: A Randomized, Double-Blinded Study
Alfredo Ceballos, Gladys Castaño, Sarahí Mendoza, Juan González, Rosa Mas, Lilia Fernández, José Illnait, Meilis Mesa, Rafael Gámez, Julio César Fernández, Ricardo Telles, Duany Marrero, Mainel Gómez Eng, Dalmer Ruiz, Yunaisi Jardines
Korean J Intern Med. 2011;26(2):168-178. Published online June 1, 2011
Background/AimsIncreased osteoclast activity is a pivotal finding in osteoporosis. This increase is mediated via the mevalonate-to-cholesterol pathway, which is involved in producing the intermediates required for osteoclast activity. D-003, a mixture of high molecular weight ..
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Original Article
Regional Anticoagulation with Citrate is Superior to Systemic Anticoagulation with Heparin in Critically Ill Patients Undergoing Continuous Venovenous Hemodiafiltration
Joon-Sung Park, Gheun-Ho Kim, Chong Myung Kang, Chang Hwa Lee
Korean J Intern Med. 2011;26(1):68-75. Published online March 2, 2011
Background/AimsShort hemofilter survival and anticoagulation-related life-threatening complications are major problems in systemic anticoagulation with heparin (SAH) for continuous renal replacement therapy (CRRT). The present study examined if regional anticoagulation with ci..
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Original Article
Combination of Uric Acid and NT-ProBNP: A More Useful Prognostic Marker for Short-Term Clinical Outcomes in Patients with Acute Heart Failure
Hyoung-Seob Park, Hyungseop Kim, Ji-Hyun Sohn, Hong-Won Shin, Yun-Kyeong Cho, Hyuck-Jun Yoon, Chang-Wook Nam, Seung-Ho Hur, Yoon-Nyun Kim, Kwon-Bae Kim, Hee-Joon Park
Korean J Intern Med. 2010;25(3):253-259. Published online August 31, 2010
Background/AimsIn patients with heart failure (HF), N-terminal prohormone brain natriuretic peptide (NT-ProBNP) is a standard prognostic indicator. In addition, uric acid (UA) was recently established as a prognostic marker for poor outcome in chronic HF. The aim of this stud..
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Original Article
Clinical Value of Serum Uric Acid in Patients with Suspected Coronary Artery Disease
Hong Euy Lim, Seong Hwan Kim, Eung Ju Kim, Jin Won Kim, Seung Woon Rha, Hong Seog Seo, Chang Gyu Park
Korean J Intern Med. 2010;25(1):21-26. Published online February 26, 2010
Background/AimsAlthough increased serum uric acid (SUA) concentrations are commonly encountered in patients with risk factors for coronary artery disease (CAD), the clinical value of SUA has not been established. MethodsThe study group comprised..
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Original Article
Effect of the Combined Use of Tramadol and Milnacipran on Pain Threshold in an Animal Model of Fibromyalgia
Seong-Ho Kim, Junhwa Song, Hyunil Mun, Keon Uk Park
Korean J Intern Med. 2009;24(2):139-142. Published online June 8, 2009
Background/AimsAcidic saline injections produce mechanical hyperresponsiveness in male Sprague-Dawley rats. We investigated the effect of milnacipran in conjunction with tramadol on the pain threshold in an acidic saline animal model of pain. Methods
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Original Article
Effect of High-Dose Intravenous N-acetylcysteine on the Concentration of Plasma Sulfur-Containing Amino Acids
Sae-Yong Hong, Hyo-Wook Gil, Jong-Oh Yang, Eun-Young Lee, Hyung-Kee Kim, Soo-Hyun Kim, Young-Ho Chung, Eun-Mi Lee, Soo-Kyung Hwang
Korean J Intern Med. 2005;20(3):217-223. Published online September 30, 2005
BackgroundThe purpose of this study was to determine the adequate loading and maintenance doses of N-acetylcyseteine (NAC) for patients suffering from acute ROS-induced injury. MethodsConcentrations of extra cellular NAC, cysteine (Cys), cystine..
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