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Letter to the editor
Synchronous parathyroid carcinoma and papillary thyroid carcinoma in a patient with long-standing schizophrenia
Cho-Ok Baek, Ki Hoi Kim, Sun Kyung Song
Korean J Intern Med. 2017;32(6):1104-1107. Published online October 17, 2017
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Rheumatology / Original Article
The role of 18F-fluorodeoxyglucose positron emission tomography in the assessment of disease activity of adult-onset Still’s disease
Young-Sil An, Chang-Hee Suh, Ju-Yang Jung, Hundo Cho, Hyoun-Ah Kim
Korean J Intern Med. 2017;32(6):1082-1089. Published online December 7, 2016
Background/Aims: 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) has been suggested as a reliable imaging technique for monitoring of disease activity in patients with adult-onset Still’s disease (AOSD). Therefore, we investigated the ..
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Infectious diseases / Original Article
Diagnostic role of mean platelet volume and neutrophil to lymphocyte ratio in childhood brucellosis
Şefika Elmas Bozdemir, Yasemin Ay Altıntop, Salih Uytun, Humeyra Aslaner, Yasemin Altuner Torun
Korean J Intern Med. 2017;32(6):1075-1081. Published online December 14, 2016
Background/Aims: Brucellosis patients present various non-specific clinical symptoms, such as fever, fatigue, sweating, joint pain, arthritis, myalgia, and headache. Based on the nonspecifity of its clinical signs and symtoms, we decided to evaluate whether mean platelet volume (MPV) , neutrophil to..
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Hemato-oncology / Original Article
Analgesic effect of quetiapine in a mouse model of cancer-induced bone pain
Mi Hwa Heo, Jin Young Kim, Ilseon Hwang, Eunyoung Ha, Keon Uk Park
Korean J Intern Med. 2017;32(6):1069-1074. Published online January 20, 2017
Background/Aims: Cancer-induced bone pain (CIBP) is one of the most common pains in patients with advanced neoplasms. Because of treatment-associated side effects, more than half of cancer patients are reported to have inadequate and undermanaged pain control. New mechanism-based therapies must be d..
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Nephrology / Original Article
Impact of random urine proteinuria on maternal and fetal outcomes of pregnancy: a retrospective case-control study
Eun Hui Bae, Jong Woon Kim, Hong Sang Choi, Seong Kwon Ma, Soo Wan Kim
Korean J Intern Med. 2017;32(6):1062-1068. Published online October 13, 2016
Background/Aims: Proteinuria is associated with hypertension and preeclampsia in pregnancy. However, the impact of random urine proteinuria on fetal and maternal outcomes has not been established. We investigated the influence of random urine proteinuria on the clinical outcomes of pregnancy.
Metho..
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Nephrology / Original Article
Blocking junctional adhesion molecule C promotes the recovery of cisplatin-induced acute kidney injury
Sun Chul Kim, Yoon Sook Ko, Hee Young Lee, Myung-Gyu Kim, Sang-Kyung Jo, Won-Yong Cho
Korean J Intern Med. 2017;32(6):1053-1061. Published online February 15, 2017
Background/Aims: Recent findings have demonstrated the occurrence of neutrophil transendothelial migration in the reverse direction (reverse TEM) and that endothelial junctional adhesion molecule C (JAM-C) is a negative regulator of reverse TEM. In this study, we tested the effects of a JAM-C blocki..
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Pulmonology / Original Article
Epidemiological trend of pulmonary thromboembolism at a tertiary hospital in Korea
Tae Yun Park, Jae-Woo Jung, Jae Chol Choi, Jong Wook Shin, Jae Yeol Kim, Byoung Whui Choi, In Won Park
Korean J Intern Med. 2017;32(6):1037-1044. Published online March 13, 2017
Background/Aims: Despite increasing interest in pulmonary thromboembolism (PTE), data on recent trends in PTE incidence are limited. This study evaluated the recent incidence rate of PTE.
Methods: We performed a retrospective chart review of patients with PTE admitted to Chung-Ang University Hospit..
