|
Letter to the editor
Complete recovery of pyoderma gangrenosum after successful treatment of underlying hairy cell leukemia with cladribine
Anıl Tombak, Sinan Aygün, Ebru Serinsöz, Eyüp Naci Tiftik
Korean J Intern Med. 2015;30(5):739-741. Published online August 27, 2015
|
|
|
Cardiology / Original Article
A pharmacodynamic study of the optimal P2Y12 inhibitor regimen for East Asian patients with acute coronary syndrome
Ji Hyun Lee, Sung Gyun Ahn, Bonil Park, Sang Wook Park, Yong Seok Kang, Jun-Won Lee, Young Jin Youn, Min-Soo Ahn, Jang-Young Kim, Byung-Su Yoo, Seung-Hwan Lee, Junghan Yoon
Korean J Intern Med. 2015;30(5):620-628. Published online August 27, 2015
Background/Aims: Newer P2Y12 inhibitors, such as prasugrel and ticagrelor, have greater antiplatelet efficacy but may increase the risk of bleeding. In this study, we compared the pharmacodynamic efficacy of prasugrel and ticagrelor in East Asian patients with acute coronary syndrome (ACS..
|
|
|
Rheumatology / Original Article
Predictive factors of radiographic progression in ankylosing spondylitis
Hyungjin Kim, Jaejoon Lee, Joong Kyong Ahn, Jiwon Hwang, Eun-Jung Park, Hyemin Jeong, Hoon-Suk Cha, Eun-Mi Koh
Korean J Intern Med. 2015;30(3):391-397. Published online April 29, 2015
Background/Aims: The course of ankylosing spondylitis (AS) is rather variable, and the factors that predict radiographic progression remain largely obscure. In this study, we tried to determine the clinical factors and laboratory measures that are useful in predicting the radiographic progression of..
|
|
|
Rheumatology / Original Article
SKI306X inhibition of glycosaminoglycan degradation in human cartilage involves down-regulation of cytokine-induced catabolic genes
Choong Hyeok Choi, Tae-Hwan Kim, Yoon-Kyoung Sung, Chan-Bum Choi, Young-In Na, Hunseung Yoo, Jae-Bum Jun
Korean J Intern Med. 2014;29(5):647-655. Published online August 28, 2014
Background/Aims: SKI306X, a mixed extract of three herbs, Clematis mandshurica (CM), Prunella vulgaris (PV), and Trichosanthes kirilowii (TK), is chondroprotective in animal models of osteoarthritis (OA). The objectives of this study were to invest..
|
|
|
Cardiology / Original Article
Efficacy and safety of antiplatelet-combination therapy after drug-eluting stent implantation
Yun-Kyeong Cho, Chang-Wook Nam, Hyoung-Seob Park, Hyuck-Jun Yoon, Hyungseop Kim, Seung-Ho Hur, Yoon-Nyun Kim, Jang-Hoon Lee, Dong-Heon Yang, Bong-Ryeol Lee, Byung-Chun Jung, Woong Kim, Jong-Seon Park, Jin-Bae Lee, Kee-Sik Kim, Kwon-Bae Kim
Korean J Intern Med. 2014;29(2):210-216. Published online February 27, 2014
Background/Aims: Combination single-pill therapy can improve cost-effectiveness in a typical medical therapy. However, there is a little evidence about the efficacy and tolerability of combination single-pill antiplatelet therapy after percutaneous coronary intervention (PCI) with drug-eluting stent..
|
|
|
Rheumatology / Original Article
Greater prevalence of seropositivity for anti-cyclic citrullinated peptide antibody in unaffected first-degree relatives in multicase rheumatoid arthritis-affected families
Seong-Kyu Kim, Jisuk Bae, Hwajeong Lee, Ji Hun Kim, Sung-Hoon Park, Jung-Yoon Choe
Korean J Intern Med. 2013;28(1):45-53. Published online December 28, 2012
Background/AimsThis study determined the prevalence and determinants of seropositivity for rheumatoid factor (RF), anti-cyclic citrullinated peptide (anti-CCP) antibody, and anti-mutated citrullinated vimentin (anti-MCV) antibody in unaffected first-degree relatives (FDRs) of ..