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Endocrinology-metabolism / Review
Combination therapy of oral hypoglycemic agents in patients with type 2 diabetes mellitus
Min Kyong Moon, Kyu Yeon Hur, Seung-Hyun Ko, Seok-O Park, Byung-Wan Lee, Jin Hwa Kim, Sang Youl Rhee, Hyun Jin Kim, Kyung Mook Choi, Nan-Hee Kim; on behalf of the Committee of Clinical Practice Guidelines of the Korean Diabetes Association
Korean J Intern Med. 2017;32(6):974-983. Published online October 27, 2017
The Korean Diabetes Association (KDA) recently updated the Clinical Practice Guidelines on antihyperglycemic agent therapy for adult patients with type 2 diabetes mellitus (T2DM). In combination therapy of oral hypoglycemic agents (OHAs), general recommendations were not changed from those of the 20..
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Endocrinology-metabolism / Review
Insulin therapy for adult patients with type 2 diabetes mellitus: a position statement of the Korean Diabetes Association, 2017
Byung-Wan Lee, Jin Hwa Kim, Seung-Hyun Ko, Kyu Yeon Hur, Nan-Hee Kim, Sang Youl Rhee, Hyun Jin Kim, Min Kyong Moon, Seok-O Park, Kyung Mook Choi; on behalf of the Committee of Clinical Practice Guideline of Korean Diabetes Association
Korean J Intern Med. 2017;32(6):967-973. Published online October 23, 2017
The Korean Diabetes Association (KDA) has regularly updated its Clinical Practice Guidelines. In 2017, the KDA published a position statement on the use of antihyperglycemic agents for patients with type 2 diabetes mellitus (T2DM). Growing evidence from new multinational clinical trials using novel ..
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Endocrinology-metabolism / Review
Monotherapy in patients with type 2 diabetes mellitus
Sang Youl Rhee, Hyun Jin Kim, Seung-Hyun Ko, Kyu Yeon Hur, Nan-Hee Kim, Min Kyong Moon, Seok-O Park, Byung-Wan Lee, Kyung Mook Choi, Jin Hwa Kim; Committee of Clinical Practice Guideline of Korean Diabetes Association
Korean J Intern Med. 2017;32(6):959-966. Published online October 23, 2017
In order to improve the quality of life and to prevent chronic complications related to diabetes mellitus, intensive lifestyle modification and proper medication are needed from the early stage of diagnosis of type 2 diabetes mellitus (T2DM). When using the first medication for diabetic patients, th..
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Endocrinology-metabolism / Review
Antihyperglycemic agent therapy for adult patients with type 2 diabetes mellitus 2017: a position statement of the Korean Diabetes Association
Seung-Hyun Ko, Kyu Yeon Hur, Sang Youl Rhee, Nan-Hee Kim, Min Kyong Moon, Seok-O Park, Byung-Wan Lee, Hyun Jin Kim, Kyung Mook Choi, Jin Hwa Kim; Committee of Clinical Practice Guideline of Korean Diabetes Association
Korean J Intern Med. 2017;32(6):947-958. Published online October 23, 2017
In 2017, the Korean Diabetes Association (KDA) published a position statement on the use of antihyperglycemic agents for patients with type 2 diabetes mellitus (T2DM). The KDA regularly updates its Clinical Practice Guidelines, but since the last update in 2015, many results from clinical trials hav..
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Letter to the editor
Metronomic chemotherapy with capecitabine for metastatic colorectal cancer in very elderly patients
Yun Hwa Jung, Won Jik Lee, Jae Ho Byeon, In Kyu Lee, Chi Wha Han, In Sook Woo
Korean J Intern Med. 2017;32(5):926-929. Published online March 10, 2016
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Letter to the editor
Epiphora following chemotherapy with pemetrexed in patients with advanced non-small cell lung cancer
Yun Duk Jung, Sang Bin Lee, Yun Wha Jung, Jung Sub Song, In Sook Woo
Korean J Intern Med. 2017;32(5):923-925. Published online March 18, 2017
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Infectious diseases / Original Article
Clinical applications of interferon-γ releasing assays for cytomegalovirus to differentiate cytomegalovirus disease from bystander activation: a pilot proof-of-concept study
Sung-Han Kim, Ho-Su Lee, Hyun-Jung Lee, Sun-Mi Kim, Sung Shin, Sang-Hyoung Park, Kyung-Jo Kim, Young-Hoon Kim, Heungsup Sung, Sang-Oh Lee, Sang-Ho Choi, Suk-Kyun Yang, Yang Soo Kim, Jun Hee Woo, Duck-Jong Han
Korean J Intern Med. 2017;32(5):900-909. Published online August 23, 2017
Background/Aims: We evaluated the proposed clinical application of the combined interpretation of host factors and viral factors in two different cytomegalovirus (CMV) co-infection models.
Methods: We prospectively enrolled all human immunodeficiency virus non-infected patients with confirmed P..
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Hemato-oncology / Original Article
Clinical features and treatment outcomes of blastic plasmacytoid dendritic cell neoplasm: a single-center experience in Korea
Hae Su Kim, Hee-Jin Kim, Sun-Hee Kim, Joon Young Choi, Young Hyeh Ko, Won Seog Kim, Chul Won Jung, Seok Jin Kim
Korean J Intern Med. 2017;32(5):890-899. Published online August 18, 2017
Background/Aims: Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematologic malignancy that typically presents in the form of skin manifestations with or without lymph node and bone marrow involvement. Given its rarity and recent recognition as a distinct pathological entity, no stan..
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Cardiology / Original Article
Geographic and demographic variabilities of quantitative parameters in stress myocardial computed tomography perfusion
Jinoh Park, Hyun-Sook Kim, Hye Jeon Hwang, Dong Hyun Yang, Hyun Jung Koo, Joon-Won Kang, Young-Hak Kim
Korean J Intern Med. 2017;32(5):847-854. Published online July 28, 2017
Background/Aims: To evaluate the geographic and demographic variabilities of the quantitative parameters of computed tomography perfusion (CTP) of the left ventricular (LV) myocardium in patients with normal coronary artery on computed tomography angiography (CTA).
Methods: From a multicenter CTP r..
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Gastroenterology / Original Article
Factors impacting patient cooperation during elective gastroscopy
Sang Pyo Lee, In-Kyung Sung, Jeong Hwan Kim, Sun-Young Lee, Hyung Seok Park, Chan Sup Shim
Korean J Intern Med. 2017;32(5):819-826. Published online August 22, 2017
Background/Aims: Some people have difficulty tolerating upper endoscopy. The cause of and risk factors for this are not well known. The aim of this study was to investigate the factors involved in poor cooperation during screening upper endoscopy.
Methods: A total of 4,422 subjects who underwent a h..
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Infectious diseases / Review
Voriconazole-refractory invasive aspergillosis
Se Yoon Park, Jung-A Yoon, Sung-Han Kim
Korean J Intern Med. 2017;32(5):805-812. Published online August 24, 2017
Invasive aspergillosis (IA) is one of the most common life-threatening complications in immunocompromised patients. Voriconazole is currently the drug of choice for IA treatment. However, some patients with IA suffer clinical deterioration despite voriconazole therapy. Management of voriconazole-ref..
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Hemato-oncology / Review
Targeted therapy of ovarian cancer including immune check point inhibitor
Jin Young Kim, Chi Heum Cho, Hong Suk Song
Korean J Intern Med. 2017;32(5):798-804. Published online August 22, 2017
Epithelial ovarian cancer is the eighth most common cause of cancer-related deaths in women because most patients present with advanced stage disease at the time of diagnosis. Although cytoreductive surgery and platinum-based chemotherapy remain the gold standards of treatment, the recurrence rate o..
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Letter to the editor
An isolated cardiac relapse after allogeneic hematopoietic stem cell transplantation for acute
lymphoblastic leukemia
Kiju Chang, Dae-Young Kim, Kyoo-Hyung Lee, Jooryung Huh, Joon-Won Kang, Dong Yeol Shin, Dae-Hee Kim
Korean J Intern Med. 2017;32(4):753-757. Published online February 2, 2016
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