|
|
|
Case Report
Complete Atrioventricular Block in Adult Sjögren's Syndrome with Anti-Ro Autoantibody
Myung Jun Sung, Sung-Hoon Park, Seong-Kyu Kim, Young-Soo Lee, Chul-Yeon Park, Jung-Yoon Choe
Korean J Intern Med. 2011;26(2):213-215. Published online June 1, 2011
Anti-Ro autoantibody is associated with Sjögren's syndrome (SS), systemic lupus erythematosus (SLE), and neonatal lupus syndrome (i.e., congenital complete heart block in newborns). Generally, the adult atrioventricular (AV) node is believed to be relatively resistant to the scarring effects of..
|
|
|
Original Article
Detection of Clopidogrel Hyporesponsiveness Using a Point-of-Care Assay and the Impact of Additional Cilostazol Administration after Coronary Stent Implantation in Diabetic Patients
Tae-Hyun Yang, Doo-Il Kim, Dong-Kie Kim, Jae-Sik Jang, Ung Kim, Sang-Hoon Seol, Dae-Kyeong Kim, Geu-Ru Hong, Jong-Seon Park, Dong-Gu Shin, Young-Jo Kim, Yun-Kyeong Cho, Chang-Wook Nam, Seung-Ho Hur, Kwon-Bae Kim, Dong-Soo Kim
Korean J Intern Med. 2011;26(2):145-152. Published online June 1, 2011
Background/AimsImpaired responsiveness to clopidogrel is common in patients with type 2 diabetes mellitus (DM). The aim of this study was to evaluate the clinical application of a point-of-care assay to detect impaired responsiveness to clopidogrel after coronary stent implant..
|
|
|
Case Report
Lymphocytic Interstitial Pneumonia in Primary Sjögren's Syndrome: A Case Report
Ji-Young Kim, Sung-Hoon Park, Seong-Kyu Kim, Dae-Sung Hyun, Yoon Seup Kum, Kyung-Jae Jung, Jung-Yoon Choe
Korean J Intern Med. 2011;26(1):108-111. Published online March 2, 2011
Sjögren's syndrome (SS) is an autoimmune disorder in which lymphocytes infiltrate the exocrine glands, resulting in the development of sicca symptoms. Lymphocytes may also invade various other organs and cause diverse symptoms. Interstitial pneumonia has been observed frequently in SS patients...
|
|
|
Original Article
The Impact of Generic Clopidogrel Bisulfate on Platelet Inhibition in Patients with Coronary Artery Stents: Results of the ACCEL-GENERIC Study
Young-Hoon Jeong, Jin-Sin Koh, Min-Kyung Kang, Yeon-Jeong Ahn, In-Suk Kim, Yongwhi Park, Seok-Jae Hwang, Choong Hwan Kwak, Jin-Yong Hwang
Korean J Intern Med. 2010;25(2):154-161. Published online June 1, 2010
Background/AimsIn patients with coronary artery stents, the cost of clopidogrel has been cited as a factor in the premature discontinuation of therapy. Thus, the introduction of lower-cost generic clopidogrel may increase patient compliance. However, platelet inhibition by ge..
|
|
|
Case Report
A Case of Green Urine after Ingestion of Herbicides
Yun-Suk Shim, Hyo-Wook Gil, Jong-Oh Yang, Eun-Young Lee, Soo-Hyun Kim, Sae-Yong Hong
Korean J Intern Med. 2008;23(1):42-44. Published online March 20, 2008
The development of discolored urine may have many possible causes. Here we present the case of a 76-year-old woman who was admitted after ingesting the inorganic herbicides, mefenacet and imazosulfuron. Her urine color changed to green almost immediately. Since the patient had no specific medicat..
|
|
|
Case Report
Pulmonary Nodular Lymphoid Hyperplasia Associated with Sjögren's Syndrome
Moo-Kon Song, Young-Mi Seol, Young-Eun Park, Yun-Seong Kim, Min-Ki Lee, Chang-Hun Lee, Yeon-Ju Jeong
Korean J Intern Med. 2007;22(3):192-196. Published online September 30, 2007
Pulmonary nodular lymphoid hyperplasia (NLH) is a term first suggested by Kradin and Mark to describe one or more pulmonary nodules or localized lung infiltrates consisting of reactive lymphoid proliferation. To date, there have been only a few cases of pulmonary NLH reported associated with aut..
|
|
|
Case Report
Coronary Artery Intervention after Cytostatics Treatment in Unstable Angina Patient with Essential Thrombocythemia. A Case Report and Literature Review
Hyun Chang, Chi Young Shim, June-Won Cheong, Ju-Yeon Pyo, Young Guk Ko, Donghoon Choi, Yangsoo Jang
Korean J Intern Med. 2006;21(2):146-149. Published online June 30, 2006
Essential thrombocythemia (ET) is a clonal disorder of myeloid stem cells that causes thrombocytosis. As a result, ET can lead to vascular thrombosis and tissue ischemia; the association of coronary artery abnormalities such as myocardial infarction or unstable angina is rare. Here we describe a ..
|
|
|
Case Report
Concurrence of Sjögren's Syndrome in a Patient with Chlamydia-induced Reactive Arthritis; An Unusual Finding
Hyun Kyu Chang, Ki Tae Bang, Bo Han Lee, Jung Hyuk Kim, Kang Woo Bae, Myong Jin Kim, Seong-Kyu Kim
Korean J Intern Med. 2006;21(2):116-119. Published online June 30, 2006
A 40-year-old Korean man presented with painful swelling and tenderness of both ankle joints as well as the plantar surfaces of both feet, along with inflammatory back pain, and a purulent discharge from the urethral orifice. The patient also complained of sicca-like symptoms including dry eyes a..
|
|
|
Case Report
Clear Cell Hepatocellular Carcinoma with Spontaneous Regression of Primary and Metastatic Lesions
Seong-Woo Jeon, Myung-Kwon Lee, Young-Doo Lee, Hyang-Eun Seo, Chang-Min Cho, Won-Young Tak, Young-Oh Kweon
Korean J Intern Med. 2005;20(3):268-273. Published online September 30, 2005
The prognosis of advanced hepatocellular carcinoma (HCC) tends to be poor. Spontaneous regression of this lesion is extremely rare. In this report, we describe a case of HCC which spontaneously regressed along with a metastatic lesion of the chest wall. A huge HCC in the right lobe, the largest ..
|
|
|
Original Article
Comparison of antiplatelet treatment in patients with clopidogrel nonresponders with or without carriage of CYP2C19 polymorphism
Yun Myoung Ko, Jeong Kyung Kim, Jeong Hee Kim, Sang-Ho Park, Rak Kyeong Choi
Received October 31, 2017 Accepted January 8, 2018 Published online May 31, 2018
Background/Aims: Several interventions exist for overcoming high platelet reactivity (HPR) on clopidogrel therapy. The goal of this study was to identify strategies that improve inhibition of platelet reactivity in clopidogrel nonresponders with or without loss of function CYP2C19 genotypes, ..
|
|
|
Original Article
Effect of tegoprazan on temporal variability of platelet reactivity in patients treated with clopidogrel after coronary stenting
Oh-Hyun Lee, Ji Woong Roh, Yongcheol Kim, Eui Im, Deok-Kyu Cho
Received November 22, 2024 Accepted February 7, 2025 Published online March 25, 2025
Background/Aims: Data on the interactions between clopidogrel and tegoprazan are limited. We compared the effects of tegoprazan and proton-pump inhibitors (PPIs) on platelet reactivity.
Methods: Using database data from March 2020 to January 2023, we retrospectively evaluated 262 patients who were ..
|
|
|
